Clinical Trials on Rectal Cancer, Adenocarcinoma in Canada

Total 8384 results

Vaccinex Inc.
Huntington Study Group

Completed

A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi (SIGNAL-HD)

Huntington's Disease

United States, Canada
Washington University School of Medicine
National Institute on Aging (NIA); Alzheimer's Association; Eisai Inc.; Accelerating...

Recruiting

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, Argentina, Australia, Colombia, Netherlands, Puerto Rico, Spain, United Kingdom, France, Ireland, Mexico, Brazil, Japan, Germany
Incyte Corporation
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)

Head and Neck Cancer

Canada, Spain, Korea, Republic of, United States, Austria, Japan, United Kingdom, Taiwan, Italy, Hungary, Australia, Turkey, Poland, Portugal
Sumitomo Pharma America, Inc.

Terminated

A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.

Depressive Episodes, Bipolar I Depression

United States, Bulgaria, Japan, Romania, Canada, Slovakia
Centre Hospitalier Universitaire de Besancon
European Network of Gynaecological Oncological Trial Groups (ENGOT); ARCAGY...

Recruiting

International Validation Study of Sentinel Node Biopsy in Early Cervical Cancer (SENTICOLIII)

Cervical Cancer

Spain, France, Germany, Czechia, Switzerland, China, Japan, Brazil, Italy, Canada, India, Norway, Slovakia
Karyopharm Therapeutics Inc
GOG Foundation; Israeli Society of Gynecologic Oncology; Belgium and Luxembourg... and other collaborators

Active, not recruiting

Maintenance With Selinexor/Placebo After Combination Chemotherapy in Participants With Endometrial Cancer [SIENDO] (ENGOT-EN5)

Endometrial Cancer

United States, China, Israel, Spain, Belgium, Germany, Greece, Czechia, Italy, Canada
AbbVie

Terminated

An Extension Study of ABBV-8E12 in Early Alzheimer's Disease (AD)

Alzheimer's Disease

United States, Australia, Belgium, Canada, Denmark, Finland, Italy, New Zealand, Spain, Sweden
Idorsia Pharmaceuticals Ltd.

Completed

Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia Disorder

Insomnia Disorder

United States, Germany, Australia, Canada, Denmark, Italy, Poland, Serbia, Spain, Switzerland
Allergan

Terminated

OnabotulinumtoxinA for the Treatment of Urinary Incontinence Due to Overactive Bladder in Pediatric Patients (12 to 17)

Urinary Incontinence | Urinary Bladder | Overactive

United States, Australia, Belgium, Canada, Czechia, France, Germany, Italy, Netherlands, Norway, Poland, South Africa, United Kingdom
OPKO Health, Inc.
Elan Pharmaceuticals

Terminated

A 36-Week Safety Extension Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease

Alzheimer's Disease

United States, Canada, Spain, United Kingdom
Alzheon Inc.

Enrolling by invitation

Long-term Extension of Phase 3 Study of ALZ- 801 in APOE4/4 Early AD Subjects (APOLLOE4-LTE)

Early Alzheimer's Disease

United States, Spain, Canada, Netherlands, Czechia, United Kingdom, France, Germany, Iceland
EndoCeutics Inc.

Completed

Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD)

Hypoactive Sexual Desire Disorder

United States, Canada
Takeda

Completed

Vortioxetine (Lu AA21004) 10 and 20 mg for Treatment of Major Depressive Disorder With Sexual Dysfunction

Treatment Outcome

United States, Canada
Cephalon

Completed

Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy

Narcolepsy

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Radiation... and other collaborators

Completed

Talc in Treating Patients With Malignant Pleural Effusion

Metastatic Cancer

United States, Canada
Washington University School of Medicine
Hoffmann-La Roche; Genentech, Inc.; National Institute on Aging (NIA); Alzheimer...

Suspended

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation (DIAN-TU)

Dementia | Alzheimers Disease | Alzheimers Disease, Familial

United States, Canada, Italy, France, Spain, Ireland, Argentina, Australia, Colombia, Germany, Mexico, Netherlands, Puerto Rico, United Kingdom
AstraZeneca

Completed

A Phase III Trial of ZD4054 (Zibotentan) (Endothelin A Antagonist) in Hormone Resistant Prostate Cancer With Bone Metastases (ENTHUSE M1)

Prostate Cancer

Sweden, United States, Brazil, Czech Republic, France, Russian Federation, United Kingdom, Germany, China, Hungary, Poland, Finland, Netherlands, Mexico, Hong Kong, Australia, Belgium, Canada, Denmark, Portugal, South Africa, Korea... and more
University College, London
CHDI Foundation, Inc.

