Clinical Trials on Relapsed/Refractory Multiple Myeloma

Total 4799 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI); AstraZeneca

Active, not recruiting

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC... and other conditions

United States
Incyte Corporation

Recruiting

Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms (LIMBER)

Myelofibrosis | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome | Relapsed or Refractory Primary Myelofibrosis | Secondary Myelofibrosis (Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis) | ET...

United States, Spain, Japan, Italy, Finland, United Kingdom, Canada
University Hospital, Strasbourg, France

Recruiting

Growth Curves in Cockayne Syndrome Type 1 and Type 2 (Curves-CS)

Cockayne Syndrome, Type I and II

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

A Phase I Study of SOR-C13 in Patients With Advanced Solid Tumors

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Stage IV Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB... and other conditions

United States
Telios Pharma, Inc.

Active, not recruiting

Phase I/II, FIH, Dose Escalation Trial of TL-895 and Expansion of TL-895 Monotherapy and Combination Therapy With Navtemadlin in Tx-Naïve and R/R CLL/SLL Subjects

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Relapsed/Refractory B Cell Malignancies | Mantle Cell Lymphoma and Diffuse Large B Cell Lymphoma | Treatment-Naive B Cell Malignancies

United States, Poland, Ukraine, Hungary, Italy, Russian Federation, United Kingdom
MingSight Pharmaceuticals, Inc
Shenzhen MingSight Relin Pharmaceutical Co., Ltd

Recruiting

A Study of MS-553 in Patients With Relapsed or Refractory B-cell Lymphoma

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Mantle Cell Lymphoma (MCL) | Diffuse Large B-cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Relapsed or Refractory B-cell Lymphoma | Marginal Zone Lymphoma (MZL)

China
M.D. Anderson Cancer Center

Active, not recruiting

A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma

Recurrent Endometrial Carcinoma | Recurrent Endometrial Endometrioid Adenocarcinoma | Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Refractory Endometrial Carcinoma | Refractory... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Peritoneal Carcinomatosis | Malignant Peritoneal Neoplasm | Recurrent Endometrial Carcinoma | Stage IVB Uterine Corpus Cancer AJCC v8 | Recurrent Cervical Carcinoma | Metastatic Malignant Female... and other conditions

United States
National Eye Institute (NEI)

Recruiting

National Eye Institute Biorepository for Retinal Diseases

Age-Related Macular Degeneration | Diabetic Retinopathy | Retinal Vein Occlusion | Retinal Disease | Von Hippel-Lindau Syndrome

United States
National Institute of Dental and Craniofacial Research...

Terminated

Effects of PTH Replacement on Bone in Hypoparathyroidism

DiGeorge Syndrome | Hypoparathyroidism

United States
Heidelberg University

Completed

Glucose-dependent Asprosin Dynamics

Diabetes Mellitus

Germany
Amir Mortazavi
National Cancer Institute (NCI); Arno Therapeutics

Completed

AR-42 in Treating Patients With Advanced or Relapsed Multiple Myeloma, Chronic Lymphocytic Leukemia, or Lymphoma

Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
Sellas Life Sciences Group
Merck Sharp & Dohme LLC; Cancer Insight, LLC

Active, not recruiting

Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers

Colorectal Cancer | Ovarian Cancer | Acute Myelogenous Leukemia | Small-cell Lung Cancer | Triple-negative Breast Cancer

United States
Ohio State University Comprehensive Cancer Center
American Cancer Society, Inc.; Lance Armstrong Foundation

Completed

Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors (FOCUS)

Depression | Pain | Leukemia | Fatigue | Multiple Myeloma | Insomnia | Pancreatic Cancer | Esophageal Cancer | Lung Cancer | Glioblastoma Multiforme | Sleep Disorders | Uncertainty | Ovarian Neoplasm | Anxiety Disorder | Psychological Intervention | Relapsed Lymphoma | Worry | Cognitive-behavioral Therapy | Stage III or IV Cervical... and other conditions

United States
Robert Lowsky
National Cancer Institute (NCI)

Completed

Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies

Recurrent Adult Acute Myeloid Leukemia | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Immunoblastic Large... and other conditions

United States
Dignity Health Medical Foundation
Dolly Roy MD PhD (author); J. Michael Menke (statistician); Sabeen Lulu MD (Principal...

