Clinical Trials on Pro-inflammatory Activity

Total 10209 results

Atara Biotherapeutics
Merck Sharp & Dohme LLC

Terminated

Tabelecleucel in Combination With Pembrolizumab in Subjects With Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)

Nasopharyngeal Carcinoma | Nasopharyngeal Neoplasms | Epstein-Barr Virus Infections | Epstein-Barr Viraemia | Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)

United States
AbbVie

Completed

Impact of AbbVie Care Patient Support Program on Clinical, Health Economic and Patient Reported Outcomes, in Crohn's Disease, Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Psoriasis and Axial Spondyloarthritis, in the Portuguese National Health Service (IMPROVE)

Psoriasis | Crohn's Disease | Psoriatic Arthritis | Rheumatoid Arthritis (RA) | Non-radiographic Axial Spondyloarthritis | Ulcerative Colitis (UC) | Ankylosing Spondylitis (AS)

Portugal
Fakultas Kedokteran Universitas Indonesia

Unknown

Zinc Supplementation on Very Low Birth Weight Infant

Enterocolitis, Necrotizing | Retinopathy of Prematurity | Bronchopulmonary Dysplasia | Early-Onset Sepses, Neonatal | Small for Gestational Age Infant | Periventricular Haemorrhage Neonatal
University of Rhode Island
National Institute of Nursing Research (NINR); Thrasher Research Fund

Completed

Effects of Delayed Cord Clamping in Very Low Birth Weight Infants

Necrotizing Enterocolitis | Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Motor Skills Disorders | Late Onset Neonatal Sepsis

United States
Karolinska Institutet
The Swedish Research Council; Swedish University of Agricultural Sciences; The... and other collaborators

Completed

Drinking Water PFAS, Pregnancy Outcome and Maternal Morbidity

Birth Weight | Preeclampsia | Diabetes, Gestational | Hypertension in Pregnancy | Small for Gestational Age at Delivery | Congenital Malformation | Large for Gestational Age at Delivery (Macrosomia)
The Cooper Health System

Unknown

Association of Hypertensive Disorder of Pregnancy With Sleep-disordered Breathing.

Sleep-disordered Breathing | Hypertensive Disorder of Pregnancy

United States
Extremity Medical

Recruiting

The KinematX Midcarpal Total Wrist Arthroplasty Registry

Osteoarthritis | Inflammatory Arthritis | Carpal Tunnel Syndrome (CTS) | Post Traumatic Arthritis | Scapholunate Advanced Collapse (SLAC) | Scapholunate Crystalline Advanced Collapse (SCAC) | Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC) | Kienbock's Disease of Adults | Radial Malunion | Ulnar Translocation and other conditions

United States
Paul Szabolcs

Recruiting

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC (PRO-RIC)

Congenital Bone Marrow Failure Syndromes | Inflammatory Conditions | Primary Immunodeficiency (PID) | Inherited Metabolic Disorders (IMD) | Hereditary Anemias

United States
Charite University, Berlin, Germany
Wyeth is now a wholly owned subsidiary of Pfizer; UCB Pharma; Novartis; AbbVie; German... and other collaborators

Recruiting

German Spondyloarthritis Inception Cohort (GESPIC)

Crohn Disease (CD) | Ulcerative Colitis (UC) | Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA) | Non-radiographic Axial Spondyloarthritis (Nr-axSpA) | Axial Psoriatic Arthritis (axPsA) | Acute Anterior Uveitis (AAU)

Germany
Masonic Cancer Center, University of Minnesota

Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Cytokine Release Syndrome | Immune and Microbial Reconstitution | Systemic Viral Infection | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease | Recurrent Malignancy | Allogenic Related Donors | Cell Therapy/Immunotherapy Patients

United States
University of Eastern Finland

Active, not recruiting

Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)

Depression | Liver Diseases | Cardiovascular Diseases | Diabetes | Cancer | Atherosclerosis | Death | Metabolic Syndrome | Chronic Disease | Cognitive Decline | Infection | Pain, Chronic | Inflammatory Disease
University of Texas Southwestern Medical Center

Withdrawn

Effects of Growth Hormone in Chronically Ill Children

HIV Infections | Cerebral Palsy | Crohn Disease | Hurler Syndrome | Juvenile Rheumatoid Arthritis

