Clinical Trials on Resistant Major Depression in Italy

Total 342 results

Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY MDD)

Major Depressive Disorder | Treatment Resistant Depression

Austria, Germany, Italy, Spain, United Kingdom
AstraZeneca

Completed

Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients (RUBY)

Major Depressive Disorder | Treatment Resistant Depression

Bulgaria, Italy, United Kingdom, Germany, Hungary, Romania, Austria, Belgium, Denmark, Portugal, Slovakia, Australia, Spain
ITAB - Institute for Advanced Biomedical Technologies

Recruiting

Translational Biomarkers in Accelerated Neuromodulation for Treatment-resistant Depression (ReModula)

Treatment Resistant Depression

Italy
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; Ministry of Health...

Recruiting

Improving Health Care in Major Depressive Disorder (DepType)

Major Depressive Disorder

Italy
Azienda Socio Sanitaria Territoriale degli Spedali...
IRCCS Istituto Centro San Giovanni di Dio- Fatebenefratelli

Recruiting

Clinical Validation of a Combinatorial Pharmacogenomic Approach in Major Depressive Disorder (PANDORA)

Major Depressive Disorder

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
University of Trieste; IRCCS Fondazione Stella Maris; CNR Institute of Neuroscience...

Recruiting

Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy) (GAPsy)

Healthy | Depression, Anxiety

Italy
Institute of Neuroscience, Florence, Italy

Completed

Bilateral Versus Monolateral Repetitive Transcranial Stimulation in Depression

Major Depression

Italy
Fidia Farmaceutici s.p.a.

Recruiting

Safety of Liposom With Citalopram in Elderly Patients With Major Depressive Disorder

Major Depressive Disorder

Italy
Istituto Auxologico Italiano

Recruiting

Potential Predictive Biological Markers of Major Depression Response to Citalopram Therapy in Anorexia Nervosa. (ANCITA)

Anorexia Nervosa

Italy
University of Campania "Luigi Vanvitelli"
University of Pisa; University of Bologna; University of Roma La Sapienza; Universita... and other collaborators

Recruiting

Psychoeducational Intervention for Families With a Member Affected by Major Depression

Depressive Disorder, Major

Italy
H. Lundbeck A/S

Completed

Study With Vortioxetine on Emotional Functioning in Patients With Depression (COMPLETE)

Major Depressive Disorder

France, Italy, Lithuania, Spain
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN) (RONIN)

Major Depressive Disorder | Bipolar Affective Disorder, Currently Depressed, Moderate

Italy
Aziende Chimiche Riunite Angelini Francesco S.p.A

Completed

Trazodone Once a Day in Major Depression Disorder

Major Depressive Disorder

Austria, Czech Republic, Italy, Romania, Slovakia, Spain
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

Finland, Germany, Korea, Republic of, United States, Taiwan, Estonia, India, Italy, Mexico
Eli Lilly and Company

Completed

A Study in Prevention of Re-emergence of Depression Symptoms

Major Depressive Disorder

United States, Germany, Italy, Turkey, Russian Federation, Korea, Republic of, Greece, France, Croatia, Romania, Spain, Argentina, Puerto Rico, Belgium, Mexico, Slovakia
AstraZeneca

Completed

A Non Interventional Study to Investigating the Ratio of Mis-diagnosed Bipolar Symptoms in Patient With Major Depressive Disorder (MDD) (Improve)

Major Depressive Disorder | MDD

Italy
H. Lundbeck A/S

Completed

Real-life Effectiveness of Vortioxetine in Depression (RELIEVE)

Major Depressive Disorder

United States, Canada, France, Italy
Azienda Ospedaliero-Universitaria Careggi

Recruiting

Sumor as Adjuvant Therapy in Treatment-resistant Major Depression (SUSCA)

Major Depressive Disorder

Italy
Eli Lilly and Company

Completed

Early Versus Delayed Switch in Medication in Patients With Major Depressive Disorder

Major Depressive Disorder

Denmark, France, Greece, Hungary, Italy, Netherlands, Romania, Slovenia, Spain, Sweden, Turkey
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Completed

Boosting Psychotherapy Effects by Means of Transcranial Direct Current Stimulation (PSYCHOBOOST)

Major Depressive Disorder

Italy
IRCCS San Raffaele

Recruiting

Inflammatory Control of Antidepressant Efficacy: a Pharmaco-epigenetic Approach

Mood Disorders | Major Depressive Disorder

Italy
Azienda Ospedaliera Universitaria Integrata Verona
University of Catania

Completed

Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment (VESPA)

Major Depressive Disorder

Italy
Janssen Research & Development, LLC

Active, not recruiting

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

Depressive Disorder, Major

United States, Spain, Italy, United Kingdom
H. Lundbeck A/S

Completed

Continuation With Vortioxetine in Child and Adolescent Patients With Major Depressive Disorder (MDD) From 7 to 17 Years of Age

Depressive Disorder, Major

Spain, Hungary, Russian Federation, Bulgaria, Estonia, France, Germany, Italy, Latvia, Poland, Serbia, South Africa, United Kingdom
H. Lundbeck A/S
ICON plc

Completed

Vortioxetine in Patients With Depression and Early Dementia (MEMORY)

Dementia | Major Depressive Disorder

Korea, Republic of, Spain, Poland, Estonia, France, Italy
H. Lundbeck A/S

Terminated

Long-term, Open-label, Flexible-dose, Extension Study of Vortioxetine in Child and Adolescent Participants With Major Depressive Disorder (MDD) From 7 to 18 Years of Age

Depressive Disorder, Major

United States, Korea, Republic of, Hungary, Poland, Spain, Serbia, Estonia, Bulgaria, Latvia, Russian Federation, Ukraine, Canada, Colombia, France, Germany, Israel, Italy, Mexico, South Africa, United Kingdom
H. Lundbeck A/S
Takeda

