Clinical Trials on Recurrent Brain Metastases

Total 39426 results

Nektar Therapeutics

Completed

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine (ATTAIN)

Breast Cancer | Metastasis

United States, Australia, Belgium, Canada, France, Israel, Italy, Portugal, Spain, United Kingdom
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bayer

Completed

Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors

Brain Metastases | Primary Brain Tumors

United States
National Cheng-Kung University Hospital

Recruiting

Surgical Resection Outcomes in Patients With Brain Metastasis

Brain Metastases

Taiwan
M.D. Anderson Cancer Center
Blue Earth Diagnostics

Not yet recruiting

A Pilot Study to Assess the Clinical Utility of 18F-Fluciclovine (Axumin) PET-CT for Detecting True-versus Pseudo-Progression of Brain Metastases on Immunotherapy

Brain Metastases

United States
M.D. Anderson Cancer Center

Recruiting

Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)

Brain Metastases

United States
Haaglanden Medical Centre

Recruiting

Improving Therapeutic Ratio With Hypo Fractionated Stereotactic Radiotherapy for Brain Metastases (SAFESTEREO)

Brain Metastases

Netherlands
Institut Català d'Oncologia

Recruiting

IORT After Surgical Resection of Brain Metastases (IORT_BRAINM1)

Brain Neoplasms

Spain
Massachusetts General Hospital

Recruiting

NTS-WBRT in Brain Metastases

Brain Metastases

United States
Xiangya Hospital of Central South University

Recruiting

Phase 1 Trial for Tumor Treating Field for Drug/Radiation Resistant Brain Metastases

Brain Metastases

China
Medical University of Vienna

Recruiting

Dose-staged Gamma Knife Radiosurgery Versus Microsurgical Resection

Brain Metastases

Austria
Assistance Publique - Hôpitaux de Paris

Recruiting

ASL in Brain Metastasis MRI Following Gamma Knife Treatment (GK-ASL)

Brain Metastases

France
Medical University Innsbruck

Recruiting

HA-WBRT vs SRS in Patients With Multiple Brain Metastases (HipSter)

Brain Metastases

Austria
Canadian Cancer Trials Group
Alliance for Clinical Trials in Oncology; NRG Oncology

Recruiting

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Brain Metastases

Canada, United States
Sunnybrook Health Sciences Centre

Recruiting

Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS)

Brain Metastases

Canada
Universitätsmedizin Mannheim

Recruiting

Intraoperative Radiotherapy After the Resection of Brain Metastases (INTRAMET)

Brain Metastases

Germany
University of Chicago

Recruiting

Frameless Stereotactic Radiosurgery for Intact Brain Metastases

Brain Metastases

United States
Indiana University

Active, not recruiting

Pre-operative Stereotactic Radiosurgery Followed by Resection for Patients With Brain Metastases

Brain Metastases

United States
University Hospital Heidelberg

Suspended

Supportive Care With or Without Repeated Whole Brain Radiotherapy in Patients With Recurrent Brain Metastases (RECARE)

Brain Metastases

Germany
Blue Earth Diagnostics
Precision For Medicine

Completed

Study to Establish Image Interpretation Criteria for 18F Fluciclovine PET in Detecting Recurrent Brain Metastases (PURSUE) (PURSUE)

Brain Metastases

United States
University of Arkansas

Terminated

Preoperative SRS/SRT vs Postoperative SRS/SRT for Brain Metastases

Brain Metastases

United States
Sun Yat-sen University
Cancer Hospital of Guangxi Medical University; First Affiliated Hospital of... and other collaborators

Enrolling by invitation

Treatments for Brain Metastases With Poor Prognostic Factors (TBMPPF)

Brain Metastases

China
EpicentRx, Inc.

Completed

Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases (BRAINSTORM)

Brain Metastases

United States
University Health Network, Toronto
Princess Margaret Hospital, Canada

Completed

Dexamethasone for Palliation - Brain Metastases

Neoplasm Metastasis

Canada
Amsterdam UMC, location VUmc
UMC Utrecht; The Netherlands Cancer Institute

Terminated

Local Radiotherapy Following Complete Resection of a Brain Metastasis

Brain Neoplasms

Netherlands
Guangdong Association of Clinical Trials

Unknown

The Impact of Neurocognitive Function in Patients With Multiple Brain Metastases Receiving Whole Brain Radiation Therapy

Brain Metastases

China
University of Alabama at Birmingham

Completed

Dose Escalation/De-escalation Study of Pre-operative Stereotactic Radiosurgery for Brain Metastases(RAD 1002) (RAD 1002)

