Clinical Trials on Proven or Suspected Gram-negative Bacterial Infection in Germany

Total 186 results

Novartis Vaccines

Completed

Efficacy and Safety of an H.Pylori Vaccine in H.Pylori-Negative Adults

Helicobacter Pylori Infection

Germany
Hospital Clinic of Barcelona

Recruiting

Arrangement of Collecting Venules for the Endoscopic Diagnosis of Helicobacter Pylori (MOTIVATION)

Helicobacter Pylori Infection

Spain, Belgium, Germany
Novartis
Novartis Vaccines

Completed

Safety, Tolerability and Immunogenicity of Meningococcal C Conjugate Vaccine to Children 32 to 40 Months of Age

Meningococcal Infection

Germany
University of Erlangen-Nürnberg Medical School

Completed

Immediate Detection of Helicobacter Infection With a New Electrochemical System.

H. Pylori Infection

Germany
University Hospital Freiburg

Recruiting

Pathogen-microbiome Interaction During Helicobacter Pylori Infection (PREDICTHP)

Helicobacter Pylori Infection

Germany
University Medical Centre Ljubljana

Withdrawn

The Effect of Probiotic Combination on Helicobacter Pylori Infection in Children (Gastrus)

Helicobacter Infections

Israel, Belgium, Croatia, Germany, Slovenia
MerLion Pharmaceuticals GmbH

Completed

Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected Patients (FLASH)

Dyspepsia | Gram-Negative Bacterial Infections | Helicobacter Infections

Germany
Valneva Austria GmbH

Completed

Study Assessing Safety and Immunogenicity of IC43 Vaccination Against Pseudomonas Aeruginosa in Healthy Volunteers

Healthy

Austria, Germany
GlaxoSmithKline

Completed

Safety and Immunogenicity of an Aluminium Hydroxide/LHD153R Adjuvanted Meningococcal C-CRM197 Conjugate Vaccine

Infections, Meningococcal

Germany
Valneva Austria GmbH

Completed

Confirmatory Phase II/III Study Assessing Efficacy, Immunogenicity and Safety of IC43

Pseudomonas Aeruginosa Infection

Spain, Germany, Belgium, Austria, Czech Republic, Hungary
Novartis Vaccines

Completed

Immunogenicity, Safety, Tolerability and Ability to Prime for Memory of Meningococcal C Conjugate Vaccine in Healthy Children

Prevention of Meningococcal Infection

Germany, Poland
UMC Utrecht
Janssen Research & Development, LLC; Innovative Medicines Initiative

Completed

Study to Collect Information About Invasive Disease Caused by Extraintestinal Pathogenic Escherichia Coli-2 (EXPECT-2) (EXPECT-2)

E. Coli Infection

United States, Italy, United Kingdom, Canada, France, Germany, Japan, Spain
University of Cologne

Recruiting

Leptospirosis Registry - LeptoScope (Leptoscope)

Leptospirosis

Germany
University Hospital of Cologne
Charite University, Berlin, Germany; University Hospital Tuebingen; University... and other collaborators

Completed

Antibiotic Stewardship and Infection Control in Patients at High Risk of Developing Infection by Clostridium Difficile, Vancomycin-Resistant Enterococci or Multi-Resistant Gram-Negatives (ABSOLUTE)

Clostridium Difficile Infection | Nosocomial Infection | VRE Infection | MRGN Bacteria

Germany
Poitiers University Hospital

Recruiting

New Strategy for the Detection and Treatment of Helicobacter Pylori Infections in Primary Care Guided by a Non-invasive PCR in Stool

Helicobacter Pylori Infection

France
Novartis Vaccines
GlaxoSmithKline

Completed

A Phase 3b, Single-Center, Open-label Study to Assess the Immunogenicity and Safety of Novartis Meningococcal B Recombinant Vaccine When Administered at a 0, 2-Month Schedule in Healthy At-Risk Adults Aged 18 to 65 Years Inclusive.

Prevention of the Meningococcal Disease

Germany
Novartis

Completed

Pharmacokinetic Evaluation of an 8 -Week Treatment With Inhaled Tobramycin

Pseudomonas Infections

Germany
Pfizer

Completed

Duration of hSBA Response After a Primary Series of Bivalent rLP2086 Followed by a Booster Dose

Meningococcal Infection

United States, Finland, Czechia, Sweden, Denmark, Germany
AlgiPharma AS

Completed

A Study of OligoG in Cystic Fibrosis Subjects With Burkholderia Spp. Infection (SMR-2591)

Cystic Fibrosis | Burkholderia Infection

Germany
LimmaTech Biologics AG
GlaxoSmithKline

Completed

Safety and Immunogenicity of a Klebsiella Pneumoniae Tetravalent Bioconjugate Vaccine (Kleb4V)

Klebsiella Pneumoniae Infection

Germany
Technische Universität Dresden

Unknown

Esomeprazole, Moxifloxacin and Amoxicilin for Rescue Therapy of Helicobacter Pylori Infection (ESAMOX)

Helicobacter Pylori Infection | Chronic Gastritis

Germany
MJM Bonten
Janssen Research & Development, LLC; Innovative Medicines Initiative

Completed

Study to Collect Information About Invasive Disease Caused by Extraintestinal Pathogenic Escherichia Coli (EXPECT-1) (EXPECT-1)

E.Coli Infections

United States, United Kingdom, Canada, France, Germany, Italy, Japan, Spain
University Hospital Tuebingen

Completed

Anti-Inflammatory Pulmonal Therapy of CF-Patients With Amitriptyline and Placebo

Cystic Fibrosis | Infection | Pseudomonas Aeruginosa

Germany
GlaxoSmithKline

Completed

Comparison of GSK Biologicals' Meningococcal Vaccine (GSK134612) and Licensed MenC-CRM197 Vaccine in Healthy Children

Infections, Meningococcal

Germany, France
GlaxoSmithKline

Completed

Study in Children to Evaluate the Immunogenicity and Safety of 4 Formulations of GSK Bio MenACWY-TT Conjugate Vaccine

Infections, Meningococcal

Germany, Austria
GlaxoSmithKline

Completed

Persistence and Booster Study of GSK Biologicals' Meningococcal Vaccine (GSK134612) in Healthy Children

Infections, Meningococcal | Meningococcal Vaccines

Germany, France
Jena University Hospital
Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany

Unknown

NExt-Generation Sequencing and Cell Culture-based Characterization of S. Aureus in Infective Endocarditis (NESSIE)

Infective Endocarditis | Infection Staphylococcal

Germany
Sanofi Pasteur, a Sanofi Company

Completed

Study on a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Compared to Two Meningococcal Reference Vaccines in European Toddlers

Meningococcal Immunisation (Healthy Volunteers)

Denmark, Finland, Germany
Sanofi Pasteur, a Sanofi Company

Active, not recruiting

Study on an Investigational Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Administered as a 5- and/or 10-year Booster Doses in Children and Adolescents Vaccinated 5 or 10 Years Earlier as Toddlers

Healthy Volunteers | Meningococcal Immunisation

Spain, Finland, Germany, Hungary
BG Unfallklinik

Completed

Biofilm Formation in Staphylococcus Epidermidis Associated Implant Infections

Staphylococcal Infections

Germany
Lyme Diagnostics Ltd.
Pharmahungary Group

Completed

Performance Evaluation of the DualDur In Vitro Diagnostic System in the Diagnosis of Lyme Borreliosis

Lyme Borreliosis

Austria, Czechia, Germany, Hungary, Poland, Slovakia
GlaxoSmithKline

Active, not recruiting

A Study on the Safety, Tolerability and Immune Response of Meningococcal Combined ABCWY Vaccine in Healthy Infants

Infections, Meningococcal

Finland, Poland, Spain, United Kingdom, Germany, South Africa, Dominican Republic, Israel, Honduras
Novartis Vaccines

Completed

Safety, Tolerability and Immunogenicity of Meningococcal B Recombinant Vaccine Administered With or Without Routine Infant Vaccinations to Healthy Infants According to Different Immunization Schedules

Meningococcal Infections

Belgium, Czech Republic, Germany, Italy, Spain, United Kingdom
Baxalta now part of Shire
Baxter Innovations GmbH

Completed

Phase 1/2 Lyme Vaccine Study

Prophylaxis of Lyme Borreliosis

Germany, Austria
Pfizer

Completed

Immunogenicity and Safety Study of a Vaccine Against Lyme Borreliosis, in Healthy Adults Aged 18 to 65 Years. Randomized, Controlled, Observer-blind Phase 2 Study.

Lyme Borreliosis

United States, Germany, Belgium
Novartis Vaccines

Completed

Extension Study of V72P13 to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered as a Booster or as a Two-dose Catch-up to Healthy Toddlers

Meningococcal Disease

Austria, Finland, Germany, Italy, Czech Republic
University Hospital Muenster
GlaxoSmithKline

Completed

Prophylaxis With Intranasal Mupirocin for Prevention of S. Aureus Infections

Cross Infection | Staphylococcal Infections

Germany
University Hospital Tuebingen

Unknown

Fecal Microbiota Transplantation in Recurrent or Refractory Clostridium Difficile Colitis (TOCSIN)

Clostridium Difficile Infection | Clostridium Difficile

Germany
Novartis Pharmaceuticals

Terminated

Evaluation of Lung Clearance Index in Cystic Fibrosis (CF) Patients, Infected With P.Aeruginosa (ELIXIR)

Chronic Lung Infection With Pseudomonas Aeruginosa in Cystic Fibrosis

Germany
University Hospital, Essen

Completed

PRetest prObability of Infectious ENDOCARDITIS for Appropriate Criteria Regarding Transesophageal ECHOcardiography in Tertiary Care Facilities (PRO ENDOCARDITIS ECHO-Study)

Infective Endocarditis

Germany
Novartis Vaccines

Completed

Persistence Of Antibody Responses Among Children Who Previously Received Novartis MenACWY Conjugate Vaccine or Meningococcal C Conjugate Vaccine

Meningococcal Disease

Germany
GlaxoSmithKline

Completed

Co-Administration of Meningococcal Vaccine GSK134612 With Infanrix Hexa™ Versus Individual Administration of Each Vaccine

Infections, Meningococcal

Germany, Austria, Greece
University Hospital Tuebingen

Completed

Tocilizumab for the Treatment of Familial Mediterranean Fever

Familial Mediterranean Fever

Germany
GlaxoSmithKline

Completed

Immunogenicity and Safety of Meningococcal Vaccine GSK 134612 Co-administered With Pneumococcal and DTPa-HBV-IPV/Hib Vaccines

Infections, Meningococcal | Meningococcal Vaccines

Estonia, Germany, Spain
GlaxoSmithKline

Completed

A Study to Investigate the Safety and Immunogenicity of Different Formulations of GSK Biologicals' Meningococcal ACWY Conjugate Vaccine (GSK3536820A and Menveo) Administered to Healthy Adults 18 to 40 Years of Age

Infections, Meningococcal

Germany, Canada, Australia, Belgium, Italy
University of Jena

Completed

Nasal Inhalation of Tobramycin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization

Cystic Fibrosis | Pseudomonas Aeruginosa

Germany
University of Jena

Completed

Sino-nasal Inhalation of Colistin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization

Cystic Fibrosis | Pseudomonas Aeruginosa

Germany
GlaxoSmithKline

Completed

Assessment of GSK Biologicals' Tdap Candidate Vaccine Administered as a Booster (6th Dose) in Terms of Immunogenicity and Safety to Children and Adolescents Previously Vaccinated With Five Doses of an Acellular Pertussis-containing Vaccine.

Tetanus | Diphtheria | Acellular Pertussis

Germany
Astellas Pharma Europe Ltd.
Cubist Pharmaceuticals LLC

Terminated

A Post-marketing, Blinded Study to Investigate How Effective Fidaxomicin is Compared to Vancomycin in the Sustained Cure of Clostridium Difficile Infection in Adults That Are Receiving Therapy to Suppress the Immune System (FREEDOM)

Clostridium Difficile

Spain, France, Germany, Greece, Denmark, Austria, Poland
GlaxoSmithKline

Completed

A Sourcing Study to Collect Human Blood Samples From Healthy Adults

Meningitis, Meningococcal

Australia, Germany

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