United States
University of Colorado, Denver

Completed

Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease (FAB)

Cardiovascular Diseases | Diabetes | Preterm Birth | Overweight and Obesity | Preeclampsia | Gestational Diabetes | Small for Gestational Age at Delivery | Gestational Hypertension

United States
University Hospital, Bordeaux

Recruiting

Study of Gynecological Follow-up of Patients With Autoimmune Disease or Inflammatory Rheumatism (MARIGYN)

Arthritis, Rheumatoid | Lupus Erythematosus, Systemic | Scleroderma, Systemic | Sjogren's Syndrome | Spondylitis, Ankylosing | Mixed Connective Tissue Disease

France
NYU Langone Health
Daxor Corporation

Completed

Blood Volume Assessment in COVID-19 and Bacterial Sepsis (BVAC19)

Covid19 | Bacterial Infections | Acute Respiratory Distress Syndrome | Bacterial Sepsis

United States
Rigshospitalet, Denmark
Statens Serum Institut

Completed

Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection

Neonatal Infection | Viral Infection | Neonatal Sepsis | Neonatal Death | Herpes Simplex Virus Infection | Newborn; Infection | Neonatal Herpes Simplex Infection | Neonatal HSV Infection

Denmark
Institut de cancérologie Strasbourg Europe
LEAF4Life, Inc.

Completed

A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to COVID-19, Sepsis or Other Causes

Acute Respiratory Distress Syndrome | COVID19, Sepsis or Other Causes

France
Loma Linda University

Withdrawn

Tazemetostat for the Treatment of Moderate to Severe COVID-19 Infection (IST)

Cytokine Release Syndrome | COVID-19 Acute Respiratory Distress Syndrome
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Malignant Neoplasm | Bacterial Infection | Myeloid Neoplasm | Benign Neoplasm | Methicillin-Resistant Staphylococcus Aureus Infection

United States, Canada, Puerto Rico
Hospital Clinic of Barcelona

Unknown

Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients (COVID-DEX)

Inflammation | Acute Respiratory Distress Syndrome | Dexmedetomidine | Cytokine Storm | Delirium, Emergence
Dr John Kimoff
Canadian Institutes of Health Research (CIHR); ResMed Canada Inc.

Completed

Positive Airway Pressure Treatment of Obstructive Sleep-disordered Breathing in Hypertensive Disorders of Pregnancy

Sleep Apnea, Obstructive | Hypertensive Disorder of Pregnancy

Canada
Inovio Pharmaceuticals

Completed

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

Human Papillomavirus (HPV) | Vulvar Dysplasia | Vulvar Intraepithelial Neoplasia (VIN) | Vulvar High Grade Squamous Intraepithelial Lesion (HSIL) | VIN2 | VIN3 | Pre-cancerous Lesions of the Vulva

United States
Progenity, Inc.

Unknown

Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women

Hypertension | Renal Insufficiency | Thrombocytopenia | Headache | Pre-Eclampsia | Pulmonary Edema | Visual Impairment | Impaired Liver Function | Proteinuria in Pregnancy

United States
University College, London

Unknown

TTP and aHUS in Complicated Pregnancies

Thrombotic Microangiopathies | Thrombotic Thrombocytopenic Purpura | Thrombocytopenia | Pre-Eclampsia | HELLP Syndrome | Stillbirth | Atypical Hemolytic Uremic Syndrome | IUGR

United Kingdom
Vilnius University
Kaunas University of Technology

Recruiting

Triggers and Risk Factors for Recurrence of Atrial Arrhythmias With the Use of Long-term Monitoring (TriggersAF)

Alcohol Drinking | Sleep Disorder | Stress | Atrial Fibrillation | Sleep Apnea | Atrial Flutter | Arterial Hypertension | Physical Inactivity | Atrial Tachycardia | Atrial Arrhythmia | Caffeine Dependence | Premature Atrial Contractions | Overexertion

Lithuania
Umraniye Education and Research Hospital

Recruiting

Serum Vasohibin, Cardiotrophin, Endocan & Perinatal Outcomes

Preterm Birth | Fetal Growth Retardation | Preeclampsia | Gestational Diabetes | Gestational Hypertension

Turkey
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
University Hospital Muenster

Recruiting

Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.

