Clinical Trials on Renal Impairment

Total 12603 results

University of Vermont
Medical University of South Carolina; University of Washington; University of...

Active, not recruiting

Communication During Hospitalization About Resuscitation Trial (CHART)

End Stage Renal Disease | Severe Life-limiting COPD | Severe Life-limiting Heart Failure | Severe Life-limiting Cirrhosis | Severe Life-limiting Malignancy | Severe Functional Impairment

United States
Merck Sharp & Dohme LLC

Completed

A Study to Assess Pharmacokinetics (PK) of Preladenant in Participants With Chronic Renal Impairment (CRI) (P06512)

Parkinson Disease
Guangdong Raynovent Biotech Co., Ltd

Completed

Pharmacokinetics of Leritrelvir(RAY1216) in Participants With Severe Kidney Disease

Kidney Impairment

China
Lexicon Pharmaceuticals

Completed

Study to Evaluate the Pharmacodynamic and Pharmacokinetic Effects of LX4211 in Subjects With Type 2 Diabetes and Renal Impairment

Type 2 Diabetes Mellitus | Renal Impairment

United States
Guangdong Raynovent Biotech Co., Ltd

Recruiting

Pharmacokinetics of ZSP1273 in Participants With Severe Kidney Disease

Kidney Impairment

China
Gilead Sciences

Completed

Pharmacokinetics of Voxilaprevir in Adults With Normal Renal Function and Severe Renal Impairment

HCV Infection

United States, New Zealand, Germany
Astellas Pharma Inc

Completed

A Study of the Safety and Tolerance of Regadenoson in Subjects With Renal Impairment

Coronary Artery Disease | Kidney Diseases

United States
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Healthy Volunteers | Moderate Hepatic Impairment | Severe Hepatic Impairment

United States
Fondazione Don Carlo Gnocchi Onlus
University of Milano Bicocca

Completed

ABILITY - TelerehABILITation: TechnologY-enhanced Multi-domain at Home Continuum of Care Program

Dementia | Alzheimer Disease | Cognitive Impairments
Celgene

Completed

Study of Pomalidomide to Evaluate the Pharmacokinetics and Safety for Patients With Multiple Myeloma and Impaired Renal Function (POM Renal) (POM Renal)

Multiple Myeloma | Renal Impairment

United States, Canada
Mohammed Ramadan Abdallah
Assiut University

Unknown

Frequency Of Eye Problems In Type 2 Diabetes With Chronic Kidney Disease

Eye Diseases | Renal Impairment | Type2 Diabetes
Oncopeptides AB

Terminated

PK of Melphalan During Treatment With Melflufen and Dexamethasone in Patients With RRMM and Impaired Renal Function (BRIDGE)

Multiple Myeloma | Renal Impairment

Greece, Czechia, Poland
Pfizer
Pfizer

Recruiting

Study of GBT021601 in Participants With Renal Impairment

Renal Impairment

United States
Team Foods Colombia S.A.
Biopolis S.L.

Unknown

Study to Evaluate the Effect of a Vegetal Oil on Cognitive Impairment

Alzheimer Disease | Cognitive Impairments

Spain
H. Lundbeck A/S

Completed

Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects

Heptic Impairment

Germany
Region Skane
Lund University; Berry Lab

Completed

Effect of Nordic Berries on Cognitive Function, Cardiometabolic Risk Markers and Gut Microbiota in Adults With Mild Cognitive Impairment (MINDBERRY)

Memory Impairment | Cognitive Impairment, Mild

Sweden
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Single-Dose Study to Evaluate the PKs of Pretomanid in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function

Renal Impairment | Tuberculosis

United States
Bayer

Recruiting

A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Chronic Kidney Disease | Hepatic Impairment

United States
Merck Sharp & Dohme LLC

Completed

Belzutifan (MK-6482) Hepatic Impairment Study (MK-6482-020)

Moderate Hepatic Impairment

United States
EQRx International, Inc.

Completed

An Open-Label, Single-Dose, Parallel-Group Study of the Pharmacokinetics and Safety of EQ143

Severe Hepatic Impairment

United States
Pfizer

Completed

Evaluate Severe Hepatic Impairment on Dacomitinib PK

Severe Hepatic Impairment

United States
Takeda

Completed

Pharmacokinetics, Safety and Tolerability of Vortioxetine in Normal Hepatic Function or Severe Hepatic Impairment

Severe Hepatic Impairment

United States
Fondazione Don Carlo Gnocchi Onlus
University of Florence; Consorzio di Bioingeneria e Informatica Medica; Gutenberg...

