Clinical Trials on RLS

Total 307 results

Synapse Biomedical
Johns Hopkins University; Stanford University; University Hospitals Cleveland...

Unknown

Motor-Point Stimulation for Conditioning the Diaphragm of Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

United States, France
Charite University, Berlin, Germany

Terminated

Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Germany
Ono Pharmaceutical Co. Ltd

Completed

Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Belgium, France, Austria, Germany, Italy, Netherlands, Switzerland, United Kingdom
Institut de Recherche sur la Moelle épinière et...
Groupe Hospitalier Pitie-Salpetriere; Institut de Myologie, France; Association... and other collaborators

Recruiting

Atalante Exoskeleton in the Rehabilitation of Patients With Amyotrophic Lateral Sclerosis (EXALS)

ALS - Amyotrophic Lateral Sclerosis

France
Ludwig-Maximilians - University of Munich
Charité Universitätsmedizin, Department of Hematology, Oncology and Tumor...

Not yet recruiting

Centralized Tumour Board and Secondary Intervention Rate in mCRC

Metastatic Colorectal Cancer | Multidisciplinary Communication | RAS Mutation | Secondary Intervention
Charite University, Berlin, Germany
Max Planck Institute for Infection Biology

Completed

Safety and Tolerability of Anakinra in Combination With Riluzol in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS)

Germany
Charite University, Berlin, Germany

Completed

Olanzapine for the Treatment of Appetite Loss in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Germany
Mitsubishi Tanabe Pharma America Inc.

Completed

Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

United States, Canada, Japan, France, Germany, Italy
AB Science

Completed

Masitinib in Combination With Riluzole for the Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Spain
Eisai Co., Ltd.

Completed

A Study in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Japan
Barrow Neurological Institute
ALS Association; Muscular Dystrophy Association; Synapse Biomedical

Completed

Diaphragm Pacing System (DPS) In Participants With Amyotrophic Lateral Sclerosis (ALS) (DPS in ALS)

Amyotrophic Lateral Sclerosis (ALS)

United States
University Hospital, Limoges
Laboratoires NUTRICIA

Completed

Oral Nutritional Supplementation in Amyotrophic Lateral Sclerosis (ALS) Patients (NUTRALS)

Amyotrophic Lateral Sclerosis (ALS)

France
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Prognostic Value of a Diaphragmatic Endurance Test in Patients With Amyotrophic Lateral Sclerosis (SLA)

ALS (Amyotrophic Lateral Sclerosis)

France
University of Alberta
McGill University; University of Toronto; University of Calgary; Western University...

Completed

MRI Biomarkers in ALS

Amyotrophic Lateral Sclerosis | ALS | Motor Neuron Diseases

Canada
Yunxia Wang, MD
Western ALS Study Group

Completed

Trial of Safety and Efficacy of Rasagiline in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

United States, Canada
Red de Terapia Celular
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia and other collaborators

Unknown

Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis (TCIM/ELA)

ALS (Amyotrophic Lateral Sclerosis)

Spain
Kayseri Education and Research Hospital

Completed

Fetal Pulmonary Artery Acceleration to Ejection Time Ratio (PATET) in the Prediction of Subsequent Development of Respiratory Distress Syndrome (RDS)

RDS
University of Calgary
Hotchkiss Brain Institute, University of Calgary

Unknown

A Registry-Based Clinical Trial of Pimozide in Patients With Neuromuscular Junction Transmission Dysfunction Due to ALS

Amyotrophic Lateral Sclerosis (ALS)

Canada
Assistance Publique Hopitaux De Marseille

Unknown

Neuroinflammation in Amyotrophic Lateral Sclerosis - Mechanisms and Therapeutic Perspectives: a Translational Pilot Study Among ALS Patients

Amyotrophic Lateral Sclerosis (ALS)

France
US Department of Veterans Affairs
New York State Department of Health

Completed

A Clinical Demonstration of EEG Brain-computer Interface for ALS Patients (ALS)

ALS (Amyotrophic Lateral Sclerosis)

United States
Ono Pharmaceutical Co. Ltd

Completed

A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Belgium, France, Germany, Italy, Netherlands, Switzerland, United Kingdom
The Avicena Group

Unknown

Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS)

United States
Deciphera Pharmaceuticals LLC

Not yet recruiting

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

Melanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene Mutation

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Completed

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | RAS Wild Type

United States
Iron Horse Diagnostics, Inc.

Unknown

A Study to Evaluate the Performance of a Diagnostic Test in ALS

Amyotrophic Lateral Sclerosis (ALS)

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Unknown

A Programme for Amyotrophic Lateral Sclerosis Care in Europe (ALS-CarE)

ALS (Amyotrophic Lateral Sclerosis) | MND (Motor Neurone DIsease)

United Kingdom
University of Illinois at Chicago
University of Chicago

Active, not recruiting

Remotely Supervised tDCS for Slowing ALS Disease Progression

Amyotrophic Lateral Sclerosis (ALS)

United States
Washington University School of Medicine
Johns Hopkins University; Massachusetts General Hospital; Columbia University; UMC... and other collaborators

Completed

Understanding Clinical Phenotype and Collecting Biomarker Samples in C9ORF72 ALS

C9ORF72 Amyotrophic Lateral Sclerosis (ALS)

