Clinical Trials on Progressive Massive Fibrosis in Japan

Total 123 results

Fresenius Kabi Japan

Completed

Study to Obtain Volume Effect and Safety Data on 6 % Hydroxyethyl Starch 130/0.4 in Pediatric and Adult Patients Undergoing Major Elective Surgery

Plasma Volume Substitution (Hypovolemia) Including Massive Hemorrhage

Japan
Toujinkai Hospital

Completed

Circulating P3NP and Cardiovascular Events in Hemodialysis Patients

Cardiac Fibrosis | Cardiovascular Events

Japan
National Center of Neurology and Psychiatry, Japan

Completed

Phase II Clinical Trial of OCH-NCNP1

Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive

Japan
Daiichi Sankyo Co., Ltd.

Completed

Study of Single-Ascending Doses of DS-6016a in Healthy Japanese Subjects

Fibrodysplasia Ossificans Progressiva

Japan
Boehringer Ingelheim

Completed

All-Case Surveillance of Ofev in Patients With IPF in Japan

Idiopathic Pulmonary Fibrosis

Japan
Takeda

Active, not recruiting

A Study of TAK-625 for the Treatment of Progressive Familial Intrahepatic Cholestasis (PFIC)

Progressive Familial Intrahepatic Cholestasis (PFIC)

Japan
Kobe University

Recruiting

To Evaluate the Efficacy of Alirocumab for Neoatherosclerosis by Using OCT, in Comparison With Standard Statin Therapy (POLARIS)

Coronary Artery Disease Progression

Japan
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary Fibrosis

China, United States, Japan, Korea, Republic of, Taiwan, Hungary, Canada, Argentina, Australia, Austria, Belgium, Brazil, Chile, Colombia, Czechia, Denmark, Finland, France, Germany, Greece, India, Ireland, Italy, Mexico, Netherlands, Peru, Polan... and more
ALDUS Study Group

Enrolling by invitation

Surveillance Study for HCC by Combining Biomarkers With Imaging (ALDUS) (ALDUS)

Liver Cirrhosis

Japan
AstraZeneca
MedImmune LLC

Completed

D2212C00002 J-Phase II Study

Idiopathic Pulmonary Fibrosis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study to Investigate Pharmacodynamics and Pharmacokinetics of OPC-41061 in Patients With Hepatic Edema

Cirrhosis

Japan
Biogen

Completed

A Safety and Efficacy Study of Oral Prolonged-Release Fampridine (BIIB041) in Japanese Participants With Multiple Sclerosis (MOTION - JAPAN)

Multiple Sclerosis | Relapsing-Remitting Multiple Sclerosis | Secondary Progressive Multiple Sclerosis | Multiple Sclerosis, Primary Progressive | Multiple Sclerosis, Remittent Progressive

Japan
Kobe University

Completed

Relation Among HDL Functionality, Neoatherosclerosis and Target Lesion Revascularization

Coronary Artery Disease Progression

Japan
Kanazawa University

Completed

Liver Regeneration Therapy by Intrahepatic Arterial Administration of Autologous Adipose Tissue Derived Stromal Cells

Liver Cirrhosis

Japan
Kanazawa University

Terminated

Liver Regeneration Therapy Using Autologous Adipose Tissue Derived Stromal Cells

Liver Cirrhosis

Japan
Rohto Pharmaceutical Co., Ltd.

Completed

An Follow-Up Study of Liver Cirrhosis

Decompensated Liver Cirrhosis

Japan
Boehringer Ingelheim

Completed

Safety and PK Study of BIBF 1120 in Japanese Patients With IPF: Follow up Study From 1199.31(NCT01136174)

Pulmonary Fibrosis

Japan
Rohto Pharmaceutical Co., Ltd.

Completed

A Study of ADR-001 in Patients With Liver Cirrhosis

Decompensated Liver Cirrhosis

Japan
Alcon Research

Completed

A Phase III Study of A01016 in Subjects With Symptomatic Vitreomacular Adhesion

Symptomatic Vitreomacular Adhesion

Japan
Boehringer Ingelheim

Completed

Safety and PK Study of BIBF 1120 in Japanese Patients With IPF

Idiopathic Pulmonary Fibrosis

Japan
National Center for Global Health and Medicine,...
Ministry of Health, Labour and Welfare, Japan

Unknown

HIV Liver Regeneration Project for HIV Patients With Cirrhosis by Autologous Bone Marrow Transplantation (HIV-ABMi)

HIV Infection | Cirrhosis | AIDS

Japan
Tokyo University
Japan Agency for Medical Research and Development; Zenyaku Kogyo Co., Ltd.

Completed

A Study of the Efficacy and Safety of Rituximab in Participants With Systemic Sclerosis (DesiReS)

Autoimmune Diseases | Collagen Diseases | Scleroderma, Systemic | Lung Fibrosis | Skin Sclerosis

Japan
Kyorin University

Completed

Efficacy Study of Water Drinking on PKD Progression. (ESWP)

Disease Progression | Autosomal Dominant Polycystic Kidney Disease

Japan
Shinshu University

Recruiting

To Examine Whether or Not the Primary Causes of OA or RA Might be Bone Alterations

Osteoarthritis of Multiple Joints | Progression of Rheumatoid Arthritis

Japan
Japan Liver Oncology Group

Unknown

Assessment of Liver FIBROsis by Real-time Tissue ELASTography in Chronic Liver Disease (FIBROELAST)

Chronic Hepatitis B | Chronic Hepatitis C

Japan
Komagome Hospital
Japan Agency for Medical Research and Development; Prism Pharma Co., Ltd.

