Clinical Trials on Rectal Neoplasms

Total 178383 results

QIAGEN Gaithersburg, Inc
Amgen

Recruiting

Therascreen® KRAS RGQ PCR Kit

Colo-rectal Cancer

United Kingdom
National Cancer Institute, Egypt

Recruiting

Reversal of a Defunctioning Ileostomy 3 Weeks After the Index Operation, RCT

Colo-rectal Cancer

Egypt
Seoul National University Hospital

Recruiting

Comparison Between Tailored Surgery Versus Total Mesorectal Excision in ycT2-3N0M0

Rectal Cancer, Adenocarcinoma

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts

Colo-rectal Cancer

China
Shanghai Zhongshan Hospital

Recruiting

Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer

Colo-rectal Cancer

China
Niguarda Hospital

Completed

Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal Cancer (NO-CUT)

Colo-rectal Cancer

Italy
George Albert Fisher
Bristol-Myers Squibb

Terminated

A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer

Rectal Cancer | Colo-rectal Cancer

United States
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

A Prospective Phase II Randomized Clinical Trial of Preoperative Chemotherapy Combined With Short-course Radiotherapy Versus Conventional Neo-adjuvant Therapy for Locally Advanced Rectal Cancer Implemented by MDT

Rectal Cancer, Radiotherapy
li xiong

Suspended

Safety and Efficiency of Photodynamic Therapy for Rectal Cancer (PDT-R-01)

Advanced Rectal Cancer

China
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Programs to Support You During Chemotherapy (Pro-You) (Pro-You)

Fatigue | Depressive Symptoms | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Psychosocial Effects of Cancer and Its Treatment | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon... and other conditions

United States
Jules Bordet Institute
University Hospital, Ghent

Completed

Comparing Hepatic Intra-arterial Injection of Yttrium-90 Microspheres Versus Fluorouracil (5FU) in Colorectal Cancer Metastatic to the Liver Only

Colorectal Neoplasm | Secondary Malignant Neoplasm of Liver

Belgium
Imperial College London

Recruiting

Anal Intraepithelial Neoplasia and Anal Squamous Cell Carcinoma

Anal Cancer | Anal Squamous Intraepithelial Neoplasia

United Kingdom
University Medical Center Groningen

Not yet recruiting

Evaluating PD-1/PD-L1 in Locally Advanced Rectal Cancer by Quantitative Fluorescence Molecular Endoscopy (PREDICT)

Locally Advanced Rectal Carcinoma

Netherlands
University of Hull
Hull University Teaching Hospitals NHS Trust

Not yet recruiting

Exercise for Improving Radiotherapy Efficacy in Rectal Cancer

Locally Advanced Rectal Carcinoma
Wuhan Union Hospital, China
Renmin Hospital of Wuhan University

Recruiting

Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study

Locally Advanced Rectal Cancer

China
Beijing Friendship Hospital
Peking Union Medical College Hospital

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
Tehran University of Medical Sciences

Not yet recruiting

Comparison of the Clinical Response of Total Neoadjuvant Treatment of Two Methods of Long-term or Short-term Chemoradiotherapy in Rectal Cancer (TEHRAN)

Locally Advanced Rectal Carcinoma
JIN JING

Not yet recruiting

Assess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC（AK104-IIT-13） (AK104-IIT-13)

Locally Advanced Rectal Cancer
Shenzhen People's Hospital
Sixth Affiliated Hospital, Sun Yat-sen University; The University of Hong Kong-Shenzhen...

Recruiting

Neoadjuvant Cadonilimab Plus Chemotherapy Following Short-Course Radiotherapy in Locally Advanced Rectal Cancer (NeoCaCRT)

Locally Advanced Rectal Carcinoma

China
National Cancer Center Hospital East
Japan Agency for Medical Research and Development

Recruiting

Total Neoadjuvant Therapy of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer (ENSEMBLE) (ENSEMBLE)

Locally Advanced Rectal Cancer

Japan
Fudan University

Recruiting

The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Early Rectal Cancer (TORCH-E） (TORCH-E)

Early Low Rectal Cancer

China
Korean Cancer Study Group

Not yet recruiting

Gut Microbiome and Its Immune Modulation in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer
Yonsei University

Not yet recruiting

Development of a Genome-based Platform for Personalized Treatment in Locally Advanced Rectal Cancer Patients

Locally Advanced Rectal Cancer

Korea, Republic of
Fudan University

Recruiting

Short-course Radiotherapy Based TNT Combined With PD-1 Inhibitor for Locally Advanced Rectal Cancer (TORCH)

Locally Advanced Rectal Cancer

China
Montreal General Hospital

Recruiting

The Impact of Physical Exercise on Sleep in Colorectal Cancer Patients During Prehabilitation Period

Surgery | Colo-rectal Cancer

Canada
Thomas Jefferson University

Completed

Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery?

