Clinical Trials on Primary Rectal Cancer in United States

Total 68192 results

Stanford University
Caring for Carcinoid Foundation; GI Cancer Research Gift Fund

Withdrawn

Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers

Gastrointestinal Neoplasms | Pancreatic Cancer | Anal Cancer | Colon/Rectal Cancer | Hepatobiliary Cancers | Gastric (Stomach) Cancer | Gynecologic Cancers | Gastro-Esophageal(GE) Junction Cancer | Gynecologic Cancers Cervical Cancer | Gastrointenstinal Stromal Tumor (GIST) | Colon/Rectal Cancer Colon Cancer and other conditions

United States
Stanford University

Terminated

Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors

Head and Neck Cancer | Colorectal Neoplasms | Lung Cancer | Colon Cancer | Colonic Neoplasms | Head and Neck Cancers | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer | Colon/Rectal Cancer Colon Cancer | Colon/Rectal Cancer Rectal Cancer | Colon/Rectal Cancer Anal Cancer | Head and Neck Cancers Lip | Head... and other conditions

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage IV Pancreatic... and other conditions

United States
National Cancer Institute (NCI)

Completed

Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Adenocarcinoma of the Rectum

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Rectal Adenocarcinoma | Recurrent Rectal Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Stage IVA Rectal Cancer AJCC v8 | Stage IVB Rectal Cancer AJCC v8 | Stage IVC Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage... and other conditions

United States
Washington University School of Medicine

Completed

Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum (NORMAL-R)

Rectal Cancer | Cancer of Rectum | Cancer of the Rectum | Neoplasm, Rectum | Rectum Cancer | Rectum Neoplasms | Adenocarcinoma of the Rectum

United States
Northwestern University
Bristol-Myers Squibb; American Cancer Society, Inc.; Melanoma Research Foundation...

Completed

Development of ImmunOncoTool (ACS-MRA)

Cancer | Cancer, Treatment-Related

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Programs to Support You During Chemotherapy (Pro-You) (Pro-You)

Fatigue | Depressive Symptoms | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Psychosocial Effects of Cancer and Its Treatment | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon... and other conditions

United States
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer

United States
Branimir Sikic
AstraZeneca

Completed

Phase I Vandetanib Plus Capecitabine, Oxaliplatin and Bevacizumab for Metastatic Colorectal Cancer

Colorectal Neoplasms | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer

United States
Ohio State University Comprehensive Cancer Center

Completed

2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer

Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IV A Bladder Cancer | Stage IV A Rectal Cancer | Stage IV B Colon Cancer | Stage IV B Rectal Cancer

United States
Memorial Sloan Kettering Cancer Center
M.D. Anderson Cancer Center; Albert Einstein College of Medicine; Icahn School... and other collaborators

Active, not recruiting

The Sexual Health of Rectal Cancer Patients

Rectal Cancer | Rectum

United States
National Cancer Institute (NCI)

Completed

A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
National Cancer Institute (NCI)

Completed

Oxaliplatin, Fluorouracil, and External-Beam Radiation Therapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum

Adenocarcinoma of the Rectum | Stage II Rectal Cancer | Stage III Rectal Cancer

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Southwest Oncology Group

Completed

Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Terminated

Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal Cancer Undergoing Chemotherapy

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
University of Utah

Not yet recruiting

Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Metastatic Colorectal Cancer (FACE)

Metastatic Colon Cancer | Metastatic Rectum Cancer

United States
MapKure, LLC

Recruiting

A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Colorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

United States
Stanford University
Susan G. Komen Breast Cancer Foundation; Breast Cancer Research Foundation

Recruiting

Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples

Breast Cancer | Ovarian Cancer | Gynecologic Cancers | Ovarian/Peritoneal/Fallopian Cancer

United States
Johns Hopkins Bloomberg School of Public Health
Centers for Medicare and Medicaid Services

Completed

Partnership for Healthy Seniors

Breast Cancer | Prostate Cancer | Cervix Cancer | Colon Cancer | Rectum Cancer

United States
National Cancer Institute (NCI)

Completed

Bevacizumab, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer

Adenocarcinoma of the Rectum | Stage II Rectal Cancer | Stage III Rectal Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Case Comprehensive Cancer Center

Completed

PET-MRI in Diagnosing Patients With Colon or Rectal Cancer

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer and other conditions

United States
Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
National Cancer Institute (NCI)

Completed

Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery

Adenocarcinoma of the Rectum | Stage I Colon Cancer | Stage I Rectal Cancer | Stage II Colon Cancer | Stage II Rectal Cancer | Stage III Colon Cancer | Stage III Rectal Cancer | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

Ovarian Endometrioid Adenocarcinoma | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Recurrent Breast Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer

Pancreatic Adenocarcinoma | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Pancreatic Ductal Adenocarcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Rectal Adenocarcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon... and other conditions

United States
OHSU Knight Cancer Institute
Natera, Inc.

