Clinical Trials on Pulmonary Emphysema in Czechia

Total 224 results

Carebot s.r.o.

Completed

Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical Practice

Pneumothorax | Subcutaneous Emphysema | Cardiomegaly | Pleural Effusion | Atelectasis | Pulmonary Nodule, Solitary | Consolidation

Czechia
Thomayer University Hospital
Masaryk University

Recruiting

Czech AATD Registry

Alpha-1-antitrypsin Deficiency

Czechia
St. Anne's University Hospital Brno, Czech Republic

Completed

Rest Ventilatory Parameters Predict Morbidity and Mortality in Thoracic Surgery

Pulmonary Complication | Cardiovascular Complication

Czechia
Hoffmann-La Roche

Completed

TESRA: (Treatment of Emphysema With a Gamma-Selective Retinoid Agonist)

Emphysema

United States, South Africa, Hungary, Poland, Bulgaria, Latvia, Israel, Italy, Czech Republic, United Kingdom, Ukraine, Iceland
CSL Behring

Completed

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Emphysema | Alpha1-proteinase Inhibitor Deficiency

Australia, Russian Federation, United States, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden, Canada, Czech Republic
CSL Behring

Completed

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Emphysema | Alpha 1-proteinase Inhibitor Deficiency

Australia, Canada, Czech Republic, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden
University Hospital Ostrava

Completed

Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients

Septic Shock | Respiratory Insufficiency | Hypoxemia | Chronic Obstructive Pulmonary Disease Exacerbation | Lung Ventilator | Hyperhydration | Respiratory Distress Syndrome, Acute

Czechia
Brno University Hospital

Active, not recruiting

Inspiratory Muscle Training and COPD

Chronic Obstructive Pulmonary Disease

Czechia
University Hospital Olomouc

Recruiting

HFpEF and 2-year Mortality of COPD Patients (THERESE)

Heart Failure | Chronic Obstructive Pulmonary Disease

Czechia
Institute for Clinical and Experimental Medicine

Not yet recruiting

Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure (LUNG-HF)

Heart Failure | Pulmonary Hypertension | Pulmonary Vascular Resistance Abnormality

Czechia
Emergency Medical Service of the Central Bohemian...
Masaryk Hospital Usti nad Labem; Institute of Experimental Physics, Slovak...

Completed

Cosmic Weather and Cardiogenic Pulmonary Edema

Pulmonary Edema Cardiac Cause

Czechia
General University Hospital, Prague

Completed

Catheter Ablation of Atrial Fibrillation in Patients With Pulmonary Hypertension Hypertension: a Randomised Study

Atrial Fibrillation | Pulmonary Hypertension

Czechia
SciPharm SàRL

Completed

Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH) (CTREPH)

Non-operable Chronic Thromboembolic Pulmonary Hypertension

Austria, Poland, Czechia, Germany
Carebot s.r.o.

Completed

Retrospective Study of Carebot AI CXR Performance in Preclinical Practice

Pneumonia | Lung Diseases | Pneumothorax | Lung Cancer | Cardiomegaly | Artificial Intelligence | Pulmonary Edema | Pleural Effusion | Atelectasis | Consolidation | Hilar Calcification | Fracture Rib

Czechia
Faculty Hospital Kralovske Vinohrady
University Hospital Ostrava; University Hospital Olomouc; University Hospital... and other collaborators

Recruiting

Catheter-directed Thrombolysis in Intermediate-high Risk Acute Pulmonary Embolism (PRAGUE-26)

Pulmonary Embolism

Czechia
Regional Hospital Liberec
Charles University, Czech Republic; University of Sao Paulo; Technology Agency...

Recruiting

The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance Tomography (N-LAT-EIT)

Lung Collapse

Czechia
Boehringer Ingelheim

Completed

OTIVACTO Regional Center Vienna (RCV) Non-Interventional Study (NIS)

Pulmonary Disease, Chronic Obstructive

Austria, Czechia, Hungary, Israel, Romania, Russian Federation, Slovakia, Slovenia, Switzerland
GlaxoSmithKline

Completed

A Study to Assess the Effects of Repeat Doses of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Severe Impairment.

