Clinical Trials on Recurrent High Risk Myelodysplastic Syndrome

Total 3268 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Untreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | High Risk Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome | Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1 | Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 | Acute Myeloid... and other conditions

United States
Array BioPharma

Completed

A Phase Ib Study of MEK162 Plus BYL719 in Adult Patients With Selected Advanced Solid Tumors

AML | Advanced and Selected Solid Tumors | High Risk and Very High Risk MDS

United States, Australia, Italy, Spain, France, Switzerland, United Kingdom
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Bellicum Pharmaceuticals

Withdrawn

Rivogenlecleucel Donor Lymphocyte Immunotherapy in Treating Patients With Recurrent Blood Cancers After Stem Cell Transplant

Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic Syndrome | Recurrent Acute Lymphoblastic Leukemia | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm | Myelodysplastic... and other conditions

United States
Southeast University, China

Recruiting

Machine Learning-based Early Clinical Warning of High-risk Patients

High-risk Patients | Risk Reduction | Machine Learning

China
University of Washington
National Cancer Institute (NCI)

Completed

Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms

Previously Treated Myelodysplastic Syndrome | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts-2 | Myeloid Neoplasm | Chronic Myelomonocytic Leukemia-2 | Blasts 10 Percent or More of Bone Marrow Nucleated... and other conditions

United States
Massachusetts General Hospital
National Cancer Institute (NCI); Dana-Farber Cancer Institute; Damon Runyon Cancer...

Completed

Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract

Colorectal Polyps | High Risk Polyposis Syndrome | Distal Colonic Lesions

United States
George Washington University
University of North Carolina, Chapel Hill; Aga Khan University; Kenya Medical... and other collaborators

Recruiting

PRISMA Maternal and Newborn Health Study (PRiSMA-MNH)

Pregnancy, High Risk

Pakistan, Ghana, Kenya, India, Zambia
George Washington University

Active, not recruiting

Validation of a Non-invasive Hemoglobin Measurement Device in Pregnancy and Postpartum in Kenya, Pakistan, and Zambia

Pregnancy, High Risk

Pakistan, Zambia, Kenya
London School of Hygiene and Tropical Medicine
Rawalpindi Medical College

Completed

Pharmacokinetics and Pharmacodynamics of Tranexamic Acid in Women Having Caesarean Section Birth [WOMAN-PharmacoTXA]

Pregnancy, High Risk

Pakistan, Zambia
University of Aarhus
Copenhagen University Hospital, Hvidovre

Completed

An Adapted Mindfulness-based Stress Reduction Program for Psycho-socially Vulnerable Pregnant Women.

Pregnancy, High Risk

Denmark
Ain Shams University

Completed

Frequency of Performing Umbilical Artery Doppler in the Third Trimester in High Risk Pregnancy

High Risk Pregnancy

Egypt
Northwestern University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Completed

Testing a Medication Risk Communication and Surveillance Strategy: The EMC2 Trial

High-risk Medications

United States
University Hospital, Lille

Completed

Perception of Risks Into Work During Pregnancy Among Post-partum Women in the Lille Metropolis (PERISTRAG)

Pregnancy, High Risk

France
University of British Columbia
National Institutes of Health (NIH)

Completed

Campus Health Intervention Projects UBC Site

High Risk Drinking

Canada
Istituto Giannina Gaslini

Recruiting

Music Therapy and High-risk Pregnancy

High Risk Pregnancy

Italy
Fondazione GISE Onlus
University of Padova; Abiomed Inc.

Recruiting

The PROTECT-EU Study

High-risk PCI

Italy
Lo.Li.Pharma s.r.l

Completed

Use of Dietary Supplements in Patients at Risk of Abortion Treated With Progesterone.

Pregnancy, High Risk

Italy
Indiana University

Completed

Coconut Oil vs. Commercial Ultrasound Gel In Obstetric Ultrasounds

Pregnancy, High Risk

United States
Oregon Health and Science University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Placenta Imaging Project (PIP)

High Risk Pregnancy

United States
University of Texas Southwestern Medical Center

Completed

Adjunctive Smart Phone Based Smoking Cessation Treatment

High-Risk Cancer
Mount Sinai Hospital, Canada
Ontario Mental Health Foundation

Unknown

Does Mid-Gestation Placental Function Assessment Reduce Psychological Distress in Women With High-Risk Pregnancies?

