Clinical Trials on Recent HIV-1 Infection in Canada

Total 482 results

Bristol-Myers Squibb

Completed

Study of a New Protease Inhibitor, BMS-232632, in Combination With Other Anti-HIV Drugs

HIV Infections

United States, Canada
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Active, not recruiting

Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine From Current Antiretroviral Regimen in Virologically Suppressed HIV-1-infected Adults

HIV Infections | Infection, Human Immunodeficiency Virus

Germany, Spain, France, United States, Canada, Australia, Korea, Republic of, Italy, South Africa, Russian Federation, Argentina, Mexico, Sweden
F-star Therapeutics, Inc.
PRA Health Sciences

Terminated

Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor

Hepatitis B | Hepatitis B, Chronic | HBV

Canada, United Kingdom
LMC Diabetes & Endocrinology Ltd.

Completed

Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population (PEDAL)

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Onychomycosis | Foot Deformities | Neuropathy, Diabetic | Foot Ulcer, Diabetic | Hyperkeratosis | Onychauxis

Canada
Bristol-Myers Squibb

Completed

Safety, Tolerability and Pharmacokinetics of Efavirenz in HIV-Infected Children

HIV Infections

Thailand, Mexico, Argentina, Colombia, Panama, South Africa
University Paris 7 - Denis Diderot
University of Sydney; Université de Montréal; Center of treatment HIV/Aids-São...

Completed

International Validation of a Sexual Quality of Life Questionnaire Specific to HIV and Hepatitis C (PROQOL-SexLife) (SexLife)

Hepatitis C | Sexual Dysfunction | HIV

France, Australia, Brazil, Canada
Glaxo Wellcome

Completed

The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States, Canada, Puerto Rico
McGill University
ResMed; VitalAire

Unknown

Obstructive Sleep Apnea, CPAP Treatment & Cognitive Ability in HIV

Obstructive Sleep Apnea | Cognitive Change | Hiv

Canada
Amgen

Completed

A Randomized, Controlled, Multicenter Trial of Filgrastim (Recombinant-Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF) for the Prevention of Grade 4 Neutropenia in Patients With HIV Infection.

HIV Infections | Cytopenias

United States, Canada
Roche Global Development

Completed

A Study of Two Forms of Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Abbott

Completed

Study of Lopinavir/Ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice Daily Administration, When Coadministered With Nucleoside Reverse Transcriptase Inhibitors in Antiretroviral Naive Human Immunodeficiency Virus Type 1 Infected Subjects

Human Immunodeficiency Virus Infections

United States, Australia, Belgium, Canada, Czech Republic, France, Germany, Greece, Ireland, Italy, Netherlands, Poland, Puerto Rico, Russian Federation, Singapore, Spain, Switzerland, Taiwan, United Kingdom
Glaxo Wellcome

Completed

A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine

HIV Infections | Toxoplasmosis, Cerebral

United States, Canada
ViiV Healthcare
GlaxoSmithKline

Terminated

Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults

Infection, Human Immunodeficiency Virus

United States, France, Germany, Canada, Spain, United Kingdom, Mexico, Italy, Argentina, Chile, South Africa, Poland
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

A Trial Comparing GSK1349572 50mg Plus Abacavir/Lamivudine Once Daily to Atripla (Also Called The SINGLE Trial)

Infection, Human Immunodeficiency Virus I

United States, Spain, Germany, Australia, Canada, Belgium, Denmark, Netherlands, United Kingdom, France, Italy, Romania
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

A Study to Assess Dolutegravir in HIV-infected Subjects With Treatment Failure on an Integrase Inhibitor Containing Regimen. (VIKING-3)

Infection, Human Immunodeficiency Virus

United States, Spain, France, Canada, Portugal, Italy, Belgium
Inovio Pharmaceuticals

Completed

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

Anal Neoplasm

United States, Canada
ViiV Healthcare
GlaxoSmithKline; PPD

Completed

A Phase IIIb Study of the Safety, Efficacy, and Tolerability of Switching to a Fixed-dose Combination of Abacavir/Dolutegravir/ Lamivudine From Current Antiretroviral Regimen

Infection, Human Immunodeficiency Virus

United States, Canada, Puerto Rico
Bristol-Myers Squibb

Completed

Evaluation of an Anti-HIV Drug Combination That Includes a Coated Form of Didanosine (ddI EC) Compared to a Typical Anti-HIV Drug Regimen

