Clinical Trials on SGLT-2 Inhibitor in China

Total 1025 results

Chinese PLA General Hospital

Unknown

Treatment of Chemotherapy Refractory Human Epidermalgrowth Factor Receptor-2( HER-2) Positive Advanced Solid Tumors (CART-HER-2)

Advanced HER-2 Positive Solid Tumors | Chemotherapy Refactory | HER-2 Antibody Inhibitor Therapy Refactory

China
Sichuan Academy of Medical Sciences

Recruiting

Dapagliflozin Delays the Loss of Renal Function in Peritoneal Dialysis Patients

Peritoneal Dialysis Complication | Renal Function Aggravated | Sodium-glucose Co-transporter-2 Inhibitors

China
Sun Jia

Completed

Effect of Dapagliflozin on Body Weight in Overweight Women Consuming Different Proportions of Carbohydrate Diet.

Overweight | Carbohydrate | Sodium-glucose Transporter 2 Inhibitors

China
Nanjing Medical University

Completed

Immune Checkpoint Inhibitors(ICPis)-Induced Endocrine Immune-related Adverse Events (irAEs)

Immune Checkpoint Inhibitor | Endocrine Toxicity

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast Cancer (RADIOCOM)

Chemotherapeutic Toxicity | Radiotherapy; Complications | PARP Inhibitor | Immune Checkpoint Inhibitor | Trastuzumab | Breast Cancer, Familial Male | CDK4/6 Inhibitor | Pertuzumab

China
Sun Yat-sen University

Recruiting

Safety and Efficacy of RX-af01 Combined With PD-1 Antibody

Solid Tumor | Intestinal Flora | Immune Checkpoint Inhibitor

China
Cancer Institute and Hospital, Chinese Academy...
Peking University; Peking University Cancer Hospital & Institute

Recruiting

68Ga-TCR-FAPI PET/CT in Patients With Various Types of Cancer

Malignant Tumor | Positron Emission Tomography | Fibroblast Activation Protein Inhibitor

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Perspective, Self-control Study on the Progression of Carotid Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up

Carotid Artery Plaque | Plaque, Atherosclerotic | Immune Checkpoint Inhibitors | Programmed Cell Death Protein 1 Inhibitor | Intimal Medial Thickness of Internal Carotid Artery

China
Zhongnan Hospital

Recruiting

68Ga-FAPI PET/CT in Malignant Tumors

Malignant Neoplasm | PET/CT | Fibroblast Activation Protein Inhibitor

China
Shanghai Tong Ren Hospital

Recruiting

Impact of Early PCSK9 Inhibitor on Heart After Acute Myocardium Infarction (PERFECT-AMI)

Early PCSK9 Inhibitor on Ventricular Remodling

China
Shanghai Chest Hospital
Bristol-Myers Squibb

Completed

Nivolumab Combined With Anlotinib as Re-challenge Treatment in Advanced NSCLC

NSCLC Stage IV | Checkpoint Inhibitor

China
Sun Yat-sen University

Recruiting

PD-1 Inhibitor Plus G-CSF in Recurrent/Metastatic NPC With First-line Treatment Failure

PD-1 Inhibitor | G-CSF

China
Lei Li

Completed

First-line Chemotherapy for Recurrent Cervical Cancer

Chemotherapy | Recurrent Cervical Carcinoma | Apatinib | Targeted Therapy | Persistent Advanced Cervical Carcinoma | Vascular Endothelial Growth Factor 2 Inhibitor

China
The First Affiliated Hospital of Dalian Medical...

Completed

Ticagrelor in Elderly Patients Undergoing Percutaneous Coronary Intervention

Percutaneous Coronary Intervention | Aged | Platelet Aggregation Inhibitors | Dual Anti-Platelet Therapy

China
Baodong Qin

Unknown

Effect of Chemotherapy on TMB in NSCLC

Chemotherapy Effect | Immunotherapy | Tumor Mutation Burden | PD-1/L1 Inhibitor

China
Peking University Third Hospital

Not yet recruiting

Stereotactic Body Radiotherapy Combined With Cadonilimab for Advanced Refractory Malignant Solid Tumors (SCARCE)

Advanced Solid Tumor | Efficacy | Safety | Stereotactic Body Radiotherapy | Immune Checkpoint Inhibitor

China
Second Affiliated Hospital, School of Medicine,...
Zhejiang Cancer Hospital; Sun Yat-sen University; Ningbo Medical Center Lihuili... and other collaborators

Recruiting

Multi-center Observational Study on the Progression of Atherosclerotic Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up

Plaque, Atherosclerotic | Programmed Cell Death Protein 1 Inhibitor

China
Beijing Children's Hospital
Capital Medical University

Completed

Estimation Method of 24-hour Urinary Sodium Excretion by Using Spot Urine for Chinese Population

Urinary Sodium Excretion | Salt Intakes

China
Suzhou Alphamab Co., Ltd.

