Clinical Trials on Refractory Arterial Hypertension in Japan

Total 651 results

Viatris Pharmaceuticals Japan Inc

Completed

Revatio Special Investigation for Long-term Use in Pediatric Patients

Pulmonary Arterial Hypertension

Japan
Kyorin University

Completed

Submacular Hemorrhage Associated With Retinal Arterial Macro Aneurysm

Submacular Hemorrhage | Ruptured Retinal Arterial Macro Aneurysms

Japan
Novartis Pharmaceuticals

Completed

Open-label, Multi-center Protocol to Provide QTI571 to PAH Patients Who Participated in the Extension Study (A2301E1) in Japan

Severe Pulmonary Arterial Hypertension

Japan
Bayer

Completed

Non-interventional, Postauthorization Safety Study of Ventavis for Pulmonary Arterial Hypertension (PAH)

Hypertension, Pulmonary

Japan
Bayer

Completed

Prospective, Non-interventional, Multi-center, Post-authorization Safety Study of Riociguat for Pulmonary Arterial Hypertension (PAH) (JPMS-PAH)

Hypertension, Pulmonary

Japan
GlaxoSmithKline

Completed

Evaluation of a New Thermostable Formulation of FLOLAN in Japanese Subjects

Cardiovascular Disease

Japan
Pfizer

Terminated

Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients

Hypertension, Pulmonary

Japan
Pfizer

Terminated

A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients

Hypertension, Pulmonary

Japan
International University of Health and Welfare
Japan Agency for Medical Research and Development; Chugai Pharmaceutical; Keio...

Recruiting

Satralizumab in the Treatment of Pulmonary Arterial Hypertension (SATISFY-JP Trial)

Pulmonary Arterial Hypertension

Japan
Idorsia Pharmaceuticals Ltd.

Terminated

Tezosentan in Patients With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, Japan, France
GlaxoSmithKline

Completed

A Study to Evaluate GSK1325760A - a Long-Term Extension Study

Pulmonary Arterial Hypertension | Hypertension, Pulmonary

Japan
Acrobat Trial Group

Unknown

ARB and CCB Longest Combination Treatment on Ambulatory and Home BP in Hypertension With Atrial Fibrillation -Multicenter Study on Time of Dosing (ACROBAT) (ACROBAT)

Hypertension and Atrial Fibrillation

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension | Hypertension, Pulmonary

Japan
Bayer

Completed

A Study to Understand the Treatment Patterns in Patients With Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension During a Switch of Treatment to Adempas in Real-life Clinical Practice (CAPTURE)

Hypertension, Pulmonary

Japan, Germany, Sweden, Colombia, Turkey, Belgium, Canada
GlaxoSmithKline

Completed

Evaluate the Efficacy, Safety and Pharmacokinetics of GSK1325760A in the Treatment of Pulmonary Arterial Hypertension

Hypertension, Pulmonary

Japan
Kumamoto University
Japan Heart Foundation; The 4C trial bureau

Completed

Candesartan for Prevention of Cardiovascular Events After Cypher or Taxus Coronary Stenting (4C) Trial

Coronary Artery Disease | Hypertension

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Open Label Study of Sildenafil in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

Japan
Takeshi Morimoto

Terminated

Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound (PREVUS)

Coronary Artery Disease | Hypertension

Japan
Juntendo University
Japan Heart Foundation

Completed

Azelnidipine Anti-Coronary Atherosclerotic Trial in Hypertensive Patients by Serial Volumetric IVUS Analysis(ALPS-J)

Hypertension | Coronary Atherosclerosis

Japan
C. R. Bard
Medicon, Inc.

Completed

LEVANT Japan Clinical Trial

Femoral Artery Occlusion | Femoral Arterial Stenosis | Stenosis of Popliteal Arteries | Occlusion of Popliteal Arteries

Japan
Janssen Pharmaceutical K.K.

Recruiting

A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Long Term Extension Study Evaluating Safety Of Sildenafil Citrate When Used To Treat Pulmonary Arterial Hypertension (PAH) In Children

Pulmonary Arterial Hypertension

United States, Colombia, Russian Federation, Taiwan, Guatemala, India, Mexico, Japan, Italy, Brazil, Hungary, Poland, Malaysia, Sweden, Chile
Daiichi Sankyo Co., Ltd.

Completed

Phase 1 Study of Quizartinib

Relapsed AML | Refractory AML

Japan
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Sotatercept in Japanese Pulmonary Arterial Hypertension (PAH) Participants (MK-7962-020)

Pulmonary Arterial Hypertension

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children With Pulmonary Arterial Hypertension.