Sepsis | Pre-Eclampsia | Adiposity | Microscopic Polyangiitis | Granulomatosis With Polyangiitis | SIRS | Procalcitonin

Germany
Assistance Publique - Hôpitaux de Paris

Completed

Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm Newborn (ANGIODYS)

Preterm Birth | Bronchopulmonary Dysplasia | Intra-uterine Growth Restriction | Maternal Preeclampsia

France
Heidelberg University
University Hospital Heidelberg

Terminated

TPF Followed by Cetuximab and IMRT Plus Carbon Ion Boost for Locally Advanced Head and Neck Tumors (TPF-C-HIT)

Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN): Oro-, Hypopharyngeal and Laryngeal Cancer

Germany
Assaf-Harofeh Medical Center
Meir Medical Center

Unknown

The Association Between High Risk Pregnancy and Sleep-disordered Breathing

Preeclampsia | Gestational Diabetes | Premature Labor

Israel
Epic Research & Diagnostics, Inc.

Completed

Prognostic Indicators as Provided by the EPIC ClearView (GBMC)

Coronary Artery Disease | Pneumonia | Hypertension | Diabetes | Irritable Bowel Syndrome | Atrial Fibrillation | Asthma | Renal Failure | Emphysema | Cholecystitis | Cirrhosis | Crohn's Disease | Ulcerative Colitis | Acute Renal Failure | Diverticulitis | Pancreatitis | Bronchitis | Valvular Heart Disease | Inflammatory Bowel Disease and other conditions

United States
Beijing Tiantan Hospital

Recruiting

China National Registry of Neuro-Inflammatory Diseases (CNRID)

Multiple Sclerosis | Clinically Isolated Syndrome | Acute Disseminated Encephalomyelitis | NMO Spectrum Disorder | CNS Demyelinating Autoimmune Diseases | Primay Angiitis of the Central Nervous System | Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy

China
University College, London
Ministry of Health and Child Welfare, Zimbabwe; Biomedical Research and Training... and other collaborators

Recruiting

Evaluating the NeoTree in Malawi and Zimbabwe

Neonatal Encephalopathy | Prematurity | Neonatal Seizure | Neonatal Jaundice | Neonatal Sepsis | Neonatal Death | Neonatal Respiratory Failure | Neonatal Hypoglycemia | Neonatal Disorder | Neonatal Hypothermia

Zimbabwe, Malawi
University Hospital, Gentofte, Copenhagen

Active, not recruiting

The Relationship Between Inflammatory ARTritis and CArdiac DIseAse (ARTCADIA)

Myocardial Infarction | Heart Failure | Stroke | Rheumatoid Arthritis | Ischemic Heart Disease | Inflammatory Arthritis | Heart Failure, Diastolic | Valvular Heart Disease | Heart Failure, Systolic | Spondylitis, Ankylosing | Cardiac Disease | Spondyloarthritis | Axial Spondyloarthritis | Myocardial Dysfunction | Left...

Denmark
Alexandria University
Science and Technology Development Fund (STDF), ,Egypt

Completed

Safety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University Hospital

Pulmonary Fibrosis | Cytokine Release Syndrome | COVID-19 Acute Respiratory Distress Syndrome

Egypt
University of Florida
Society for Pediatric Dermatology; Eunice Kennedy Shriver National Institute...

Completed

Antibiotic "Dysbiosis" in Preterm Infants

Bacteremia | Enterocolitis, Necrotizing | Intraventricular Hemorrhage | Chronic Lung Disease | Bronchopulmonary Dysplasia | Periventricular Leukomalacia | Ileal Perforation

United States
Princess Anna Mazowiecka Hospital, Warsaw, Poland
Medical University of Warsaw

Not yet recruiting

The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. (HIDVID)

Nephrolithiasis | Vitamin D Deficiency | Metabolic Bone Disease | Osteopenia of Prematurity | Late-Onset Neonatal Sepsis

Poland
Pfizer

Completed

Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults

Bacteremia | Urinary Tract Infection | Intra-abdominal Infection | Hospital Acquired Pneumonia | Acute Pyelonephritis | Ventilator-associated Pneumonia

