Clinical Trials on Progressive Malignant Brain Tumor

Total 3996 results

Xinqiao Hospital of Chongqing

Recruiting

A Real-world Study of the Efficacy and Safety of ICIs as First-line Therapy for Advanced Malignancies

Artificial Intelligence | Malignant Tumor | Immunotherapy

China
Beijing Tiantan Hospital

Not yet recruiting

Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma (CSAγδTBMG)

Medulloblastoma | GBM | DIPG Brain Tumor

China
St. Jude Children's Research Hospital
National Cancer Institute (NCI)

Completed

Working Memory Performance Among Childhood Brain Tumor Survivors

Brain Tumors

United States
Children's Hospital of Philadelphia
Thrasher Research Fund

Completed

Arterial Spin Labeling Perfusion Magnetic Resonance (MR) Imaging in Pediatric Brain Tumors

Brain Tumors

United States
Assistance Publique - Hôpitaux de Paris
Institut National de Recherche en Informatique et en Automatique

Unknown

Liver Resection Modeling (LRM)

Cirrhosis | Benign Liver Tumor | Malignant Tumor Liver
Leap Therapeutics, Inc.
Cancer Research Institute, New York City

Completed

Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors (TRX518-001)

Unresectable Stage III or Stage IV Malignant Melanoma or Other Solid Tumor Malignancies

United States
Akeso

Not yet recruiting

A Study to Evaluate the Safety, Tolerance, Pharmacokinetics, and Preliminary Antineoplastic Activity of AK132 in Advanced Malignant Solid Tumor

Advanced Malignant Solid Tumor

China
GE Healthcare

Recruiting

A Study to Evaluate GEH200520/GEH200521 (18F) Safety and Tolerability When Used for PET Scans in Patients With Solid Tumour Malignancies

Oncology | Malignant Solid Tumor

Netherlands
SUNHO（China）BioPharmaceutical CO., Ltd.

Recruiting

A Clinical Trial to Evaluate the Effect of IAE0972 in Patients With Advanced Malignant Solid Tumors.

Advanced Malignant Solid Tumor

China
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors

Advanced Malignant Solid Tumor

China
CNBG-Virogin Biotech (Shanghai) Ltd.

Recruiting

Clinical Study of VG161 in Subjects With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumor

China
Molecular Partners AG

Terminated

First-in-human Safety and Tolerability of MP0317 in Patients With Relapsed/Refractory Advanced Solid Tumors

Advanced Malignant Solid Tumor

Netherlands, France
Masonic Cancer Center, University of Minnesota

Completed

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Soft Tissue Sarcoma | Medulloblastoma | Retinoblastoma | Rhabdomyosarcoma | Hepatoblastoma | Primary Malignant Brain Neoplasms | CNS Tumors | Germ Cell Tumors | Ewing's Family Tumors | Renal Tumors | Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET) | Atypical Teratoid/Rhabdoid Tumor (AT/RT)

United States
Masaryk Memorial Cancer Institute

Unknown

Acupuncture as the Therapeutic Modalities of Acute Toxicity in the Radiotherapy of Head and Neck Tumors

Malignant Tumor of Soft Tissue of Head, Face and Neck

Czechia
DNAtrix, Inc.
Merck Sharp & Dohme LLC

Completed

Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects (CAPTIVE)

Nervous System Diseases | Glioma | Glioblastoma | Neuroectodermal Tumors | Brain Cancer | Gliosarcoma | Brain Neoplasm | Malignant Brain Tumor | Neoplasm, Neuroepithelial | Neoplasm by Histologic Type | Neoplasm, Nerve Tissue

United States, Canada
City of Hope Medical Center

Active, not recruiting

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

Unspecified Childhood Solid Tumor, Protocol Specific | Solid Tumor | Ewing Sarcoma | Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Adult Brain Tumor | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Completed

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Ovarian Carcinoma | Pancreatic Neuroendocrine Tumor | Unresectable Solid Neoplasm | Fibrolamellar Carcinoma

United States
Henry Ford Health System

Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Malignant Astrocytoma

United States
Children's National Research Institute

Recruiting

International Rare Brain Tumor Registry (IRBTR)

Astroblastoma | BCOR ITD Sarcoma | CNS Sarcoma | Unclassified Tumor, Malignant

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Temozolomide in Association With Topotecan in Refractory or Relapsed Malignant Tumors in Children and Adolescents

Malignant Tumors | Refractory Tumors

France
Novelwise Pharmaceutical Corporation

Recruiting

NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma

Malignant Neoplasm | Malignant Neoplasm of Brain

Taiwan
Katy Peters
Merck Sharp & Dohme LLC; Genentech, Inc.

Completed

Suberoylanilide Hydroxamic Acid (SAHA), Bevacizumab, Daily Temozolomide for Recurrent Malignant Gliomas

Glioblastoma | Brain Tumor

United States
Bambino Gesù Hospital and Research Institute

Recruiting

GD2-CAR T Cells for Pediatric Brain Tumours

High Grade Glioma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Embryonal Tumor | Brain Tumor Adult | Brain Tumor, Pediatric

Italy
Medical University of Vienna

Unknown

Disease Progression and Treatment-induced Alterations in Glioblastoma

Brain Tumor

Austria
Henan Cancer Hospital

Not yet recruiting

Application of LARS Ligament in Bone Prosthesis Replacement

Malignant Tumor

China
Ludwig Institute for Cancer Research
Daiichi Sankyo Co., Ltd.; Austin Health

Completed

Safety and Bioimaging Trial of DS-8895a in Patients With Advanced EphA2 Positive Cancers (LUD2014-002)

Malignant Solid Tumor | Metastatic EphA2 Positive Cancer

Australia
The Sixth Affiliated Hospital of Wenzhou Medical...
Zhejiang Qixin Biotech

Unknown

Interventional Therapy Sequential With the Fourth-generation CAR-T Targeting Nectin4/FAP for Malignant Solid Tumors

Nectin4-positive Advanced Malignant Solid Tumor

China
University Hospital, Montpellier

Completed

Deportalization, Venous Deprivation, Venous Congestion

Malignant Liver Tumor

France
Oslo University Hospital
Merck Sharp & Dohme LLC

Terminated

A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery

Malignant Peripheral Nerve Sheath Tumour (MPNST)

Norway
Ivy Brain Tumor Center
GlaxoSmithKline

Recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Glioblastoma | Brain Tumor | GBM | Brain Neoplasms, Adult, Malignant

United States
University of Alabama at Birmingham

Terminated

FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors

Pediatric Brain Tumors

United States
University of California, San Francisco

Completed

Pilot Study of Safety and Toxicity of Acquiring Hyperpolarized Carbon-13 Imaging in Children With Brain Tumors

Pediatric Brain Tumors

United States
SynCore Biotechnology Co., Ltd.

No longer available

Long-Term Compassionate Use Study for Continued Administration of SCB01A-01

Malignant Solid Tumour
Candel Therapeutics, Inc.
Boston Children's Hospital

Completed

A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors

Malignant Glioma | Recurrent Ependymoma

United States
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Children With Brain Tumors

Childhood Brain Tumors

United States
St. Jude Children's Research Hospital
Pfizer; Ipsen

Active, not recruiting

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Refractory Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Peripheral Primitive Neuroectodermal Tumor | Recurrent Rhabdoid Tumor | Recurrent... and other conditions

United States, Canada
Northwell Health

Recruiting

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Glioblastoma | Brain Cancer | Brain Tumor | GBM | Brain Neoplasm | Brain Neoplasm, Malignant | EGFR Gene Overexpression

United States
St. Jude Children's Research Hospital

Completed

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects

Brain Tumors | Central Nervous System Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain Tumors

Brain Tumors | Central Nervous System Tumors

United States, Australia, Canada
Children's Hospital Medical Center, Cincinnati

Terminated

High Dose Chemotherapy With Amifostine and Autologous Stem Cell Transplantation for High Risk Relapsed Pediatric Solid Tumors and Brain Tumors

Solid Tumors | Brain Tumors

United States
Ontario Clinical Oncology Group (OCOG)
Ontario Cancer Research Network

Completed

The Roles of Tissue Factor in Malignant Gliomas

Venous Thromboembolism | Brain Tumors

United States, Canada
PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Recruiting

CAR-T for r/r Malignant Tumors in Children

Child, Only | Malignant Tumor | CAR-T

China
Eye & ENT Hospital of Fudan University
Peking University Third Hospital; Zhongshan Ophthalmic Center, Sun Yat-sen... and other collaborators

Recruiting

Neoadjuvant Radiotherapy for Malignant Lacrimal Sac Tumors

Malignant Tumor of Lacrimal Drainage Structure

China
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Phase I Study of SHR9146 + SHR-1210 +/- Apatinib in Patients With Advanced Solid Tumors

Neoplasm Malignant | Tumor, Solid | Cancer, Metastatic

China
AIO-Studien-gGmbH
Novartis Pharmaceuticals; Assign Data Management and Biostatistics GmbH

Completed

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study (EVINEC)

Neuroendocrine Carcinoma, Grade 3 | Poorly Differentiated Malignant Neuroendocrine Carcinoma | Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3 | Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma]... and other conditions

Germany
University of Pittsburgh
National Institute of Nursing Research (NINR)

Completed

SmartCare: Innovations in Caregiving Interventions (SmartCare)

Primary Malignant Brain Tumors

United States
University of Texas at Austin
University of California, San Francisco; National Institute on Deafness and...

Active, not recruiting

Treatment for Speech and Language in Primary Progressive Aphasia

Primary Progressive Aphasia | Aphasia | Semantic Dementia | Logopenic Progressive Aphasia | Semantic Memory Disorder | Nonfluent Aphasia, Progressive | Aphasia, Progressive

United States
Erasmus Medical Center
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma (RECMAP)

Glioblastoma | Brain Neoplasms | Recurrent Glioblastoma | Recurrent Adult Brain Tumor | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme of Brain | Brain Neoplasms, Adult, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Switzerland, Belgium, Netherlands
Peking Union Medical College Hospital
Peking University; Peking University Cancer Hospital & Institute

Recruiting

BBPA PET/CT in Patients With Malignant Tumors

Malignant Tumors

China
Durham University
County Durham and Darlington NHS Foundation Trust

Suspended

Terahertz Metamaterials for Tumour Marker Concentration Identification

Malignant Tumour

United Kingdom

Clinical Trials on Progressive Malignant Brain Tumor

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