Clinical Trials on Retinitis Pigmentosa in Canada

Total 121 results

QLT Inc.

Completed

Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 65 Protein (RPE65)

Retinitis Pigmentosa (RP)

Canada, Ireland
MeiraGTx UK II Ltd
Janssen, LP

Active, not recruiting

Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR)

Retinitis Pigmentosa

United States, United Kingdom, Canada
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

Belgium, Canada, United States, Israel, United Kingdom, Spain, Denmark, France, Italy, Netherlands, Switzerland
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

United States, Canada, Israel, United Kingdom, Spain, Denmark, France, Belgium, Italy, Netherlands, Switzerland
University Health Network, Toronto
Foundation Fighting Blindness

Unknown

Observational Study of the Argus® II Retinal Prosthesis System

Retinitis Pigmentosa

Canada
NightstaRx Ltd, a Biogen Company

Completed

Natural History of the Progression of X-Linked Retinitis Pigmentosa (XOLARIS)

X-Linked Retinitis Pigmentosa

United States, France, United Kingdom, Finland, Netherlands, Germany, Canada
QLT Inc.

Completed

Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01)

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

Canada, United States, Germany, Netherlands, United Kingdom
NightstaRx Ltd, a Biogen Company

Enrolling by invitation

Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa (SOLSTICE)

Choroideremia | X-Linked Retinitis Pigmentosa

United States, United Kingdom, Netherlands, Germany, France, Brazil, Canada, Denmark, Finland
QLT Inc.

Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

United States, Canada, Germany, Netherlands, United Kingdom
QLT Inc.

Completed

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Leber Congenital Amaurosis (LCA) | Retinitis Pigmentosa (RP)

United States, Canada, Denmark, Germany, Netherlands, Switzerland, United Kingdom
Jaeb Center for Health Research
Foundation Fighting Blindness

Active, not recruiting

Rate of Progression in EYS Related Retinal Degeneration (Pro-EYS)

Eye Diseases | Retinitis Pigmentosa

United States, Israel, Finland, Canada, France, Germany, Netherlands
Jaeb Center for Health Research
Foundation Fighting Blindness

Active, not recruiting

Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A)

Usher Syndrome, Type 2A | Retinitis Pigmentosa 39

United States, Canada, France, Germany, Netherlands, United Kingdom
Jaeb Center for Health Research
Usher 1F Collaborative; Marjorie C. Adams Foundation

Active, not recruiting

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F (RUSH1F)

Retinal Degeneration | Retinitis Pigmentosa | Eye Diseases, Hereditary

Switzerland, United States, Germany, Netherlands, Canada, France, Israel
Universidad de Granada

Completed

Effectiveness of a Cognitive-behavioral Program of Coping With Psychological Stress in People With Retinitis Pigmentosa (RCT)

Stress, Psychological | Vision Disorders | Self Efficacy | Psychopathy

Spain
Jaeb Center for Health Research
Foundation Fighting Blindness

Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants (Uni-Rare)

Retinitis Pigmentosa | Inherited Retinal Degeneration

United States, United Kingdom, France, Brazil, Canada, Finland, Israel, Mexico, Netherlands, Switzerland, Australia
Johns Hopkins University
Mayo Clinic; Medical University of Graz; Radboud University Medical Center; University... and other collaborators

Recruiting

Oral N-acetylcysteine for Retinitis Pigmentosa (NAC Attack)

Retinitis Pigmentosa

United States, Austria, Mexico, Netherlands, United Kingdom, Germany, Canada, Switzerland
Circassia Limited
Adiga Life Sciences, Inc.

Completed

Evaluating the Efficacy of Ragweed-SPIRE Following Exposure to Ragweed Allergen in an Environmental Exposure Chamber

Seasonal Allergic Rhinitis

Canada
Circassia Limited
Adiga Life Sciences, Inc.

Completed

Safety Study of Ragweed-SPIRE in Subjects With Ragweed Allergies and Asthma

Asthma | Seasonal Allergic Rhinitis

Canada
ProQR Therapeutics

Terminated

An Open-Label Extension Study to Evaluate Safety & Tolerability of QR-421a in Subjects With Retinitis Pigmentosa (HELIA)

Retinitis Pigmentosa | Usher Syndrome Type 2

United States, Canada, France
Rhythm Pharmaceuticals, Inc.

Completed

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the MC4R Pathway

Bardet-Biedl Syndrome | POMC Deficiency

Netherlands, United States, Germany, Canada, Puerto Rico, United Kingdom
Sanofi

Completed

Study Evaluating the Efficacy and Safety of Fexofenadine in Subjects Suffering From Seasonal Allergic Rhinitis in Presence of Pollutants (FEXPOLSAR)

Rhinitis Seasonal

Canada
ProQR Therapeutics

Completed

Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Stellar)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Canada, France
Sun Pharma Advanced Research Company Limited

Completed

Efficacy and Safety of SPARC1310 in Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Canada
Novartis

Completed

A Study to Compare the Efficacy of QAV680 Against Placebo in Treating Seasonal Allergic Rhinitis in an Environmental Exposure Chamber

Seasonal Allergic Rhinitis

Canada
MEDA Pharma GmbH & Co. KG

Completed

MP-AzeFlu Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
Ligand Pharmaceuticals

Completed

Compare CE-Budesonide Nasal Solution & Rhinocort Aqua in an EEC Study of AR

Seasonal Allergic Rhinitis

Canada
Ligand Pharmaceuticals

Completed

Compare Captisol-Enabled (CE) Budesonide + Azelastine Nasal Solution and Rhinocort Aqua + Astelin in an Environmental Exposure Chamber (EEC) Study of Allergic Rhinitis

Seasonal Allergic Rhinitis

Canada
Sandoz

Terminated

Study to Compare the Pharmacokinetics of Fixed-Dose Combination of Mometasone + Azelastine Nasal Spray to Mometasone and Azelastine Nasal Sprays in Adolescents and Young Adults With Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Canada
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Single and Multiple Dose Study to Explore the Safety of JNJ-38224342 in Healthy Patients and Patients With Seasonal Allergies

Seasonal Allergic Rhinitis

Canada
Bayer
Queen's University

Completed

A Randomized, Placebo Controlled Study to Determine the Efficacy and Speed of a Nasal Spray in Allergen Induced Seasonal Allergic Rhinitis (GEYSER)

Seasonal Allergic Rhinitis

Canada
Allergy Therapeutics

Completed

Follow-up Investigation of Efficacy of Ragweed MATAMPL,and Placebo in Patients With Ragweed-induced Seasonal Allergic Rhinitis

Type I Hypersensitivity

Canada
Opella Healthcare Group SAS, a Sanofi Company

Completed

A Placebo-controlled Study of 2-day Pre-treatment With Fexofenadine in Seasonal Allergic Rhinitis (FEXPRESAR)

Seasonal Allergic Rhinitis

Canada
MEDA Pharma GmbH & Co. KG

Completed

Dymista Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
Glenmark Pharmaceuticals Ltd. India

Completed

Efficacy and Safety of Fixed Dose Combination (FDC) of Olopatadine Hydrochloride and Mometasone Furoate Nasal Spray (Molo; Also Referred as GSP 301) in the Treatment of Seasonal Allergic Rhinitis (SAR) (GSP 301- PoC)

Seasonal Allergic Rhinitis

Canada
Altamira Medica Ltd.

Completed

Efficacy and Safety of AM-301 on Allergic Symptoms of Perennial Allergic Rhinitis Sufferers

Rhinitis, Allergic | Perennial Allergic Rhinitis

Canada
MEDA Pharma GmbH & Co. KG

Completed

Azelastine Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
UCB Pharma

Completed

A Study to Compare the Efficacy of Levocetirizine to Placebo in Reducing Symptoms of Seasonal Allergic Rhinitis (SAR) in Sensitive Subjects Exposed to Ragweed Pollen

Rhinitis | Allergic | Seasonal

Canada
Faes Farma, S.A.
Allied Research International

Completed

PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)

Seasonal Allergic Rhinitis | Hay Fever | Rhinoconjunctivitis

Canada
Allergy Therapeutics

Terminated

Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis

Type I Hypersensitivity

Canada
Stallergenes Greer
Syneos Health

Completed

Safety Study of Sublingual Immunotherapy Tablets of House Dust Mite Allergen Extracts in Adolescents

House Dust Mite Allergic Rhinitis

Canada
GlaxoSmithKline

Completed

To Investigate the Safety, Pharmacodynamics and Effect on Allergic Reactivity of the Toll-like Receptor 7 (TLR7) Agonist GSK2245035 in Subjects With Respiratory Allergies

Mild Asthma and Allergic Rhinitis

Canada
Stallergenes Greer

Completed

Efficacy and Safety of 100IR, 300IR, 500IR Sublingual House Dust Mite (HDM) Tablets in Allergic Rhinitis Environment Exposure Chamber Model

House Dust Mites Allergic Rhinitis

Canada
AOBiome LLC
Integrium; Orange County Research Center

Completed

Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis

Allergic Rhinitis Due to Grass Pollen | Allergic Rhinitis | Healthy Volunteers

United States, Canada
GlaxoSmithKline

Completed

A Study to Assess Intranasal Repeat Dose Effect of Levocabastine in the Subjects With Allergic Rhinitis

Rhinitis, Allergic, Perennial and Seasonal

Canada
Afexa Life Sciences Inc

Completed

A Randomized, Double-blind, Placebo-controlled Study on the Effect of CVT-E002 in Patients With Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Canada
Circassia Limited
Adiga Life Sciences, Inc.

Completed

Study of Grass-SPIRE in Subjects With Grass Allergies and Asthma

Asthma | Seasonal Allergic Rhinitis

Canada
Dr. Anne Ellis

Recruiting

Tezepelumab in Allergic Rhinitis and Asthma Study (TEZARS) (TEZARS)

Asthma With Allergic Rhinitis

Canada
AllerPops Corp

Completed

AllerPops Reduce Nasal Symptoms in Adult Volunteers With Allergic Rhinitis

Allergic Rhinitis

Canada
Queen's University

Completed

Systemic Mechanisms in Allergic Rhinitis: Assessment of Metabolomic Outcomes. (NMR)

Allergic Rhinitis

Canada
McMaster University
St. Joseph's Healthcare Hamilton

Unknown

Repeat Dose Nasal Allergen Challenge

Allergic Rhinitis

Canada

Clinical Trials on Retinitis Pigmentosa in Canada

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