Clinical Trials on Progression

Total 1443 results

National Taiwan University Hospital

Completed

Optimal EGFR TKIs Treatment Strategies for Lung Adenocarcinoma Harboring EGFR Exon 19 Deletion Variants

Tumor Progression | EGFR Exon 19 Mutation

Taiwan
National Taiwan University Hospital

Completed

The Role of Protein Tyrosine Kinase 7 (PTK7) in Non-small Cell Lung Cancer

Tumor Progression

Taiwan
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease

Lung Diseases | Disease Progression | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
Bayer

Completed

VICTOR - Avelox® Intravenous (i.v.) in Acute Exacerbations of Chronic Bronchitis (VICTOR)

Chronic Bronchitis | Disease Exacerbation

China
Uskudar University

Completed

Pain Neuroscience Education and Motor Imagery-based Exercise Protocol for Patients With Fibromyalgia

Pain | Fibromyalgia | Psychology Regression

Turkey
Pfizer
Astellas Pharma Inc; Medivation LLC, a wholly owned subsidiary of Pfizer Inc.

Completed

Determine Effect of Enzalutamide (MDV3100) on the Androgen Signaling Pathway in Correlation With the Anti-tumor Effects of Enzalutamide

Metastatic Progressive Castration-resistant Prostate Cancer

United States
University of Trieste

Recruiting

Multiparametric Home Telemonitoring of Patients With Chronic Obstructive Pulmonary Disease Exacerbation

COPD | COPD Exacerbation Acute

Italy
Lebanese University
Hospital Saydet Zgharta University Medical Center

Recruiting

LUSZ Treatment Efficacy in Hospitalized COVID-19 Patients (LUSZ_AVIST)

COVID-19 | Hospitalized COVID-19 Patients

Lebanon
Hospital do Coracao
Boehringer Ingelheim; Centro Rossi, Buenos Aires, Argentina

Recruiting

HypErsensitiVity PneumonITis: DiseAse Progression Characterization (EVITA)

Hypersensitivity Pneumonitis

Argentina, Brazil, Chile
Centre Jean Perrin
Conseil National des Etablissements Thermaux

Active, not recruiting

Support and Post-therapeutic Rehabilitation for Women in Complete Remission of Breast Cancer in a Thermal Environment (PACTHE-VR)

Quality of Life | Remission | Non-Metastatic Breast Carcinoma

France
Oriol Mitja
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la... and other collaborators

Withdrawn

Use of a Combined Regimen of Fluoxetine, Prednisolone and Ivermectin in the Treatment of Mild COVID-19 to Prevent Disease Progression Progression in Papua New Guinea

COVID-19 | SARS-CoV2 Infection
Vertex Pharmaceuticals Incorporated

Completed

A Study to Explore the Impact of Lumacaftor/Ivacaftor on Disease Progression in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del

Cystic Fibrosis

Germany
University Hospital, Montpellier

Terminated

Sevoflurane in Chronic Obstructive Pulmonary Disease Exacerbation (SEVOCOPD)

COPD Exacerbation | Invasive Mechanical Ventilation

France
Asan Medical Center

Completed

Assessment of CMV-specific ELISPOT Assay for Predicting CMV Colitis in Patient With Ulcerative Colitis (ACE-UC)

Ulcerative Colitis | Cytomegalovirus Infections | Disease Exacerbation

Korea, Republic of
Institute of Liver and Biliary Sciences, India

Completed

Effect of Metformin on Disease Progression in Patients With Cryptogenic Cirrhosis (NASH-related Cirrhosis) With Diabetes or Impaired Glucose Tolerance or Insulin Resistance

NASH Related Cirrhosis

India
Copenhagen University Hospital, Hvidovre
University of Copenhagen

Recruiting

Prospective Cohort Study of Disease and Outcomes in Cirrhosis (ProDoc)

Liver Diseases | Decompensated Cirrhosis | Progression | Liver Cirrhosis, Alcoholic

Denmark
University Hospital Tuebingen
Max-Planck-Institute Tuebingen

Unknown

Early Detection of Clinical Deterioration in Patients With COVID-19 Using Machine Learning (COVID-19)

Covid19

Germany
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council; The Hillingdon Hospitals NHS Foundation Trust; West...