China
Dr Caeymaex Laurence
Ministry of Health, France; Paris 12 Val de Marne University

Completed

SEPREVEN: a Stepped-wedge Randomised Controlled Trial (SEPREVEN)

Nosocomial Pneumonia | Extravasation Injury | Skin Lesion | Intubation Complication | Intensive Care Units, Neonatal | Misadventures to Patients During Surgical and Medical Care | Catheter-related Bloodstream Infection (CRBSI) Nos | Quality of Healthcare | Ventilator Adverse Event | Immature Newborn | Nasal... and other conditions

France
University Hospital, Montpellier

Unknown

Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic Treatments

Osteoarthritis | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Spondylitis | Sjogren's Syndrome | Gout | Scleroderma | Spinal Disease | Chondrocalcinosis

France
Vitio Medical S.L.
Hospital Universitario de Navarra; NAVARRABIOMED

Completed

Continuous Temperature Telemonitoring of Patients With COVID-19 and Other Infectious Diseases in Hospital at Home Using Viture (Viture)

COVID-19 | Infectious Disease | Bacteremia | Cellulitis | Respiratory Infection | Tract Infection, Urinary

Spain
Universitaire Ziekenhuizen KU Leuven

Completed

Registry With Information About Colitis Ulcerosa and Familial Adenomatous Polyposis Patients (KOPOF)

Adenomatous Polyposis Coli | Colitis,Ulcerative | Reservoir, Ileoanal

Belgium
Achaogen, Inc.
Department of Health and Human Services

Completed

A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) (CARE)

Bloodstream Infections (BSI) Due to CRE | Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE | Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE | Complicated Urinary Tract Infection (cUTI) Due to CRE | Acute Pyelonephritis (AP) Due to CRE
Shaare Zedek Medical Center

Completed

Procalcitonin Level and Kinetics in Children With Bacterial Infections

Bacterial Infections | Bacteremia | Cellulitis | Urinary Tract Infection | Meningitis | Osteomyelitis | Septic Arthritis | Mastoiditis | Lobar Pneumonia

Israel
IRCCS San Raffaele
Università Vita-Salute San Raffaele

Recruiting

Mechanisms of Somatic Mutation and Tumor Initiation in Pre-malignant Kidney Tubule Cells (SoMuKT)

Carcinoma, Renal Cell | Von Hippel-Lindau Disease

Italy
Bispebjerg Hospital
The Danish Council for Strategic Research

Completed

D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life (D-tect)

Obesity | Diabetes Mellitus | Cancer | Arthritis | Vitamin D Deficiency | Asthma | Pregnancy Complications | Tooth Diseases | Birth Weight | Pre-Eclampsia | Mental Disorder | Congenital Disorders | Bone Fracture | Birth Disorder

Denmark
Faculty Hospital Kralovske Vinohrady

Completed

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Infections | Multiple Sclerosis | Autoimmune Diseases | Diabetes Mellitus, Type 1 | Rheumatoid Arthritis | Vaccine Reaction | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Down Syndrome | Atopic Dermatitis | Vitiligo | Alopecia Areata | COVID-19 Pandemic | Ankylosing Spondylitis | Lupus Erythematosus and other conditions

Czechia
Mayo Clinic
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Mayo AVC Registry and Biobank

Heart Diseases | Cardiovascular Diseases | Myocarditis | Cardiomyopathies | Ventricular Tachycardia | Cardiovascular Abnormalities | Sarcoidosis | Sudden Cardiac Death | Cardiac Arrhythmia | Cardiac Sarcoidosis | Sudden Cardiac Arrest | Arrhythmogenic Right Ventricular Cardiomyopathy | Arrhythmogenic Right Ventricular... and other conditions

United States, United Kingdom
Hospital Universitario Virgen Macarena
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Enrolling by invitation

Clinical Outcomes in Patients With Infection by Resistant Microorganism

Pneumonia | Staphylococcus Aureus | Urinary Tract Infections | Surgical Site Infection | Escherichia Coli | Bloodstream Infection | Acinetobacter Infections | Pseudomonas Aeruginosa | Skin Infection | Klebsiella Pneumonia | Enterococcus Faecium Infection

Spain

Clinical Trials on Pro-inflammatory Activity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Tunisia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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