Recruiting

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease (HDClarity)

Huntington's Disease

United States, United Kingdom, France, Canada, Germany, Italy, Spain, New Zealand, Poland
Teva Branded Pharmaceutical Products R&D, Inc.
Nuvelution TS Pharma, Inc.

Completed

Alternatives for Reducing Tics in Tourette Syndrome (TS): A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Tourette Syndrome in Children and Adolescents (ARTISTS1)

Tourette Syndrome

United States, Canada, Denmark, Russian Federation, Serbia, Spain
NCIC Clinical Trials Group

Completed

Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer

Pancreatic Cancer

United States, Canada, Australia, Singapore, Belgium, United Kingdom, Israel, New Zealand, China, Germany, Brazil, Poland, Italy, Argentina, Romania, Greece, Chile, Hong Kong, Mexico
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Metastatic Cancer | Radiation Toxicity | Cognitive/Functional Effects

United States, Canada
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (TRANSFORM-1)

Treatment-resistant Depression

United States, France, Belgium, Mexico, Canada, Brazil, Estonia, Hungary, Slovakia
Bayer

Completed

A Phase III Randomized, Double-blind, Placebo Controlled Trial Comparing the Efficacy of Gemcitabine, Cisplatin and Sorafenib to Gemcitabine, Cisplatin and Placebo in First-Line Treatment of Patients With Stage IIIb With Effusion and Stage IV Non-Small Cell Lung Cancer (NSCLC) (NEXUS)

Carcinoma, Non-Small-Cell Lung

Belgium, Spain, France, Switzerland, Greece, Italy, Hungary, Canada, Netherlands, United Kingdom, Austria, China, Israel, Mexico, Germany, Brazil, Finland, Cyprus
Hoffmann-La Roche

Completed

APPROACH Study: Quality of Life and Outcomes Assessment in Participants With Chronic Hepatitis C (CHC) Treated With Pegylated Interferon (PEG-IFN) Alfa-2a and Ribavirin

Hepatitis C, Chronic

Canada
Holland Bloorview Kids Rehabilitation Hospital
The Hospital for Sick Children

Recruiting

Cerebral Palsy Hip Outcomes Project - International Multi-centre Study

Cerebral Palsy

Denmark, Canada, United States, Australia, Israel, Korea, Republic of, New Zealand, Poland, Sweden, United Kingdom
Astellas Pharma Inc

Completed

A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)

Ovarian Cancer | Solid Tumors

United States, United Kingdom, Australia, Canada, Switzerland, Czechia, Italy, Poland, Romania, Russian Federation
AstraZeneca
RTI Health Solutions; A+A Healthcare Marketing Research; Freelance CRA (FCRA)

Completed

OSCA - Olaparib Standard of CAre Study (OSCA)

Platinum-sensitive Recurrent Serous Ovarian Cancer

France, Italy, Korea, Republic of, Spain, United Kingdom, Germany, Belgium, Israel, Portugal, Netherlands, Switzerland, Canada, Australia
Boehringer Ingelheim

Completed

Nintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1)

Colorectal Neoplasms

United States, Argentina, Australia, Austria, Belgium, Canada, Czechia, Denmark, France, Germany, Hong Kong, Israel, Italy, Japan, Korea, Republic of, Mexico, Netherlands, Poland, Portugal, Russian Federation, Spain, Sweden, Taiwan, T... and more
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Concomitant Use of PriLigy in Men Treated for Erectile Dysfunction (COUPLE)

Sexual Dysfunction | Erectile Dysfunction

France, Poland, United States, Belgium, Mexico, Malaysia, Canada, Taiwan, Korea, Republic of, Russian Federation, Argentina, Australia, United Kingdom
GlaxoSmithKline
PPD

Completed

4 Week Correction Study in Subjects With Anemia Associated With Chronic Kidney Disease Who Are Not Undergoing Dialysis

Anaemia

United States, Canada, Germany
Pfizer
GlaxoSmithKline

Completed

Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric Disorders (EAGLES)

Smoking Cessation

United States, Spain, Germany, Canada, South Africa, Finland, Denmark, Australia, Brazil, Bulgaria, Chile, Mexico, New Zealand, Russian Federation, Slovakia, Argentina
Janssen Research & Development, LLC

Completed

Study of Paliperidone Palmitate 3 Month and 1 Month Formulations for the Treatment of Patients With Schizophrenia

Schizophrenia

France, United States, China, Spain, Argentina, Mexico, Portugal, Bulgaria, Germany, Poland, Russian Federation, Ukraine, Japan, Greece, Taiwan, Korea, Republic of, Canada, Czech Republic, Brazil, Hungary, Austria, Sweden, Romania, Sl... and more
Incyte Corporation

Terminated

A Phase 2 Study of the IDO Inhibitor Epacadostat Versus Tamoxifen for Subjects With Biochemical-recurrent-only EOC, PPC or FTC Following Complete Remission With First-line Chemotherapy