Recruiting

Efficacy and Safety of KN057 Prophylaxis in Patients With Haemophilia A or B With Inhibitors

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Study of Recombinant Human Coagulation Factor VIIa for Injection (FⅦa) in Patients With Hemophilia.

Hemophilia A With Inhibitor | Hemophilia B With Inhibitor

China
The University of Hong Kong
Research Grant Council

Recruiting

Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B

Cirrhosis | NAFLD | Chronic Hepatitis b | Fibrosis, Liver | Empagliflozin | SGLT2 Inhibitors

Hong Kong
Sun Yat-sen University

Recruiting

G-CSF in Patients With Anti-PD-1-axis Therapy-resistant Recurrent or Metastatic Nasopharyngeal Carcinoma

PD-1 Inhibitor | Granulocyte Colony-Stimulating Factor

China
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Corticosteroids in Combination With Ruxolitinib in the Management of Checkpoint Inhibitor Pneumonia

Severe Checkpoint Inhibitor Pneumonitis

China
Vigonvita Life Sciences

Completed

A Study of the Hemodynamic Interactions of TPN171H Tablets & Alcohol in Healthy Male Subjects

Erectile Dysfunction | Alcohol | Phosphodiesterase Inhibitor

China
Sun Yat-sen University

Recruiting

A Study of Gefitinib With or Without Apatinib in Patients With Advanced Non-squamous Non-Small-Cell Lung Cancer Harboring EGFR Mutations

EGFR Tyrosine Kinase Inhibitors Plus VEGFR Inhibitors

China
Shanghai Jiao Tong University School of Medicine

Completed

Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma

Oral Cancer | VEGFR2 Inhibitor | Programmed Cell Death 1 Inhibitor | Inductive Therapy

China
Nanfang Hospital, Southern Medical University

Recruiting

Prospective Study on the Efficacy and Safety of Bronchoalveolar Lavage Combined With Pathogen Metagenomic Sequencing Technology in the Diagnosis of Immune Checkpoint Inhibitor Associated Pneumonia

Immune Checkpoint Inhibitor Associated Pneumonia

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Phase Ib/II Study Confirmed Inhibition of Autophagy Synergizes Anti-tumor Effect of High Dose CDK4/6i

Inhibition of Autophagy Synergizes Anti-tumor Effect

China
Fudan University

Recruiting

Sintilimab Combined With Modified FLOT Regimen in the Treatment of Metastatic Gastric Cancer

Gastric Cancer | Chemotherapy Effect | Immune Checkpoint Inhibitor

China
Peking Union Medical College Hospital
Geneplus-Beijing Co. Ltd.

Active, not recruiting

Exploratory Study on the Therapeutic Effect Prediction Model of Advanced BTC Immunotherapy

Biliary Tract Cancer | Predictive Cancer Model | Immune Checkpoint Inhibitor

China
Xinqiao Hospital of Chongqing

Recruiting

Efficacy and Safety of Super-hyperfractionation Pulse Radiotherapy Combined With ICIs for Advanced NSCLC

Lung Cancer | Radiotherapy | Immune Checkpoint Inhibitor

China
First People's Hospital of Hangzhou

Recruiting

A RCT of the Efficacy of Vonoprazan 20mg QD in the Treatment of Helicobacter Pylori Infection (VATH-1)

Helicobacter Pylori Infection | Proton Pump Inhibitor | Vonoprazan

China
Zhejiang Cancer Hospital

Recruiting

Dalpiciclib Combination With Fulvestrant and Compound Gossyfol Acetate Tablets in Women With CDK4/6 Inhibitor-refractory HR-positive HER-2 Negtive Metastatic Breast Cancer: a Phase 2 Clinical Trial.

