Clinical Trials on Primary Immune Deficiency in Adults in United Kingdom

Total 7037 results

Gilead Sciences

Completed

ROCKET I - Randomized Open Label Switch for Cholesterol Elevation on Kivexa Evaluation Trial (ROCKET I)

HIV Infections

United Kingdom
Green Cross Corporation
Atlantic Research Group

Completed

Phase 3 Study of Immune Globulin Intravenous (Human)IVIG-SN™ in Subjects With Primary Immunodeficiency

Immunologic Deficiency Syndrome

United States, Canada
PepTcell Limited

Completed

HIV Vaccine Study in HIV Positive Patients

HIV Infections

United Kingdom
University of Ulster
Western Health and Social Care Trust; University College Hospital Galway; Letterkenny...

Completed

Remote Monitoring of Diabetes in Pregnancy: a Feasibility Study (Tele-Mum)

Gestational Diabetes

Ireland, United Kingdom
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Reducing Heavy Drinking to Optimize HIV/AIDS Treatment and Prevention (DAWN)

Reduction in Heavy Drinking in Patients With HIV

United States
King's College Hospital NHS Trust

Completed

Depth of Anaesthesia and Postoperative Cognitive Decline in Patients Undergoing Heart Surgery

Postoperative Delirium | Postoperative Cognitive Dysfunction | Cardiac Bypass Surgery in Adult Patients 65 Years and Older

United Kingdom
Rochester General Hospital

Completed

Humoral Immunodeficiency With Rituximab and Therapy With Subcutaneous Ig

Secondary Immune Deficiency

United States
Icahn School of Medicine at Mount Sinai
American Heart Association

Completed

Family-based Approach to Promotion of Health - FAMILIA (Project 2) (FAMILIA)

Atherosclerosis | Lifestyle Intervention | Promoting Cardiovascular Health in Adults

United States
David Williams

Active, not recruiting

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Gene Therapy | Severe Combined Immunodeficiency, X Linked

United States, United Kingdom
Intellia Therapeutics

Enrolling by invitation

Long-Term Follow-Up (LTFU) of Subjects Treated With NTLA 2002

Hereditary Angioedema

France, New Zealand, United Kingdom, Netherlands
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Completed

Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia in Pediatric PIDD Subjects

Primary Immunodeficiency Diseases (PID)

Denmark, United Kingdom, Czechia, France, Greece, Hungary, Slovakia, Sweden
University of Colorado, Denver
Colorado Clinical & Translational Sciences Institute

Recruiting

Mechanisms of Immune Deficiency

Immune Deficiency

United States
Chelsea and Westminster NHS Foundation Trust
Merck Sharp & Dohme LLC; Imperial College London; University of Liverpool

Completed

Pharmacokinetics of Plasma Doravirine Once Daily Over 72 Hours Following Drug Intake Cessation in Healthy Volunteers

Human Immunodeficiency Virus

United Kingdom
PENTA Foundation

Completed

Pharmacokinetic (PK) Study of Twice Daily vs Once Daily Lamivudine (3TC) and Abacavir (ABC) as Part of Combination Antiretroviral Therapy (ART) in HIV Infected Children (PENTA 13)

HIV Infection

United Kingdom
ViiV Healthcare

Recruiting

A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants

HIV Infections

United Kingdom
Genethon
Institute of Child Health; Great Ormond Street Hospital for Children NHS Foundation...

Completed

Gene Therapy for Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

United Kingdom
Imperial College London

Completed

Financial Incentives to Improve Asthma (FINA)

Medication Adherence | Asthma in Children

United Kingdom
NHS Lothian

Completed

Delivery of Audiovisual Information on Early Medical Abortion (EMAVID)

Abortion in First Trimester | Abortion Early

Sweden, United Kingdom, France
International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity Study of SeV-G(NP) HIV Vaccine Administered Intranasally and Ad35-GRIN HIV Vaccine Given Intramuscularly in Prime-Boost Regimens in HIV-Uninfected Volunteers

HIV Infections

United Kingdom, Kenya, Rwanda
University of Florida
National Institute of Nursing Research (NINR); National Institutes of Health...

Completed

Study To Analyze Memory/Thinking Problems In Older Adults After Surgery (POCD)

Post-Operative Cognitive Decline in Older Adults

United States
University Hospital, Geneva
Food Allergy Research & Education; Allergistiftung Ulrich Müller

Completed

Tree Nuts Allergies: Does a Single Nut Allergy Necessitate the Dietary Eviction of Other Tree Nuts? (ProNut)

Nut Allergy in Children

United Kingdom, Switzerland, Spain
Genzyme, a Sanofi Company

Completed

A Study of AMD11070 in HIV-infected Patients Carrying X4-tropic Virus

HIV Infections | X4 Tropic Virus

United States, United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Food Allergy in the Brain (FAB)

Anxiety | Cognitive Symptom | Food Allergy | Food Allergy in Children

United Kingdom
Amgen

Completed

An Open-Label Phase I/II Study of Recombinant Granulocyte Colony Stimulating Factor (r-metHuG-CSF) and Recombinant Erythropoietin (rHuEPO) Given Subcutaneously Along With Zidovudine (AZT) to Patients With the Acquired Immune Deficiency Syndrome (AIDS) or Severe AIDS-Related Complex (ARC)