Ovarian Cancer | Genitourinary (GU) Tumors

Ukraine, United Kingdom, United States, Australia, Canada, Russian Federation
vTv Therapeutics

Terminated

2-Year Extension Study of Azeliragon in Subjects With Alzheimer's Disease (STEADFAST Extension)

Alzheimer's Disease

United States, Canada
AstraZeneca
European Network of Gynaecological Oncological Trial Groups (ENGOT); Myriad... and other collaborators

Active, not recruiting

Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients (DUO-O)

Advanced Ovarian Cancer

Canada, Denmark, Germany, Italy, Spain, United States, Belgium, Poland, France, Korea, Republic of, Brazil, Hungary, Japan, Peru, Turkey, China, Austria, Bulgaria, Finland, Romania
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat in Non-Dialysis Subjects Evaluating Hemoglobin (Hgb) and Quality of Life (ASCEND-NHQ)

Anaemia

United States, Canada, France, Russian Federation, Spain, Australia, United Kingdom, Romania, Brazil, Korea, Republic of, Italy, Poland, Argentina, Mexico
Boehringer Ingelheim

Completed

Long-term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe Restless Legs Syndrome (RLS)

Restless Legs Syndrome

Austria, Belgium, Finland, Germany, Ireland, Netherlands, Slovakia, Spain, United Kingdom
Frederick Schmitt
National Cancer Institute (NCI); National Institute on Aging (NIA)

Completed

Prevention of Alzheimer's Disease by Vitamin E and Selenium (PREADVISE)

Alzheimer Disease

United States, Canada, Puerto Rico
National Cancer Institute (NCI)
Karolinska Institutet; Vanderbilt University Medical Center, USA; New England... and other collaborators

Terminated

Helicobacter Pylori Genome Project (HpGP)

Gastric Cancer | Intestinal Metaplasia | Non-Atrophic Gastritis

Spain, Lithuania, Taiwan, Singapore, Argentina, Korea, Republic of, Sweden, Canada, United States, Peru, Puerto Rico, Mexico, Chile, Turkey, Belgium, Kenya, Malaysia, Vietnam, Colombia, Israel, Brazil, Nepal, Switzerland, Japan, Congo,... and more
GlaxoSmithKline

Completed

Fluticasone Propionate/Salmeterol Combination 250/50 DISKUS in the Exercise Endurance Time in Patients With Chronic Obstructive Pulmonary Disease (ESWT)

Pulmonary Disease, Chronic Obstructive

Canada, United States
Shire

Completed

Tolerability and Efficacy of AM and PM Once Daily Dosing With Extended-release Guanfacine Hydrochloride in Children 6-12 With Attention-Deficit/Hyperactivity Disorder (ADHD) (The ADHD Tempo Study)

Attention-Deficit/Hyperactivity Disorder

United States, Canada
Alector Inc.
AbbVie

Active, not recruiting

A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease (INVOKE-2)

Alzheimer Disease

United States, Spain, France, Germany, Australia, Canada, Poland, Italy, Argentina, Netherlands, United Kingdom, New Zealand
TauRx Therapeutics Ltd

Completed

Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment

Alzheimer Disease

United States, Spain, Poland, Belgium, France, United Kingdom, Italy, Canada
Otsuka Pharmaceutical Development & Commercialization...

Completed

Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type

Alzheimer Disease

United States
Biohaven Pharmaceuticals, Inc.

Recruiting

Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder

Canada, Spain, United States, China, Italy, Netherlands, United Kingdom, Puerto Rico
Alzheimer's Disease Cooperative Study (ADCS)
National Institute on Aging (NIA); Northern California Institute of Research...

Completed

Alzheimer's Disease Neuroimaging Initiative Grand Opportunity (ADNI-GO)

Mild Cognitive Impairment | Alzheimer's Disease

United States, Canada
USRC Kidney Research
Akebia Therapeutics Inc.

Completed

Auryxia (Ferric Citrate) Therapy for In-Center and Home Dialysis Participants (IMPACT)

Renal Insufficiency | Hyperphosphatemia | Anemia, Iron Deficiency

United States
Takeda

Terminated

Health-Related Quality of Life in Crohn's Disease Participants With Complex Perianal Fistula Before and After Treatment (CALYPSO)

Gastrointestinal Diseases | Intestinal Diseases | Crohn Disease | Inflammatory Bowel Disease

Spain
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer

Head and Neck Cancer | Skin Reactions Secondary to Radiation Therapy

United States, Canada
Pfizer

Completed

Trial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine.

Colorectal Neoplasms

Australia, Canada, United States, New Zealand

Clinical Trials on Rectal Cancer, Adenocarcinoma in Canada

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