HIV Infections

United States, Canada
ViiV Healthcare
GlaxoSmithKline; PPD

Recruiting

A Study to Evaluate the Efficacy, Safety, Participant Choice and Preference of an Oral Once-daily Regimen or a Long-acting Injectable Regimen Every Two Months for Treatment of Human Immunodeficiency Virus (HIV-1) in Adults Who Have Not Previously Taken Antiretroviral Therapy (VOLITION)

HIV Infections

United States, Italy, Spain, Argentina, Germany, France, Canada, Chile, Puerto Rico
Bristol-Myers Squibb

Completed

Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome

HIV-Associated Lipodystrophy Syndrome

Spain, Italy, United States, Canada, France, Mexico, United Kingdom, Poland, Germany
Carmen Hidalgo Tenorio
Gilead Sciences

Completed

Study of Bictegravir/Emtricitavine/Tenofovir Alafenamide in HIV-1 Infected naïve Patients Using Test and Treat Stategy Rapid-initiation Model of Care: BIC-NOW Clinical Trial (BIC-NOW) (BIC-NOW)

HIV Infections

Spain
AbbVie

Completed

A Study of of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus (HCV) Genotype 5 or 6 Infection (ENDURANCE-5 6)

Hepatitis C Virus (HCV)

United States, Australia, Belgium, Canada, France, New Zealand, Singapore, South Africa, Vietnam
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Optimized Background Therapy Versus Optimized Background Therapy Alone for the Treatment of HIV-1 Infected Subjects (MOTIVATE 1)

HIV Infections

United States, Canada
Bristol-Myers Squibb

Completed

Comparison of Two Anti-HIV Regimens That Include One of Two Forms of Didanosine (ddI)

HIV Infections

United States, Canada
Glaxo Wellcome

Completed

The Safety and Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Taken AZT

HIV Infections

United States, Canada, Puerto Rico
Hoffmann-La Roche
Trimeris

Completed

A Study Comparing the Efficacy and Safety of Once-Daily Fuzeon (Enfuvirtide) Dosing Versus the Currently Recommended Twice-Daily Dosing in Human Immunodeficiency Virus-Type 1 (HIV-1) Infected Patients

HIV Infections

United States, Canada, Puerto Rico
Radboud University Medical Center
Bristol-Myers Squibb; Merck Sharp & Dohme LLC; Gilead Sciences; ViiV Healthcare; Janssen... and other collaborators

Recruiting

Pharmacokinetics of Antiretroviral Agents in HIV-infected Pregnant Women. (PANNA)

HIV Infections

Germany, United Kingdom, Netherlands, Belgium, Ireland, Italy, Spain
Keimyung University Dongsan Medical Center

Completed

Influence of Remifentanil on Postoperative Sore Throat in Patients Undergoing General Anesthesia

Hip Arthroplasty

Korea, Republic of
Hospital de Granollers

Completed

Study to Evaluate Changes in CD4 on Replacing TDF With ABC or DDI+TDF With ABC+3TC

HIV Infections

Spain
Hoffmann-La Roche

Completed

A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral Drugs

HIV Infections

Canada, United States
Hoffmann-La Roche

Completed

Safety and Effectiveness of Adding Saquinavir (FORTOVASE) in Soft Gel Capsule Form to an Anti-HIV Drug Combination in HIV-Infected Patients

HIV Infections

United States, Canada, Puerto Rico
AbbVie

Active, not recruiting

Study to Evaluate Adverse Events and Change in Disease Activity in Adult and Adolescent Participants With Acute Hepatitis C Virus (HCV) Infection on Treatment With Oral Tablets of Glecaprevir (GLE)/Pibrentasvir (PIB)

Hepatitis C Virus (HCV)

United States, Australia, Austria, Canada, France, Germany, Italy, Spain
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la...