High-Risk Pregnancy

Canada
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); Karyopharm Therapeutics Inc

Not yet recruiting

Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Relapsed Myelodysplastic Syndrome

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

Recurrent Adult Acute Myeloid Leukemia | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult... and other conditions

United States, Germany
Nursel Alp Dal

Completed

Guided Imagery on the Perceived Stress Level in High-Risk Pregnancies

High Risk Pregnancy

Turkey
Cairo University

Completed

Effects of Fetal Movement Counting on Maternal and Fetal Outcome Among High Risk Pregnant Woman

Pregnancy | High Risk

Egypt
University of Utah

Completed

Use Of An In-Home Non-Stress Test Device For Remote Fetal Monitoring

High Risk Pregnancy

United States
The First Affiliated Hospital of Soochow University

Unknown

Decitabine for Myelodysplastic Syndromes and Acute Myeloid Leukemia Before Allogeneic Hematopoietic Cell Transplantation (DFMBHSCT)

Higher-risk Myelodysplastic Syndrome | Relapsed /Refractory Acute Myeloid Leukemia
University of Southern California
National Cancer Institute (NCI); Van Andel Research Institute

Active, not recruiting

Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

Chronic Myelomonocytic Leukemia | Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes | Myelodysplastic Syndrome

United States
GT Biopharma, Inc.

Terminated

GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies

Acute Myelogenous Leukemia | Systemic Mastocytosis | Mast Cell Leukemia | High-risk Myelodysplastic Syndromes

United States
Beijing Anzhen Hospital

Recruiting

Standby Cannulated ECMO for High-Risk Percutaneous Coronary Intervention (ESCORT)

High-risk PCI | ECMO

China
Yalda Afshar, MD, PhD
University of California, Los Angeles

Recruiting

UCLA Perinatal Biospecimen Repository

Pregnancy | High-Risk Pregnancy

United States
VIVE - The Danish Center for Social Science Research
Yale University; Metodecentret - Center for Effective Innovation in Social...

Recruiting

The Effectiveness of MInding the Baby in a Danish Community Sample (MTB)

Pregnancy, High Risk | Family

Denmark
Motao Zhu
Centers for Disease Control and Prevention

Active, not recruiting

Behind the Wheel (BTW) Smartphone Application (BTW)

High-risk Driving Events

United States
The University of Texas Health Science Center,...
Merck Sharp & Dohme LLC

Active, not recruiting

Use of an Educational Multimedia Tool Versus Routine Care for the Uptake of Postpartum LARC in High-Risk Pregnancies (SUSTAIN)

Pregnancy, High Risk | Contraception

United States
Università Politecnica delle Marche

Completed

A Therapy to Reduce Morbidity and Hospital Length of Stay of High-Risk Surgical Patients

High-Risk Surgical Patients

Italy
Prisma Health-Upstate

Recruiting

Prevent Cancer- Greenville (CCPW)

Cancer | High-Risk Cancer

United States
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Stress Test on the Prediction of Cardiovascular Events in a High-risk Firefighter Population (FIRE-PREV)

Firefighter | High Cardiovascular Risk

France
Medical University of Vienna

Unknown

DVA Risk Pregnancy

Pregnancy | High Risk Pregnancies

Austria
University of Ulm

Recruiting

Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms, and Higher Risk Myelodysplastic Syndrome - The Biology and Outcome (BiO)-Project (AMLSG BiO)

Acute Myeloid Leukemia (AML) | Higher Risk Myelodysplastic Syndromes (MDS With Excess Blasts 2)

Austria, Germany
Amgen

Completed

AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia

Chronic Myelomonocytic Leukemia | Higher Risk Myelodysplastic Syndrome

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Terminated

Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Celgene Corporation

Completed

Azacitidine in Treating Patients With Relapsed Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Suspended

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | Recurrent Acute Lymphoblastic... and other conditions

United States
National Cancer Institute (NCI)

Completed

Belinostat in Treating Patients With Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndromes | Secondary Myelodysplastic Syndromes | de Novo Myelodysplastic Syndromes

United States
Suez Canal University

Completed

Clinical Evaluation of Chemically Cured Conventional Glass Ionomer After Light Emitting Diode Radiant Heat Enhancement

High Caries Risk Patients

Egypt
Tammy Moore

Active, not recruiting

Testing the Effectiveness of a Falls Prevention System

High Risk for Falling

United States
Cairo University

Unknown

Assessment of Inhibition of Biofilm Formation and Plaque Bacterial Count of Fluoride Varnish Containing Chlorhexidine and Cetylpyridinium Chloride Versus Conventional Fluoride Varnish

High Caries Risk Patients

Egypt
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Measurement of Cardiac Index Using an Implanted Central Venous Access Port in Patients Scheduled for Oncologic High-risk Surgery (ThermoD-PAC)

Oncologic High-risk Surgery

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Azacitidine and Etanercept in Treating Patients With Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndromes | Secondary Myelodysplastic Syndromes | de Novo Myelodysplastic Syndromes

United States
University Health Network, Toronto

Active, not recruiting

Integrative Sequencing In Germline and Hereditary Tumours (INSIGHT)

Mutation | Hereditary Cancer Syndrome | High-Risk | Germline Mutation

Canada

Clinical Trials on Recurrent High Risk Myelodysplastic Syndrome

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