Not yet recruiting

Observational Trial Evaluating Elevated Factor VIII Related Labs as a Biomarker for Incomplete Relapse Recovery

Multiple Sclerosis | Relapse
Medical University of Warsaw

Completed

Assessment of CAI in Adults With PWS.

Prader-Willi Syndrome | Central Adrenal Insufficiency

Poland
Inner Group Inc.

Unknown

Hypnosis and Direct Autonomic Experience Influence on Chronic Symptoms (HDAX1)

Multiple Sclerosis | Restless Legs Syndrome | Trauma | Chronic Disease | Trauma, Psychological
Children's Healthcare of Atlanta

Terminated

Prevalence and Clinical Spectrum of the 22q11 Deletion

Congenital Disorders

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Recurrent Platinum-Resistant Ovarian Carcinoma | Refractory Ovarian Carcinoma

United States
N.N. Petrov National Medical Research Center of...

Recruiting

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations (NТО-RAS)

Melanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene Mutation

Russian Federation
Seoul National University Hospital
Pharos iBio Co., Ltd.

Recruiting

Chk2 Inhibitor for Recurrent EpitheliAl periToneal, fallopIan or oVarian cancEr (CREATIVE Phase IA Trial) (CREATIVE)

Platinum-resistant Ovarian Cancer | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-refractory Ovarian Carcinoma

Korea, Republic of
Bayer

Completed

Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

United States
University of Colorado, Denver

Completed

Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome

Respiratory Tract Infections | Down Syndrome | Polyendocrinopathies, Autoimmune | Autoimmunity

United States
Medical College of Wisconsin

Recruiting

Long-term Follow-up Study of Patients Receiving CAR-T Cells

Follicular Lymphoma | Multiple Myeloma | Burkitt Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Lymphoma, Small Lymphocytic | Diffuse Large B Cell Lymphoma | Central Nervous System Lymphoma | Lymphomas Non-Hodgkin's B-Cell

United States
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors

Stage IV Ovarian Cancer | Endometrial Cancer Recurrent | Testis Cancer, Refractory | CAR NK

China
Kang YU
CARsgen Therapeutics Co., Ltd.

Active, not recruiting

Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant Tumors

Hepatocellular Carcinoma | B Cell Lymphoma | Pancreatic Carcinoma | Myeloma | B Cell Leukemia | Adenocarcinoma of Esophagogastric Junction

China
Nationwide Children's Hospital

Completed

Diagnosis of Central Adrenal Insufficiency in Patients With Prader-Willi Syndrome

Adrenal Insufficiency | Prader Willi Syndrome

United States
University of Washington
National Cancer Institute (NCI)

Completed

Bendamustine Hydrochloride, Etoposide, Dexamethasone, and Filgrastim For Peripheral Blood Stem Cell Mobilization in Treating Patients With Refractory or Recurrent Lymphoma or Multiple Myeloma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions
Huazhong University of Science and Technology
Shanghai IASO Biotechnology Co., Ltd

Not yet recruiting

Safety and Efficacy of CT125A Cells for Treatment of Relapsed/Refractory CD5+ Hematopoietic Malignancies

Chronic Lymphocytic Leukemia (CLL) | Peripheral T-cell Lymphomas (PTCL) | CD5+ Relapsed/Refractory Hematopoietic Malignancies | Mantle Cell Lymphoma (MCL) | Diffuse Large B-cell Lymphoma (DLBCL) | Follicular Lymphoma (FL)
National Cancer Institute (NCI)

Completed

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Juvenile Myelomonocytic Leukemia | Recurrent Childhood Medulloblastoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Acute Promyelocytic Leukemia (M3) | Childhood Chronic Myelogenous Leukemia | Recurrent Childhood Acute Lymphoblastic... and other conditions

United States
Case Comprehensive Cancer Center

Completed

Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell... and other conditions

United States
University College London Hospitals

Completed

CAR T Cell Therapy Related Cardiovascular Outcomes (CARTCO)

Cardiovascular Diseases | Diffuse Large B Cell Lymphoma | Cardiotoxicity | B-cell Acute Lymphoblastic Leukemia | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | B-cell Lymphoma Refractory | Cardiovascular Complication | B-cell Lymphoma Recurrent

United Kingdom
Jagannadha R Avasarala

Terminated

Diagnosis of ON With or Without MS or NMOSD

Multiple Sclerosis | Optic Neuritis | Neuromyelitis Optica Spectrum Disorder Attack | Neuromyelitis Optica Spectrum Disorder Relapse | Neuromyelitis Optica Spectrum Disorder Progression

United States
Innovation Research & Training

Recruiting

Mindfulness Program for Adolescents With 22q11DS

22Q11 Deletion Syndrome

United States
Sumitomo Pharma Switzerland GmbH

Recruiting

Congenital Athymia Patient Registry

Complete DiGeorge Anomaly | Complete DiGeorge Syndrome | Congenital Athymia

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Parathyroid and Thymus Transplantation in DiGeorge #931

DiGeorge Syndrome | Hypoparathyroidism | Complete DiGeorge Syndrome

United States
Cyteir Therapeutics, Inc.

Active, not recruiting

A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors

Soft Tissue Sarcoma | Follicular Lymphoma | Breast Cancer | Head and Neck Cancer | Small Cell Lung Cancer | Multiple Myeloma | Pancreatic Cancer | Ovarian Cancer | Mantle Cell Lymphoma | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | DLBCL | Non-hodgkin Lymphoma | Malignancy | CLL

United States
M.D. Anderson Cancer Center

Recruiting

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Chondrosarcoma | Advanced Malignant Solid Neoplasm | Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous... and other conditions

United States
Center for International Blood and Marrow Transplant...
Sanofi; Genzyme, a Sanofi Company

Completed

A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor

Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Hodgkin's Disease | Related Donors Donating Peripheral Blood Stem Cells (PBSC) to a Family Member

United States
Taproot Health

Recruiting

The Registry of Oncology Outcomes Associated With Testing and Treatment (ROOT)

Melanoma | Sarcoma | Kidney Cancer | Adenocarcinoma | Renal Cell Carcinoma | Cervical Cancer | Acute Myeloid Leukemia | Stomach Cancer | Breast Cancer | Head and Neck Neoplasms | Nasopharyngeal Carcinoma | Glioblastoma | Astrocytoma | Multiple Myeloma | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer and other conditions

United States
Cedars-Sinai Medical Center
Walter Reed National Military Medical Center

Completed

The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors

Sarcoma | Neoplasms | Lymphoma | Lymphoma, Non-Hodgkin | Leukemia | Cancer | Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Glioblastoma | Multiple Myeloma | Colorectal Cancer | Hodgkin Lymphoma | Lung Cancer | Bone Cancer | Prostate Cancer | Brain Cancer | Skin Cancer | Pancreas Cancer | Gastrointestinal Cancer | Thyroid... and other conditions

United States
Hôpital le Vinatier

Recruiting

Arithmetic Abilities in Children With 22q11.2DS (ARITH22)

22q11.2 Deletion Syndrome

France
Nobias Therapeutics, Inc.

Completed

NB-001 in Children and Adolescents With 22q11 Deletion Syndrome

22q11 Deletion Syndrome

United States, Canada
University of Geneva, Switzerland

Completed

Effects of Methylphenidate on Brain and Cognition in 22q11 Deletion Syndrome

22q11.2 Deletion Syndrome

Switzerland
Hôpital le Vinatier

Terminated

Social Cognition Training and Cognitive Remediation (RCKID)

22q11.2 Deletion Syndrome

France
National Health Insurance Service Ilsan Hospital

Unknown

Long Term Prevention of Nausea and Vomiting in Gynecologic Laparoscopy (PONV)

Uterine Myoma, Ovary Neoplasm, Adenomyosis

Korea, Republic of
Gillian Gresham

Completed

Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients

Melanoma | Sarcoma | Neoplasms | Lymphoma | Kidney Cancer | Leukemia | Cancer | Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Glioblastoma | Multiple Myeloma | Stress | Colorectal Cancer | Anxiety | Lung Cancer | Prostate Cancer | Bladder Cancer | Loneliness | Pancreas Cancer | Cancer Metastatic | Uterine Cancer | Social Isolation

United States
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome

DiGeorge Syndrome | 22q11.2 Deletion Syndrome

United States

Clinical Trials on Relapsed/Refractory Multiple Myeloma

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cameroon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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