Clinical Trials on Retinal Degeneration in United Kingdom

Total 6598 results

Royal Liverpool University Hospital

Unknown

Macular Function During Anti-VEGF Treatment (MAFAT)

Age Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust

Completed

Optimising Visual Acuity Measurement in Macular Degeneration (OPTIMISE)

Age Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust

Completed

Defining Disease Activity in Neovascular AMD With Optical Coherence Tomography Angiography (DANA)

Neovascular Age-related Macular Degeneration

United Kingdom
OKKO Health

Recruiting

OKKO Health Hyperacuity, Contrast and Colour Game Validation in Age-related Macular Degeneration

Age-Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
King's College London; Cardiff University; University College, London; Newcastle... and other collaborators

Recruiting

Quality-Assured Follow-up of Quiescent Neovascular Age -Related maculaR dEgeneration by Non-medical Practitioners (FENETRE)

AMD

United Kingdom
OKKO Health
Nottingham University Hospitals NHS Trust; Oxford University Hospitals NHS... and other collaborators

Enrolling by invitation

Patient-centred Smartphone AI for Protecting Vision in Macular Disease

Age-Related Macular Degeneration

United Kingdom
Second Sight Medical Products

Completed

Argus II Retinal Prosthesis System Dry AMD Feasibility Study Protocol

Age Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust

Completed

VITAL - Individualising Therapy for Neovascular AMD With Aflibercept (VITAL)

Age Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
University College, London

Recruiting

A Study Of Implantation Of Retinal Pigment Epithelium In Subjects With Acute Wet Age Related Macular Degeneration

Age Related Macular Degeneration

United Kingdom
Queen's University, Belfast

Completed

Development of Core Outcomes for Age-related Macular Degeneration (AMD) Interventions- Caregivers' Perspective

Age Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
British Eye Research Foundation, operating as Fight for Sight

Completed

EFFECT:Eccentric Fixation From Enhanced Clinical Training (EFFECT)

Age Related Macular Degeneration (ARMD)

United Kingdom
Aston University
The Dunhill Medical Trust

Completed

Colour Contrast Sensitivity for the Early Detection of Wet Age-related Macular Degereration (CEDAR) (CEDAR)

Age Related Macular Degeneration

United Kingdom
King's College Hospital NHS Trust
King's College London

Completed

A Pharmacokinetic Study: Ranibizumab, Aflibercept and the Effect of Vitrectomy. (VITCLEAR)

Age Related Macular Degeneration

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust

Not yet recruiting

Retinal Pigment Epithelium Safety Study For Patients In B4711001

Age Related Macular Degeneration

United Kingdom
Maastricht University Medical Center
Cognis Deutschland GmbH & Co. KG

Completed

The Influence of Lutein Supplements on Age-related Macular Degeneration

Age-Related Macular Degeneration

Netherlands, United Kingdom
Bayer
RTI Health Solutions

Completed

Evaluation of Physician and Patient Knowledge of Safety and Safe Use Information for Aflibercept

Macular Degeneration

France, Germany, Spain, Italy, United Kingdom
University of Manchester

Completed

Development of a Device to Measure Dark Adaptation

Age-Related Macular Degeneration | Macular Degeneration

United Kingdom
Newtricious R&D BV
Sprim Advanced Life Sciences

Completed

Intervention Trial in Early Age-related Macular Degeneration (I-TEAM)

Age-related Macular Degeneration (AMD)

United States, Germany, Netherlands, United Kingdom
Brighton and Sussex University Hospitals NHS Trust

Completed

Ocular Coherence Tomography During Cataract Assessment

Age Related Macular Degeneration | Cataract Senile | Epiretinal Membrane | Vitreomacular Traction | Macula Hole

United Kingdom
Azienda Ospedaliera Universitaria Mater Domini,...

Recruiting

Photobiomodulation in Dry Age Related Macular Degeneration (DRUSEN)

Age-Related Macular Degeneration

France, Italy, Turkey, United Kingdom
Bayer

Completed

Study to Assess the Effectiveness of Existing Anti vascUlar Endothelial Growth Factor (Anti VEGF) in Patients With Wet Age-related Macular Degeneration (wAMD) (AURA) (AURA)

Ophthalmology, Macular Degeneration

Japan, France, Germany, Australia, Italy, United Kingdom, Venezuela, Ireland, Netherlands, Canada
Oraya Therapeutics, Inc.

Unknown

An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (ENDEAVOUR)

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Retinal Diseases | Wet Macular Degeneration

United Kingdom
University of Illinois at Chicago

Completed

Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration

Retinal Degenerations

United States
King's College Hospital NHS Trust

Completed

Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMD (TAPAS)

Exudative Macular Degeneration | Retinal Hemorrhage

United Kingdom
Moorfields Eye Hospital NHS Foundation Trust
Brighton and Sussex University Hospitals NHS Trust; University Hospitals Bristol... and other collaborators

Completed

Multicentre Randomised Clinical Trial Comparing Fixed vs Pro re Nata (PRN) Dosing of 700 μg Dexamethasone (OZDRY)

Diabetic Macular Edema

United Kingdom
Oraya Therapeutics, Inc.

