Clinical Trials on Refractory Neuroblastoma in Canada

Total 238 results

National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma

Recurrent Neuroblastoma | Refractory Neuroblastoma

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

Recurrent Neuroblastoma | Refractory Neuroblastoma | High Risk Neuroblastoma

United States, Canada, Puerto Rico, Australia, New Zealand
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Refractory Neuroblastoma | High Risk Neuroblastoma | Resectable Osteosarcoma

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI); Pfizer

Completed

Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Refractory Anaplastic Large Cell Lymphoma | Recurrent Childhood Anaplastic Large Cell Lymphoma

United States, Canada
St. Jude Children's Research Hospital
Pfizer; Ipsen

Recruiting

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Refractory Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Peripheral Primitive Neuroectodermal Tumor | Recurrent Rhabdoid Tumor | Recurrent... and other conditions

United States, Canada
National Cancer Institute (NCI)

Completed

Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma

Recurrent Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Stage 4S Neuroblastoma | Ganglioneuroblastoma | Stage 2A Neuroblastoma | Stage 2B Neuroblastoma | Stage 3 Neuroblastoma | Stage 4 Neuroblastoma | Stage 1 Neuroblastoma | Stage 2 Neuroblastoma

United States, Canada, Australia, New Zealand
National Cancer Institute (NCI)

Completed

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Refractory Malignant Solid Neoplasm | Recurrent Melanoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditions

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma

Recurrent Neuroblastoma | Stage 4S Neuroblastoma | Stage 2A Neuroblastoma | Stage 2B Neuroblastoma | Stage 3 Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
National Cancer Institute (NCI)

Active, not recruiting

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Ganglioneuroblastoma | Stage 4 Neuroblastoma

United States, Puerto Rico, Canada, Australia, New Zealand, Netherlands, Saudi Arabia, Switzerland
National Cancer Institute (NCI)

Completed

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Pineoblastoma | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Rhabdomyosarcoma | Refractory Medulloblastoma | Refractory Neuroblastoma | Refractory Rhabdomyosarcoma | Central Nervous System Embryonal Tumor With... and other conditions

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment

Recurrent Neuroblastoma | Disseminated Neuroblastoma

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma

Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma

United States, Canada, Australia
National Cancer Institute (NCI)

Withdrawn

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Hematopoietic and Lymphoid Cell Neoplasm | Lynch Syndrome | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central... and other conditions

United States, Canada
Giselle Sholler
Y-mAbs

Recruiting

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

High-risk Neuroblastoma

United States, Canada
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Relapsed Solid Tumor | Refractory Solid Tumor

United States, Canada, France, Australia, Belgium, Germany, Spain, Italy
Centre de recherche du Centre hospitalier universitaire...

Recruiting

68Ga-DOTATATE Neuroblastoma Imaging Pilot

Neuroblastoma

Canada
McGill University

Recruiting

Using Micro-filaments to Detect "Fast Ripples" and Improve the Identification of the Epileptogenic Zone (NeuroSeizure)

Epilepsy, Refractory

Canada
University of Calgary

Unknown

Voronistat in Pediatric Patients With Drug Resistant Epilepsy

Refractory Epilepsy

Canada
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand
NCIC Clinical Trials Group
Geron Corporation

Withdrawn

Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma

Neuroblastoma

Canada
Stanford University
Amgen; Pediatric Oncology Experimental Therapeutics Investigators' Consortium

Completed

Carfilzomib in Combination With Cyclophosphamide and Etoposide for Children (POE14-01)

Refractory Leukemia | Refractory Solid Tumors | Relapsed Solid Tumors | Relapsed Leukemia

United States, Canada
National Cancer Institute (NCI)

Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Malignant Glioma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent... and other conditions

United States, Puerto Rico, Australia, Canada
University Health Network, Toronto
Takara Bio Inc.

Recruiting

Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL

Relapsed or Refractory Chronic Lymphocytic Leukemia | Relapsed or Refractory Small Lymphocytic Lymphoma | Relapsed or Refractory CD19+ B-cell Lymphoma

Canada
The Canadian College of Naturopathic Medicine
University Health Network, Toronto; North York General Hospital; Ontario Brain...

Terminated

Clinical Trial of the Effects of DHA in the Treatment of Seizure Disorders

Epilepsy (Treatment Refractory)

Canada
CASI Pharmaceuticals, Inc.

Completed

Study of ENMD-2076 in Patients With Relapsed or Refractory Hematological Malignancies

Relapsed or Refractory Hematological Malignancies

Canada
University Health Network, Toronto
AbbVie; Celgene

Terminated

Study of Enasidenib and Venetoclax in IDH2-Mutated Blood Cancers

Acute Myeloid Leukemia | Relapsed Cancer | Refractory Cancer | IDH2 Gene Mutation

Canada
Clinique des Céphalées de Montréal

Completed

Treatment of Chronic Migraine With Erenumab Alone or as an Add on Therapy

Refractory Chronic Migraine

Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma

Recurrent Neuroblastoma

United States, Canada
Joel Town
Nova Scotia Health Authority

Completed

Halifax Treatment Refractory Depression Trial

Depression

Canada
University of Alberta

Completed

Efficacy of Ketamine in Post Anesthesia Recovery Room

Pain, Postoperative | Pain, Acute | Pain, Intractable | Ketamine Adverse Reaction | Pain, Refractory

