Clinical Trials on Respiratory Syncytial Virus (RSV) Infection in South Africa

Total 2083 results

International Partnership for Microbicides, Inc.

Completed

An Expanded Safety Study of Dapivirine Gel 4789 in Africa

HIV Infections | Acquired Immunodeficiency Syndrome | Healthy

South Africa
Janssen Vaccines & Prevention B.V.

Completed

A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older (EVERGREEN)

Respiratory Syncytial Viruses | Lower Respiratory Tract Disease

United States, Taiwan, Thailand, Canada, Poland, United Kingdom, Brazil, Chile, New Zealand, Estonia, Finland, South Africa, Australia, China
Evangelismos Hospital

Completed

Implementing a Rehabilitation Program in Patients Recovering From Covid-19 Infection

Rehabilitation

Greece
PATH
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Completed

Phase II Safety and Acceptability of an Investigational Injectable Product, TMC278LA, for Pre-Exposure Prophylaxis (TMC278LA)

Human Immunodeficiency Virus (HIV)

United States, South Africa, Zimbabwe
Brno University Hospital
Masaryk University

Recruiting

High Flow Oxygen in Preoxygenation During Rapid Sequence Induction in Infants and Small Children (PRSIHFO)

Preoxygenation | Rapid Sequence Induction (RSI)

Czechia
Murdoch Childrens Research Institute
Bill and Melinda Gates Foundation; Royal Children's Hospital

Completed

BCG Vaccination to Protect Healthcare Workers Against COVID-19 (BRACE)

COVID-19 | Corona Virus Infection | Coronavirus Disease 2019 (COVID-19) | Respiratory Illness

Australia, Brazil, Netherlands, Spain, United Kingdom
Sanofi

Completed

Study of Inactivated, Split-Virion Influenza Vaccine Compared With Standard Fluzone Vaccine in Elderly Subjects

Influenza | Orthomyxoviridae Infection | Myxovirus Infection

United States
University of Sydney

Completed

Herpes Zoster Vaccine for Bone Marrow Transplant Donors (VZV-Zostavax)

Herpes Zoster

Australia
Washington University School of Medicine
COVID -19 Therapeutics Accelerator

Completed

CROWN CORONATION: COVID-19 Research Outcomes Worldwide Network for CORONAvirus prevenTION (CROWN CORONA)

COVID 19

United States, South Africa, Ghana, United Kingdom, Zambia
Vaxine Pty Ltd
Australian Respiratory and Sleep Medicine Institute; Flinders University

Completed

A Phase 1 Study to Evaluate the Immunogenicity and Safety of a Pandemic Avian Influenza Vaccine in Adults (FLU003)

Influenza

Australia
Kimberly-Clark Corporation

Completed

Nasal Swab Study to Explore the Nasal Microbia

Common Cold

United States
Bayer

Completed

Acetylsalicylic Acid Combined With Pseudoephedrine in Common Cold

Common Cold

United Kingdom
AstraZeneca

Active, not recruiting

A Randomized Trial Evaluating a mRNA-VLP Vaccine's Immunogenicity and Safety for COVID-19 (ARTEMIS-C)

COVID-19 | SARS-CoV-2 Infection

United States
Seqirus

Completed

A Clinical Trial of CSL's 2009 H1N1 Influenza Vaccine (CSL425) in Healthy Adults

Influenza Caused by the Novel Influenza A (H1N1) Virus

Australia
Medical University of South Carolina
The Skin Center Dermatology Group

Completed

Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca

Verruca Vulgaris | Molluscum Contagiosum Skin Infection

United States
Aeras
Statens Serum Institut

Completed

A Phase I Study of Safety & Immunogenicity of AERAS-456 in HIV-Neg. Adults Treated for Drug-susceptible Pulmonary TB (C-037-456)

Tuberculosis

South Africa
Norwegian Institute of Public Health
University of Stellenbosch; European and Developing Countries Clinical Trials... and other collaborators

Recruiting

Evaluation of a Rapid Point-of-Care Serological Triage Test for Active TB (SeroSelectTB)

Tuberculosis, Pulmonary

South Africa, Tanzania, Ethiopia
University of Stellenbosch
Amsterdam Institute for Global Health and Development; Makerere University; University...

Recruiting

Cough Audio Classification as a TB Triage Test (CAGE-TB)

Tuberculosis

South Africa, Uganda
Medicago

Completed

Immunogenicity, Safety, and Tolerability of a Plant-Derived Quadrivalent VLP Influenza Vaccine in Elderly Adults

RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases

United States, Canada
GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK Biologicals' Herpes Zoster Vaccine 1437173A in Healthy Ethnic Japanese Adults

Herpes Zoster

Australia
Osivax
Novotech (Australia) Pty Limited; Harmony Clinical Research; Northern Beaches...

Completed

Immunogenicity and Safety of the Concomitant Administration of OVX836 and Quadrivalent Influenza Vaccine in Healthy Volunteers.