Completed

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD)

Depressive Disorder, Major

United States, Bulgaria, Canada, Colombia, Estonia, France, Germany, Hungary, Italy, Korea, Republic of, Latvia, Mexico, Poland, Russian Federation, Serbia, South Africa, Spain, Ukraine, United Kingdom
H. Lundbeck A/S
Takeda

Completed

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD)

Depressive Disorder, Major

Korea, Republic of, United States, Hungary, Poland, Spain, Serbia, Estonia, Bulgaria, Mexico, Russian Federation, Ukraine, Canada, Colombia, France, Germany, Israel, Italy, Latvia, South Africa
GlaxoSmithKline

Completed

Study Of The Effects Of A New Antidepressant Therapy In Patients With Major Depressive Disorder (MDD)

Depressive Disorder, Major

Belgium, Peru, Argentina, Chile, Costa Rica, Slovakia, Italy, Germany, Poland, Spain, Sweden
Janssen Research & Development, LLC

Recruiting

A Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD) (VENTURA-LT)

Depressive Disorder, Major

United States, Korea, Republic of, Taiwan, Slovakia, Spain, Bulgaria, Poland, Belgium, Argentina, Czechia, Hungary, South Africa, Sweden, Italy, France, Australia, China, Brazil, Portugal
IRCCS San Raffaele

Recruiting

Immune Activation, Neural Plasticity and Depression

Mood Disorders | Sleep Deprivation | Major Depressive Disorder

Italy
Janssen Research & Development, LLC

Completed

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Depressive Disorder, Major

United States, France, Italy, Spain, Hungary, Belgium, Brazil, Bulgaria, Poland
Eli Lilly and Company
Boehringer Ingelheim

Completed

Duloxetine Versus Placebo in the Prevention of Recurrence of Major Depressive Disorder

Depressive Disorder, Major

United States, France, Germany, Italy, Russian Federation, Sweden
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder

Migraine | Major Depressive Disorder

United States, Czechia, Finland, Israel, Italy, Russian Federation, Spain, Ukraine, France, Germany, Greece, Poland, United Kingdom
Eli Lilly and Company
Boehringer Ingelheim

Completed

A Study Evaluating Duloxetine in Patients Hospitalized for Severe Depression

Major Depressive Disorder

France, Italy, Russian Federation, South Africa
Janssen Research & Development, LLC

Recruiting

A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI) (VENTURA-RWE)

Depressive Disorder, Major

United States, Korea, Republic of, Spain, Argentina, United Kingdom, Sweden, Italy, Germany, France, Canada, Brazil
University of Milano Bicocca
Università degli Studi di Trento; National Research Council

Enrolling by invitation

In Vitro Modeling of Drug-resistant Psychiatric Disorders Using Induced Pluripotent Cells

Depressive Disorder, Treatment-Resistant

Italy
Janssen Research & Development, LLC

Recruiting

A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy (VENTURA-1)

Anhedonia | Depressive Disorder, Major

United States, Spain, Bulgaria, Italy, Poland, Belgium, Argentina, Czechia, Hungary, Sweden, Brazil, Australia, Portugal
Catholic University of the Sacred Heart
University Hospital, Geneva; Universiteit Antwerpen; Clinical Centre of Serbia; Canisius-Wilhelmina Hospital and other collaborators

Unknown

SATURN 04 Nosocomial Acquisition Study (SATURN)

Infection Due to ESBL Bacteria | Bacterial Resistance | Infection Resistant to Multiple Drugs | Staph Aureus Methicillin Resistant Colonization

Italy, Romania, Serbia
IRCCS San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Recruiting

Development of a Software Tool, Using Artificial Intelligence, That Integrates Clinical, Biological, Genetic and Imaging Data to Predict Diagnosis and Outcome of Depressed Patients in Order to Enhance Prognosis and Limiting Healthcare Costs.

Bipolar Disorder | Unipolar Depression

Italy
Ospedale Amedeo di Savoia

Unknown

Italian Network for the Improvement of Compliance in Depression

Depression

Italy
Universita di Verona

Unknown

Lithium and Standard Therapy in Resistant Depression (LAST)

Depression

Italy
Azienda Ospedaliera Universitaria Policlinico Paolo...
University of Palermo; Centro Studi Psicoterapia Neo-Funzionale

Completed

The Evaluation of the Efficacy of a Fasting Mimicking Diet Added to Functional Therapy for Depression

Depression

Italy
IRCCS San Raffaele
Ministry of Health, Italy

Recruiting

Immune/Inflammatory Biomarkers in Postpartum Depression (PPDINFLAME)

Depression, Postpartum

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

DRACULA1 Partum Depression: an Integrated Molecular-pharmaco-imaging Study")

Post-partum Depression

Italy
University of Catania

Completed

Silybin Supplementation During HCV Therapy With Pegylated Interferon-α2b Plus Ribavirin Reduces Depression and Increases Work Ability

Depression | Work Ability

Italy
IRCCS Centro San Giovanni di Dio Fatebenefratelli

Unknown

Telemedicine for Depression in Primary Care

Depression

Italy
Nutrilinea srl
Hippocrates Research

Completed

EVALUATION OF EFFICACY OF SAMEUP IN SUBJECTS WITH DEPRESSION SYMPTOMS: A RANDOMIZED STUDY (SAMEUP)

Depressive Symptoms

Italy
Federico II University

Recruiting

Exercise in Pregnancy and Risk of Postpartum Depression

Depression | Pregnancy Related

Italy
University of Pittsburgh
National Institute of Mental Health (NIMH)

Completed

Treatment of Depression in Adults

Depression

United States, Italy

Clinical Trials on Resistant Major Depression in Italy

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Pakistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations