Clinical Trials on Primary Sjögren's Syndrome (pSS) in United Kingdom

Total 5072 results

University College, London

Completed

SS-INQ Information Needs Questionnaire in Sjögren's Syndrome (SS-INQ)

Sjögren's Syndrome

United Kingdom
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

United States, Hungary, Germany, Switzerland, United Kingdom
UCB Celltech
PRA Health Sciences

Terminated

UCB Proof of Concept Study in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

France, Italy, Spain, Sweden, United Kingdom
MedImmune LLC
Amgen

Completed

A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

United States, Sweden, France, United Kingdom
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Completed

Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients

Primary Sjögren's Syndrome

United States, France, United Kingdom, Australia, Germany, Hungary, Spain
Amgen

Recruiting

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Sjögren's Syndrome (SS)

United States
Bristol-Myers Squibb

Terminated

BMS-986325 in Healthy Participants and Participants With Primary Sjögren's Syndrome

Healthy Participants | Primary Sjögren's Syndrome

Germany, United States
National Institute of Allergy and Infectious Diseases...
Biogen; Autoimmunity Centers of Excellence

Terminated

Baminercept, a Lymphotoxin-Beta Receptor Fusion Protein, for Treatment of Sjögren's Syndrome

Primary Sjögren's Syndrome

United States
Incyte Corporation

Completed

A Study of INCB050465 in Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

United States
University of Rochester

Completed

Pilot Trial of Ustekinumab for Primary Sjögren's Syndrome

Primary Sjögren Syndrome

United States
National Institute of Dental and Craniofacial Research...

Terminated

Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome Subjects

Xerostomia | Sjögren's Syndrome

United States
Biogen

Completed

A Longitudinal, Observational Biomarker Study in Participants With Primary Sjogren's Syndrome

Healthy | Sjögren's Syndrome | Sicca Syndrome

United States
University College, London
Cambridge University Hospitals NHS Foundation Trust; Sheffield Teaching Hospitals... and other collaborators

Active, not recruiting

Paediatric Sjögren Syndrome Cohort Study and Repository (PaedSSCoRe) (PaedSSCoRe)

Sjogren's Syndrome Childhood-onset

United Kingdom, Ireland
University of California, Los Angeles
University Medical Center Groningen; Oklahoma Medical Research Foundation

Completed

Salivary Biomarkers for Sjögren's Syndrome Detection

Sjögren's Syndrome

United States
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sjögren's Syndrome (SS)

Sjögren's Syndrome

United States, France, Italy, Hungary, Poland, Argentina, India, Korea, Republic of, Mexico, Peru, Taiwan, United Kingdom
Bristol-Myers Squibb

Completed

Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Autoimmune Disorder | Primary Sjögren's Syndrome

United States, Argentina, Belgium, France, Germany, Mexico, Poland, Spain, Netherlands, United Kingdom
The Cleveland Clinic
Bristol-Myers Squibb

Withdrawn

Abatacept for Patients With Inflammatory Arthritis Associated With Sjögren's Syndrome: an Open-Label Phase II Study

Rheumatoid Arthritis | Inflammatory Arthritis | Primary Sjogren's Syndrome | Secondary Sjogren's Syndrome

United States
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome (POETYK SjS-1)

Sjögren's Syndrome

United States, Australia, Germany, Austria, China, Korea, Republic of, Puerto Rico, Poland, Japan, Canada, Hungary, Spain, Argentina, Chile, Denmark, France, Italy, Mexico, Peru, Taiwan, Netherlands, Belgium, Brazil, Colombia, United Kingdom and more
Eli Lilly and Company

Completed

A Study of LY3090106 in Participants With Sjögren's Syndrome (SS)

Sjögren's Syndrome

United States, Bulgaria, Georgia, Romania
Sanofi

Completed

Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS) (phaethuSA)

Sjogren's Syndrome | Sjögren's Syndrome

Belgium, Taiwan, Korea, Republic of, United States, Argentina, Canada, Chile, France, Germany, Hungary, Mexico, Spain
Novartis Pharmaceuticals

Terminated

A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's Syndrome (LOUiSSe)

Sjögren Syndrome

Spain, United States, Belgium, Hungary, Germany, Switzerland, Australia, Denmark, China, Taiwan, United Kingdom, Bulgaria
Bristol-Myers Squibb

Terminated

Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome

Sjögren's Syndrome

Australia, United States, Italy, Mexico, Colombia, Peru, Puerto Rico, South Africa, Chile, Poland, Russian Federation
Matthew C. Baker

Withdrawn

BAFF/IL-17 Bispecific Antibody Treatment in Subjects With Primary Sjogren's Syndrome (BAFF/IL-17)

Primary Sjogren's Syndrome

United States
Novartis Pharmaceuticals

Recruiting

A Randomized, Double-blind 2-arm NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome. (NEPTUNUS-Ext)

Sjogrens Syndrome

Spain, Austria, Japan, Poland, Germany, Turkey, Hungary, Israel, Italy, France, Portugal, Taiwan, Australia, Slovakia, United Kingdom, Brazil, Guatemala, Czechia, Bulgaria, United States, Canada, Argentina, Romania
Bedford Hospital NHS Trust
Moorfields Eye Hospital NHS Foundation Trust; University Hospitals Bristol... and other collaborators

Unknown

Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood (FAB)

