Clinical Trials on RAS and BRAF Wild-type

Total 58059 results

RECORDATI GROUP

Completed

Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies

Prostate Cancer | Neuroendocrine Tumors | Acromegaly | Cushing's Disease | Dumping Syndrome | Pituitary Tumors | Ectopic ACTH Secreting (EAS) Tumors | Melanoma Negative for bRAF | Melanoma Negative for nRAS

Belgium, Brazil, Bulgaria, Canada, France, Germany, Italy, Japan, Korea, Republic of, Thailand, Turkey, United States, Argentina, Greece, Hungary, India, Israel, Malaysia, Mexico, Netherlands, Peru, Poland, Portugal, Romania, Russian Federation and more
Cancer Research UK
Hummingbird Bioscience

Recruiting

HMBD-001 in Advanced HER3 Positive Solid Tumours

Melanoma | Cervical Cancer | Gastric Cancer | Pancreatic Cancer | Ovarian Cancer | Hepatocellular Carcinoma (HCC) | Bladder Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Castration-resistant Prostate Cancer | Non-small Cell Lung Cancer (NSCLC) | Oesophageal Cancer | RAS Wild Type Colorectal Cancer | Squamous Cell Cancer of the Head and Neck

United Kingdom
Douglas Mental Health University Institute
McGill University; Weston Brain Institute

Completed

Dosage and Efficacy of Probucol-induced apoE to Negate Cognitive Deterioration (DEPEND)

Mild Cognitive Impairment Due to Alzheimer Disease | Age-related Cognitive Decline | Dementia of the Alzheimer Type

Canada
Kura Oncology, Inc.

Completed

Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy (AIM-HN/SEQ-HN)

HNSCC | HRAS Gene Mutation

United States, Belgium, Spain, United Kingdom, Taiwan, Denmark, Korea, Republic of, Netherlands, Thailand, Germany, Malaysia, Austria, Italy, Greece, Australia, Norway
AIO-Studien-gGmbH

Completed

Comparison of Two Preemptive Treatment Strategies of Panitumumab Mediated Skin Toxicity and Assessment of QoL in Patient With Ras-wt Colorectal Cancer

Ras-wildtype Colorectal Cancer

Germany
Tripler Army Medical Center
U.S. Army Medical Research Acquisition Activity

Unknown

Asthma In-Home Monitoring (AIM) Trial

Mild, Moderate and Severe Persistent Asthma as Defined by NHLBI-2 Guidelines

United States
Cuneyt M. Alper
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Trans-Middle-Ear Mucosal Gas Exchange Project 1, Specific Aim 1

Middle Ear Gas Exchange

United States
West Virginia University

Terminated

1% Topical Pimecrolimus Cream for the Treatment of the Rash Associated With ERBITUX

Rash

United States
Renew Research, LLC
Navitas Clinical Research, Inc; ClinEdge, LLC

Completed

Renew NCP-5 for the Treatment of Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild Dementia of the Alzheimer's Type

Cognitive Dysfunction | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Dementia, Alzheimer Type | Mild Dementia

United States, Singapore, Ireland
Chen Xiaoping

Completed

Postoperative Adjuvant Therapy of HCC Based on PD-1

Hepatocellular Carcinoma | RFS

China
Pfizer

Completed

A Phase Ib/II Study of LEE011 in Combination With MEK162 in Patients With NRAS Mutant Melanoma

Locally Advanced or Metastatic NRAS Mutant Melanoma

United States, Australia, Germany, Italy, Netherlands
University of Michigan
National Institute on Aging (NIA)

Enrolling by invitation

STIM+: PET Biomarker Education & Disclosure (STIM+)

Mild Cognitive Impairment | Dementia; Alzheimer's Type (Etiology)

United States
Acıbadem Atunizade Hospital

Recruiting

Re-Adjustment of Sweep Gas Flow to the During the Rewarming Period of the Cardiopulmonary Bypass

Optimal Sweep Gas Flow | Determination of Optimal Sweep Gas Flow for Different Phases of Cardiopulmonary Bypass

Turkey
China Medical University, Taiwan
Changhua Christian Hospital

Completed

Heart Rate Variability Assessment in Dialysis Patients by Acupuncture

RLS

Taiwan
Intergroupe Francophone de Cancerologie Thoracique
Amgen

Active, not recruiting

RW Efficacy of Sotorasib in KRAS G12C-mutated Metastatic NSCLC (LungKG12Ci)

Nsclc | KRAS P.G12C

France
Istituto Ortopedico Galeazzi

Completed

Sleep Behavior and Rest-activity Circadian Rhythm (RAR) in Hip/Knee Prosthesis (Sleep&RAR)

Pain | Sleep | Arthroplasty Complications | Hospitalization | RAR

Italy
Northwestern University
GlaxoSmithKline

Completed

Histological Characterization and Differentiation of Rash From Other Epidermal Growth Factor Receptor (EGFR) Inhibitors

Skin Rash

United States
University of Pittsburgh
OSI Pharmaceuticals

Withdrawn

Study of Acitretin to Treat Skin Rash Caused by Erlotinib (a Chemotherapy Drug)

Skin Rash

United States
Northwestern University
Bayer

Terminated

Sorafenib-induced Hand- Foot Skin Reaction Treatment

Rash | Hand-foot Skin Reaction

United States
Saglik Bilimleri Universitesi
Ankara University

Recruiting

Modified Ketogenic Diet in Amnestic Mild Cognitive Impairments

Amnestic Mild Cognitive Impairment | Amnestic Mild Cognitive Disorder

Turkey
Ege University

Not yet recruiting

The Effects of Three Different Techniques During PIVC

Pain | Visual Aura | Arm | Infrared; Rays, Injury

Turkey
The Second Hospital of Shandong University

Recruiting

Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery

Lung Cancer | Surgery | ERAS

China
Daewoong Pharmaceutical Co. LTD.

Completed

DWP708 for Treating Epidermal Growth Factor Receptor Inhibitor Related Skin Toxicities

Rash Acneiform

Korea, Republic of
Seoul National University Bundang Hospital

Completed

ERAS After Bariatric Surgery in Morbidly Obese

Obesity | ERAS

Korea, Republic of
XtremeVRI AG
Aristotle University Of Thessaloniki; Klinik Hirslanden, Zurich; Greek Alzheimer...

Completed

Cognitive/Physical Computer-Game Blended Training With Personalized Brain Network Activation Technology for the Elderly (AlterniityAR)

Healthy | Mild Cognitive Impairment, So Stated | Mild Dementia
Aristotle University Of Thessaloniki
Greek Alzheimer's Association and Related Disorders

Completed

Cognitive/Physical Computer-Game Blended Training of Elderly: Neuroscientific LLM Studies (LLM-AUTH)

Healthy | Mild Cognitive Impairment, So Stated | Mild Dementia
Intergroupe Francophone de Cancerologie Thoracique

Recruiting

ENCOrafenib With Binimetinib in bRAF NSCLC (ENCO-BRAF)

Non Small Cell Lung Cancer | BRAF V600E

France
Affini-T Therapeutics, Inc.

Recruiting

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

Colorectal Cancer | Non-Small Cell Lung Cancer | Solid Tumor | Pancreatic Ductal Adenocarcinoma | KRAS G12V

United States
Innovent Biologics (Suzhou) Co. Ltd.

Terminated

The Study of IBI310 in Combination With IBI308 Compared to High-Dose Interferon In Patients With Acral Melanoma That Has Been Removed by Surgery

Acral Melanoma That Has Been Removed by Surgery

China
University Hospital, Rouen

Completed

A Randomized Controlled Trial on the Effect of Needle Gauge on the Pain and Anxiety Experienced During Arterial Puncture

Pain | Blood Gas Analysis

France
Cognito Therapeutics, Inc.

Enrolling by invitation

Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)

Cognitive Impairment | Alzheimer Disease | Mild Cognitive Impairment | Dementia Alzheimers | Dementia of Alzheimer Type | AD | Dementia, Mild | Dementia Moderate

United States
Elicio Therapeutics

Active, not recruiting

A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors (AMPLIFY-201)

Colorectal Cancer | Ovarian Cancer | Cholangiocarcinoma | Bile Duct Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Minimal Residual Disease | Gallbladder Carcinoma | KRAS G12D | KRAS G12R | NRAS G12D | NRAS G12R

United States
Beijing Jishuitan Hospital

Enrolling by invitation

Does Medial Raw Anchor Necessary During Tendon Repair Combined With Microfracture

Full Rotator Cuff Tear | Microfracture Procedure | Double Raw Repair | Lateral Raw Repair

China
University of California, San Francisco
National Institute on Aging (NIA)

Active, not recruiting

Brain Health Together: A Live-Streaming Group-Based Digital Program

Mild Cognitive Impairment | Cognitive Decline | Cognitive Deterioration | Cognitive Impairment, Mild | Cognitive Deficits, Mild

United States
Temple University

Recruiting

Improving Everyday Task Performance Through Repeated Practice in Virtual Reality. (VKI)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Dementia, Vascular | Dementia, Mixed | Dementia Alzheimers | Mild Dementia | Dementia of Alzheimer Type | Dementia, Mild

United States
UNICANCER
Merck Sharp & Dohme LLC; Pierre Fabre Medicament; European Association of Dermato...

Active, not recruiting

Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis (BEPCOME-MB)

Brain Metastases | Malignant Melanoma | BRAF V600 Mutation

France
Temple University

Recruiting

Feasibility of the SmartPrompt for Improving Everyday Function in Dementia (SmartPrompt)

Dementia | Mild Cognitive Impairment | Dementia, Vascular | Dementia, Mixed | Dementia Alzheimers | Mild Dementia | Dementia of Alzheimer Type | Dementia, Mild

United States
General Hospital of Ningxia Medical University

Recruiting

Chronotherapy for Radiotherapy of Glioma

To Determine Whether the Timing of Radiotherapy Has an Effect on Patient Outcomes

China
Karolinska Institutet

Recruiting

Optimization of Patients' Physical and Mental Status Prior to Colorectal Cancer Surgery (OPT)

Complication,Postoperative | ERAS

Sweden
Rush University Medical Center

Completed

Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers

CO2 Clearance | Mask Comfort | Rebreathing Exhaled Gas

United States
Azienda Policlinico Umberto I

Completed

Efficacy and Tolerability of α-galactosidase in Treating Gas-related Symptoms in Children

Gas Pain Related Intake
McGill University Health Centre/Research Institute...

Terminated

Effect of Palifermin on Skin Tumors in Patients Undergoing Bone Marrow Transplantation (Palifermin)

Skin Rash

Canada
Tyligand Bioscience (Shanghai) Limited

Recruiting

TSN222 in Subjects With Advanced Solid Tumors or Lymphomas

Has a Pathologically Documented Unresectable Locally Advanced or Metastatic Solid Tumor or Lymphoma

China
University Hospital, Rouen

Unknown

Detection of Circulating Tumor Cells for the Diagnostic of Pancreatic Adenocarcinoma. (CTC-Pancreas)

Pancreatic Adenocarcinoma | Circulating Tumor Cells | Circulating Tumor DNA (KRAS) | CA 19.9

France
Mitsubishi Tanabe Pharma America Inc.

Completed

Study to Assess Pharmacokinetics, Safety, and Tolerability of MT-7117 in Subjects With Normal and Impaired Hepatic Function

Mild and Moderate Hepatic Impairment

United States
XenoPort, Inc.

Recruiting

An Efficacy and Safety Evaluation of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS (RLS)

RLS

United States
MapKure, LLC

Recruiting

A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Colorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Australia, United States
Xynomic Pharmaceuticals, Inc.

Not yet recruiting

XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation (ENHANCE)

Melanoma | Cancer | Colorectal Cancer | Nonsmall Cell Lung Cancer | Thyroid Cancer | BRAF V600 Mutation
National and Kapodistrian University of Athens

Recruiting

Immunonutrition in ERAS Protocols in Gynecologic Oncology (NUTRIGO)

Gynecologic Cancer | Nutritional Deficiency | ERAS

Greece
Mackay Memorial Hospital
Bened Biomedical Co., Ltd.

Recruiting

Relationship Between Gut Microbiome, Probiotics, and Mild Cognitive Impairment

Mild Cognitive Impairment (MCI)

Taiwan

Clinical Trials on RAS and BRAF Wild-type

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