Clinical Trials on Reduced Corneal Sensation in South Africa

Total 629 results

Crowd Health Research, LTD

Unknown

Corneal Cross-Linking Comparing Variables

Unstable Corneas

United States
Fertin Pharma A/S

Completed

Single-Dose Bioequivalence Study Comparing Two 4 mg Nicotine Lozenges

Smoking Cessation

South Africa
Fertin Pharma A/S

Completed

Single-Dose Bioequivalence Study Comparing Two 2 mg Nicotine Lozenges

Smoking Cessation

South Africa
hearX Group
University of Pretoria

Completed

Clinical Validation of the Lexie Lumen Hearing Aid

Hearing Loss

South Africa
Johns Hopkins University
National Institute on Drug Abuse (NIDA); University of Witwatersrand, South... and other collaborators

Completed

A Smoking Cessation Trial in HIV-infected Patients in South Africa (JHU)

Smoking Cessation | HIV

South Africa
hearX Group

Completed

Comparing Self-Fitting Strategies in the Lexie Powered by Bose Hearing Aids

Hearing Loss

South Africa
Johns Hopkins University
National Cancer Institute (NCI); New York University; Colorado State University; Perinatal HIV Research Unit of the University of the Witswatersrand

Recruiting

Evaluating Smoking Cessation Interventions for PWH in South Africa (Tlogela)

Smoking Cessation | HIV | Comorbidities and Coexisting Conditions

South Africa
University of Stellenbosch
National Research Foundation of South Africa

Completed

Joint Position Sense in Individuals With Anterior Knee Pain

Proprioceptive Disorders | Anterior Knee Pain Syndrome

South Africa
Edward J. Holland
Alcon Research; Sirion Therapeutics, Inc.; Parsons Medical Communications

Completed

Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.

Corneal Edema | Cataracts | Visual Acuity Reduced Transiently | Retinal Structural Change, Deposit and Degeneration

United States
Massachusetts General Hospital
Boston University; University of Cape Town

Recruiting

South Africa Smoking Cessation and Engagement in HIV/TB Care Care

HIV Infections | Smoking Cessation | Tuberculosis

South Africa
University of Cape Town

Completed

The Role of Melatonin in the Effective Attainment of Sleep Electroencephalograms (EEG) in Children

Epilepsy | Children | Sedation | Electroencephalogram

South Africa
University of Witwatersrand, South Africa

Completed

Epidemiology of Congenital Cytomegalovirus in a High HIV Prevalence Setting, South Africa

Neurodevelopmental Disorders | Hearing Loss | Immunogenicity | Stillbirth | Neonatal Death | Cytomegalovirus Congenital

South Africa
University of Cape Town
Medical Research Council, South Africa

Completed

A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis (NAC in TB DIH)

Drug-Induced Liver Injury

South Africa
Ibis Reproductive Health
Society of Family Planning; University of Cape Town; Tygerberg Hospital; Safe Abortion...

Completed

Cervical Priming Before Dilation & Evacuation

Abortion, Induced

South Africa
University of Johannesburg
Medical Research Council, South Africa

Enrolling by invitation

Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump

Lead Poisoning | Lead Poison Children

South Africa
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Stellenbosch and other collaborators

Completed

The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology

Fetal Alcohol Spectrum Disorders

South Africa
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Human Sciences... and other collaborators

Active, not recruiting

Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa

HIV/AIDS | Alcohol Abuse

South Africa
University of California, Los Angeles

Active, not recruiting

Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)

Nutrition Disorders | HIV | Fetal Alcohol Syndrome

South Africa
Penn State University
National Institute on Drug Abuse (NIDA)

Completed

Adolescent Drug and HIV Prevention in South Africa

Substance-Related Disorders | Sexually Transmitted Diseases

South Africa
Bukwang Pharmaceutical
Contera Pharma ApS

Completed

Efficacy and Safety of JM-010 in PD With Levodopa-Induced Dyskinesia (LID)

Parkinson's Disease | Levodopa Induced Dyskinesia (LID)

South Africa
RTI International
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Medical Research...