Anesthesia | Colo-rectal Cancer

United States
Prof. Dr. med. Claus Rödel

Active, not recruiting

Short RT Versus RCT,Followed by Chemo.and Organ Preservation for Interm and High-risk Rectal Cancer Patients

Rectal Cancer Stage III

Germany
Universitätsklinikum Hamburg-Eppendorf
Servier Affaires Médicales; Clinical Trial Center North (CTC North GmbH & Co...

Terminated

Evaluating Trifluridine/Tipiracil Based Chemoradiation in Locally Advanced Rectal Cancer - The Phase I/II TARC Trial

Locally Advanced Rectal Cancer

Germany
Taichung Veterans General Hospital

Completed

Using Artificial Intelligence to Predict Rectal Cancer Outcomes

Rectal Cancer Stage III

Taiwan
National Cancer Institute, Egypt

Completed

Prospective Study of Short Course Radiation Therapy Followed by Neoadjuvant Chemotherapy and Surgery in Locally Advanced Rectal Cancer

Locally Advanced Rectal Carcinoma

Egypt
Fudan University

Unknown

A Study of Chinese Herbal Compound Dendrobium Huoshanense Granules in NCRT for Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Thomas Zilli
University Hospital, Geneva

Terminated

Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy

Rectal Cancer | Advanced Cancer | Rectal Tumors

Switzerland
RenJi Hospital

Active, not recruiting

Neoadjuvant Chemotherapy Combined With Cetuximab for EGFR Wild Type Locally Advanced Rectal Cancer

Rectal Cancer Stage III

China
Zhu Ji

Unknown

Tumor Response Prediction in Neoadjuvant Chemoradiation of Locally Advanced Rectal Cancer Using Metabonomics Analysis

Locally Advanced Rectal Cancer

China
Maastricht University Medical Center

Completed

Minimal Invasive Strategies for Good and Complete Response to Chemoradiation in Rectal Cancer

Locally Advanced Rectal Cancer

Netherlands
Zhejiang Cancer Hospital

Unknown

Nimotuzumab in Combination With Chemoradiation in Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Centre Hospitalier Universitaire de Besancon
Bayer

Completed

Regorafenib in Combination With Metronomic Chemotherapies, and Low-dose Aspirin in Metastatic Colorectal Cancer (REPROGRAM-01)

Metastatic Cancer | Colo-rectal Cancer

France
Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver

Neoplasm Metastasis | Colorectal Neoplasm | Liver Neoplasm

United States
Freenome Holdings Inc.

Completed

AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test

Adenoma | Polyps | Cancer, Rectum | Polyp of Colon | Colo-rectal Cancer | Adenoma Colon | Neoplasms,Colorectal | Cancer Colon

United States, Canada
Fudan University

Not yet recruiting

CAPOX and PD-1 Antibody Combined With or Without Radiotherapy for MSS Locally Advanced Rectal Cancer (TORCH-iTNT)

Neoadjuvant Therapy | Locally Advanced Rectal Cancer

China
Grupo Espanol Multidisciplinario del Cancer Digestivo

Recruiting

GEMCAD-REVEAL STUDY - Circulating Tumor DNA as a Predictor of Relapse in Patients With Locally Advanced Rectal Cancer. (REVEAL)

Patients With Locally Advanced Rectal Cancer

Spain
Fudan University

Active, not recruiting

Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer (REAL)

Rectal Carcinoma

China
King Faisal Specialist Hospital & Research Center

Completed

A Trial of Pre-Operative Chemoradiotherapy Using Capecitabine, Radiation & Cetuximab, in Rectal Cancer

Colon Rectal Cancer Duke Stage Stageval

Saudi Arabia
Austrian Breast & Colorectal Cancer Study Group

Terminated

Randomized Study on Neoadjuvant Radio-Chemotherapy in Rectal Carcinoma Dukes B and C

Rectal Cancer Dukes B, Dukes C

Austria
Jinhua Central Hospital

Not yet recruiting

Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer (CASINOs)

Locally Advanced Rectal Cancer

China
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Evaluation of the Efficacy and Safety of Interleucin-2 Combined With PD-1 Monoclonal Antibody and CAPOX in Preoperative Neoadjuvant Therapy for Locally Advanced Rectal Cancer - a Multicenter, Single-arm, Open-label Clinical Trail

Locally Advanced Rectal Adenocarcinoma
Vejle Hospital

Recruiting

MRI T1 Relaxation Time in Rectal Cancer

Rectal Cancer | Locally Advanced Rectal Carcinoma

Denmark
Beijing Friendship Hospital

Recruiting

Total Neoadjuvant Therapy Combined With Tislelizumab for Local Advanced of Middle and Low Rectal Cancer

Locally Advanced Rectal Cancer

China
Massachusetts General Hospital
C2i Genomics; Spier Family Foundation

Not yet recruiting

ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer

Rectal Cancer | Non Metastatic Rectal Cancer

United States

Clinical Trials on Rectal Neoplasms

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