Completed

Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?

Respiratory Tract Diseases | Lung Diseases | Disease Progression | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
National Institute of Neurological Disorders and...

Recruiting

Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy

Multiple Sclerosis | Progressive Multifocal Leukoencephalopathy

United States
Beth Israel Deaconess Medical Center
Biogen; National Multiple Sclerosis Society

Completed

JC Virus Reactivation in Multiple Sclerosis (JCV in MS)

Multiple Sclerosis | Progressive Multifocal Leukoencephalopathy

United States
University of Pennsylvania

Completed

Cognitive Impairement In Frontotemporal Dementia

Frontotemporal Degeneration | Multiple System Atrophy | Progressive Supranuclear Palsy

United States
Shengjing Hospital

Recruiting

A Predictive Tool for Predicting Adverse Outcomes in Acute Pulmonary Embolism Patients Using CTPA.

Pulmonary Embolism and Thrombosis | Deterioration, Clinical

China
EpiEndo Pharmaceuticals
CTC Clinical Trial Consultants AB

Completed

Clinical Trial to Assess Effect of Verapamil on Systemic Exposure of EP395 and Effect of EP395 on Systemic Exposure of Midazolam and Digoxin

COPD | Chronic Obstructive Pulmonary Disease Exacerbation

Sweden
Biogen

Active, not recruiting

A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic Mutation (ALSpire)

Amyotrophic Lateral Sclerosis

United States, Netherlands, Italy, Canada
German CLL Study Group
Janssen-Cilag Ltd.

Completed

Ibrutinib in Previously Untreated Binet Stage A Chronic Lymphocytic Leukemia With Risk of Disease Progression (CLL12)

Chronic Lymphocytic Leukemia

Germany
Clene Nanomedicine
Clene Australia Pty Ltd

Completed

Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS) (RESCUE-ALS)

Amyotrophic Lateral Sclerosis

Australia
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Tocilizumab for Severe RP-ILD Secondary to Systemic Diseases

Rapid Progressive Interstitial Lung Diseases

China
Northwestern University
National Institute on Aging (NIA)

Completed

CB3 Pilot (Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia) (CB3 Pilot)

Dementia | Communication | Alzheimer Disease | Primary Progressive Aphasia | Aphasia

United States
University of Miami

Terminated

Transcranial Magnetic Stimulation (TMS) for Primary Progressive Apraxia of Speech (PPAOS)

Apraxia Speech

United States
Centre Hospitalier Universitaire de Besancon
Assistance Publique - Hôpitaux de Paris; Centre Hospitalier Universitaire Dijon

Unknown

tDCS Effect on Cognitive Functions From Patients With Alzheimer's Disease or Progressive Primary Aphasia (ALSTICO)

Alzheimer's Disease | Progressive Primary Aphasia | Early or Mild State

France
Lee's Pharmaceutical Limited

Recruiting

Phase Ib/II Clinical Study of Pexa-Vec (Vaccinia GM CSF / Thymidine Kinase-Deactivated Virus) Combined With Recombinant Whole Human Anti-PD-L1 Monoclonal Antibody (ZKAB001) in Metastatic Melanoma

Local Progression or Metastatic Melanoma With Failed First-line Treatment

China
University Hospital, Lille
H. Lundbeck A/S; FeetMe; France Parkinson Association; Vaincre Parkinson

Recruiting

Markers of Disease Progression and Gait Within the Parkinsonian Population (Gait'N'Park)

Parkinson Disease

France
Karl Landsteiner Institute for Lung Research and...
Klinik Ottakring; University of Vienna; Klinik Floridsdorf; Therme Wien Med (Ambulant...

Completed

Mindfulness-based Interventions in COPD Patients (SPIROMIND)

Chronic Obstructive Pulmonary Disease Exacerbation

Austria
Shengjing Hospital

Active, not recruiting

An Observational Study About Adverse Outcomes in Acute Pulmonary Embolism Patients

Pulmonary Embolism and Thrombosis | Deterioration, Clinical

China
Michael Bau Mortensen

Completed

Treatment of Peritoneal Carcinomatosis With Pressurized IntraPeritoneal Aerosol Chemotherapy - (PIPAC-OPC2)

Quality of Life | Peritoneal Neoplasms | Chemotherapy Effect | Chemotherapeutic Toxicity | Peritoneal Metastases | Peritoneum; Carcinomatosis | Histologic Progression

Denmark
Szeged University

Unknown

Identification of Genetic Factors Determining Disease Course in the New Type of Coronavirus Infection, COVID-19

COVID-19 | Sars-CoV2

Hungary
American University of Beirut Medical Center

Not yet recruiting

The Addition of Inhaled Furosemide to Standard Treatment of COPD Exacerbation (FUROSCOPE)

COPD Exacerbation | Chronic Obstructive Pulmonary Disease Exacerbation
Philip Morris Products S.A.

Recruiting

Effect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects With Chronic Bronchitis Symptoms.

Smoking | Tobacco Use | COPD

United States, Bulgaria, Czechia, Germany, Japan, Romania, Slovakia, United Kingdom
Wim Janssens
Roche Pharma AG; AstraZeneca; European Respiratory Society

Recruiting

The CATALINA Study

Chronic Obstructive Pulmonary Disease Exacerbation

Belgium, Spain, Sweden, Netherlands, France, Germany, Italy, United Kingdom
Clene Nanomedicine

Active, not recruiting

An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS

Amyotrophic Lateral Sclerosis

Australia
Biogen

Terminated

Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB078 Administered to Previously Treated Adults C9ORF72-Associated Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States, Canada, United Kingdom, Netherlands, Switzerland
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Early transfusIon of Convalescent Plasma in Elderly COVID-19 Patients. to Prevent Disease Progression. (LIFESAVER)

Coronavirus Disease 2019 )COVID-19)

Italy
Port Said University

Unknown

Predictors of COVID-19 Infection and Disease Progression (Portsaiduni)

Positive COVID-19 by PCR

Egypt
Institute of Tropical Medicine, Belgium
University Hospital, Antwerp; Sihanouk Hospital Center of HOPE

Terminated

Monitoring Liver Disease Progression in Hepatitis C/HIV Co-infected Patients With No-to-moderate Fibrosis, in Phnom Penh, Cambodia (HCV-Monitoring)

Hepatitis C | HIV

Cambodia
Zealand University Hospital
Rigshospitalet, Denmark

Unknown

Non-expensive and Widely Available Tests as Diagnostic Tools in Dementia and Their Ability to Predict Disease Progression (DEMPROG)

Mild Cognitive Impairment | Alzheimers Disease

Denmark
University Hospital Tuebingen

Active, not recruiting

Autologous Stem Cell Transplantation for Progressive Systemic Sclerosis (AST-MOMA)

Scleroderma | Autologous Stem Cell Transplantation | Cardiac Involvement

Germany
Centre Hospitalier Universitaire de Nice

Recruiting

An 18-month Prospective Natural History Study to Gain Insight Into FSHD2 Pathophysiology and Disease Progression (INSIGHT FSHD2)

Facioscapulohumeral Muscular Dystrophy Type 2

France, Italy, Spain
The Third Xiangya Hospital of Central South University

Not yet recruiting

TUPKRP Combined With MAB Therapy for LUTS/PCa

Quality of Life | Lower Urinary Tract Symptoms | Advanced Prostate Cancer | Overall Survival | Progression of Prostate Cancer
Memorial Sloan Kettering Cancer Center
University of Pittsburgh; Ohio State University

Recruiting

Genomic Predictors of Papillary Microcarcinoma Disease Progression

Papillary Microcarcinoma

United States
McGill University Health Centre/Research Institute...

Completed

Wearable Devices in the Recovery Phase of Acute Exacerbations of COPD (AECOPDs)

Chronic Obstructive Pulmonary Disease | Chronic Obstructive Pulmonary Disease Exacerbation

Canada

Clinical Trials on Progression

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