Completed

Venue-Based Couples CoOp in South Africa (Couples CoOp)

HIV Infections | Alcoholism

South Africa
Ipas

Terminated

Developing and Testing Interventions to Address Conscientious Objection to Abortion Care in Mexico and South Africa

Abortion, Induced | Abortion, Incomplete

Mexico, South Africa
Wayne State University
Columbia University; University of Cape Town

Recruiting

RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome

South Africa
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Completed

HIV & Drug Abuse Prevention for South African Men

Substance-Related Disorders | Alcoholism | Human Immunodeficiency Virus

South Africa
Eunice Kennedy Shriver National Institute of Child...
Medical Research Council, South Africa

Completed

Women-Focused HIV Prevention in the Western Cape (WC-WHC)

HIV | Substance Abuse | Violence

South Africa
RTI International
University of Cape Town

Completed

Treating South African Pregnant Women for Methamphetamine

HIV | Drug Addiction

South Africa
Aerie Pharmaceuticals

Completed

A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy (Fuchs)

Corneal Edema

United States
RTI International
Medical Research Council, South Africa

Recruiting

Couples Health CoOp Plus (CHC+)

HIV | Substance Use | Stigma, Social

South Africa
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Eclampsia

Eclampsia

South Africa
University of Cape Town
Medical University of Vienna; University of Washington

Completed

Acid-Base and Point of Care Ultrasound in Severe Preeclampsia

Pre-Eclampsia

South Africa
University of Stellenbosch
Stanley Medical Research Institute

Completed

Ethyl-Eicosapentaenoic Acid and Tardive Dyskinesia

Schizophrenia | Dyskinesia

South Africa
Southern Illinois University

Terminated

Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL)

Noise-induced Hearing Loss

United States
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia

Preeclampsia | Pulmonary Edema | Cardiac Function

South Africa
Kowa Research Institute, Inc.

Completed

Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis

Fuchs' Endothelial Corneal Dystrophy

United States, Australia, Germany, Spain, Denmark
Trefoil Therapeutics, Inc.

Completed

A Phase 1/ Phase 2 Study of TTHX1114(NM141) (INTREPID)

Endothelial Dysfunction | Corneal Endothelial Dystrophy | Pseudophakic Bullous Keratopathy | Fuchs Endothelial Corneal Dystrophy

United States
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Alcohol-Related Disorders | Substance Use | Drug Use | Human Immunodeficiency Virus

South Africa
University of California, Los Angeles
University of Stellenbosch; The ELMA Foundation; Philani Maternal Child Health...

Completed

Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa

Depression | HIV Infections | Alcohol Drinking | Alcohol; Harmful Use | HIV/AIDS | Depressive Symptoms | Child Development | Alcohol Use Disorder | Stunting | Child Nutrition Disorders | Child Malnutrition | Birth Weight Less Than 10Th Percentile

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
University of Stellenbosch
QuitSupport

Completed

Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation

Tobacco Dependence

South Africa
Johnson & Johnson Surgical Vision, Inc.

Completed

Clinical Investigation of Two Tecnis Investigational Lenses

Cataract | Corneal Astigmatism

Australia, New Zealand
Aurion Biotech

Recruiting

A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1) (CLARA)

Corneal Edema | Corneal Endothelial Dysfunction

United States, Canada
Medical University of South Carolina

Recruiting

Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder

Smoking Cessation | Tobacco Use | Nicotine Dependence

United States
University of Washington
University of Cape Town

Completed

Evaluation of Metabolic Acid-base Abnormalities in Pre-eclamptic Women Applying the Stewart-Fencl Approach

Severe Pre-eclampsia | Mild Pre-eclampsia

South Africa, United States
Glaukos Corporation

Completed

Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus

Keratoconus

United States
RTI International
Kheth'Impilo

Completed

Implementation Research for Vulnerable Women in South Africa

HIV | Substance Abuse

United States, South Africa
Medical University of South Carolina

Completed

Enhancing Self Regulation Among Smokers (MIMIC)

Smoking Cessation | Nicotine Dependence | Smoking, Cigarette

United States
RTI International
University of North Carolina, Chapel Hill

Completed

WHC+ (Women's Health CoOp PLUS)

Sexually Transmitted Diseases | HIV | Substance Abuse | Violence | Victimization | Sexual Risk

United States, South Africa
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Alcoholism | Hepatic Cirrhosis

Germany, Belgium, United States, South Africa
Alcon Research

Completed

Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Toric IOL in an Asian Population

Corneal Astigmatism | Aphakia

Australia

Clinical Trials on Reduced Corneal Sensation in South Africa

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