Withdrawn

Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV)

Macular Degeneration | Age-related Macular Degeneration | AMD | Wet AMD | Wet Age-related Macular Degeneration

United Kingdom, Italy
Hoffmann-La Roche

Completed

A Study of RO6867461 Administered in Single- and Multiple-Ascending Doses in Patients With Wet Age-Related Macular Degeneration

Macular Degeneration

United States, United Kingdom
NeoVista

Unknown

A Study of the NeoVista Ophthalmic System for the Treatment of Subfoveal CNV Associated With Wet AMD in Patients That Require Persistent Anti-VEGF Therapy (MERITAGE)

Age Related Macular Degeneration

United Kingdom, Israel, United States
Bayer
Regeneron Pharmaceuticals

Terminated

A Study to Learn How Well Aflibercept Injected Into the Eye Works and How Safe it is When Given in Customized Treatment Intervals in Patients With an Eye Disease Called Neovascular Age-related Macular Degeneration After Start of Treatment (XPAND)

Neovascular (Wet) Age-related Macular Degeneration

Canada, United Kingdom
Manchester University NHS Foundation Trust
Topcon Corporation; Optos, PLC

Withdrawn

Sub-threshold Photocoagulation of Diabetic Macular Oedema (MEM)

Diabetic Macular Oedema

United Kingdom
University of Oxford
Pfizer

Completed

Intravitreal Macugen for Ischaemic Diabetic Macular Oedema (MIDME)

Diabetic Macular Oedema

United Kingdom
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Ranibizumab and Bevacizumab for Diabetic Macular Edema

Diabetic Macular Edema

United States, United Kingdom
Boehringer Ingelheim

Completed

A Study to Test Different Doses of BI 836880 in Patients With an Eye Disease Called Wet Age-related Macular Degeneration (wAMD)

Wet Macular Degeneration

United Kingdom, United States, Germany
VisionCare, Inc.

Completed

A Study of an Implantable Miniature Telescope in Patients With With End-Stage AMD

End Stage Macular Degeneration

United Kingdom
Novartis Pharmaceuticals

Terminated

The Efficacy of Oral Everolimus in Patients With Neovascular Age-related Macular Degeneration

Age-related Macular Degeneration | Choroidal Neo-Vascular Age-onset Macular Degeneration

United Kingdom, United States
Portsmouth Hospitals NHS Trust

Completed

Epiretinal Membrane and Cystoid Macular Oedema Post-cataract Surgery (EPIC)

Epiretinal Membrane | Pseudophakic Cystoid Macular Oedema

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Macusoft

Not yet recruiting

Artificial Intelligence Diagnostic Aid (AID)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Macular Degeneration

United Kingdom
Johns Hopkins University

Terminated

Pro-permeability and Pro-fibrosis Factors in the Aqueous of Patients With Retinal Diseases (P3F2)

Macular Edema | Fibrosis of the Retina

United States
LumiThera, Inc.

Completed

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE II)

Dry Age-related Macular Degeneration

United Kingdom, Spain, France, Germany, Italy
VisionCare, Inc.

Recruiting

Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular Degeneration

Age-Related Macular Degeneration | AMD

Italy, Ireland, Spain, Germany, United Kingdom
Novartis

Completed

Safety and Tolerability of an Intravenous Infusion of ACZ885 in Patients With Wet Age-Related Macular Degeneration

Wet Age-Related Macular Degeneration

United Kingdom, Switzerland
Bayer

Completed

Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease (XTEND)

Wet Age-related Macular Degeneration

Canada, Spain, Sweden, Belgium, Argentina, Italy, Korea, Republic of, United Kingdom, China, Denmark, France, Norway, Colombia, Australia, Ireland, Switzerland, Thailand
University of Southampton
King's College London; Medical University of Vienna; University of Michigan; Imperial... and other collaborators

Active, not recruiting

Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - PINNACLE (PINNACLE)

Age-related Macular Degeneration

Austria, Switzerland, United Kingdom
Oxford University Hospitals NHS Trust

Recruiting

Performance of Long-wavelength Autofluorescence Imaging

Retinal Degeneration | Retinal Dystrophies | Retinal Disease

United Kingdom
Novartis Pharmaceuticals

Terminated

Brolucizumab Treatment Experience Study of Patients With nAMD in UK Routine Clinical Practice (BESRA)

Neovascular Age-related Macular Degeneration

United Kingdom
University of Oxford

Completed

Visual and Functional Assessment in Low Vision Patients

Age-related Macular Degeneration | Retinitis Pigmentosa | Inherited Retinal Dystrophies | Optic Nerve Pathology

United Kingdom
PanOptica, Inc.

Completed

Study of PAN-90806 Eye Drops, Suspension for Neovascular AMD

Neovascular Age-related Macular Degeneration

United States, Czechia, United Kingdom, Hungary, Latvia
Synergy Spine Solutions
MCRA

Not yet recruiting

Post-Market Data Collection to Evaluate the Performance of the Synergy Disc®

Cervical Degenerative Disc Disease

United Kingdom
Novartis Pharmaceuticals

Terminated

A Prospective, Observational, Multicentre, 2 Year Study Evaluating the Use of Eylea (Aflibercept) for the Treatment of Neovascular (Wet) Age-related Macular Degeneration in UK NHS Opthalmology Clinics

Wet Age-related Macular Degeneration

United Kingdom
Bayer
Regeneron Pharmaceuticals

Completed

Evaluation of Changes in Visual Acuity in Patients With Diabetic Macular Edema (DME) Starting Treatment With an Approved Anti-VEGF Therapy (POLARIS)

Macular Degeneration | Macular Edema | Ophthalmology

Slovakia, France, Germany, Spain, Russian Federation, United Kingdom, Portugal, Greece

Clinical Trials on Retinal Degeneration in United Kingdom

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