Clinical Trials on Refractory Colorectal Cancer in Singapore

Total 613 results

CytoMed Therapeutics Pte Ltd
National University Hospital, Singapore

Not yet recruiting

Allogeneic NKG2DL-targeting CAR γδ T Cells (CTM-N2D) in Advanced Cancers (ANGELICA)

Cancer | Malignancy | Relapsed Cancer | Refractory Cancer

Singapore
Paul Ong

Unknown

Feasibility Trial Evaluating Efficacy and Safety of Solitaire™ Thrombus Retrieval Device in the Management of Refractory Thrombus in Patients With Acute Coronary Syndrome (Solitaire)

Refractory Thrombus in Patients With Acute Coronary Syndrome

Singapore
National University Hospital, Singapore

Recruiting

Selinexor & Talazoparib in Advanced Refractory Solid Tumors; Advanced/Metastatic Triple Negative Breast Cancer (START)

Advanced Refractory Solid Tumors | Advanced Triple Negative Breast Cancers | Metastatic Triple Negative Breast Cancers

Singapore
National University Hospital, Singapore

Unknown

Clinical Evaluation - A Phase IIA Proof of Concept Study of Regorafenib (Bayer 73-4506) in Biopsy-amenable Asian Colorectal Cancer Patients

Asian Colorectal Cancer Patients

Singapore
Merck KGaA, Darmstadt, Germany
Merck Pte. Ltd., Singapore

Completed

Study Evaluating the Safety and Efficacy of FOLFIRI Plus Cetuximab or FOLFOX Plus Cetuximab as First-line Therapy in Subjects With KRAS Wild-type Metastatic Colorectal Cancer (APEC-Study) (APEC)

Metastatic Colorectal Cancer

Singapore
Singapore General Hospital
Singhealth Foundation

Completed

Pilot Study to Assess the Safety and Pharmacokinetics of 70-150μm Drug Eluting Beads Loaded With Irinotecan (DEBIRI).

Colorectal Cancer Metastatic

Singapore
National University Hospital, Singapore

Completed

A Phase II Study of Docetaxel Plus Carboplatin in Chemonaive Hormone-Refractory Prostate Cancer (HRPC) Patients

Hormone-Refractory Prostate Cancer

Singapore
National University Hospital, Singapore
Tan Tock Seng Hospital

Unknown

Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer

Rectal Cancers.

Singapore
National University Hospital, Singapore

Recruiting

Role of Circulating Tumour DNA Testing in Assessing for Alterations of Primary Anti-EGFR Resistance in RAS/RAF Wild-type Metastatic Colorectal Cancer Patients

Colorectal Cancer

Singapore
National Cancer Centre, Singapore
Merck Sharp & Dohme LLC

Recruiting

Window of Opportunity Study in Colorectal Cancer

Colorectal Cancer

Singapore
Changi General Hospital

Completed

Colorectal Cancer Prehabilitation in Changi General Hospital

Colorectal Cancer

Singapore
National University Health System, Singapore

Completed

Uncovering the Barriers of Colorectal Cancer Screening Amongst Siblings of Colorectal Cancer Patients.

Colorectal Cancer

Singapore
National University Hospital, Singapore
Otsuka Pharmaceutical Co., Ltd.

Unknown

Phase IIa Dose-Expansion and Biomarker Study of OPB-111077

NPC | Refractory Tumor

Singapore
AB Science

Terminated

Masitinib in Combination With FOLFIRI for Second-line Treatment of Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

France, Singapore, United Kingdom
National University Hospital, Singapore

Unknown

Verification of a Pharmacogenetic Approach to Customizing Chemotherapy to Asians

Colorectal Cancer

Singapore
National Medical Research Council (NMRC), Singapore

Unknown

Comparison of Two Types of Surgery in Treating Patients With Rectal Cancer

Colorectal Cancer

China, Singapore
MiRXES Pte Ltd

Recruiting

Project CADENCE (CAncer Detected Early caN be CurEd) (CADENCE)

Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Thoracic Cancer | Liver Cancer

Singapore
National Cancer Centre, Singapore
Bristol-Myers Squibb

Recruiting

Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC

Hepatocellular Carcinoma | Colorectal Cancer | Liver Metastases | Colorectal Carcinoma | Hepatocellular Cancer

Singapore
Singapore General Hospital

Completed

Randomized Trial of Colonic Stents as a Bridge to Surgery

Colorectal Cancer | Intestinal Obstruction

Singapore
National Cancer Centre, Singapore
Novartis

Terminated

Study of TKI 258 in Combination With Xeloda and Oxaliplatin in Advanced Colorectal and Gastric Cancer

Gastric Cancer | Colorectal Cancer

Singapore
National University Health System, Singapore

Recruiting

Uncovering and Overcoming the Barriers of Colorectal Cancer Screening Amongst Spouses of Patients With Colorectal Cancer

Colorectal Cancer

Singapore
National Cancer Centre, Singapore

Recruiting

Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma

Colorectal Cancer | Pancreatic Adenocarcinoma

Singapore
National Cancer Centre, Singapore

Unknown

Prophylactic HIPEC for Colorectal Cancers at High Risk of Developing Peritoneal Metastases

Colorectal Cancer | Peritoneal Metastases

Singapore
National University Hospital, Singapore

Unknown

A Study of Radiotherapy in Rectal Cancer Using Oxaliplatin, Capecitabine With or Without Cetuximab

Rectal Cancer

Singapore
National University Hospital, Singapore

Unknown

Safety Study of Conventional Versus Micropulse Transscleral Cyclophotocoagulation in Treating End-Stage Glaucoma

Advanced Glaucoma | Refractory Glaucoma

Singapore
National University Hospital, Singapore

Unknown

A Study of Lymphangiogenesis in Colorectal and Nasopharyngeal Cancer

Nasopharyngeal Cancer | Colorectal Cancer

Singapore
National University Hospital, Singapore

Unknown

Selecting Chemotherapy With High-throughput Drug Screen Assay Using Patient Derived Organoids in Patients With Refractory Solid Tumours (SCORE)

Colorectal Cancer | Epithelial Ovarian Cancer | HNSCC | Organoids

Singapore
Novartis Pharmaceuticals

Completed

Phase Ib Study of PDR001 in Combination With Regorafenib in Adult Patients With Previously Treated Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Spain, Italy, Singapore, Canada, Israel, Korea, Republic of, Netherlands, Australia
National University Hospital, Singapore
Prince of Wales Hospital, Shatin, Hong Kong; Apollo Gleneagles Hospitals, Kolkata

Unknown

Safety and Efficacy of Using MASTER to Perform Endoscopic Submucosal Dissection in Human

Gastric Cancer | Colon Cancer

Singapore, India, China
Sanofi
Regeneron Pharmaceuticals

Completed

A Study of Aflibercept Versus Placebo With FOLFIRI in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin Chemotherapy (AFLAME)

Colorectal Cancer Metastatic

Taiwan, China, Hong Kong, Japan, Singapore
Duke-NUS Graduate Medical School
Singhealth Foundation

Completed

Effectiveness of a Psychosocial Intervention for Colorectal Cancer (EPIC)

Colorectal Neoplasms

Singapore
Array BioPharma

Completed

Study of WNT974 in Combination With LGX818 and Cetuximab in Patients With BRAF-mutant Metastatic Colorectal Cancer (mCRC) and Wnt Pathway Mutations

Metastatic Colorectal Cancer

United States, Australia, Belgium, Canada, France, Israel, Italy, Netherlands, Singapore, Spain
Novartis Pharmaceuticals

