- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01876147
Visual and Functional Assessment in Low Vision Patients
A Randomised Crossover Study to Assess the Usability of Two New Vision Tests in Patients With Low Vision, and Relationship of the Measures to Daily Living Tasks.
Study Overview
Status
Detailed Description
Assessing very low vision accurately is becoming increasingly important with the increase in research in this area, such as using retinal implants to restore vision. Without being able to accurately measure the change in vision before and after treatment, it is not possible to fully assess the effect of treatment.
The Freiburg Vision Test (FrACT) is a computer based test developed to assess patients down to the LP level. It has been used in research in recent years. The FrACT is suitable for research but is not suitable for a clinical setting. The Berkeley Rudimentary Vision Test (BRVT) works on a similar principal as the FrACT but consists of hand held cards shown to the patient. Little work has been completed on how well the BRVT test works. Results from FrACT and BRVT will be compared in a group of patients with very low vision. This is important to establish how easily research results can be applied to a clinical setting.
Patients will also be asked to complete a daily living survey to better understand the impact of such poor vision on the ability to carry out day to day tasks. This understanding will help guide low vision services for patients as well as help direct low vision research to achieve a useful level of functional vision.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
Oxfordshire
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Oxford, Oxfordshire, United Kingdom, OX3 9DU
- Oxford University Hospitals NHS Trust
-
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Snellen VA or equivalent ≤ 6/60 in both eyes
- Patient has capacity to give consent and to undertake vision tests
Exclusion Criteria:
- Diagnosis of functional vision loss
- Unwilling and/or unable to sign informed consent and complete the vision tests
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
---|
Order of vision tests 1
Undergo testing with BRVT first, FrACT second.
|
Order of vision tests 2
Undergo testing with FrACT first, BRVT second.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Comparison of VA measured with FrACT and BRVT vision tests
Time Frame: Single visit
|
Single visit
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Relationship between VA and ability to carry out daily living tasks.
Time Frame: Single time point
|
Results from a daily living skills survey will be related to VA measured by FrACT testing.
|
Single time point
|
Collaborators and Investigators
Sponsor
Publications and helpful links
Helpful Links
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- OxfordVA2013
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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