Advanced HR-positive and HER2-negative Breast Cancer; CDK4/6 Inhibitor Treatment Failed

China
Henan Cancer Hospital

Recruiting

Toripalimab Plus FLOT in Locally Advanced Gastric Cancer

Chemotherapy | Immune Checkpoint Inhibitor | Locally Advanced Gastric Carcinoma

China
Chen Xiaoping

Completed

Postoperative Adjuvant Immunotherapy for Hepatocellular Carcinoma: Risk Factor Analysis and Prognostic Modelling

Hepatocellular Carcinoma | Checkpoint Inhibitor | Adjuvant Immunotherapy

China
Jiangsu Gensciences lnc.

Recruiting

SS109 and NovoSeven ® PK / PD Profile, and Preliminary Efficacy and Safety of SS109 on Demand Treatment

Hemophilia | Hemophilia A With Inhibitor | Male | Hemophilia B With Inhibitor

China
RenJi Hospital

Recruiting

Bladder Sparing Treatment of Tislelizumab, Gemcitabine and Cisplatin for Patients With PD-L1 Positive Muscle Invasive Bladder Cancer

Urothelial Carcinoma Bladder | PD-1 Inhibitor

China
Fujun Zhang

Recruiting

Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma (RAFAS-001)

Sarcoma,Soft Tissue | Brachytherapy | Poly(ADP-ribose) Polymerase Inhibitors

China
Sun Yat-sen University

Recruiting

HAIC Combined With Lenvatinib and PD-1 Inhibitor in Infiltrative Hepatocellular Carcinoma

Hepatocellular Carcinoma | PD-1 Inhibitor | Lenvatinib | Hepatic Arterial Infusion Chemotherapy

China
Peking Union Medical College Hospital

Recruiting

Regorafenib Combined With PD-1 Inhibitor Therapy for Second-line Treatment of Hepatocellular Carcinoma

Hepatocellular Carcinoma | PD-1 Inhibitor | Regorafenib

China
Tianjin Chest Hospital

Recruiting

Effect of Evolocumab Added to Moderate-Intensity Statin Therapy on LDL-C Lowering and Cardiovascular Adverse Events in Patients With Acute Coronary Syndrome (EMSIACS)

Acute Coronary Syndrome | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor

China
AstraZeneca

Recruiting

Ondexxya for Intravenous Injection 200mg Drug Use Result Investigation (All Case Investigation)

Life Threatening Bleeding | Factor Xa Inhibitor

Japan
First People's Hospital of Hangzhou

Not yet recruiting

The Efficacy of Chemotherapy Combined With Immunocheckpoint Inhibitors in Advanced Biliary Malignancies

Biliary Tract Cancer | Gemcitabine | Immune Checkpoint Inhibitors

China
First People's Hospital of Hangzhou
Hangzhou Cancer Hospital

Recruiting

SBRT Combined With PD-1 Inhibitor and Thoracic Hyperthermia for Advanced NSCLC

Stereotactic Body Radiation Therapy; PD-1 Inhibitor; Hyperthermia; NSCLC

China
Peking Union Medical College Hospital

Recruiting

irAE Prediction of Anti-PD-1/L1 in Lung Cancer

Lung Cancer | Immune Checkpoint Inhibitors

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Correlation Between Pre-transplant ICI Exposure and Post-transplant Graft Rejection

Hepatocellular Carcinoma | Graft Rejection | Immunotherapy | Immune Checkpoint Inhibitor

China
Zhang Xiaofeng,MD

Active, not recruiting

A RCT of the Efficacy of Tegoprazan 50mg QD in the Treatment of Helicobacter Pylori Infection ( TATH-1 ) (TATH-1)

Helicobacter Pylori Infection | Proton Pump Inhibitor | Vonoprazan

China
Guangdong Provincial People's Hospital
Guangzhou Sport University

Completed

Evaluating the Impact of Baduanjin Exercise Intervention on Quality of Life in Breast Cancer Survivors Receiving Aromatase Inhibitor Therapy

Breast Cancer Survivors Receiving Aromatase Inhibitor Therapy

China
Fudan University

Recruiting

Tislelizumab Combing Chemoradiotherapy in Recurrent Cervical Cancer

Cervical Cancer | Chemoradiotherapy | Immune Checkpoint Inhibitor

China
Ruijin Hospital

Withdrawn

Proton Pump Inhibitor Prevent Dual Antiplatelet Agents Induced Gastrointestinal Ulcer After Coronary Artery Bypass Graft (DACAB-GI-2)

Gastric Ulcer Induced by Antiplatelet Agent | Ulcer of the Gastrointestinal Tract | Proton Pump Inhibitor

China

Clinical Trials on SGLT-2 Inhibitor in China

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