Clinical Trials on Refractory Osteosarcoma

Total 3206 results

Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Polatuzumab Vedotin, Venetoclax, and Rituximab and Hyaluronidase Human for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Grade 3a Follicular... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Peripheral Blood Stem Cell Transplant and Pretargeted Radioimmunotherapy in Treating Patients With High-Risk Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable | Refractory Anemia With Excess... and other conditions

United States
Astex Pharmaceuticals, Inc.

Withdrawn

Study of SGI-1776, a PIM Kinase Inhibitor, in Subjects With Relapsed/Refractory Leukemias

Relapsed/Refractory Leukemias

United States
PharmaMar

Terminated

Clinical Study of Plitidepsin (Aplidin®) in Combination With Cytarabine in Patients With Relapsed/Refractory Leukemia

Relapsed/Refractory Leukemia

United States
The Affiliated Hospital of the Chinese Academy...
Chinese PLA General Hospital

Unknown

Allogeneic CART-33 for Relapsed/Refractory CD33+ AML

Relapsed and/or Refractory CD33+ AML

China
University of California, Irvine
Beckman Laser Institute University of California Irvine

Completed

Monitoring Chemotherapy Response of Soft Tissue Sarcomas and Osteosarcomas Using Diffuse Optical Spectroscopic Imaging

Sarcoma

United States
NKGen Biotech, Inc.

Active, not recruiting

Study of Allogeneic Blood-derived Natural Killer Cells to Evaluate Safety and Tolerability in Cancer Refractory to Conventional Therapy

Solid Tumor | Metastatic Cancer | Advanced Solid Tumor | Advanced Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer | Pathologically Confirmed Cancer Refractory to Conventional Therapy

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

TTI-622 and TTI-621 in Combination With Pembrolizumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent Diffuse Large B-Cell... and other conditions

United States
University of Minnesota

Recruiting

Biology of Osteosarcoma (BOOST) Registry and Biobank (BOOST)

Osteosarcoma

United States
CytoMed Therapeutics Pte Ltd
National University Hospital, Singapore

Not yet recruiting

Allogeneic NKG2DL-targeting CAR γδ T Cells (CTM-N2D) in Advanced Cancers (ANGELICA)

Cancer | Malignancy | Relapsed Cancer | Refractory Cancer

Singapore
National Cancer Institute (NCI)

Active, not recruiting

Trametinib and Navitoclax in Treating Patients With Advanced or Metastatic Solid Tumors

Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Abramson Cancer Center of the University of Pennsylvania

Withdrawn

Palliative Care Outcomes in the Management of Malignant Ascites by Interventional Radiology

Refractory Malignant Ascites

United States
Weill Medical College of Cornell University

Terminated

Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT)

Glucocorticosteroid Refractory Acute GVHD

United States
University of Leipzig

Completed

Renal Sympathetic Denervation in Mild Refractory Hypertension

Refractory Hypertension

Germany
Istituto Ortopedico Rizzoli

Recruiting

Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma

Ewing Sarcoma

Italy
St. Jude Children's Research Hospital
Pfizer; Gateway for Cancer Research

Completed

A Phase II Trial of Avelumab in Patients With Recurrent or Progressive Osteosarcoma

Osteosarcoma

United States
Universität Duisburg-Essen
Ruhr University of Bochum

Completed

Exercise Intervention for Bone Tumor Patients (proGAIT)

Bone Sarcoma

Germany
Institut Curie

Completed

Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives (GENEWING)

Sarcoma

France
Sarcoma Alliance for Research through Collaboration
AstraZeneca

Terminated

A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the Lung

Osteosarcoma

United States
University of Oxford
National Institute for Health Research, United Kingdom; European Commission; Oxford... and other collaborators

Terminated

A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma (MEMOS) (MEMOS)

Osteosarcoma

United Kingdom, Germany, Italy, Netherlands, Norway
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker in Tissue Samples From Patients With Ewing Sarcoma

Sarcoma
University of Michigan Rogel Cancer Center

Completed

A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma (OCR)

Osteosarcoma

United States
University Hospital Muenster
Medical Research Council

Unknown

Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma

Sarcoma

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Withdrawn

Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly Diagnosed Localized Ewing's Sarcoma