Completed

Antiretroviral Treatment Simplification Study With Efavirenz + Abacavir + 3TC Once Daily

HIV Infections

Spain
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized Trial of the Efficacy and Safety of a Strategy of Starting With Nelfinavir Versus Ritonavir Added to Background Antiretroviral (AR) Nucleoside Therapy in HIV-Infected Individuals With CD4+ Cell Counts Less Than or Equal to 200/mm3

HIV Infections

United States, Canada
Glaxo Wellcome

Completed

A Comparison of Lamivudine and Zidovudine, Used Alone and Together, in HIV-Infected Patients Who Have Not Used Zidovudine in the Past

HIV Infections

United States, Canada, Puerto Rico
ViiV Healthcare
Janssen, LP

Completed

Phase 2b, Open-label, Multicenter, Rollover Study to Assess Antiviral Activity and Safety of Long-acting (LA) Cabotegravir (CAB) Plus LA Rilpivirine (RPV), Administered Every 2 Months (Q2M), in Human Immunodeficiency Virus (HIV)-Positive Participants From the LATTE Study

HIV Infections

United States, Canada
Hoffmann-La Roche

Completed

A Study to Evaluate the Safety and Efficacy of Adding Enfuvirtide to Oral Highly Active Antiretroviral Therapy (HAART) in Human Immunodeficiency Virus (HIV) Patients With Prior Treatment Experience (INTENSE)

HIV Infections

France, Germany, Spain, Italy, United States, Switzerland, Netherlands, Mexico, Canada, Israel
Janssen Sciences Ireland UC

Completed

A Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed Dose Combination (FDC) Versus a Regimen Consisting of Darunavir/Cobicistat FDC With Emtricitabine/Tenofovir Disoproxil Fumarate FDC in Treatment-naive HIV Type 1 Infected Subjects

Immunodeficiency Virus Type 1, Human

United States, France, Poland, United Kingdom, Belgium, Germany, Spain, Canada, Russian Federation, Puerto Rico
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la...

Completed

Study to Evaluate the Effectiveness of ABC+3TC +EFV in Once-Daily Regimens Versus KLT in Twice-Daily Regimens in Naive HIV Patients

HIV Infections

Spain, Italy
Hoffmann-La Roche

Completed

A Study to Compare Two Anti-HIV Drug Combinations

HIV Infections

Canada, United States, Puerto Rico
Kirby Institute

Completed

MARCH Renal Substudy (MARCHrenal)

Proteinuria | HIV

Canada, Australia, Germany, Argentina, Japan, Thailand, United Kingdom, Mexico
Glaxo Wellcome

Completed

A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States, Canada
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Completed

Bone Mineral Density in Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Adult Subjects Switching From a Tenofovir Regimen to a Dolutegravir Plus Rilpivirine Regimen

HIV Infections

Spain, United States, Canada, Belgium, United Kingdom, Argentina
Boehringer Ingelheim

Completed

Pharmacokinetics and Safety Study of Tipranavir in Combination With Low Dose Ritonavir in Human Immunodeficiency Virus (HIV)-Infected Children

HIV Infections

United States, Argentina, Brazil, Canada, France, Germany, Italy, Mexico, Puerto Rico, Spain
National Institute of Allergy and Infectious Diseases...

Completed

Effects of Anti-HIV Therapy on Nervous System Function

HIV Infections

United States, Brazil, Australia, Thailand, Canada
Bristol-Myers Squibb

Completed

Safety and Effectiveness of a New Protease Inhibitor, BMS-232632, in HIV-Positive Patients Who Have Received Previous Treatment

HIV Infections

United States, France, Canada, Italy, Germany
Hoffmann-La Roche
Trimeris

Completed

T-20 With Anti-HIV Combination Therapy for Patients With Prior Anti-HIV Drug Treatment and/or Drug Resistance to Each of the Three Classes of Approved Anti-HIV Drugs

HIV Infections

United States, Canada
Nestlé
Puerta de Hierro University Hospital; University of Navarrra Hospital (Clinica... and other collaborators

Completed

Human Milk Oligosaccharides (HMOs) Post-market Study on Infants (NEHMO)

Growth | Tolerance | Adverse Event | Disorder of Intestine | Disorder Lung

Spain
ViiV Healthcare
GlaxoSmithKline

Recruiting

VH4524184 Proof-of-Concept in Treatment-Naïve Adults Living With HIV-1

HIV Infections

United States, Spain, Canada, Italy, Argentina, Mexico
National Institute of Allergy and Infectious Diseases...
Community Programs for Clinical Research on AIDS

Completed

Collection of Blood Samples From SMART Study Participants for Future Genetic Studies

HIV Infections

United States, New Zealand, Australia, Japan, American Samoa, Belgium, Canada, Chile, Denmark, Finland, Gambia, Germany, Morocco, Poland, Portugal, Uruguay

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