United States, Netherlands
EMD Serono
Merck KGaA, Darmstadt, Germany

Completed

Phase II Trial of Pimasertib Versus Dacarbazine in N-Ras Mutated Cutaneous Melanoma

N-Ras Mutated Locally Advanced or Metastasis Malignant Cutaneous Melanoma

United States, Sweden, Australia, France, Italy, South Africa, Spain, United Kingdom, Germany, Netherlands, Israel, New Zealand, Belgium, Switzerland
University Hospital, Lille
ApoPharma

Completed

Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients (SAFEFAIRALS)

ALS (Amyotrophic Lateral Sclerosis) | Iron Overload

France
Unity Health Toronto

Recruiting

Use of Gentle Synchronized Negative Pressure in Helping Babies Breathe (Neovest)

Respiratory Distress Syndrome | RDS of Prematurity | TTN | Respiratory Distress, Newborn

Canada
Tammie L. S. Benzinger, MD, PhD

Completed

F 18 T807 Tau PET Imaging in Familial Amyotrophic Lateral Sclerosis (T807ALS)

Amyotrophic Lateral Sclerosis (ALS)

United States
Intergroupe Francophone de Cancerologie Thoracique
Pfizer

Completed

Efficacy of Treatment Sequences in Patients With Non-small Cell Lung Cancer Receiving Lorlatinib (LORLATU)

ALK Gene Rearrangement Positive | Non-small Cell Lung Cancer Metastatic | ROS-1 Gene Rearrangement Positive

France
Erebouni Medical Center
Fisher and Paykel Healthcare

Completed

Effect of Cannula Size on Oxygen Saturation During Nasal High Flow Therapy in Newborns

TTN | RDS - Infants

Armenia
University of Oulu

Completed

Non-invasive Ventilation With Neurally Adjusted Ventilatory Assist Versus Nasal Continuous Airway Pressure in Premature Infants (NIV NAVA)

Respiratory Distress Syndrome (RDS) of Neonate

Finland
Second Affiliated Hospital, School of Medicine,...
Changxing People's Hospital

Recruiting

Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases

Unresectable Colon Cancer Peritoneal Metastases | PMMR/Ras/BRAF Wild-type

China
University of Florida

Completed

Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease (AIH in ALS)

Neuromuscular Diseases | Amyotrophic Lateral Sclerosis (ALS)

United States
Synapse Biomedical

Completed

Humanitarian Device Exemption Post-Approval Study of NeuRx Diaphragm Pacing System for Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS)

United States
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
RasCal Therapeutics, Inc.

Recruiting

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Glioblastoma | Pancreatic Cancer | Lung Cancer | Colon Cancer | Advanced Malignant Solid Neoplasm | RAS Mutation

United States
National Institute of Mental Health (NIMH)

Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Parkinson's Disease | Dementia | ALS | Alzheimer's Disease

United States
Barrow Neurological Institute
Arizona State University

Completed

Speech Analysis in ALS Patients

Amyotrophic Lateral Sclerosis | ALS | Lou Gehrig Disease

United States
Centre Leon Berard

Recruiting

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING) (TRacKING)

Cancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditions

France, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
Karolinska Institutet

Recruiting

Surfactant Administration by Insure or Thin Catheter (SAINT)

Analgesia | RDS of Prematurity | Surfactant Deficiency Syndrome Neonatal

Sweden
Hacettepe University

Completed

Premature Newborns Treated With Less Invasive Surfactant Administration Under Heated Humidified High-flow

Respiratory Disease | Newborn Rds

Turkey
Chiesi Farmaceutici S.p.A.

Terminated

A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional Administration (LISPAP)

Respiratory Distress Syndrome (RDS)

United States
Taipei Medical University Shuang Ho Hospital

Completed

Tamoxifen Treatment in Patients With Motor Neuron Disease

Amyotrophic Lateral Sclerosis | ALS Functional Ration Scale | TAR-DNA-binding Protein-43 | Tamoxifen | mTOR

Taiwan
Emory University
National Cancer Institute (NCI); GlaxoSmithKline; National Institutes of Health...

Active, not recruiting

Niraparib and Panitumumab in Patients With Advanced or Metastatic Colorectal Cancer (NIPAVect)

Microsatellite Stable | Stage IV Colorectal Cancer AJCC v8 | RAS Wild Type | MSI-H Colorectal Cancer | Metastatic Microsatellite Stable Colorectal Carcinoma | Advanced Microsatellite Stable Colorectal Carcinoma

United States
Assistance Publique - Hôpitaux de Paris
Groupe Hospitalier Pitie-Salpetriere

Terminated

ACE Inhibitors or ARBs Discontinuation in Context of COVID-19 Pandemic (ACORES-2)

History of Cardiovascular Disease Treated With RAS Blockers and With SARS-CoV-2 Infection

France
Hacettepe University

Completed

LUNG ULTRASONOGRAPHY DECREASES RADIATION EXPOSURE (LUDRE)

Pneumonia | Transient Tachypnea of the Newborn | Newborn Rds

Turkey

Clinical Trials on RLS

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bangladesh

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations