Clinical Trials on Refractory Malignant Germ Cell Tumor

Total 11589 results

Rhizen Pharmaceuticals SA

Completed

Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, in Patients With Solid Tumors

Solid Tumor | Metastatic Breast Cancer | Locally Advanced Breast Cancer | Extensive-stage Small-cell Lung Cancer | Platinum-Sensitive Fallopian Tube Carcinoma | Platinum-sensitive Ovarian Cancer | Platinum-Sensitive Peritoneal Cancer

Czechia, Poland
NantCell, Inc.
Takeda

Terminated

QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas (GAMMA)

Cancer | Pancreatic Cancer | Advanced Solid Tumors | Metastatic Cancer | Bone Metastases | Solid Tumors | Pancreas Cancer | Adenocarcinoma of the Pancreas | Oncology | Cancer of Pancreas | Metastatic Pancreatic Cancer | Metastases | Cancer of the Pancreas | Advanced Malignancy | Oncology Patients | Endocrine Cancer

Italy, Spain, United Kingdom, Belgium, Canada, Denmark, Romania, United States, Germany, Netherlands, Korea, Republic of, Russian Federation, Australia, Austria, Lithuania, Portugal, Greece, Poland, Switzerland, Serbia, Bulgaria, ... and more
West China Hospital
Sun Yat-sen University; Cancer Hospital of China Medical University, Liaoning... and other collaborators

Recruiting

A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients (proOMCRC)

Colorectal Cancer | Ovarian Metastasis

China
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom; Alder Hey Children's...

Recruiting

Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP) (AIR:RRP)

Human Papilloma Virus | Recurrent Respiratory Papillomatosis

United Kingdom
Memorial Sloan Kettering Cancer Center

Active, not recruiting

In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignancies

Lymphoma | Acute Lymphocytic Leukemia

United States
Kaiser Permanente
National Cancer Institute (NCI); University of Washington; University of Texas...

Completed

Self-Testing Options in the Era of Primary HPV Screening for Cervical Cancer Trial (STEP)

Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Cervical Cancer | Uterine Neoplasms | Genital Neoplasms, Female | Uterine Cervical Diseases | Uterine Diseases | HPV-Related Malignancy | HPV Infection | HPV-Related Cervical Carcinoma | Human Papilloma Virus | Uterine Cervical Neoplasm | Cervical Dysplasia

United States
Queen Mary University of London

Recruiting

THERApy De-escalation for TESTicular Cancer (THERATEST)

Seminoma

United Kingdom
Swiss Group for Clinical Cancer Research
German Testicular Cancer Study Group

Active, not recruiting

Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma

Seminoma | Testicular Cancer

Germany, Switzerland
University Hospital, Montpellier
Centre Hospitalier Universitaire de Nīmes; Institut du Cancer de Montpellier... and other collaborators

Recruiting

Research of Circulating Tumor Cells Released During Cervical Cancer Surgery (CTC-COL)

Cervical Cancer Stage IB2 | Cervical Cancer Stage IB1 | Cervical Cancer Stage IA1 | Cervical Cancer Stage IA2

France
Third Military Medical University

Unknown

Application of Detecting Circulating Tumor Cells in the Accurate Treatment of Early Stage Lung Adenocarcinoma (CTCs detection)

Treatment | Diagnoses Diseases | Lung Adenocarcinoma, Stage I | Circulating Tumor Cells

China
KU Leuven
Agentschap voor Innovatie door Wetenschap en Technologie; Research Foundation...

Completed

Perioperative Cancer Cell Dissemination and Systemic Immune Suppression in Resectable Ductal Pancreatic Adenocarcinoma

Adenocarcinoma | Pancreatic Neoplasms | Monitoring, Immunologic | Neoplasm Circulating Cells | Tumor Markers, Biological

Belgium
National Cancer Institute (NCI)
NRG Oncology

Completed

Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Endometrioid Adenocarcinoma | Ovarian Undifferentiated Carcinoma | Fallopian Tube Carcinoma | Ovarian Carcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Mucinous Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube Clear Cell... and other conditions

United States
Eli Lilly and Company

Completed

A Study of LY2875358 in Japanese Participants With Advanced Cancer

Lymphoma | Carcinoma, Non-Small-Cell Lung | Solid Tumors

Japan
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Completed

Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery

Melanoma | Soft Tissue Sarcoma | Renal Cell Carcinoma | Spinal Cord Compression | Metastatic Malignant Neoplasm in the Spine

United States
Morphotek

Completed

A Study of MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancer

Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Mesothelioma

United States
National Cancer Institute (NCI)

Completed

Tanespimycin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, or Myelodysplastic Syndromes

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia... and other conditions

United States
Alaunos Therapeutics

Unknown

Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With Malignancies

Cancer | Small Cell Lung Cancer | Ovarian Cancer | Thymoma | Osteosarcoma | Non Small Cell Lung Cancer | Malignancy | Testicular Cancer

United States
Immunovative Therapies, Ltd.
Hadassah Medical Organization

Completed

A Phase I/II Study of Mis-Matched Immune Cells (AlloStim) in Patients With Advanced Hematological Malignancy

Lymphoma | Leukemia | Multiple Myeloma | Hematological Malignancy

Israel
Children's Hospital of Philadelphia
Jazz Pharmaceuticals; Stand Up To Cancer

Recruiting

Lurbinectedin in FET-Fused Tumors (LiFFT)

Ewing Sarcoma | Pediatric Cancer | Desmoplastic Small Round Cell Tumor | Undifferentiated Sarcoma

United States
Labo'Life

Recruiting

Study of 2LPAPI® on the Clearance of Genital HR-HPV Infections. (PAPION)

Human Papilloma Virus

Belgium
M.D. Anderson Cancer Center

Completed

Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor

Sarcoma | Advanced Cancers

United States
M.D. Anderson Cancer Center

Completed

Rituximab and Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) for Burkitt's and Burkitt's -Like Leukemia/Lymphoma

Burkitt's Lymphoma | Burkitt'S-like Lymphoma

United States
Seoul National University Hospital
Gilead Sciences; Konkuk University Hospital

Unknown

To Compare the Efficacy of a Prophylactic Use of Tenofovir by Duration for the Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma, Burkitt's

Korea, Republic of
Roswell Park Cancer Institute
National Cancer Institute (NCI); Novartis

Withdrawn

Dovitinib Lactate, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Solid Tumors or Pancreatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
IGM Biosciences, Inc.

Recruiting

Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants With Relapsed, Refractory, or Newly Diagnosed Cancers

Sarcoma | Acute Myeloid Leukemia | Colorectal Cancer | Solid Tumor | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Chondrosarcoma | Small Lymphocytic Lymphoma

United States, Korea, Republic of, France, Spain, Australia
Stephen E. Goldstone

Unknown

A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand

Anal Cancer | Human Papillomavirus Infection | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | HPV-Related Squamous Cell Carcinoma | Ain III

United States
Kymera Therapeutics, Inc.

Recruiting

Safety and Clinical Activity of KT-253 in Adult Patients With High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Advanced Solid Tumors | Acute Lymphocytic Leukemia | Lymphomas | Myeloid Malignancies

United States
Hadassah Medical Organization
Vaxil Therapeutics Ltd.

Withdrawn

A Novel Vaccine for the Treatment of MUC1-expressing Tumor Malignancies

Multiple Myeloma | Tumors

Israel
Case Comprehensive Cancer Center

Completed

High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States
Fox Chase Cancer Center

Completed

A Dose-Escalation Study of Onc201 Administered Every One or Three Weeks in Advanced Solid Tumors and Multiple Myeloma

Multiple Myeloma | Advanced Solid Tumors

United States
Acceleron Pharma Inc. (a wholly owned subsidiary...

Completed

Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma

Multiple Myeloma | Advanced Solid Tumors

United States
University of California, San Francisco

Terminated

Pilot Trial of Clofarabine Added to Standard Busulfan and Fludarabine for Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Myeloid Malignancy | Metabolic Disease | Bone Marrow Failure Syndrome | Transfusion-dependent Red Blood Cell (RBC) Defect | Congenital Immunodeficiency | Severe Immune Dysregulation

United States
Northwestern University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
Centro di Riferimento Oncologico - Aviano

Recruiting

Study for Validation of Target Therapy in Multiple Myeloma Cells From Patients With miRNAs Released From B Cells, and Study of the Bone Marrow Tumor Microenvironment (Microenvironment of MM)

Multiple Myeloma

Italy
Beijing Friendship Hospital

Not yet recruiting

L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLH

Lymphoma | Hemophagocytic Lymphohistiocytosis | PD-1 Antibody | Epstein-Barr Virus

China
Ruth Tachezy, PhD.
Na Homolce Hospital; Medical Healthcom Prague

Completed

Effect of Vaccination in Patients With Recurrent Respiratory Papillomatosis

Squamous Papilloma of the Larynx

Czechia
Northern Italy Leukemia Group

Completed

Chemotherapy Plus Rituximab Combination for Adult Lymphoblastic Leukemia (B-ALL) and Burkitt's Non-Hodgkin Lymphoma

Burkitt Lymphoma | B-ALL

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Phase I/II Study of Bosutinib in Combination With Inotuzumab Ozogamicin in CD22-positive PC Positive ALL and CML

Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | B Acute Lymphoblastic Leukemia With t(9;22)(q34... and other conditions

United States
Genmab
BioNTech SE

Active, not recruiting

GEN1046 Safety Trial in Patients With Malignant Solid Tumors

Cervical Cancer | Squamous Cell Carcinoma of the Head and Neck | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Solid Tumors | Endometrial Carcinoma | Urothelial Carcinoma

United States, Spain, Israel, Czechia, Georgia, Italy, Poland, Turkey, Hungary, Ukraine
Leaf Vertical Inc.

Unknown

A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies

Glioblastoma Multiforme | Cancer of Liver | Cancer of Pancreas | Cancer of Colon | Myeloma Multiple | Cancer of Rectum | Cancer, Gall Bladder

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

HIV Infection | Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal... and other conditions

United States
European Organisation for Research and Treatment...

Unknown

Study of Long-Term Outcomes of Patients With Acute Lymphoblastic Leukemia Who Were Enrolled as Children on Clinical Trials EORTC-58741, EORTC-58831, EORTC-58832, or EORTC-58881 Between 1971 and 1998

Leukemia | Cancer Survivor | Long-term Effects Secondary to Cancer Therapy in Children
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Completed

Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners

Stage IV Lung Cancer | Stage IV Skin Melanoma | Stage IIIB Skin Melanoma | Stage IIIC Skin Melanoma | Stage III Uterine Corpus Cancer | Stage IV Uterine Corpus Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Malignant Female Reproductive System Neoplasm | Stage III... and other conditions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Fox Chase Cancer Center

Recruiting

Analysis of Primary and Metastatic Tumors in Patients With Renal Cell Carcinoma and Urothelial Carcinoma

Renal Cell Carcinoma | Bladder Cancer | Urothelial Carcinoma | Ureter Cancer | Urethral Cancer

United States
Duke University

Completed

Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders

Hemoglobinopathies | Thalassemia | Lysosomal Storage Disease | Immunodeficiencies | Inborn Errors of Metabolism | Sickle Cell | Non Malignant Disorders | Congenital Marrow Failures

United States
MacroGenics

Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

Melanoma | Sarcoma | Clear Cell Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Advanced Solid Tumor | Endometrial Cancer | Small-cell Lung Cancer | Advanced... and other conditions

United States, Australia
Massachusetts General Hospital
Conquer Cancer Foundation

Recruiting

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy (PEACE)

Lymphoma | Leukemia | Multiple Myeloma | Hematologic Malignancy | Blood Cancer

United States
Asan Medical Center

Unknown

A Randomized Phase II Open Label Study to Compare the Safety and Efficacy of Subcutaneous Dalteparin Versus Direct Oral Anticoagulants for Cancer-associated Venous Thromboembolism (PRIORITY)

Stomach Cancer | Hepatocellular Carcinoma | Pancreatic Cancer | Esophageal Cancer | Duodenal Cancer | Esophagogastric Junction Cancer | Cancer-associated Thrombosis | Ampulla of Vater Cancer | Malignant Gastrointestinal Stromal Tumor | Biliary Cancer (Cholangiocarcinoma, Gall Bladder Cancer)

Korea, Republic of
University of Pennsylvania

Recruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Parkinson Disease | Alzheimer Disease | ALS | Polyneuropathies | Frontotemporal Dementia | Pheochromocytoma | Thoracic Aortic Aneurysm | Paraganglioma | Genetic Predisposition | Cardiomyopathy Non-ischemic

United States

Clinical Trials on Refractory Malignant Germ Cell Tumor

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