Completed

A Follow-up Evaluation Study of PRI-724-1101

Hepatitis C Virus-infected Cirrhosis

Japan
Bayer

Completed

Special Drug Use Investigation of Ciproxan Injection in Pediatrics

Cystitis / Pyelonephritis / Cystic Fibrosis / Anthrax

Japan
Translational Research Center for Medical Innovation...
Kyoto University

Completed

Effects of Immunosuppression on HCV Recurrence After Living Donor Liver Transplantation - Comparative Study Between Tacrolimus + MMF and Tacrolimus + Steroid

Liver Cirrhosis | Hepatitis C

Japan
Komagome Hospital
Japan Agency for Medical Research and Development; Prism Pharma Co., Ltd.

Completed

An Open Label, Single Arm, Dose Escalation Phase 1 Trial of PRI-724 in Patients With HCV-induced Cirrhosis

Hepatitis C Virus-infected Cirrhosis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Trial of OPC-41061 in Patients With Hepatic Edema - Investigation of the Safety of Treatment at 7.5 mg Beyond 7 Days and of the Effect of Dose Escalation to 15 mg

Cirrhosis

Japan
AbbVie

Terminated

An Extension Study of ABBV-8E12 in Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy (PSP)

United States, Australia, Canada, Italy, Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Dose-defining Study of OPC-41061 in Treatment of Hepatic Edema

Cirrhosis

Japan
Asahi Kasei Pharma Corporation

Completed

Clinical Study of ART-123 for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Trial to Investigate the Efficacy of OPC-41061 Administered at a Dose of 7.5 mg in Patients With Hepatic Edema

Cirrhosis

Japan
Teikyo University

Completed

Nalfurafine Hydrochloride for Pruritus in Patients With Primary Biliary Cholangitis

Primary Biliary Cirrhosis

Japan
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Primary Biliary Cholangitis

United States, Japan
Kiminori Kimura, MD
Japan Agency for Medical Research and Development; Ohara Pharmaceutical Co....

Completed

Safety, Tolerability of OP-724 in Patients With Primary Biliary Cholangitis (Phase I)

Liver Cirrhosis, Biliary | Primary Biliary Cholangitis (PBC)

Japan
Mylan Inc.

Completed

Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Digestive System Diseases | Pancreatic Diseases | Cystic Fibrosis | Exocrine Pancreatic Insufficiency

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRA-027 in Japanese Postmenopausal Women

Uterine Leiomyomata (Fibroids)

Japan
Kissei Pharmaceutical Co., Ltd.

Active, not recruiting

A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia

Uterine Fibroids (MeSH Heading: Leiomyoma)

Japan
Kissei Pharmaceutical Co., Ltd.

Active, not recruiting

A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia and Pain

Uterine Fibroids (MeSH Heading: Leiomyoma)

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRA-027 Administered to Healthy Japanese Females

Uterine Leiomyomata (Fibroids)

Japan
Novartis Pharmaceuticals

Completed

Long Term Special Drug Use-results Surveillance for Mayzent in SPMS Patients

Secondary Progressive Multiple Sclerosis (SPMS)

Japan
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) With Lenvatinib (E7080/MK-7902) vs. Docetaxel in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) and Progressive Disease (PD) After Platinum Doublet Chemotherapy and Immunotherapy (MK-7902-008/E7080-G000-316/LEAP-008)

Metastatic Non-Small Cell Lung Cancer

Russian Federation, Australia, United States, Argentina, Canada, Colombia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Portugal, Puerto Rico, Spain, United Kingdom
Kiminori Kimura, MD
Japan Agency for Medical Research and Development; Ohara Pharmaceutical Co....

Completed

Safety and Tolerability Study of OP-724 in Liver Cirrhosis Patients by HIV/HCV With Hemophilia.

Liver Cirrhosis

Japan
Clementia Pharmaceuticals Inc.
Ipsen

Recruiting

A Study to Assess the Effectiveness and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP). (FALKON)

Fibrodysplasia Ossificans Progressiva

United States, Korea, Republic of, Belgium, China, Sweden, France, Japan, Argentina, Australia, Brazil, Canada, Italy, Spain, United Kingdom, Mexico, Colombia, Netherlands, Germany, Portugal
Novartis Pharmaceuticals

Active, not recruiting

Special Drug-use Surveillance for Kesimpta for s.c. Injection 20 mg Pen

Relapsing-remitting Multiple Sclerosis | Active Secondary Progressive Multiple Sclerosis

Japan
Nitto Denko Corporation

Completed

JUNIPER: A Phase 2 Study to Evaluate the Safety, Biological Activity, and PK of ND-L02-s0201 in Subjects With IPF

Idiopathic Pulmonary Fibrosis

United States, Germany, Japan, United Kingdom
University of Jazan

Completed

Comparison of Active Cycle of Breathing Technique and Pursed Lip Breathing With TheraPep

Chronic Obstructive Pulmonary Disease Exacerbation

Saudi Arabia
Actelion

Completed

Open Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443 (BUILD OL)

Idiopathic Pulmonary Fibrosis

United States, France, Spain, Korea, Republic of, United Kingdom, Belgium, Japan, Australia, Canada, Czech Republic, Germany, Ireland, Israel, Italy, Switzerland

Clinical Trials on Progressive Massive Fibrosis in Japan

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