Clinical Trials on Resistant Arterial Hypertension

Total 35947 results

United Therapeutics

Completed

Safety and Tolerability of Rapid Dose Titration of Subcutaneous Remodulin® Therapy in PAH Subjects (RAPID) (RAPID)

Pulmonary Arterial Hypertension
Amsterdam UMC, location VUmc

Unknown

Goal Oriented Strategy to Preserve Ejection Fraction Trial (GOSPEL)

Pulmonary Arterial Hypertension

Netherlands
University of Arizona
United Therapeutics

Completed

Study Of Right Ventricular Performance In PAH Patients Treated With Rapid Dose Treprostinil (Remodulin) (ISS)

Pulmonary Arterial Hypertension

United States
United Therapeutics

Completed

Remodulin® to Oral Treprostinil Transition

Pulmonary Arterial Hypertension

United States
Actelion

Terminated

Ventavis® Registry Protocol (RESPIRE)

Pulmonary Arterial Hypertension

United States
Nantes University Hospital

Withdrawn

Evaluation of Metformin Activity in Addition to Conventional Treatment of Grade II or III Pulmonary Arterial Hypertension (PAH) (MetHTAP)

Pulmonary Arterial Hypertension

France
Mayo Clinic

Completed

Modulating Effects of Lisinopril on Sildenafil Activity in Pulmonary Arterial Hypertension(PAH)( MELISSA) (MELISSA)

Pulmonary Arterial Hypertension

United States
Rabin Medical Center

Unknown

Rehabilitation for Patients With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Israel
Bial - Portela C S.A.

Terminated

Effect of Age-gender on the Pharmacokinetic and Pharmacodynamic Profiles of BIA 5 1058

Pulmonary Arterial Hypertension
Bial - Portela C S.A.

Completed

Absorption, Distribution, Metabolism and Excretion of BIA 5-1058 (ADME)

Pulmonary Arterial Hypertension

Netherlands
Pfizer's Upjohn has merged with Mylan to form Viatris...

No longer available

An Open Label Access Study For Subjects Who Completed A1481156

Pulmonary Arterial Hypertension

India
Hanmi Pharmaceutical Company Limited

Completed

To Compare the Pharmacokinetics of Traclear 62.5 mg Tablets and HGP1206 125mg 1 Tablet in Healthy Male Volunteers

Pulmonary Arterial Hypertension

Korea, Republic of
Karos Pharmaceuticals

Completed

Single and Multiple Ascending Doses Clinical Pharmacology Study With KAR5585

Pulmonary Arterial Hypertension

United States
United Therapeutics

Completed

Tyvaso Dosing and Titration Evaluation: TyTRATE Registry

Pulmonary Arterial Hypertension

United States, Puerto Rico
United Therapeutics

Completed

Comparative Bioavailability of Treprostinil Diethanolamine Manufactured by Two Independent Facilities

Pulmonary Arterial Hypertension

United States
United Therapeutics

Completed

Pharmacokinetic Linearity and Comparative Bioavailability of Treprostinil Diethanolamine

Pulmonary Arterial Hypertension

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Pivotal Bioequivalence Study Between The Sildenafil Powder For Oral Suspension (10 Mg/Ml) And The Sildenafil 10 Mg Immediate Release (IR) Tablet Relative To The Revatio 20 Mg IR Tablet In Healthy Volunteers Under Fasting Conditions

Pulmonary Arterial Hypertention

Belgium
China National Center for Cardiovascular Diseases

Recruiting

Combined Use of Radiofrequency-ablation and Balloon-septostomy in the Creation of a Stable Inter-atrial Communication (CURB)

Pulmonary Arterial Hypertension

China
Bayer
Xcenda, LLC

Active, not recruiting

A Study to Learn About How Well Riociguat Works, How Safe it is and How it is Used Under Real World Conditions in Patients in the United States Who Are Receiving Riociguat for High Blood Pressure in the Arteries That Carry Blood From the Heart to the Lungs (Pulmonary Arterial Hypertension, PAH) (ROAR)

Pulmonary Arterial Hypertension

United States, Puerto Rico
United Therapeutics

Active, not recruiting

Evaluate Real-World Use of Next Generation Infusion Pumps to Administer Remodulin (EVOLVE)

Pulmonary Arterial Hypertension

United States
Merck Sharp & Dohme LLC

Completed

A Study of Single Doses of MK -5475 on Pulmonary Vascular Resistance (MK-5475-002)

Pulmonary Arterial Hypertension

Moldova, Republic of
PhaseBio Pharmaceuticals Inc.

Terminated

Phase 2 Study to Assess Safety, Tolerability and Efficacy of Once Weekly SC Pemziviptadil (PB1046) in Subjects With Symptomatic PAH (VIP)

Pulmonary Arterial Hypertension

United States
University of Pittsburgh

Withdrawn

miRNA and Myokines in Patients With PAH

Pulmonary Arterial Hypertension

United States
Bayer

Completed

Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy (REPLACE)

Pulmonary Arterial Hypertension

Belgium, France, Spain, Portugal, Turkey, United States, Germany, Korea, Republic of, Mexico, Austria, Canada, Denmark, Poland, Italy, Greece, Taiwan, Czechia, Netherlands, Japan, Brazil, United Kingdom
PhaseBio Pharmaceuticals Inc.

Completed

A Study to Assess the Safety, Tolerability, and Hemodynamic Response of PB1046 in Subjects With PAH

Pulmonary Arterial Hypertension

United States
National Health Service, United Kingdom

Completed

The Effect of Adding Exercise Training to Optimal Therapy in PAH

Pulmonary Arterial Hypertension

United Kingdom
Medical University of Bialystok

Completed

PET/MRI in PAH Patients

Pulmonary Arterial Hypertension
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Right Ventricular Pulmonary Vascular Interaction in Pulmonary Hypertension

Pulmonary Arterial Hypertension (PAH)
United Therapeutics

Terminated

Safety Study of PLX-PAD Cells to Treat Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

Australia
Actelion

Completed

Combination Therapy in Pulmonary Arterial Hypertension (COMPASS 3)

Pulmonary Arterial Hypertension

United States
Northwell Health

Completed

Biomarkers in the Diagnosis and Assessment of Pulmonary Arterial Hypertension (PAH) (Biomarkers)

Pulmonary Arterial Hypertension

United States
University Medical Center Rostock
Techniker Krankenkasse; AOK Nordwest; Philips GmbH Market DACH; AMEDON GmbH; Lohfert... and other collaborators

Unknown

Investigation of a Novel Integrated Care Concept (NICC) for Patients Suffering From Chronic Cardiovascular Disease (CardioCare MV)

Heart Failure | Atrial Fibrillation | Treatment Resistant Hypertension

Germany
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Chronic Thrombo-embolic Pulmonary Hypertension: Classification and Long Term Outcome

Idiopathic Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

United Kingdom
Viatris Pharmaceuticals Japan Inc

Completed

Revatio Special Investigation for Long-term Use in Pediatric Patients

Pulmonary Arterial Hypertension

Japan
Actelion

Completed

A Registry for Patients Taking Uptravi (SPHERE)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Gmax Biopharm Australia Pty Ltd.
Metaclinical; Syneos Heath

Completed

A Study to Investigate Safe and Tolerable Dose of GMA301 Injection in Healthy Volunteers

Pulmonary Arterial Hypertension

Australia
Bial - Portela C S.A.

Completed

Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Sildenafil

Pulmonary Arterial Hypertension

Germany
Bial - Portela C S.A.

Completed

Effect of BIA 5-1058 400 mg on Warfarin Pharmacokinetics

Pulmonary Arterial Hypertension

Germany
Roham T. Zamanian
Duke University; SRI International

Completed

Subcutaneous Elafin in Healthy Subjects

Pulmonary Arterial Hypertension

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

No longer available

Local Open-Label Access Study For Patients Who Completed A1481244 Study In Brazil

Pulmonary Arterial Hypertension

Brazil
Pfizer's Upjohn has merged with Mylan to form Viatris...

No longer available

Sildenafil Therapy For Subjects Who Derive Clinical Benefit From Continued Treatment With Sildenafil

Pulmonary Arterial Hypertension

Russian Federation
Actelion

Completed

OPsumit USers Registry (OPUS)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Actelion

Completed

Retrospective Chart Review of First-time Opsumit® (Macitentan) Users in the United States (OrPHeUS)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Regina Steringer-Mascherbauer

Unknown

3D Echo Evaluation of the Ventricles in Sclero Associated Severe PAH (EVA3D)

Pulmonary Arterial Hypertension

Austria
Pfizer

Withdrawn

Drug Interaction Between Ritonavir And Sitaxsentan

Pulmonary Arterial Hypertension
Pfizer

Withdrawn

Effect Of Rifampin On Pharmacokinetics Of Sitaxsentan

Pulmonary Arterial Hypertension
Aurora Health Care

Completed

Nitric Oxide, GeNO Nitrosyl Delivery System

Pulmonary Arterial Hypertension

United States
George Washington University

Completed

Estimation of Pulmonary Vascular Resistance by Contrast Echocardiography

Pulmonary Arterial Hypertension
Echosense Ltd.

Terminated

Measuring Blood Pressure in the Lung Circulation With Sonar Technology (Echo-Doppler)

Pulmonary Arterial Hypertension

Israel
Berlin-Chemie Menarini

Completed

Effects of Nebivolol on Subclinical Left Ventricular dySfunction: A Comparative Study Against Metoprolol (ENESYS)

Primary Arterial Hypertension

Romania

Clinical Trials on Resistant Arterial Hypertension

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Equatorial Guinea

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations