Identification of Genetic Factors Determining Disease Course in the New Type of Coronavirus Infection, COVID-19

June 9, 2020 updated by: Szeged University

Identification of Genetic Factors Determining Disease Course and Preparation of Pharmacogenetic Applications in the New Type of Coronavirus Infection, COVID-19

The study aims to identify environmental factors and genetic (gene mutation and gene expression) changes, which influencing the course of the disease the new type of coronavirus infection COVID-19 in patients nationwide in a multicenter study.

At first in the study will be performed 200 patients, selected for a homogeneous groups on the basis of the patient's anamnestic data, genetic testing.

Following the interim analysis, based on the results, another 800 people are planned to involve.

Study Overview

Status

Unknown

Conditions

Study Type

Observational

Enrollment (Anticipated)

1000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Hungary
      • Pécs, Hungary
        • University of Pécs 1st Department of Internal Medicine Intensive Care Unit
      • Pécs, Hungary
        • University of Pécs First Department of Internal Medicine
      • Pécs, Hungary
        • University of Pécs Infection Department of the Coronavirus Center
      • Pécs, Hungary
        • University of Pécs Institute of Laboratory Medicine
      • Pécs, Hungary
        • University of Pécs Szentágotahi Research Centre
      • Pécs, Hungary
        • University of Pécs Szentágothai Research Centre Genomics and Bioinformatics Core Facility
      • Pécs, Hungary
        • University of Szeged Szentágothai Research Centre Virology Research Group
      • Szeged, Hungary, 6720
        • University of Szeged Department of Anaesthesiology And Inthensive Therapy
      • Szeged, Hungary, 6720
        • University of Szeged Department of Dermatology and Allergology
      • Szeged, Hungary, 6720
        • University of Szeged Department of Medical Biology
      • Szeged, Hungary, 6720
        • University of Szeged Department of Paediatrics
      • Szeged, Hungary, 6720
        • University of Szeged First Department of Medicine
      • Szeged, Hungary, 6720
        • University of Szeged Institute of Clinical Microbiology
      • Szeged, Hungary, 6720
        • University of Szeged Institute of Medical Microbiology and Immunobiology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Adults

Description

Inclusion Criteria:

  • confirmed covid 19 infection

Exclusion Criteria:

  • informed refusal

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Identification of genetic factors determining the course of the disease in case of COVID-19
Time Frame: 2020. December
Exploring genotype-phenotype connections based on anamnestic data of patients and joint bioinformatics analysis of its genetic variants
2020. December

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Szeged University

Investigators

  • Principal Investigator: Márta Széll, MD, Ph.D., University of Szeged, Department of Medical Genetics

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

June 5, 2020

Primary Completion (ANTICIPATED)

December 31, 2020

Study Completion (ANTICIPATED)

July 31, 2021

Study Registration Dates

First Submitted

June 9, 2020

First Submitted That Met QC Criteria

June 9, 2020

First Posted (ACTUAL)

June 11, 2020

Study Record Updates

Last Update Posted (ACTUAL)

June 11, 2020

Last Update Submitted That Met QC Criteria

June 9, 2020

Last Verified

June 1, 2020

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • COVID19_HUNGEN_001

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on COVID-19

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kosovo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe