Clinical Trials on Rare Cancers

Total 179924 results

Jules Bordet Institute

Completed

Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers (MOMENTUM1)

Metastatic Colorectal Cancers | Metastatic Gastric Cancers | Metastatic Oesophageal Cancers | Metastatic Pancreatic Cancers | Metastatic Biliary Cancers | Metastatic Breast Cancers

Belgium
National Health Research Institutes, Taiwan
National Taiwan University Hospital; National Cheng-Kung University Hospital

Completed

Biweekly SOLAR, as First-line C/T in Pts With Gastric, Pancreatic and Biliary Cancers (SOLAR)

Gastric Cancer in Situ | Pancreatic Cancers | Biliary Cancers

Taiwan
Stanford University

Terminated

Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors

Head and Neck Cancer | Colorectal Neoplasms | Lung Cancer | Colon Cancer | Colonic Neoplasms | Head and Neck Cancers | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer | Colon/Rectal Cancer Colon Cancer | Colon/Rectal Cancer Rectal Cancer | Colon/Rectal Cancer Anal Cancer | Head and Neck Cancers Lip | Head... and other conditions

United States
Stanford University
The American Association of Physicists in Medicine

Terminated

Feasibility of Using Real-time Cine-MRI for Treating Moving & Deforming Tumors

Pancreatic Cancer | Lung Cancer | Liver Cancer | Hepatobiliary Cancers | Hepatobiliary Cancers Liver | Lung Cancer Non-Small Cell Cancer (NSCLC) | Lung Cancer Small Cell Lung Cancer (SCLC) | Hepatobiliary Cancers Hepatocellular Carcinoma (Hepatoma) | Hepatobiliary Cancers Gallbladder | Hepatobiliary Cancers...

United States
Stanford University
Caring for Carcinoid Foundation; GI Cancer Research Gift Fund

Withdrawn

Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers

Gastrointestinal Neoplasms | Pancreatic Cancer | Anal Cancer | Colon/Rectal Cancer | Hepatobiliary Cancers | Gastric (Stomach) Cancer | Gynecologic Cancers | Gastro-Esophageal(GE) Junction Cancer | Gynecologic Cancers Cervical Cancer | Gastrointenstinal Stromal Tumor (GIST) | Colon/Rectal Cancer Colon Cancer and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers

Small Bowel Cancers | Colorectal Cancers

United States
University of Colorado, Denver
National Cancer Institute (NCI); University of Kentucky; University of Louisville and other collaborators

Not yet recruiting

Precision Lung Cancer Survivorship Care Intervention (KYLEADSII)

Lung Cancer | Neoplasms, Lung | Pulmonary Neoplasms | Neoplasms, Pulmonary | Pulmonary Cancer | Cancer of Lung | Cancer, Lung | Cancer of the Lung | Pulmonary Neoplasm | Lung Cancers | Neoplasm, Pulmonary | Cancers, Lung | Cancer, Pulmonary | Cancers, Pulmonary | Pulmonary Cancers
Stanford University
GE Healthcare; Siemens Corporation, Corporate Technology

Terminated

Perfusion CT as a Predictor of Treatment Response in Patients With Hepatic Malignancies

Neuroendocrine Tumors | Colon Cancer | Colon/Rectal Cancer | Liver | Brain (Nervous System) Cancers | Hepatobiliary Cancers | Hepatocellular Carcinoma (Hepatoma)

United States
University Hospital, Rouen

Completed

Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in Early Onset Cancers With Sporadic or Hereditary Presentation (PANEL)

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Pediatric Cancers | Multiple Primary Malignant Tumours

France
Freenome Holdings Inc.

Recruiting

The Sanderson Study: A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening

Newly-diagnosed Cancers | Non-cancer Controls

United States
Health Science Center of Xi'an Jiaotong University

Recruiting

Efficacy and Safety of Involving Field Radiotherapy in the Oligo-lesions(Metastasis/Recurrent/Refractory) of Ovarian Cancer

Ovarian Cancer | Cancer of the Ovary | Ovarian Neoplasm | Ovary Cancer | Neoplasms, Ovarian | Ovary Neoplasms | Ovary Neoplasm | Cancer of Ovary | Cancer, Ovarian | Ovarian Cancers | Neoplasm, Ovarian | Neoplasm, Ovary | Neoplasms, Ovary | Cancer, Ovarian Stromal | Cancers, Ovary | Ovary Cancers | Cancers, Ovarian

China
Zhujiang Hospital

Recruiting

A Multicenter RCT Study of 3DV Technology in the Diagnosis and Treatment of PLC

Primary Liver Cancers

China
Stanford University

Completed

Cyberknife Precision Radiation Delivery System for Tumors of the Spine

Brain (Nervous System) Cancers | Spinal Cord Cancer

United States
Bold Therapeutics, Inc.