Active, not recruiting

A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

BRAF V600 Colorectal Cancer

Belgium, Germany, Netherlands, Spain, Singapore, Australia, United Kingdom, Israel, Canada, United States
Novartis Pharmaceuticals

Recruiting

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (KontRASt-03)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Colorectal Cancer | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Carcinoma, Non-Small Cell Lung | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal | Non-Small Cell Lung Carcinoma | KRAS G12C Mutant Solid Tumors

Korea, Republic of, Spain, Belgium, United States, France, Germany, Italy, Singapore
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Ifosfamide and Doxorubicin in Patients With Refractory Nasopharyngeal Carcinoma

Refractory Nasopharyngeal Carcinoma

Singapore
National Cancer Centre, Singapore
Merck Sharp & Dohme LLC; National Medical Research Council (NMRC), Singapore

Not yet recruiting

Pembrolizumab and Olaparib Treatment for Relapsed or Refractory Peripheral T-Cell Lymphoma (POLAR)

Refractory Peripheral T-Cell Lymphoma | Relapsed Peripheral T-Cell Lymphoma

Singapore
Yisheng Biopharma (Singapore) Pte. Ltd.

Completed

Dose Escalation and Cohort Expansion Study of YS-ON-001 in Patients With Advanced Solid Tumors

Cancer

Singapore
National University Hospital, Singapore

Unknown

Familial Cancer Registry and DNA Bank

Cancer

Singapore
National University Hospital, Singapore

Unknown

Study of Genetic Factors Other Than CYP2C9 and VKORC1 That Influence Warfarin Dose Requirements in a South-east Asian Population

Cancer

Singapore
National University Hospital, Singapore

Completed

Pyruvate Kinase Isoform M2 (PKM2) as a Possible Biomarker for Cancer

Cancer

Singapore
Duke-NUS Graduate Medical School

Recruiting

Marital Satisfaction and Sexual Health of Female Cancer Patients in Singapore (RISE)

Breast Cancer | Gynecologic Cancer

Singapore
Duke-NUS Graduate Medical School
National University Hospital, Singapore; National Cancer Centre, Singapore

Active, not recruiting

Cost and Medical Care of Patients With Advanced Serious Illness in Singapore (COMPASS) Study (COMPASS)

Cancer

Singapore
National Cancer Centre, Singapore
Duke-NUS Graduate Medical School

Completed

Pilot Study of the SPaRK (Supportive and Palliative Care Review Kit) Model of Care for Advanced Cancer Patients Who Have an Unplanned Admission to Singapore General Hospital (SPaRK)

Cancer

Singapore
National University Hospital, Singapore

Unknown

Pharmacogenetic DNA Bank

Cancer

Singapore
National University Hospital, Singapore

Unknown

Transcriptomal and Molecular Characterization of Tumor Associated Monocytes/Macrophages in Human Cancers

Cancer | Tumor

Singapore
National University Hospital, Singapore

Unknown

The Optimization of 5-Fluorouracil Dose by Pharmacokinetic Monitoring in Asian Patients With Advanced Stage Cancer

Cancer (Advanced Stage)

Singapore
National University Hospital, Singapore

Recruiting

Integrated Molecular Analysis of Cancer (IMAC)

Cancer

Singapore
National Cancer Centre, Singapore
Ministry of Health, Singapore

Completed

Novel Palliative Care Model for Advanced Cancer Patients: A Randomized Controlled Trial Study (SPARKLE2)

Cancer

Singapore
National University Hospital, Singapore

Unknown

StrataXRT vs Standard Clinical Practice for the Prevention of Acute Dermatitis in Head and Neck Cancers Patients

Head and Neck Cancers | Acute Radiation Dermatitis

Singapore
National University Hospital, Singapore

Unknown

A Retrospective Immunohistochemistry Study of the Expression of Glycine/ Serine Pathway Molecules in Solid Tumors

Solid Tumor Cancer

Singapore

Clinical Trials on Refractory Colorectal Cancer in Singapore

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