Dry Eyes | Sjogren's Disease With Dry Eyes | Persistent Corneal Epithelial Defects | Chronic Corneal Ulcers

United Kingdom
Novartis Pharmaceuticals

Completed

Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome (TWINSS)

Sjögren Syndrome

United States, United Kingdom, Netherlands, Australia, Austria, Israel, France, Germany, Greece, Hungary, Italy, Korea, Republic of, Japan, Portugal, Russian Federation, Turkey, Canada, Colombia, Romania, Argentina, Chile, Brazil, S...
GlaxoSmithKline
Adelphi Real World

Completed

Adelphi Primary Sjogren's Syndrome (pSS) Disease Specific Programme (DSP)

Sjogren's Syndrome

United Kingdom
GlaxoSmithKline

Withdrawn

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Proof of Mechanism of GSK2618960 in Primary Sjögren's Syndrome (pSS)

Autoimmune Diseases

United Kingdom
Resolve Therapeutics
Newcastle-upon-Tyne Hospitals NHS Trust; University Hospital Birmingham

Completed

A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome (RSLV-132)

Sjogren's Syndrome

United Kingdom
GlaxoSmithKline
Quintiles, Inc.

Completed

A PH I Pilot Imaging Study to Evaluate Molecular Imaging Methods in HVs and pSS Pts

Autoimmune Diseases

United Kingdom
TearSolutions, Inc.

Completed

Lacripep™ in Subjects With Dry Eye Associated With Primary Sjögren's Syndrome

Dry Eye | Primary Sjögren Syndrome

United States
Northumbria University
Newcastle University; Versus Arthritis; Teesside University

Unknown

Pilot Feasibility Study of a Sjögren's Syndrome Self-management App

Sjogren's Syndrome

United Kingdom
FibroGen
AstraZeneca; Astellas Pharma Inc

Terminated

Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden

Primary MDS (Very Low, Low or Intermediate IPSS-R With <5% Blasts)

United States, Australia, Belgium, Germany, Israel, Italy, Korea, Republic of, Russian Federation, Spain, United Kingdom, France, Turkey, Canada, Denmark, India, Poland
University of Nebraska

Completed

Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers (SLS)

Sjogren-Larsson Syndrome (SLS)

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of VAY736 in Patients With Primary Sjogren's Syndrome (pSS)

Primary Sjogren Syndrome

United States, Belgium, Italy, Austria, Israel, France, Germany, Hungary, Netherlands, United Kingdom, Japan, Portugal, Argentina, Spain, Taiwan, Russian Federation, Romania, Chile, Poland
Aldeyra Therapeutics, Inc.

Completed

RESET Trial - Part 1 - A Phase 3 Trial in Subjects With Sjögren-Larsson Syndrome (SLS)

Sjogren-Larsson Syndrome

United States
Bristol-Myers Squibb

Completed

A Study to Assess the Efficacy and Safety of Abatacept in Adults With Active Primary Sjögrens Syndrome

Sjogrens Disease

United States, France, Italy, Sweden, Japan, Australia, Mexico, Argentina, Brazil, Korea, Republic of, Czechia, Puerto Rico, Germany
Parion Sciences

Completed

A Safety and Efficacy Study of 552-02 in Subjects With Dry Mouth Associated With Sjogren's Syndrome

Xerostomia | Dry Mouth Associated With Sjogren's Syndrome

United States
John Carroll University
University Hospital Southampton NHS Foundation Trust

Active, not recruiting

Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients

PTEN Hamartoma Tumor Syndrome

United States, United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Azacitidine and Pembrolizumab in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | IPSS Risk Category Intermediate-1

United States
Aldeyra Therapeutics, Inc.

Completed

A Study of Topical NS2 Cream to Treat Ichthyosis in Sjögren-Larsson Syndrome (SLS)

Sjögren-Larsson Syndrome

United States
University of Rochester
Bausch & Lomb Incorporated

Completed

Evaluation of Ocular Surface Inflammatory Mediators Effected by Lotemax

Sjogren's Disease

United States
Mirum Pharmaceuticals, Inc.

Completed

Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing Cholangitis (CAMEO)

Primary Sclerosing Cholangitis (PSC)

United States, United Kingdom, Canada
University of Rochester

Completed

Multi-Colored Placido Disk Viability

Healthy | Dry Eye | Sjogren's Disease

United States
Sylentis, S.A.

Completed

Tivanisiran for Dry Eye in Subjects With Sjögren's Syndrome

Dry Eye Disease | Sjögren Syndrome

United States, Spain
University of Pennsylvania
Forest Laboratories

Terminated

Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study

PMS

United States
Kirby Institute

Completed

Pharmacokinetics of Lopinavir/Ritonavir at Three Different Doses. (ENCORE3)

Acquired Immunodeficiency Syndrome

United Kingdom
University College, London
Medical Research Council

Recruiting

Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation (ToTem)

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myeloma | Graft Vs Host Disease | Severe Aplastic Anemia | Primary Immune Deficiency

United Kingdom
Case Western Reserve University

Completed

e-Mobile Tablet for People With Chronic Conditions

Multiple Sclerosis | Osteoarthritis | Parkinson's Disease | Fibromyalgia | Sjögren's Syndrome

United States
Genethon
Institute of Child Health; Great Ormond Street Hospital for Children NHS Foundation...

Completed

Gene Therapy for Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

United Kingdom

Clinical Trials on Primary Sjögren's Syndrome (pSS) in United Kingdom

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