Active, not recruiting

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

Colorectal Cancer | Pancreatic Cancer | Cholangiocarcinoma | Gastric Cancers

Korea, Republic of, United States, Canada
Stanford University
Susan G. Komen Breast Cancer Foundation; Breast Cancer Research Foundation

Recruiting

Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples

Breast Cancer | Ovarian Cancer | Gynecologic Cancers | Ovarian/Peritoneal/Fallopian Cancer

United States
IGF Oncology, LLC

Completed

Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R

Melanoma | Breast Cancer | Brain Cancer | Head and Neck Cancers | Gastrointestinal Cancers | Gynecologic Cancers | Genitourinary Cancers | Thoracic Cancers

United States
Baskent University

Recruiting

Logotherapy Counseling Programme for Palliative Care Patients With Chronic Sorrow

Cancer | Palliative Care

Turkey
National Cancer Institute (NCI)

Terminated

Generation of Cancer Antigen-Specific T-cells From Human Induced Pluripotent Stem Cells (iPSC) for Research and Potential FutureTherapy

Melanoma | Breast Cancer | Pancreatic Cancer | Lung Cancer | Gastrointestinal Cancers

United States
Oncovir, Inc.
National Cancer Institute (NCI); University of Missouri-Columbia; Icahn School... and other collaborators

Completed

In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol® (Poly-ICLC)

Melanoma | Sarcoma | Head and Neck Cancer | Non-Melanoma Skin Cancers

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Johns Hopkins University; Swiss Cancer League

Completed

Transitoriness in Cancer Patients, Psychosocial Issues in Cancer Care

Lung Cancer | Gastrointestinal Cancers

United States
Duke University

Completed

Adaptive Pet Study

Head and Neck Cancers | Lung and Esophagus Cancers | Anal, Cervix, Vulvar, Vaginal, and Endometrium Cancers

United States
University of Bergen
Norwegian Extra Foundation for Health and Rehabilitation; Askøy Municipality

Completed

Cancer Rehabilitation in Primary Health Care

Cancer Survivors | All Cancers

Norway
Memorial Sloan Kettering Cancer Center
Joan Karnell Cancer Center at Pennsylvania

Active, not recruiting

A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer

Breast Cancer | Lung Cancer | Prostate Cancer | Gynecological Cancers | Lymphoma Cancer

United States
Jonsson Comprehensive Cancer Center

No longer available

68Ga DOTATATE PET/CT in Neuroendocrine Tumors (Expanded Access)

Neuroendocrine Tumors | Medullary Thyroid Cancer | Carcinoid Cancer | Cancers Expressing Somatostatin Receptors

United States
Seagen Inc.

Completed

A Study of Tucatinib (ONT-380) Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast Cancer

HER2 Positive Breast Cancers

United States, Canada
SOFIE

Recruiting

Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers (18F-FAPI-74 GI)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Cholangiocarcinoma | Pancreatic Ductal Adenocarcinoma | Gastrointestinal Cancers

United States
University of Colorado, Denver
National Cancer Institute (NCI)

Recruiting

A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image Quality

Prostate Cancer | Head and Neck Cancers | Upper Abdomen Cancers

United States
University Health Network, Toronto
Princess Margaret Hospital, Canada

Active, not recruiting

Integrated Molecular Profiling in Advanced Cancers Trial (IMPACT)

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Genitourinary Cancer | Rare Cancers | Gynecological Cancers | Pancreatobiliary Gastrointestinal Cancer | Upper Aerodigestive Tract Cancer | Melanoma Cancers | Unknown Primary Cancers

Canada
National Taiwan University Hospital

Unknown

Diagnosis of Oral Precancers and Cancers Using Optic Coherence Tomography

Oral Cancers

Taiwan
AstraZeneca

Active, not recruiting

A Phase 3b, Open-label, Multi-center Study on Durvalumab in Combination With Gemcitabine-based Chemotherapy as 1L Treatment for the Chinese Patients With Unresectable Biliary Tract Cancers (BTC) (TopDouble)

Biliary Tract Cancers

China
British Columbia Cancer Agency
BC Cancer Foundation

Recruiting

Personalized Oncogenomics (POG) Program of British Columbia

Advanced Cancers | Metastatic Cancers | Cancers That Cannot be Treated With Curative Intent

Canada
Henan Provincial People's Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety Study of Nab-Paclitaxel Combined With Cisplatin in Second or Later-Line Treatment in Advanced Biliary Tract Cancers

Advanced Biliary Tract Cancers

China
Centre Leon Berard
GlaxoSmithKline

Recruiting

PREventing Second Cancers With DOSTARlimab (PREDOSTAR)