Pulmonary Arterial Hypertension, Children

United States, Taiwan, Guatemala, Russian Federation, Japan, Chile, Colombia, Canada, Italy, Hungary, Poland, Peru, Sweden, Brazil, India, Malaysia, Mexico
Actelion

Terminated

A Study of Real-world Cohort of Pulmonary Arterial Hypertension (PAH) Participants (CARE PAH)

Pulmonary Arterial Hypertension

United States, Germany, Korea, Republic of, United Kingdom, China, Canada, Netherlands, Italy, Japan, Poland, Spain, Brazil, Malaysia, Argentina, Singapore, Puerto Rico, Sweden
Jikei University School of Medicine

Unknown

A Morbidity-Mortality and Remodeling Study With Valsartan

Hypertension | Ischemic Heart Disease | Congestive Heart Failure

Japan
Novartis

Completed

Study Comparing SPP100 (Aliskiren) 150mg to Placebo and to Losartan 50mg in Patients With Mild to Moderate Essential Hypertension

Hypertension

Japan
Kyoto Prefectural University of Medicine

Completed

Add-on Effects of Valsartan on Morbi- Mortality (KYOTO HEART Study)

Stroke | Hypertension | Ischemic Heart Disease | Congestive Heart Failure

Japan
Bayer

Completed

Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy (REPLACE)

Pulmonary Arterial Hypertension

Belgium, France, Spain, Portugal, Turkey, United States, Germany, Korea, Republic of, Mexico, Austria, Canada, Denmark, Poland, Italy, Greece, Taiwan, Czechia, Netherlands, Japan, Brazil, United Kingdom
Novartis

Completed

Pharmacokinetic and Pharmacodynamic Profiles of Aliskiren in Japanese Patients With Mild to Moderate Essential Hypertension

Hypertension

Japan
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Valsartan and Amlodipine in Patients With Essential Hypertension

Essential Hypertension

Japan
Kyoto University

Completed

Efficacy and Safety of Weak Extremely Low Frequency Electromagnetic Fields in Mild and Moderate Essential Hypertension

Essential Hypertension

Japan
Bayer
Merck Sharp & Dohme LLC

Active, not recruiting

Riociguat in Children With Pulmonary Arterial Hypertension (PAH) (PATENT-CHILD)

Hypertension, Pulmonary

Germany, Turkey, Japan, Italy, Mexico, Poland, Hungary, Colombia, Taiwan
Daiichi Sankyo Co., Ltd.

Completed

Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension

Essential Hypertension

Japan
Daiichi Sankyo, Inc.

Completed

A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Hypertensive Subjects

Essential Hypertension

Japan
Daiichi Sankyo Co., Ltd.

Completed

Calcium Channel Blockers (CCBs) or Diuretics as an Add-on to Olmesartan Medoxomil in Hypertension

Hypertension

Japan
Daiichi Sankyo Co., Ltd.

Completed

Study of CS-3150 in Patients With Severe Hypertension

Severe Hypertension

Japan
Daiichi Sankyo Co., Ltd.

Completed

Study of CS-3150 Compared to Olmesartan in Patients With Essential Hypertension

Essential Hypertension

Japan
Novartis

Completed

Long Term Study of Valsartan and Amlodipine in Patients With Essential Hypertension (Extension to Study CVAA489A1301)

Hypertension

Japan
Novartis

Completed

A Study of VAH631 in Patients With Essential Hypertension (Factorial Study)

Hypertension

Japan
Tokyo University

Completed

Evaluation of Effect of Combination With Telmisartan and Hydrochlorothiazide in Hypertensives Uncontrolled on Amlodipine (ONEAST)

Essential Hypertension

Japan
Cook Group Incorporated

Completed

Zilver Flex Post-Market Study in Japan

Peripheral Arterial Disease (PAD)

Japan
Sanofi

Completed

Safety Evaluation of Clopidogrel Sulfate in Patients With Peripheral Arterial Disease

Peripheral Arterial Disease (PAD)

Japan
Satoshi Shizuta
Daiichi Sankyo Co., Ltd.; Research Institute for Production Development

Completed

Optimizing Antithrombotic Care in Patients With AtriaL fibrillatiON and Coronary stEnt (OAC-ALONE) Study (OAC-ALONE)

Coronary Artery Disease | Atrial Fibrillation

Japan
Daiichi Sankyo Co., Ltd.

Completed

Study of CS-3150 in Patients With Essential Hypertension (ESAX-HTN)

Essential Hypertension

Japan
Actelion

Active, not recruiting

Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) (A DUE)

Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)

United States, Japan, Taiwan, Turkey, Canada, China, Germany, Spain, Italy, Malaysia, Hungary, Russian Federation, Brazil, Australia, Bulgaria, Czechia, Mexico, Poland, South Africa
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study

Primary Open Angle Glaucoma or Ocular Hypertension

Japan

Clinical Trials on Refractory Arterial Hypertension in Japan

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