Canada
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Mantle Cell Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Refractory Marginal Zone Lymphoma | Recurrent Lymphoplasmacytic... and other conditions

United States, Canada
Medispec
KMH Cardiology and Diagnostic Centres

Suspended

Extracorporeal Shockwave Therapy for the Treatment of Chronic Angina Pectoris

Refractory Angina Pectoris

Canada
Centre for Addiction and Mental Health
National Alliance for Research on Schizophrenia and Depression; Canadian Institutes... and other collaborators

Completed

Repetitive Transcranial Magnetic Stimulation for Refractory Auditory Hallucinations in Schizophrenia

Refractory Schizophrenia

Canada
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Doses of AGS67E Given as Monotherapy in Subjects With Refractory or Relapsed Lymphoid Malignancies

Relapsed Lymphoid Malignancy | Refractory Lymphoid Malignancy

United States, Canada
National Cancer Institute (NCI)
United Therapeutics

Completed

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

Recurrent Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico
University Health Network, Toronto

Recruiting

Study of Pembrolizumab With Bendamustine in Hodgkin Lymphoma

Classical Hodgkin Lymphoma | Relapsed Cancer | Refractory Cancer

Canada
Abbott Medical Devices

Completed

HeartMate 3 CE Mark Study Long Term Follow-up (HM3 CE LTFU)

Advanced Refractory Left Ventricular Heart Failure

Germany, Canada, Austria, Czechia, Kazakhstan, Australia
University of Alberta
Novartis

Completed

The Use of Drugs to Improve Kidney Function in Patients With Liver and Kidney Dysfunction

Refractory Ascites | Type 2 Hepatorenal Syndrome

Canada
Instituto de Investigacion Sanitaria La Fe

Completed

European Low and Intermediate Risk Neuroblastoma Protocol

LOW AND INTERMEDIATE PAEDIATRIC NEUROBLASTOMA AND NEONATAL SUPRARENAL MASSES

Spain, Italy, Belgium, Denmark, Sweden, Norway, Israel, Switzerland, Australia, Austria
Onconova Therapeutics, Inc.

Terminated

Controlled Study of Rigosertib Versus Physician's Choice of Treatment in MDS Patients After Failure of an HMA (INSPIRE)

Myelodysplastic Syndrome | MDS | Refractory Anemia With Excess Blasts | RAEB

United States, Spain, Canada, France, Australia, Switzerland, Israel, Japan, Belgium, India, Ireland, United Kingdom, Croatia, Czechia, Poland, Estonia, Germany, Italy, Austria, Hungary, Russian Federation, Sweden
Alberta Health services
Pfizer

Unknown

Sutent Maintenance After Response to Taxotere (SMART)

Prostate Cancer | Hormone Refractory

Canada
Seattle Children's Hospital
Children's Healthcare of Atlanta; Pediatric Oncology Experimental Therapeutics...

Completed

POETIC Plerixafor as a Chemosensitizing Agent for Relapsed Acute Leukemia and MDS in Pediatric Patients

AML | Acute Leukemia of Ambiguous Lineage | ALL | Relapsed/Refractory AML | Relapsed/Refractory ALL | Secondary AML/MDS

United States, Canada
AHS Cancer Control Alberta
Tom Baker Cancer Centre

Terminated

GEMHDM2014 : Gem-HDM HDT and ASCT for Relapsed/ Refractory Lymphoma (GEMHDM2014)

Follicular Lymphoma | Hodgkin's Lymphoma - Relapsed/Refractory | Non-Hodgkin's Lymphoma - Aggressive

Canada
British Columbia Cancer Agency
Canadian Urologic Oncology Group; German Testicular Cancer Study Group; NCIC...

Completed

Phase-II Study of SU011248 (Sunitinib)in Male Patients With Relapsed or Cisplatin-Refractory Germ Cell Cancer

Relapsed or Cisplatin-Refractory Germ Cell Cancer

Canada
Theralase Inc.
University Health Network, Toronto; WCCT Global; Medelis Inc.

Completed

Intravesical Photodynamic Therapy (PDT) in BCG Refractory High-Risk Non-muscle Invasive Bladder Cancer (NMIBC) Patients

Non-Muscle Invasive Bladder Cancer (NMIBC) Refractory to BCG

Canada
European Society for Blood and Marrow Transplantation
Mallinckrodt

Completed

ECP Combination Study

Steroid Refractory GVHD

Spain, United Kingdom, Sweden, Italy, Israel, France, Denmark, Germany, Poland, Turkey, Romania, Belgium, Greece, Russian Federation
Abbott Medical Devices
Thoratec Corporation; KCRI; Center for Life Sciences; Emergo

Completed

HeartMate 3™ CE Mark Clinical Investigation Plan (HM3 CE Mark)

Advanced Refractory Left Ventricular Heart Failure

Germany, Australia, Austria, Canada, Czechia, Kazakhstan

Clinical Trials on Refractory Neuroblastoma in Canada

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