Pulmonary Disease, Chronic Obstructive

Czechia
Zuzana Zbožínková, M.Sc.

Unknown

Czech Multicentre Research Database of Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Airway Disease

Czechia
University Hospital Ostrava
Municipal Hospital Ostrava Fifejdy; Silesian Hospital Opava

Completed

Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism (CONTACT-SPE)

Pulmonary Embolism

Czechia
Bayer

Completed

This Study Tests the Safety of Inhaled BAY1237592, How the Drug is Tolerated and How it Effects Patients With High Blood Pressure in the Arteries of the Lungs in the Two Different Disease Groups Pulmonary Arterial Hypertension (PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH) (ATMOS)

Hypertension, Pulmonary

Germany, Czechia, Austria, Poland
University Hospital Ostrava
Municipal Hospital Ostrava; University Hospital Olomouc; University of Ostrava; Public Health Institute Ostrava and other collaborators

Recruiting

Early Diagnosis of Invasive Lung Aspergillosis

Invasive Pulmonary Aspergillosis | Respiratory Infection

Czechia
Novartis Pharmaceuticals

Completed

Study of Effect of CSJ117 on Symptoms, Pharmacodynamics and Safety in Patients With COPD

Pulmonary Disease, Chronic Obstructive

United States, Australia, Canada, Hungary, Japan, Czechia
The Institute of Molecular and Translational Medicine...
University Hospital Olomouc

Recruiting

Pulmonary Condensate: Non-invasive Evaluation of Pulmonary Involvement in Asthma and Cystic Fibrosis.

Bronchial Asthma | Pulmonary Cystic Fibrosis

Czechia
GlaxoSmithKline

Completed

Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment

Pulmonary Disease, Chronic Obstructive

Czechia, Hungary
Ionis Pharmaceuticals, Inc.

Terminated

A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

Germany, Czechia, Hungary, United Kingdom
AstraZeneca

Completed

Efficacy and Safety of Two Fixed Dose Combinations of Aclidinium Bromide With Formoterol Fumarate (ALIGHT-COPD)

Chronic Obstructive Pulmonary Disease

Romania, Czech Republic
Lung Biotechnology PBC

Completed

Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) Patients

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
AOP Orphan Pharmaceuticals AG

Enrolling by invitation

A Prospective Non-interventional Observational Study to Observe Long-term Treatment and Outcomes in Pulmonary Arterial Hypertension (PAH) Patients (TripleTRE-NIS)

Pulmonary Arterial Hypertension

France, Spain, Germany, Italy, Hungary, Austria, Czechia, Poland, Romania
Lung Biotechnology PBC

Completed

Dose-response Study of the Safety and Efficacy of Beraprost Sodium Modified Release (BPS-MR) in Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
AstraZeneca

Completed

Aclidinium/Formoterol Fixed Combination Dose Finding Study

Chronic Obstructive Pulmonary Disease (COPD)

Russian Federation, Australia, Czech Republic, Poland
AOP Orphan Pharmaceuticals AG
GCP-Service International Ltd. & Co. KG; ANOVA CRO s.r.o.; PharmaLex Belgium; Aixial...

Recruiting

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients (TripleTRE)

Pulmonary Arterial Hypertension

Austria, Spain, France, Germany, Italy, Czechia, Hungary, Poland, Portugal, Romania
Chiesi Farmaceutici S.p.A.

Completed

Study to Evaluate Efficacy/Safety of 4 Doses of CHF5259 Via Dry Powder Inhaler (DPI) in Patients With COPD (GlycoNEXT)

Chronic Obstructive Pulmonary Disease (COPD)

Czechia, Germany, Hungary, Romania
Value Outcomes Ltd.
AstraZeneca

Completed

Characteristics of Type 2- High Inflammatory Endotype of Asthma Using New Biomarkers From Peripheral Blood and Exhaled Air and Its Effect on the Outcome of Therapy

Asthma, Bronchial | Bronchial Asthma | Asthma Chronic | Asthma; Eosinophilic

Czechia
International CTEPH Association

Completed

International BPA Registry

Chronic Thromboembolic Pulmonary Hypertension | CTEPH

United States, Japan, Belgium, United Kingdom, Netherlands, Czechia, Germany, Austria, France, Poland
GlaxoSmithKline

Completed

A Study to Evaluate the Effect of Umeclidinium (UMEC) as Combination Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Netherlands, Greece, Czechia
United Therapeutics

Completed

Safety and Efficacy of APD811 in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, Australia, Hungary, Bulgaria, Czechia, Poland, Romania, Serbia, Spain
Mereo BioPharma

Completed

Efficacy and Safety of BCT197 in Subjects With Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United States, Bulgaria, Czechia, Germany, Hungary, Italy, Latvia, Poland, Romania, Russian Federation
AstraZeneca

Completed

Efficacy and Safety of Aclidinium Bromide 400 µg Compared to Placebo and to Tiotropium Bromide in Patients With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

Czech Republic, Germany, Hungary, Poland
Janssen Research & Development, LLC

Completed

An Effectiveness and Safety Study of Inhaled JNJ 49095397 (RV568) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom, United States, Belgium, Germany, Romania, Canada, Netherlands, Russian Federation, Poland, Hungary, Czechia
Actelion

Completed

Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (MERIT-2)

Chronic Thromboembolic Pulmonary Hypertension

Poland, Ukraine, United Kingdom, China, Russian Federation, Belgium, Germany, Thailand, Hungary, France, Lithuania, Czechia, Mexico, Switzerland, Turkey
GlaxoSmithKline

Completed

Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-centre, Dose Ranging Study to Evaluate the Efficacy and Safety of Losmapimod Tablets Administered Twice Daily Compared With Placebo for 24 Weeks in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD).

Pulmonary Disease, Chronic Obstructive

United States, Argentina, Germany, Estonia, Ukraine, Korea, Republic of, Norway, Czechia
Hoffmann-La Roche

Completed

A Trial to Evaluate the Efficacy of PRM-151 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States, Netherlands, Italy, Germany, Switzerland, Czechia, Spain
Pfizer

Completed

A Phase II, Study To Evaluate The Efficacy And Safety Of PH-797804 In Adults With Moderate To Severe Chronic Obstructive Pulmonary Disease (COPD).

Chronic Obstructive Pulmonary Disease

Australia, Netherlands, Canada, Korea, Republic of, Argentina, Hungary, South Africa, France, Russian Federation, Chile, Czechia, Greece, United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, Czechia, Germany, Israel, France, Australia, Taiwan, Greece, Italy, United Kingdom
Actelion

Completed

Clinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (MERIT-1)

Chronic Thromboembolic Pulmonary Hypertension

United Kingdom, Belgium, Ukraine, Germany, Switzerland, Hungary, China, Korea, Republic of, Mexico, Czechia, France, Lithuania, Poland, Russian Federation, Thailand, Turkey
GlaxoSmithKline

Completed

A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, United States, Netherlands, Czechia
Actelion

Completed

FUTURE 3 Study Extension (FUTURE 3 Ext)

Pulmonary Arterial Hypertension

United States, Australia, Belarus, China, Czechia, France, Germany, Hungary, India, Israel, Italy, Mexico, Poland, Russian Federation, Serbia, South Africa, Spain, Ukraine
GlaxoSmithKline

Completed

A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC /VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Germany, Czechia
GlaxoSmithKline

Completed

An Exercise Endurance Study to Evaluate the Effects of Treatment of Chronic Obstructive Pulmonary Disease (COPD) Patients With a Dual Bronchodilator: GSK573719/GW642444.Study B (COPD)

Pulmonary Disease, Chronic Obstructive

South Africa, United States, Canada, Ukraine, United Kingdom, Denmark, Czechia

Clinical Trials on Pulmonary Emphysema in Czechia

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