Brain Metastases

United States
University of California, San Francisco
North American Gamma Knife Consortium

Terminated

A Single Arm Study of Neurocognitive Outcomes in Patients With Brain Metastases Managed With Stereotactic Radiosurgery (SRS)

Brain Metastases

United States
Bayer

Completed

SH L 562BB Phase II/III Dose Justification and Gadoteridol-controlled Comparative Study

Brain Metastases

Japan
Washington University School of Medicine

Completed

Response of Brain Metastases After Gamma-Knife Radiosurgery Using Dynamic Susceptibility-weighted Contrast-enhanced Perfusion Magnetic Resonance Imaging

Brain Metastases

United States
H. Lee Moffitt Cancer Center and Research Institute
Schering-Plough

Terminated

Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases

Brain Metastases

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases

Neoplasm Metastasis

United States
Alberta Health services
Tom Baker Cancer Centre

Unknown

Frameless Stereotactic Radiosurgery for Brain Metastases

Brain Metastases

Canada
University Hospital, Essen

Unknown

Whole-Brain Radiotherapy (WBRT) Versus WBRT and Integrated Boost Using Helical Tomotherapy for Multiple Brain Metastases

Brain Metastases

Germany
Tel-Aviv Sourasky Medical Center

Unknown

Stereotactic Radiosurgery to the Resection Cavity Following Surgical Removal of Brain Metastasis

Brain Neoplasms

Israel
University Hospital Heidelberg

Recruiting

Neoadjuvant vs. Intraoperative vs. Adjuvant Resection Cavity Radiotherapy of Brain Metastases (Radcav)

Brain Metastases | Radiotherapy

Germany
M.D. Anderson Cancer Center
Eisai Inc.

Recruiting

Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases

Tumor | Brain Metastases

United States
University Health Network, Toronto

Recruiting

FLT-PET / MRI Brain Mets

Brain Metastases | Radionecrosis

Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Genentech, Inc.

Terminated

Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases

Brain Metastases | Radionecrosis

United States, Canada
Henan Cancer Hospital

Recruiting

A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)

NSCLC | Brain Metastases | Leptomeningeal Metastasis

China
Eastern Hepatobiliary Surgery Hospital

Not yet recruiting

Neoadjuvant Therapy for Resectable Intrahepatic Cholangiocarcinoma With High Predict Risk of Lymph Node Metastasis

Intrahepatic Cholangiocarcinoma Recurrent
Centre Oscar Lambret
Centre Hospitalier Universitaire de Besancon

Terminated

Prospective Assessment of Quality of Life in Patients Treated by Radiosurgery for Brain Metastases (PRAMECE-1302) (PRAMECE-1302)

Neoplasm Metastases

France
Fudan University

Not yet recruiting

SHR-A1921 Combined With Bevacizumab in Triple-negative Breast Cancer With Brain Metastases

Brain Metastasis | TNBC

China
Cancer Institute and Hospital, Chinese Academy...

Completed

Sequence of Radiation and Targeted Therapy in Brain Metastases

The Optimal Sequence of Radiotherapy and Systematic Tyrosine Kinase Inhibitors in Treating Brain Metastases

China
Ottawa Hospital Research Institute

Not yet recruiting

Hippocampal-Sparing Stereotactic Radiosurgery Treatment of Brain Metastases Using CyberKnife (HiSparCK)

Brain Metastases | Radiosurgery
University of Alabama at Birmingham
Integrated Therapeutics Group

Completed

Phase II Study of Gamma Knife Radiosurgery and Temozolomide for Brain Metastases (RAD0102)

Cancer | Brain Metastases

United States
Amsterdam UMC, location VUmc

Recruiting

COLLISION RELAPSE Trial

Recurrence | Colorectal Cancer | Surgery | Chemotherapy Effect | Liver Metastases | Liver Metastasis Colon Cancer

Netherlands
Fuda Cancer Hospital, Guangzhou

Completed

Irreversible Electroporation(IRE) For Unresectable Lymph Node Metastases(Close to Nerve) (IRE)

Lymph Node Metastases

China
Convalife (Shanghai) Co., Ltd.

Not yet recruiting

Nilatinib Maleate Tablets Combined With Capecitabine in the Treatment of HER2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastases

Her2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastasis
University of Alabama at Birmingham

Not yet recruiting

MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors

Healthy Volunteers | Recurrent Glioma | Brain Metastases From Extra-cranial Solid Tumors

United States
The Cooper Health System

Withdrawn

Stereotactic Radiosurgery (SRS) for Multiple CNS Mets

Metastatic Cancer | Brain Metastases

United States

Clinical Trials on Recurrent Brain Metastases

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