Influenza

Australia
Quidel Corporation

Completed

QuickVue Influenza A+B Clinical Field Trial

Influenza

Australia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Effectiveness of Lopinavir/Ritonavir in Individuals Who Have Failed Prior HIV Therapy

HIV Infections

Malawi, South Africa, India, Tanzania, Thailand
Foundation for Innovative New Diagnostics, Switzerland

Completed

Accuracy and Feasibility of Xpert Ultra

Tuberculosis, Pulmonary

Belarus, Georgia, India, South Africa
Leidos Life Sciences
United States Department of Defense

Terminated

Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients (Addendum 2)

COVID-19 | Covid19 | Coronavirus Disease 2019 | SARS-CoV2 Infection | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Pandemic | COVID-19 Virus Infection | COVID-19 Virus Disease | 2019 Novel Coronavirus Disease | 2019 Novel Coronavirus Infection | 2019-nCoV Disease | 2019-nCoV Infection

United States
Crucell Holland BV

Completed

Evaluation of Viral Shedding Patterns and Clinical Outcomes of Influenza Patients

Influenza

United States, Australia, Canada
Johns Hopkins University
United States Agency for International Development (USAID)

Not yet recruiting

Shortened Regimen for Drug-susceptible TB in Children (SMILE-TB)

Tuberculosis | Tuberculosis, Pulmonary | Mycobacterium Tuberculosis | Tuberculosis, Lymph Node

Uganda, South Africa, Mozambique, Indonesia, Zambia
General and Maternity Hospital of Athens Elena...

Unknown

Maternal Psychological Implications of Covid-19 Pandemic and Possible Effect on Anaesthetic Management.

Covid-19 | Anesthesia | Maternal Psychological Distress

Greece
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Active, not recruiting

Mechanisms of Cardiac Dysfunction in HIV and the Effect of Statins: A Cardiac MRI Study

HIV Infections

United States, South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety of and Adherence to a Vaginal Matrix Ring Containing Dapivirine and Oral Emtricitabine/Tenofovir Disoproxil Fumarate in an Adolescent and Young Adult Female Population

HIV Infections

South Africa, Uganda, Zimbabwe
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs

HIV Infections

South Africa, Uganda, Malawi, Zimbabwe
Athens Medical Society
Elpen Pharmaceutical Co. Inc.; OBCTCD24 Ltd

Recruiting

Safety and Efficacy of Exosomes Overexpressing CD24 in Two Doses for Patients With Moderate or Severe COVID-19

Covid19

Greece
Global Alliance for TB Drug Development

Completed

Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)

Pulmonary Tuberculosis

Tanzania, South Africa
AstraZeneca

Completed

Phase II/III Study of AZD2816, for the Prevention of COVID-19 in Adults (AZD2816)

COVID-19 | SARS-CoV-2

United Kingdom, Brazil, South Africa, Poland
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1018 Pandemic Influenza Candidate Vaccines in Healthy Adults

Influenza

United States
Autoimmune Technologies, LLC

Completed

Safety, Tolerability, and PK of Escalating Doses of Flufirvitide-3 Dry Powder for Inhalation in Healthy Subjects

Influenza

United States
Probiomics Ltd

Unknown

Evaluation of the Safety and Effectiveness of a Probiotic Bacterium to Boost the Immune Response to Influenza Vaccines

Influenza

Australia
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to Two HIV Vaccines: SAAVI DNA-C2 Boosted With SAAVIMVA-C, in HIV-Negative Adults

HIV Infections

United States, South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's Sarcoma (REACT-KS)

Kaposi's Sarcoma | HIV-1 Infection

Peru, Kenya, Malawi, Brazil, South Africa, Uganda
Emmanouil D. Zacharakis

Recruiting

Levels of Physical Activity After SARS-CoV-2 Infection in Pre-illness Vaccinated and Unvaccinated Greek Adults.

COVID-19 (Coronavirus Disease 2019)

Greece
Bill & Melinda Gates Medical Research Institute
Wellcome Trust

Completed

Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine M72/AS01E in Participants With Well-controlled HIV (MESA-TB)

Human Immunodeficiency Virus

South Africa
National Institute of Health Research and Development...
Eijkman Institute for Molecular Biology; Indonesian Red Cross

Recruiting

Convalescent Plasma as Adjunct Therapy for COVID-19 (PlaSenTer)

COVID-19

Indonesia
ViiV Healthcare
GlaxoSmithKline

Completed

Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection

HIV Infections | Infection, Human Immunodeficiency Virus

Mexico, Peru, Thailand, South Africa, Russian Federation, Argentina, Brazil
Osivax
Novotech (Australia) Pty Limited; Mater Misericordiae Limited

Completed

Immunogenicity and Safety of the Concomitant Administration of OVX836 Influenza Vaccine, Quadrivalent Inactivated Influenza Vaccines and Placebo in Healthy Subjects.

Influenza

Australia
GlaxoSmithKline

Completed

Study to Evaluate the Immunogenicity and Safety of an Investigational Pandemic Influenza Vaccine in Children

Influenza

Australia, Singapore
National Institute of Allergy and Infectious Diseases...
Gilead Sciences

Completed

Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum

HIV Infections

Malawi, Zimbabwe, South Africa, Uganda
Vaxine Pty Ltd
Cinnagen; Australian Respiratory and Sleep Medicine Institute Ltd

Active, not recruiting

Booster Study of SpikoGen COVID-19 Vaccine

COVID-19

Australia
Hasanuddin University
Ministry of Agriculture, Republic of Indonesia

Completed

Eucalyptus Oil as Adjuvant Therapy for Coronavirus Disease 19 (COVID-19)

COVID-19

Indonesia
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating Strategies to Reduce Mother-to-Child Transmission of HIV Infection in Resource-Limited Countries (PROMISE)

HIV Infections

Malawi, South Africa, Tanzania, Zimbabwe, India, Uganda, Zambia
Kirby Institute
National Health and Medical Research Council, Australia

Withdrawn

A Prospective Study to Examine the Effectiveness and Safety of Neuraminidase Inhibitors in Volunteers Who Receive Long-term Prophylaxis Against Pandemic Influenza: PIPET B (PIPET B)

Pandemic Influenza

Australia

Clinical Trials on Respiratory Syncytial Virus (RSV) Infection in South Africa

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