Clinical Trials on Rheumatism

Total 9597 results

Novartis Pharmaceuticals

Recruiting

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR) (REPLENISH-EXT)

Polymyalgia Rheumatica

Australia
Novartis Pharmaceuticals

Recruiting

Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Intravenous Secukinumab in Patients With GCA or PMR

Giant Cell Arteritis | Polymyalgia Rheumatica

United States
Aarhus University Hospital
Odense University Hospital; Zealand University Hospital; Rigshospitalet, Denmark and other collaborators

Recruiting

DANIsh VASculitis Database (DANIVAS) (DANIVAS)

Giant Cell Arteritis | Polymyalgia Rheumatica

Denmark
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Impact of the Spatial Resolution of Several Contrast-enhanced 3D T1-WI Sequences When Diagnosing Giant Cell Arteritis (GCA) (SPARTA)

Giant Cell Arteritis
Sint Maartenskliniek
ZonMw: The Netherlands Organisation for Health Research and Development; Dutch...

Recruiting

Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Recently Diagnosed (REDUCE-PMR-1)

Polymyalgia Rheumatica

Netherlands
Sparrow Pharmaceuticals

Recruiting

A Trial of Prednisolone in Combination With SPI-62 or Placebo in Subjects With Polymyalgia Rheumatica (PMR)

Polymyalgia Rheumatica

Germany
University Hospital, Caen

Recruiting

Study of Circulating Microparticles in Giant Cell Arteritis (MicroGiant)

Giant Cell Arteritis | Acute Phase

France
Janssen Research & Development, LLC

Active, not recruiting

A Study to Evaluate Guselkumab for the Treatment of Participants With New-onset or Relapsing Giant Cell Arteritis (THEIA)

Giant Cell Arteritis

United States, Canada, Belgium, Israel, Italy, Germany, France, Spain, Poland
University of Alberta

Completed

Use of Gallium-68 HA-DOTATATE PET/CT in Giant Cell Arteritis (GCA)

Giant Cell Arteritis

Canada
Universitaire Ziekenhuizen KU Leuven

Completed

Prospective Follow-up Study of the Aortic Diameter in Patients With Giant Cell Arteritis (ATACT)

Giant Cell Arteritis

Belgium
University Hospitals Bristol and Weston NHS Foundation...

Completed

Timed Release Tablet Prednisone in Polymyalgia Rheumatica

Polymyalgia Rheumatica

United Kingdom
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Determining Disease Activity Biomarkers in Individuals With Giant Cell Arteritis

Temporal Arteritis

United States, Canada
Sanofi
Regeneron Pharmaceuticals

Terminated

Evaluation of Efficacy and Safety of Sarilumab in Patients With GCA

Giant Cell Arteritis

Argentina, Estonia, France, United States, Australia, Belgium, Canada, Croatia, Denmark, Germany, Hungary, Israel, Italy, Netherlands, Portugal, Russian Federation, Slovenia, Spain, Sweden, Switzerland, United Kingdom
Centre Hospitalier Universitaire Dijon

Completed

Evaluation of PET/CT of Cephalic Arteries for the Diagnosis of Giant Cell Arteritis (Cervico-TEP et)

Giant Cell Arteritis

France
Hoffmann-La Roche

Completed

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).

Giant Cell Arteritis

Switzerland
University Hospital, Brest
Roche Chugai

Completed

Safety and Efficacy of tocilizuMAb Versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence SEMAPHORE

Polymyalgia Rheumatica

France
Hoffmann-La Roche

Completed

An Extension Study to Evaluate Long-Term Safety of Subcutaneous (SC) Tocilizumab in Participants With Giant Cell Arteritis (GCA)

Giant Cell Arteritis

France
University Hospital, Caen
University Hospital, Rouen; Central Hospital Saint Quentin; University Hospital... and other collaborators

Unknown

Giant Cell Arteritis and Anakinra Trial (GiAnT)

Giant Cell Arteritis

France
Bristol-Myers Squibb

Withdrawn

A Study to Evaluate Efficacy and Safety of Subcutaneous Abatacept With Steroid Treatment Compared to Steroid Treatment Alone in Adults With Giant Cell Arteritis (GCA)

Giant Cell Arteritis

Poland, United States, Spain, France, Austria, Belgium, Italy, Romania, Switzerland, Germany, Greece, Netherlands, Australia, Denmark, United Kingdom, Ireland, Bulgaria, Canada, Estonia, Serbia, Sweden
Hospital Universitario Marqués de Valdecilla
Schering-Plough

Unknown

Infliximab Therapy in Patients With Refractory Polymyalgia Rheumatica

Polymyalgia Rheumatica

Spain
Centocor, Inc.
The Cleveland Clinic

Terminated

A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Giant Cell Arteritis

Giant Cell Arteritis
NYU Langone Health

Recruiting

Autoimmune and Autoinflammatory Genetics Study

Autoimmune Disease | Autoinflammatory Disease | Rheumatic Disease | VEXAS Syndome

United States
Assistance Publique - Hôpitaux de Paris
Roche Pharma AG; Roche Chugai

Recruiting

Efficacy of Tocilizumab in Association to Steroids in Giant Cell Arteritis With Cerebro-vascular Involvement (TOGIAC)

Giant Cell Arteritis | Neurovascular Disorder

France
Centre Hospitalier Universitaire Dijon

Recruiting

Study of T Lymphocytes in Patients With Horton Disease (GAMAIT)

Horton Disease

France
AbbVie

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis (SELECT-GCA)

Giant Cell Arteritis (GCA)

United States, Australia, Austria, Belgium, Canada, Czechia, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Netherlands, New Zealand, Norway, Portugal, Romania, Russian Federation, Spain, Sweden, Switzerland, United...
Massachusetts General Hospital