Recruiting

Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage IIA Rectal Cancer AJCC v8 | Stage IIB Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Stage IIC Rectal Cancer AJCC v8

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage IIA Rectal Cancer AJCC v8 | Stage IIB Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Stage IIC Rectal Cancer AJCC v8

United States
Northwestern University

Completed

Oncotool for Cancer Medications

Cancer | Communication | Medication Adherence | Cancer, Treatment-Related | Tyrosine Kinase Inhibitor

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery

Mucinous Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI); American Cancer Society (ACS) National Office

Completed

Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers

Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage III Renal Cell Cancer | Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional... and other conditions

United States
Rutgers, The State University of New Jersey
University of California, Los Angeles; University of New Mexico

Active, not recruiting

Project HERO: Health Empowerment & Recovery Outcomes (HERO)

Kidney Cancer | Small Intestine Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Colon Cancer | Thyroid Cancer | Rectum Cancer | Soft Tissue Cancer

United States
RefleXion Medical

Recruiting

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System (PREMIER)

Cancer | Cancer, Gastrointestinal | Cancer Central Nervous System | Cancer Thoracic | Cancer Gynecologic | Cancer, Genito-Urinary | Cancers Lymphatic | Cancer Head and Neck

United States
University of Virginia
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Ovarian Epithelial or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
Taris Biomedical LLC
Bristol-Myers Squibb

Terminated

Safety and Tolerability of TAR-200 and Nivolumab in Subjects With Muscle-Invasive Bladder Cancer

Bladder Cancer TNM Staging Primary Tumor (T) T2 | Bladder Cancer TNM Staging Primary Tumor (T) T2A | Bladder Cancer TNM Staging Primary Tumor (T) T2B | Bladder Cancer TNM Staging Primary Tumor (T) T3 | Bladder Cancer TNM Staging Primary Tumor (T) T3A | Bladder Cancer TNM Staging Primary Tumor... and other conditions

United States
National Cancer Institute (NCI)

Completed

SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Stage III Colon Cancer | Stage III Rectal Cancer | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Completed

Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Adenocarcinoma of the Rectum | Stage III Colon Cancer | Stage III Rectal Cancer | Adenocarcinoma of the Colon

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | HPV Cancers | Vulvar, Vaginal, Penile, Rectal Cancer

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Mindfulness-Based Exercise Video in Educating Hispanic/Latino Patients With Colorectal Cancer and Their Caregivers

Depression | Fatigue | Rectal Cancer | Colon Cancer | Anxiety Disorder

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer

Pancreatic Cancer | Rectal Cancer | Colon Cancer | Primary Peritoneal Cavity Cancer | Perioperative/Postoperative Complications

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Effectiveness and Implementation of mPATH-CRC

Cancer | Colorectal Cancer | Colon Cancer | Rectum Cancer

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; Taiho Pharmaceutical Co., Ltd.

Recruiting

TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage IIA Rectal Cancer AJCC v8 | Stage IIB Rectal Cancer AJCC v8

United States
University of California, San Francisco
Patient-Centered Outcomes Research Institute; Pierre's Birthday Fund

Completed

Acupressure for Children in Treatment for a Childhood Cancer (ACT-CC)

Treatment-Related Cancer

United States
Johns Hopkins Bloomberg School of Public Health
Centers for Medicare and Medicaid Services

Completed

Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial (CPTD)

Breast Cancer | Lung Cancer | Prostate Cancer | Cervix Cancer | Colon Cancer | Rectum Cancer

United States
M.D. Anderson Cancer Center
Bayer; Xencor, Inc.

Withdrawn

Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME)

Colorectal Cancer | Colon Cancer | Rectum Cancer

United States
Washington University School of Medicine

Terminated

PET/MR for Rectal Cancer Treatment Monitoring and Surveillance

Rectal Cancer | Cancer of the Rectum

United States
National Cancer Institute (NCI)

Terminated

Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal...

United States

Clinical Trials on Primary Rectal Cancer in United States

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CROs in Kyrgyzstan

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