HIV Infections

United States
Imperial College London

Completed

Clinical Trial of HIV Vaccine Combinations in Healthy Men and Women (Ad4HIV)

Human Immunodeficiency Virus

United Kingdom
King's College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Recruiting

The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
Virginia Polytechnic Institute and State University

Completed

Impact Loading Effect on Bone Biomarkers in Female Runners

Relative Energy Deficiency in Sport

United States
University of Virginia
CSL Behring; Jeffrey Modell Foundation

Completed

Undetectable IgE as a Sentinel Biomarker for Humoral Immunodeficiency

Immune Deficiency

United States
University Hospitals of North Midlands NHS Trust

Recruiting

Performance and Adherence in Children Using Spacers (OUTER-SPACERS)

Asthma | Asthma in Children

United Kingdom
Bellicum Pharmaceuticals

Terminated

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Hemoglobinopathies | Hemophagocytic Lymphohistiocytosis | Metabolic Disorders | Primary Immune Deficiency Disorders | Inherited Bone Marrow Failure Syndrome

United States
Boston Scientific Corporation

Terminated

Field Shape and Amplitude Sensitivity Exploratory Study (CONTOUR Study)

Chronic Neuropathic Pain in the Low Back and Legs

United Kingdom
University of Ulster
Northern Ireland Clinical Research Service

Recruiting

Aflo™ Device Trial (AFLO)

Asthma | Asthma in Children

United Kingdom
Imperial College London

Completed

Mechanisms of Interplay Between Allergy and Viruses in Asthma

Rhinovirus Infection in Asthma

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Evaluation of Azidothymidine (AZT) in Children With Acquired Immune Deficiency Syndrome (AIDS) or AIDS Related Complex (ARC)

HIV Infections

United States
National Cancer Institute (NCI)

Completed

Gene Therapy for Patients With Leukocyte Adherence Deficiency (Follow-Up of Phase 1 Trial)

Leukocyte Adhesion Deficiency Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Completed

Interferon Gamma to Treat Leukocyte Adhesion Deficiency Type I

Leukocyte Adhesion Deficiency Syndrome

United States
Imperial College London

Completed

Positive Attitudes Concerning Infant Feeding- a Questionnaire for Women Living With HIV (PACIFY)

Human Immunodeficiency Virus

United Kingdom
University of Surrey
European Commission

Completed

A Safety Study Of A Single Vaginal Administration Of P2G12 Antibody In Healthy Female Subjects

Human Immunodeficiency Virus

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Absolute Bioavailability of BMS-626529 After Oral and Intravenous Dosing

Infection, Human Immunodeficiency Virus

United Kingdom
St Stephens Aids Trust

Completed

PK of Tenofovir, Emtricitabine and Efavirenz in Healthy Volunteers

HIV Infections | HIV Infection

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Terminated

Efficacy, Tolerability and Acceptability of Biktarvy by TPLWH

Human Immunodeficiency Virus

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Bioavailability of BMS-626529 in Healthy Subjects From Prototype Low Dose Extended Release Formulations (Part 1) and Prototype Extended Release Multi-particulate Formulations (Part 2) of BMS-663068 Relative to 600 mg Extended Release Tablet

Infection, Human Immunodeficiency Virus

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Relative Bioavailability Study With BMS-955176

Infection, Human Immunodeficiency Virus

United Kingdom
King's College London
Action Medical Research

Unknown

The EAT-On Study: Sensitisation, Allergy and Child Health

Obesity, Childhood | Food Allergy in Children | Food Allergen Sensitisation

United Kingdom
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

3-Tesla MRI Response to TACE in HCC (Liver Cancer)

Advanced Adult Primary Liver Cancer | Localized Resectable Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Adult Primary Hepatocellular Carcinoma | Stage A Adult Primary Liver Cancer (BCLC) | Stage B Adult Primary Liver Cancer (BCLC)

United States
Garcia, Jose M., MD, PhD

Completed

Metabolic and QOL Effects of GH Treatment in Patients With TBI and AGHD

Adult-Onset Growth Hormone Deficiency

United States
Children's Hospital of Philadelphia
University of California, San Francisco

Recruiting

Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies

Immunodeficiencies | Immune Dysregulation Syndromes

United States
Lederle Laboratories

Completed

A Multi-Center, Open-Label, Ascending, Multiple Oral Dose, Safety, Tolerance and Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Patients With Acquired Immune Deficiency Syndrome (AIDS) or AIDS-Related Complex (ARC)

HIV Infections

United States
Royal Marsden NHS Foundation Trust

Unknown

Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer

Sarcoma | Cervical Cancer | Testicular Germ Cell Tumor | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Endometrial Cancer | Radiation Toxicity | Vaginal Cancer | Gastrointestinal Complications | Long-term Effects Secondary to Cancer Therapy in Adults

United Kingdom
Rochester General Hospital

Completed

Humoral Immunodeficiency in CLL and Therapy With Subcutaneous Ig

Secondary Immune Deficiency Disorder

United States

Clinical Trials on Primary Immune Deficiency in Adults in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Lithuania

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Rare Diseases

Drug Interventions

Dietary Supplements

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