Terminated

Ustekinumab for the Treatment of Giant Cell Arteritis (UGCA)

Giant Cell Arteritis | Horton's Disease | Temporal Arteritis

United States
University Hospital, Brest

Completed

Velocimetric Study of Temporal Arteries in Patients With Horton Disease Using Scan-Doppler (VELHOR)

Horton Disease

France
Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Secukinumab in Patients With New Onset of Giant Cell Arteritis Who Are in Clinical Remission (GigAINt)

Giant Cell Arteritis

Germany
Novartis Pharmaceuticals

Recruiting

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Giant Cell Arteritis (GCA)

Giant Cell Arteritis (GCA)

United States, Spain, Turkey, France, Hungary, Australia, Belgium, Germany, Israel, Argentina, Chile, Greece, Portugal, Bulgaria, Italy, Switzerland, Brazil, Czechia, Denmark, Estonia, Austria, Guatemala, United Kingdom, Finland, Russian... and more
Centre Hospitalier Universitaire Dijon

Recruiting

Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis (ULTRA)

Patients Relapsing Refractory Giant Cell Arteritis

France
RenJi Hospital

Completed

Tofacitinib as a GC Sparing Agent for Polymyalgia Rheumatica

Polymyalgia Rheumatica | Safety Issues | Effect of Drug

China
University Hospital, Limoges

Terminated

Pilot Study of the Impact of Giant Cell Arteritis and Its Treatment on the Autonomy of the Elderly in the First Year of Care (EPACAPA)

Giant Cell Arteritis in Dependency of Elderly

France
University Hospital, Limoges

Active, not recruiting

Chewing Gum Test for the Diagnosis of Giant Cell Arteritis (Horton's Disease) - ChewingHort (ChewingHort)

Horton Disease

France
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Interest of Medical Imaging in the Diagnostic Strategy Vis a Vis a Suspected Horton Disease (HORTIM)

Horton Disease

France
Svendborg Hospital
Odense University Hospital

Unknown

Polymyalgia Rheumatica and Giant Cell Arteritis

Giant Cell Arteritis | Polymyalgia Rheumatica

Denmark
Novartis Pharmaceuticals

Completed

A Placebo-controlled Phase 2 Trial to Investigate the Safety and Efficacy of Secukinumab in Giant Cell Arteritis (TitAIN)

Giant Cell Arteritis

Germany
Centre Hospitalier Universitaire de Nīmes

Completed

Collection and Analysis of the Clinical and Biological Characteristics of Patients Treated for Giant Cells ARTEitis (Horton's Disease) (CARTECEL)

Giant Cell Arteritis | Horton Disease

France
University Hospital, Brest

Completed

Lymphocyte and Cytokine Disturbances in Polymyalgia Rheumatica (TENOR-IMMUNO)

Polymyalgia Rheumatica

France
China National Center for Cardiovascular Diseases

Recruiting

Bi-atrial Versus Left Atrial Ablation for Patients With Rheumatic Mitral Valve Disease and Non-paroxysmal Atrial Fibrillation

Persistent Atrial Fibrillation

China
National Institutes of Health Clinical Center (CC)

Terminated

Aerobic Exercise in Women With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Autoimmune Disease | Rheumatic Disease | Lupus

United States
Bristol-Myers Squibb

Recruiting

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs

Psoriatic Arthritis

Italy, United States, Australia, Argentina, Brazil, Czechia, France, Hungary, Mexico, Russian Federation, China, Poland, Finland, Colombia, United Kingdom, Bulgaria, Taiwan, Chile, Romania, Spain, Ireland
AbbVie

Active, not recruiting

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD) (SELECT - PsA 1)

Psoriatic Arthritis

United States, Argentina, Australia, Belarus, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Estonia, Germany, Greece, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic... and more
AbbVie

Active, not recruiting

A Study Comparing Upadacitinib (ABT-494) to Placebo in Participants With Active Psoriatic Arthritis Who Have a History of Inadequate Response to at Least One Biologic Disease Modifying Anti-Rheumatic Drug (bDMARD) (SELECT - PsA 2)

Psoriatic Arthritis

United States, Belgium, Brazil, Canada, Chile, Czechia, France, Greece, Hungary, Italy, Japan, Netherlands, New Zealand, Portugal, Puerto Rico, Spain, United Kingdom
The Cleveland Clinic

Completed

Phase II Randomized Study of Glucocorticoids With or Without Methotrexate for Treatment of Giant Cell Arteritis

Giant Cell Arteritis
Butantan Institute
InCor - Instituto do Coração - HCFMUSP.

Withdrawn

Clinical Trial to Assess Safety and Immunogenicity of a Synthetic Vaccine Against Streptococcus Pyogenes

Rheumatic Fever
University of Bonn

Recruiting

Investigation of the Influence of the Human Microbiome on the Pathogenesis and Recurrence Probability in Giant Cell Arteritis (GCA-Biom)

Giant Cell Arteritis

Germany
University of Cambridge
Imperial College London; Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust and other collaborators

Active, not recruiting

PET Imaging of Giant Cell and Takayasu Arteritis (PITA)

Giant Cell Arteritis | Takayasu Arteritis

United Kingdom
National Institute of Arthritis and Musculoskeletal...

Recruiting

Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease

Rheumatic Disease

United States
Keele University
Norfolk and Norwich University Hospitals NHS Foundation Trust; University of... and other collaborators

Recruiting

Developing Allogeneic Musculoskeletal Therapies

Osteoarthritis

United Kingdom
Bournemouth University
Economic and Social Research Council, United Kingdom

Recruiting

A Qualitative Investigation of CLEAT Participants

Osteoarthritis

United Kingdom

Clinical Trials on Rheumatism

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Hong Kong

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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