Sarcoma
Children's Cancer and Leukaemia Group

Completed

Irinotecan in Treating Patients With Newly Diagnosed Ewing's Sarcoma

Sarcoma

United Kingdom, Ireland
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Ecteinascidin 743 in Treating Patients With Previously Treated Metastatic Osteosarcoma

Sarcoma

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma

Sarcoma

United States
The First Affiliated Hospital of Soochow University

Not yet recruiting

Selinexor and HAAG With/Without HMA in Relapsed/Refractory Acute Leukemia (AML) Patients

Relapsed/Refractory AML

China
Assiut University

Not yet recruiting

Comparison Between Two Techniques of Subthreshold Diode Laser Cyclophotocoagulation in Refractory Glaucoma

Refractory Glaucoma
Fudan University

Recruiting

Intraperitoneal Injection of Oncolytic Viruses H101 for Patients With Refractory Malignant Ascites

Refractory Malignant Ascites

China
Allergan

Completed

Real-world Evidence Study of XEN in Chinese Patients With Refractory Glaucoma

Refractory Glaucoma

China
M.D. Anderson Cancer Center

Active, not recruiting

Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Hadassah Medical Organization

Unknown

Allo-Allo Tandem Bone Marrow Transplant (BMT) (AATT)

Refractory Acute Leukemia

Israel
Vanak Eye Surgery Center

Unknown

Ahmed Valve Glaucoma Implant With Adjunctive Subconjunctival Bevacizumab in Refractory Glaucoma

Refractory Glaucoma

Iran, Islamic Republic of
Vanak Eye Surgery Center

Completed

Ahmed Glaucoma Valve and Single-Plate Molteno Implants in Treatment of Refractory Glaucoma

Refractory Glaucoma

Iran, Islamic Republic of
Shahid Beheshti University of Medical Sciences

Unknown

Ahmed Glaucoma Valve Alone, With Amniotic Membrane or With Mitomycin C (MMC) for Treatment of Refractory Glaucoma

Refractory Glaucoma

Iran, Islamic Republic of
Children's Hospital of Philadelphia
Children's Hospital Colorado; Exelixis; Alex's Lemonade Stand Foundation

Recruiting

Cabozantinib With Ifosfamide in Ewing's Sarcoma and Osteosarcoma

Osteosarcoma | Ewing Sarcoma

United States
MedPacto, Inc.

Recruiting

Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

Osteosarcoma

United States, Korea, Republic of
Istituto Ortopedico Rizzoli
International Agency for Research on Cancer

Recruiting

Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma (Metabol-Sarc)

Osteosarcoma | Ewing Sarcoma

Italy
Krishnadevaraya College of Dental Sciences & Hospital

Completed

Extracorporeal Shock Wave Therapy on Osteoblast-Like Cells In- Vitro Study (ESWT)

Osteosarcoma

India
Sarcoma Alliance for Research through Collaboration

Completed

ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing Sarcoma

Ewing Sarcoma

United States, United Kingdom
Jonsson Comprehensive Cancer Center
NantCell, Inc.

No longer available

Single Patient Expanded Access to Ganitumab for Metastatic Ewing Sarcoma

Ewing Sarcoma
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of Tumors

Sarcoma

United States, Canada, Puerto Rico, Australia
Byung-Kiu Park
Samsung Medical Center; Chungnam National University Hospital

Unknown

Feasibility Study of Interval Compressed Regimen Using Four-drugs for Osteosarcoma

Feasibility | Osteosarcoma | Biomarker | Treatment Response

Korea, Republic of
University of Louisville

Withdrawn

A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma (ASCT)

Ewing Sarcoma

United States
National Cancer Center, Korea

Completed

Development of Indices Predicting Response to Pre-operative Chemotherapy in Osteosarcoma Patients

Osteosarcoma

Korea, Republic of
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Tissue Samples From Patients With Ewing Sarcoma

Sarcoma
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's Sarcoma

Sarcoma

United States
Epeius Biotechnologies

Completed

Phase II Study of Intravenous Rexin-G in Osteosarcoma

Osteosarcoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States

Clinical Trials on Refractory Osteosarcoma

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CROs in Mongolia

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