Completed

Cognitive and Physical Home-rehabilitation by Information and Communications Technology. Games for Older Adults Active Life (GOAL) (GOAL)

Cognitive Dysfunction | Mild Cognitive Impairment | Vascular Cognitive Impairment

Italy
Stanford University

Recruiting

CogT pSOPT Intervention Study

Mild Cognitive Impairment | Subjective Cognitive Impairment

United States
University of California, Los Angeles

Completed

18-Month Study of Memory Effects of Curcumin (Curcumin)

Mild Cognitive Impairment (MCI) | Age-associated Cognitive Impairment

United States
Gilead Sciences

Completed

Open-label Safety Study of E/C/F/TAF (Genvoya®) in HIV-1 Positive Patients With Mild to Moderate Renal Impairment

HIV Infections | HIV

United States, Netherlands, Spain, Mexico, France, Thailand, Australia, United Kingdom, Dominican Republic
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Hepatic Impairment (HI)
Bausch Health Americas, Inc.

Terminated

Steady-State Pharmacokinetics of Rifaximin 550 mg Tablets in Healthy and Hepatically Impaired Subjects

Severe Hepatic Impairment

United States
KBP Biosciences
Covance

Completed

Pharmacokinetics of KBP-5074 in Patients With Moderate Hepatic Impairment

Healthy | Moderate Hepatic Impairment

United States
Tibotec BVBA

Completed

A Study of TMC207 in Patients With Moderately Impaired Hepatic Function

Moderate Hepatic Impairment
Agios Pharmaceuticals, Inc.

Completed

A Pharmacokinetic Study of Mitapivat in Participants With Moderate Hepatic Impairment Compared to Matched Healthy Control Participants With Normal Hepatic Function

Moderate Hepatic Impairment

United States
Universidad de Zaragoza

Recruiting

Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities

Mild Cognitive Impairment | Randomized Controlled Trial | Subjective Cognitive Impairment

Spain
Vanderbilt University
Tennessee Department of Education

Recruiting

Providing Access to the Visual Environment

Vision Impairment

United States
University of California, San Francisco
Federal University of Minas Gerais

Completed

Better Memory With Literacy Acquisition Later in Life

Memory Impairment

Brazil
Sunshine Lake Pharma Co., Ltd.

Completed

To Evaluate the Pharmacokinetics and Safety of Yimitasvir Phosphate Capsules in Subjects With Moderate and Severe Liver Function Impairment and in Healthy Subjects

Hepatic Impairment

China
Westat
United States Social Security Administration

Completed

Supported Employment Demonstration (SED)

Mental Impairment

United States
Eisai Inc.
Eisai Limited

Completed

Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment

Attention Impairment

United States, Netherlands, France, Spain, United Kingdom, Germany, Argentina, Canada, Australia, Chile
Loewenstein Hospital

Completed

Differences in Muscle Activity Patterns and Graphical Product Quality in Children With Graphomotor Impairment

Graphomotor Impairment

Israel
Porter Adventist Hospital

Terminated

Donepezil Memory Preservation Post ECT

Memory Impairment

United States
Janssen Research & Development, LLC

Withdrawn

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Odalasvir and AL-335 Alone and in Combination With Simeprevir in Participants With Moderately Impaired Hepatic Function

Hepatic Impairment
Stanford University
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Age-related Longitudinal Changes in Aviator Performance

Memory Impairment

United States
US Department of Veterans Affairs

Completed

Restricted Useful Field View as a Risk Factor in Older Adults

Vision Impairment

United States
Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
Jazz Pharmaceuticals

Completed

Assessment of the Single Dose Pharmacokinetics and Tolerability of Sativex in Patients With Impaired Hepatic Function and Healthy Patients

Hepatic Impairment

United States
Yale University

Completed

The Effects of Minocycline in Humans

Memory Impairment

United States
Seagen Inc.

Completed

A Safety Study of Tucatinib in Healthy and Hepatically-Impaired Subjects

Hepatic Impairment

United States
University of Manitoba

Unknown

Examining the Effect of a Simple Memory Tool

Memory Impairment

Canada
University of Manitoba

Unknown

Memory Intervention for Older Adults - (Social) (Social)

Memory Impairment
VA Office of Research and Development

Not yet recruiting

User Evaluation of Advanced Personalized Modular Pressure Relief Seating Cushion Systems (Squishycushion)

Mobility Impairment

United States
Shire

Completed

Pharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared to Healthy Participants

Hepatic Impairment

United States

Clinical Trials on Renal Impairment

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Turkmenistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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