Clinical Trials on Refractory Neoplasm in Netherlands

Total 3871 results

Lupin Ltd.

Completed

A Study of LNP3794 in Subjects With NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid Tumors

NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid Tumors

United Kingdom, Netherlands, Belgium
Radboud University Medical Center
Bayer

Completed

Phase 1 Study With Sorafenib and Sirolimus

Advanced Solid Tumor | Refractory to Standard Therapies

Netherlands
Princess Maxima Center for Pediatric Oncology

Recruiting

International Leukemia Target Board (iLTB)

Refractory Hematologic Malignancy | Relapsed Hematologic Malignancy

Netherlands
Skyline Diagnostics BV
Illumina, Inc.

Terminated

Accuracy Testing of the Chromosomal Aberration and Gene Mutation Markers of the AMLProfiler

Acute Myeloid Leukemia (AML) | Acute Promyelocytic Leukemia (APL) | Refractory Anemia With Excess of Blasts (RAEB)

United States, Germany, Netherlands, United Kingdom
Radboud University Medical Center
Dutch Cancer Society

Recruiting

Natural Killer-cell Therapy for Acute Myeloid Leukemia (NK4AML)

Acute Myeloid Leukemia Refractory | Acute Myeloid Leukemia, Relapsed, Adult

Netherlands
Maxima Medical Center

Terminated

A Multi-Centre RCT of the Axium® Neurostimulator for the Treatment of Chronic Inguinal Pain Following Surgery (SMASHING)

Chronic Inguinal Pain Refractory to Previous Surgical Intervention (Neurectomy)

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART B)

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic...

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART C)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (HEM-iSMART A)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies (HEM-iSMART D)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
UMC Utrecht
Rudolf Magnus Institute - University of Utrecht

Unknown

A New Method for Delineation of Epileptic Brian Tissue During Epilepsy Surgery (The HFO Study)

Refractory Localization-related Epilepsy

Netherlands
UMC Utrecht

Unknown

REC2Stim as a Treatment for Refractory Epilepsy in the Primary Sensorimotor Cortex. (REC2Stim)

Epilepsy Intractable | Epileptic Seizure | Motor Seizure

Netherlands
Medispec
Academisch Ziekenhuis Maastricht

Completed

Extracorporeal Shockwave Therapy for the Treatment of Advanced Angina Pectoris

Refractory Angina Pectoris

Netherlands
University of Oxford
Astellas Pharma Inc; European Organisation for Research and Treatment of Cancer... and other collaborators

Completed

Eurosarc Trial of Linsitinib in Advanced Ewing Sarcoma (LINES)

Refractory Ewing Sarcoma | Relapsed Ewing Sarcoma

United Kingdom, Germany, Netherlands, Italy, France
Epilepsiecentrum Kempenhaeghe
Maastricht University Medical Center

Unknown

Does VNS Interact With the Serotonergic and Immune System in Children With Intractable Epilepsy?

Refractory Epilepsy in Children

Netherlands
DeuterOncology

Recruiting

Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours

Adult Solid Tumor | Lung Cancer | Advanced Solid Tumor | Non-small Cell Lung Cancer | Non-small Cell Carcinoma | Refractory Tumor | Hereditary Renal Papillary Cancer

France, Belgium, Netherlands
Janssen Research & Development, LLC

Approved for marketing

Pre-Approval Access Program for Talquetamab in Relapsed or Refractory Multiple Myeloma

Relapsed or Refractory Multiple Myeloma

Brazil, Germany, Italy, Netherlands, Romania, Switzerland, United Kingdom
Gustave Roussy, Cancer Campus, Grand Paris
Innovative Therapies For Children with Cancer Consortium

Terminated

Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
Catharina Ziekenhuis Eindhoven

Recruiting

Efficacy of Spinal Cord Stimulation in Patients With Refractory Angina Pectoris (SCRAP)

Refractory Angina Pectoris | Spinal Cord Stimulation

Netherlands
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
Amgen

Terminated

A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies

Myelodysplastic Syndrome | Relapsed/Refractory AML | Minimal Residual Disease Positive AML

United States, Canada, Germany, Netherlands
European Hematology Association - Lymphoma Group
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Associazione...

Recruiting

Towards Personalized Medicine for Refractory/Relapsed Follicular Lymphoma Patients: the Cantera/Lupiae Registry (LUPIAE)

Follicular Lymphoma | Relapsed/Refractory Follicular Lymphoma

Spain, Netherlands, Italy, Croatia, Portugal, Ukraine
Maastricht Radiation Oncology

Completed

Radiomics for Prediction of Long Term Survival and Local Failure After Stereotactic Radiotherapy for Brain Metastases

Metastases, Neoplasm

Netherlands
Marjolein Spiering
Millennium: The Takeda Oncology Company

Unknown

Phase I/II Feasibility Study Combining Brentuximab Vedotin With Second Line Salvage Chemotherapy (DHAP) in Hodgkin Lymphoma Patients

Hodgkin Lymphoma | Relapse | Refractory

Netherlands, France, Denmark, United Kingdom
Novartis Pharmaceuticals

Completed

A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors

Advanced Solid Tumors | Recurrent or Refractory Medulloblastoma | Locally Advanced or Metastatic Basal Cell Carcinoma

United States, United Kingdom, Switzerland, Netherlands
UMC Utrecht

Completed

Single Dose Ablative Radiation Treatment for Early-Stage Breast Cancer (ABLATIVE)

Breast Neoplasm

Netherlands
Boston Scientific Corporation

Completed

WallFlex Esophageal Fully Covered (FC) Benign Anastomotic Stricture (E7025)

Refractory Anastomotic Esophageal Strictures

Netherlands, Sweden, Brazil
Amsterdam UMC, location VUmc

Completed

Tumor Kinase Inhibitor Concentrations Measured by PET (PIKTURE)

Disseminated Malignant Neoplasm

Netherlands
Kite, A Gilead Company

Recruiting

Study of Brexucabtagene Autoleucel in Adults With Rare B-cell Malignancies (ZUMA-25)

Relapsed/Refractory Waldenstrom Macroglobulinemia | Relapsed/Refractory Richter Transformation | Relapsed/Refractory Burkitt Lymphoma | Relapsed/Refractory Hairy Cell Leukemia

United States, Spain, Germany, Italy, France, Netherlands, Switzerland, Austria
Maastricht Radiation Oncology

Terminated

Tumor Hypoxia With HX4 PET in Several Diseases (HX4 SD)

Prostatic Neoplasms | Esophageal Neoplasms | Rectal Neoplasms | Brain Neoplasm, Primary | Neoplasm Metastases, Brain

Netherlands
Maruho Co., Ltd.

Completed

Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVIN

Usual Type Vulval Intraepithelial Neoplasia (uVIN)

Netherlands
Maastricht University Medical Center

Terminated

Reduced Contrast Administration in Contrast-enhanced Spectral Mammography (CESM)

Breast Neoplasm | Contrast-enhanced Spectral Mammography

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Confocal Laser Endomicroscopy in the Lower Urinary Tract

Urothelial Carcinoma | Bladder Neoplasm

Netherlands
Radboud University Medical Center

Completed

Lutetium-177-PSMA-617 in Low Volume Metastatic Prostate Cancer

Prostate Neoplasm

Netherlands
The Netherlands Cancer Institute
Erasmus Medical Center; Amsterdam University Medical Centres (AUMC)

Active, not recruiting

Prospective Clinical Validation of a Novel Multitarget FIT in CRC Screening (mtFIT)

CRC | Advanced Neoplasia

Netherlands
AvenCell Europe GmbH
Allucent (NL) BV

Recruiting

Dose-escalating Trial With Allo-RevCAR01-T Cells in Combination With CD123 Target Module (R-TM123) for Participants With Selected Hematologic Malignancies Positive for CD123

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

Germany, Netherlands
UMC Utrecht

Withdrawn

Stereotactic Body Radiotherapy Followed by Surgical Stabilization in Spinal Metastases (BLEND-II)

Neoplasm Metastasis | Surgery | Spinal Neoplasms | Radiosurgery

Netherlands
dr. M.P. van den Tol MD PhD

Completed

PET-MRI After Radiofrequency Ablation (RFA) or Microwave Ablation (MWA)

Liver Neoplasms | Local Neoplasm Recurrence

Netherlands
University Medical Center Groningen

Active, not recruiting

ImmunoPET With an Anti-CD8 Imaging Agent

Metastatic Cancer | Unresectable Malignant Neoplasm

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Regorafenib in Combination With Paclitaxel in Advanced Oesophagogastric Carcinoma (REPEAT)

Stomach Neoplasms | Neoplasm Metastasis | Esophageal Neoplasms

Netherlands
Kite, A Gilead Company

Recruiting

Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

Relapsed and/or Refractory B-cell Lymphoma

United States, Netherlands, United Kingdom, Germany
Millennium Pharmaceuticals, Inc.

Completed

Study of Brentuximab Vedotin (SGN-35) in Pediatric Participants With Relapsed or Refractory (r/r) Systemic Anaplastic Large-Cell Lymphoma or Hodgkin Lymphoma

Relapsed or Refractory Hodgkin Lymphoma | Relapsed or Refractory Anaplastic Large-cell Lymphoma

United States, France, United Kingdom, Germany, Spain, Netherlands, Italy, Mexico
UMC Utrecht

Unknown

Surefire Infusion System vs. Standard Microcatheter Use During Holmium-166 Radioembolization (SIM)

Liver Diseases | Digestive System Neoplasms | Neoplasm Metastasis | Colorectal Neoplasms

Netherlands
The Netherlands Cancer Institute
University Medical Center Groningen; UMC Utrecht; Erasmus Medical Center; Catharina...

Recruiting

Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination. (PERISCOPEII)

Peritoneal Carcinomatosis | Stomach Neoplasm

Netherlands
Meander Medical Center

Completed

Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Intravenous Bevacizumab-800CW (IBIZA-2)

Colorectal Neoplasms | Sentinel Lymph Node | Colon Neoplasm | Fluorescence

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celgene Corporation

Completed

The Addition of Nab-paclitaxel (Abraxane) to First Line Treatment of Metastasized Oesophagogastric Carcinoma (ACTION) (ACTION)

Esophageal Cancer | Toxicity

Netherlands
Radboud University Medical Center

Completed

Carcinoembryonic Antigen-loaded Dendritic Cells in Advanced Colorectal Cancer Patients

Colorectal Cancer | Liver Metastases

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Tapestry: Addition of TGF-β and PDL-1 Inhibition to Definitive Chemoradiation in Esophageal Squamous Cell Carcinoma (TAPESTRY)

Neoplasm, Esophageal | Neoplasm, Esophagus | Malignant Esophagus Tumor

Netherlands
Amsterdam UMC, location VUmc
UMC Utrecht; The Netherlands Cancer Institute

Terminated

Local Radiotherapy Following Complete Resection of a Brain Metastasis

Brain Neoplasms

Netherlands
UMC Utrecht

Completed

Radioactive Holmium Microspheres for the Treatment of Liver Metastases (HEPAR)

Liver Tumors | Liver Metastasis

Netherlands

Clinical Trials on Refractory Neoplasm in Netherlands

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