Clinical Trials on Primary Immuno-Deficiencies in Japan

Total 2151 results

GlaxoSmithKline

Completed

Phase 1 Study of GSK2315698 in Healthy Japanese Subjects

Amyloidosis

Japan
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving ABBV-383 as an Intravenous (IV) Infusion

Immunoglobulin Light Chain (AL) Amyloidosis

Japan, United States, Australia
Pfizer

Recruiting

Vyndaqel Capsules Special Investigation (ATTR-CM)

Transthyretin (TTR) Amyloid Cardiomyopathy

Japan
Mitsubishi Tanabe Pharma Corporation

Completed

Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis

Japanese Patients With ALS

Japan
Chiba University

Completed

Open-label Clinical Trial of Lacosamide in ALS

Amyotrophic Lateral Sclerosis

Japan
Yoshino Neurology Clinic

Unknown

Efficacy and Safety of YAM80 in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Japan
Mitsubishi Tanabe Pharma Corporation

Completed

Clinical Pharmacology Study of Oral Edaravone in Amyotrophic Lateral Sclerosis Patients With Gastrostomy

Japanese Patients With ALS

Japan
Mitsubishi Tanabe Pharma Corporation

Completed

Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS)

Japan
Eli Lilly and Company

Completed

A Study of Merestinib (LY2801653) in Japanese Participants With Advanced or Metastatic Cancer

Non-Hodgkin's Lymphoma | Solid Tumor | Metastatic Cancer | Cholangiocarcinoma | Advanced Cancer | Biliary Tract Carcinoma | Gall Bladder Carcinoma

Japan
Kyoto University
Pfizer; Kitasato University; Tokushima University; Tottori University

Recruiting

iPSC-based Drug Repurposing for ALS Medicine (iDReAM) Study

Amyotrophic Lateral Sclerosis

Japan
Mitsubishi Tanabe Pharma Corporation

Completed

Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Japan
Janssen Research & Development, LLC

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

Amyloidosis

United States, Netherlands, Belgium, Korea, Republic of, France, Sweden, Israel, Turkey, United Kingdom, Brazil, Canada, Mexico, Australia, Germany, Japan, Spain, Denmark, Italy, China, Greece, Poland, Hungary
Kinki University

Unknown

Efficacy and Safety of Tamibarotene(AM80) for Lupus Nephritis

Lupus Nephritis

Japan
Nagoya University
Rohto Pharmaceutical Co., Ltd.

Completed

The Clinical Trial of ADR-001 for IgA Nephropathy

Glomerulonephritis , IGA

Japan
Kagawa University

Unknown

A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy

Hypertension | Glomerulonephritis, IGA

Japan
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Primary Open Angle Glaucoma or Ocular Hypertension

Japan
Novartis Pharmaceuticals

Completed

An Extention Study of Safety of Canakinumab in Japanese Patients With Periodic Fever Syndromes

Periodic Fevers Syndrome

Japan
Takeda

Completed

An Extension Study of TAK-664 for Japanese People With Primary Immunodeficiency Disease

Primary Immunodeficiency Disease

Japan
Tokyo Medical University

Completed

Perampanel for Sporadic Amyotrophic Lateral Sclerosis (ALS)

ALS

Japan
Keio University

Unknown

Confocal Microscopy and Lacrimal Gland in Sjogren's Syndrome

Primary Sjogren's Syndrome

Japan
AstraZeneca

Recruiting

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis (OverTTuRe)

ATTR Amyloidosis

Spain, United States, Denmark, Japan, Sweden, United Kingdom
Prothena Biosciences Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis (AFFIRM-AL)

Light Chain (AL) Amyloidosis

United States, Korea, Republic of, Australia, Denmark, France, Italy, Spain, Israel, Taiwan, Austria, Canada, Czechia, Germany, Greece, Hungary, Japan, Netherlands, Poland, Portugal, Turkey, United Kingdom, Belgium, Ireland
Yakult Honsha Co., LTD
Japan Aerospace Exploration Agency

Active, not recruiting

Probiotics on Immune Function and Intestinal Microbiota in Astronauts Under Closed Microgravity Environment

Immune Function and Intestinal Microbiota

Japan
Alexion Pharmaceuticals, Inc.
Eidos Therapeutics, a BridgeBio company

Active, not recruiting

A Phase 3 Study of ALXN2060 in Japanese Participants With Symptomatic ATTR-CM

Symptomatic Transthyretin Amyloid Cardiomyopathy

Japan
Kyoto University

Withdrawn

Surgery With or Without Hepatic Arterial Chemotherapy in Treating Patients With Liver Cancer

Localized Resectable Adult Primary Liver Cancer | Stage III Childhood Liver Cancer

Japan
Satoshi Kusuda
Scientific Committee of Recurrent Wheezing

Completed

Effect of Palivizumab on Later Recurrent Wheezing in Preterm Infants

Asthma | Wheezing | Recurrent Wheezing

Japan
Pfizer

Completed

The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M Transthyretin

Transthyretin Familial Amyloid Polyneuropathy

Japan
Kindai University
Janssen Pharmaceutical K.K.

Recruiting

Study to Evaluate ctDNA of mCSPC Patients Receiving Apalutamide in Japan (CUARTET)

Metastatic Castration-sensitive Prostate Cancer

Japan
Takeda

Recruiting

A Survey of Icatibant in Pediatric Participants With Hereditary Angioedema

Hereditary Angioedema (HAE)

Japan
GlaxoSmithKline

Completed

Phase I Study of GSK2982772 in Japanese Healthy Male Participants

Autoimmune Diseases

Japan
National Center for Global Health and Medicine,...
Ministry of Health, Labour and Welfare, Japan

Completed

Comparing Continuing Tenofovir, Emtricitabine (or Lamivudine) Plus Lopinavir and Switching to Raltegravir Plus Darunavir (SPARE)

HIV Infections

Japan
Takeda

Active, not recruiting

A Study to Evaluate the Long-term Safety of TAK-771 in Japanese Primary Immunodeficiency Disease (PID) Participants

Primary Immunodeficiency Diseases (PID)

Japan
Pfizer

Completed

A Study To Compare The Amount Of Premarin Components That Is Absorbed Into The Blood Of Japanese Healthy Postmenopausal Women Following Oral Administration Of Two Different Tablets Of Premarin Under Fast and Fed Conditions.

Menopause | Vaginitis | Metrorrhagia | Primary Ovarian Insufficiency

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

Exploratory Study of TAC-302 in Detrusor Underactivity Patients With Overactive Bladder.

Overactive Bladder | Detrusor Underactivity

Japan
National Center for Global Health and Medicine,...

Completed

Safety Study of Maraviroc's Effect on Human Osteoclasts (MVC-Bone)

HIV Infections | AIDS

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

Exploratory Trial of TAS-303 in Female Patients With Stress Urinary Incontinence

Stress Urinary Incontinence

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

A Study of TAS-303 in Female Patients With Stress Urinary Incontinence

Stress Urinary Incontinence

Japan
Taisho Pharmaceutical Co., Ltd.
Nagoya University

Completed

Development and Validation of a Driving Simulator for Evaluating the Residual Effects of Drugs on Driving Performance - Sensitivity Analysis Using Zopiclone as a Positive Control

Healthy Participants

Japan
Bayer

Recruiting

A Study to Learn More About How Safe Darolutamide is Under Real-world Conditions in Participants With Metastatic Hormone-Sensitive Prostate Cancer (DADOX)

Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Japan
International Medical Center of Japan
Ministry of Health, Labour and Welfare, Japan

Completed

Comparing the Effectiveness Between Ritonavir Boosted Atazanavir and Efavirenz for the First HIV Treatment

HIV Infection

Japan
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Pharmacokinetics of Raltegravir (MK-0518) in Healthy Japanese Male Participants (MK-0518-851)

Human Immunodeficiency Virus (HIV) Infection

Japan
CSL Behring

Completed

Multicenter Study of Long-Term Clinical Outcomes of Subcutaneous Immune Globulin IgPro20 in Subjects With Primary Immunodeficiency (Japan Study)

Primary Immune Deficiency

Japan
Takeda

Recruiting

A Survey of Lanadelumab in Participants With Hereditary Angioedema

Hereditary Angioedema (HAE)

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Long-term Safety and Tolerability of Subcutaneous Administration of TEV-48125 for the Preventive Treatment of Migraine

Migraine

Japan
Kyowa Kirin Co., Ltd.

Completed

Phase 3 Study of KHK7580 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Primary Hyperparathyroidism

Primary Hyperparathyroidism | Parathyroid Carcinoma

Japan
Kyowa Kirin Co., Ltd.

Completed

An Intra-individual Titration Study of KRN1493 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Intractable Primary Hyperparathyroidism

Primary Hyperparathyroidism | Parathyroid Carcinoma | Hypercalcemia

Japan
Otsuka Pharmaceutical Co., Ltd.

Recruiting

Specified Drug Use Survey on AJOVY Subcutaneous Injection for Long-term Use

Migraine Disorders

Japan
Gunma University

Completed

Diagnostic Usefulness of Fluorine-18-α-Methyltyrosine PET in Combination With 18F-FDG in Sarcoidosis Patient

Sarcoidosis

Japan
CSL Behring

Completed

Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)

Primary Immune Deficiency

Japan
Ono Pharmaceutical Co. Ltd
Kyorin Pharmaceutical Co.,Ltd

Completed

Long-term Safety and Efficacy of Imidafenacin in Patients With Overactive Bladder

Overactive Bladder

Japan

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