Recurrent Cancer | Second Cancer | Primary Cancer

France
British Columbia Cancer Agency
Genome British Columbia; BC Cancer Foundation

Unknown

Real-world Clinical Effectiveness of Whole Genome and Transcriptome Analysis to Guide Advanced Cancer Care

Metastatic Cancer | Advanced Cancer | Cancers That Cannot be Treated With Curative Intent
German Cancer Research Center
German Consortium for Translational Cancer Research

Recruiting

Molecularly Aided Stratification for Tumor Eradication Research (NCT-MASTER)

Rare Cancers | Multiomics

Germany
Surface Oncology

Completed

Study of SRF231 in Patients With Advanced Solid and Hematologic Cancers

Hematologic Cancers | Advanced Solid Cancers

United States, Canada
Jazz Pharmaceuticals
BeiGene, Ltd.

Active, not recruiting

A Study of ZW25 (Zanidatamab) in Subjects With Advanced or Metastatic HER2-Amplified Biliary Tract Cancers (HERIZON-BTC-01)

HER2-amplified Biliary Tract Cancers

United States, Spain, United Kingdom, Korea, Republic of, Canada, China, Italy, Chile, France
Stanford University

Terminated

FNA Tumor Sampling for CD137 Modulation: A Pilot Study

Breast Cancer | Head and Neck Cancer | Non-Hodgkin Lymphoma | Colorectal Adenocarcinoma | Head and Neck Cancers

United States
AIO-Studien-gGmbH
Bristol-Myers Squibb

Completed

A Multicenter Open-label Phase II Trial to Evaluate Nivolumab and Ipilimumab for 2nd Line Therapy in Elderly Patients With Advanced Esophageal Squamous Cell Cancer (RAMONA)

Esophageal Cancer | Gastrooesophageal Cancer | Oesophageal Cancer | GastroEsophageal Cancer | Esophageal Cancers NOS | Oesophageal Cancer Metastatic | Esophageal Cancer Metastatic | Oesophageal Cancer Nos

Germany
TargetCancer Foundation
Foundation Medicine

Recruiting

TCF-001 TRACK (Target Rare Cancer Knowledge) Study (TRACK)

Cholangiocarcinoma | Cancer of Unknown Primary Site | Rare Cancers

United States
TScan Therapeutics, Inc.

Recruiting

A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors

Melanoma | Cervical Cancer | Head and Neck Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | HPV16 Related Cancers

United States
Jazz Pharmaceuticals
Quintiles, Inc.

Completed

A Study of Sativex® for Pain Relief in Patients With Advanced Malignancy. (SPRAY)

Pain | Cancer | Palliative Care

Spain, United Kingdom, United States, Canada, Poland, India, France, Czech Republic, Belgium, Romania, Chile, Finland, Germany, Italy, Mexico, South Africa
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors

Lung Cancer | Metastatic Cancer | Bladder Cancer | Renal Cancer | Melanoma Cancer | Head/Neck Cancers

United States
University Health Network, Toronto

Active, not recruiting

A Study of Investigational Drug CFI-402257 in Patients With Advanced Solid Tumors

Breast Cancer | Advanced Solid Cancers

Canada
Institut Cancerologie de l'Ouest

Completed

Medico-economic Evaluation Comparing Intensity-Modulated Radiation Therapy (IMRT) Performed by Helical Tomotherapy and Dynamic Arc Therapy in Prostate, Cervical and Anal Canal Cancers (RCMI PELVIS)

Cervical Cancer | Prostate Cancer | Anal Canal Cancers

France
Chinese University of Hong Kong

Completed

Surgery or Chemoradiation for Esophageal Cancer

Esophageal Cancers
Dana-Farber Cancer Institute
National Palliative Care Research Center (NPCRC)

Recruiting

STAMP+CBT mHealth for Cancer Pain

Advanced Cancer | Palliative Care | Active Cancer | Active Cancer Treatment | Chronic Pain Due to Cancer

United States
Zagazig University

Completed

Intralesional Versus Intramuscular Methotrexate for Non-melanoma Skin Cancers

Non-melanoma Skin Cancers

Egypt
Nantes University Hospital

Active, not recruiting

Status of Superficial Esophageal Cancers Treated by Endoscopy "OESOFARE" (OESOFARE)

Superficial Esophageal Cancers

France
MedImmune LLC

Completed

A Phase 1/2 Study of MEDI4276 in Adults Subjects With Select HER2-expressing Advanced Solid Tumors. (MEDI4276)

HER2 Expressing Breast or Gastric/Stomach Cancers

United States

Clinical Trials on Rare Cancers

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Lithuania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations