Clinical Trials on SGLT-2 Inhibitor in Ireland

Total 333 results

Pharvaris Netherlands B.V.

Active, not recruiting

Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (HAE CHAPTER-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Poland, Germany, Austria, Bulgaria, Canada, Ireland, Italy, United Kingdom
Pendulum Therapeutics

Terminated

Placebo-Controlled Clinical Nutrition Study of the Metabolic Effects of Food Product WBF-0011 in Type 2 Diabetes

Type 2 Diabetes Mellitus

Ireland
University of Limerick

Active, not recruiting

BioDulse II: The Effect of an Irish Seaweed Protein Extract on Glucose Control in Adults With Type 2 Diabetes

Type 2 Diabetes

Ireland
Imperial College London

Recruiting

Medication Following Bariatric Surgery for Type 2 Diabetes Mellitus (BY-PLUS)

Obesity | Type 2 Diabetes

Ireland
Neurovalens Ltd.
University College Dublin; Exploristics Ltd; Compliance Solutions Ltd.

Completed

Effect of VeSTAL Device in Type 2 Diabetes Mellitus

Metabolic Syndrome | Type 2 Diabetes

Ireland
University College Dublin

Completed

Dipeptidyl Peptidase-4 Inhibition in Psoriasis Patients With Diabetes (DIP): A Randomized Clinical Trial. (DIP)

Type 2 Diabetes Mellitus | Psoriasis

Ireland
University of Akureyri
Western Norway University of Applied Sciences

Completed

Effectiveness of Nurse-coordinated Follow-up Program in Primary Care for People at Risk for T2DM

Cardiovascular Risk Factor | Primary Health Care | Pre-diabetes | T2DM (Type 2 Diabetes Mellitus)

Iceland
National University of Ireland, Galway, Ireland
Irish Endocrine Society

Completed

Exogenous Glucose Oxidation Breath Test (EGOBT)

Diabetes Mellitus, Type 2

Ireland
Solvay Pharmaceuticals

Terminated

Fenofibrate and Metformin Insulin Sensitivity in Type 2 Diabetics Study

Type 2 Diabetes | Dyslipidemia

Finland, Ireland, Italy
MacroGenics

Recruiting

A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer Recurrent | Immunotherapy | Androgen-Independent Prostatic Cancer | Androgen-Resistant Prostatic Cancer | Hormone Refractory Prostatic Cancer | Immune Checkpoint Inhibitor | Androgen-Independent Prostatic Neoplasms | Androgen-Insensitive Prostatic Cance | Inhibitory Checkpoint Molecule

United States, Spain, France, Belgium, United Kingdom, Poland, Georgia, Bulgaria, Puerto Rico, Australia
CSL Behring

Completed

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Emphysema | Alpha 1-proteinase Inhibitor Deficiency

Australia, Canada, Czech Republic, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden
University College Dublin

Recruiting

Effects of Seaweed Extract on Blood Glucose Response to Sucrose

Diabetes Mellitus, Type 2 | Glucose Intolerance | Healthy Diet | Postprandial Hyperglycemia

Ireland
University College Dublin
Eli Lilly and Company; Merck Sharp & Dohme LLC; Royal College of Physicians; Irish...

Completed

The Differential Effects of Diabetes Therapy on Inflammation

Diabetic Nephropathy | Type 2 Diabetes

Ireland
German Breast Group
Pfizer; AGO Study Group; Breast International Group; NSABP Foundation Inc

Completed

A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery (PENELOPE-B)

Breast Cancer | Hormonreceptor Positive | Her2-normal | Postneoadjuvant Treatment With CDK 4/6 Inhibitor | CPS-EG Score

United States, Australia, Austria, Canada, France, Germany, Ireland, Japan, Korea, Republic of, Spain, United Kingdom
Pfizer

Terminated

A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug Given With Canagliflozin In Adults With Type 2 Diabetes Mellitus Taking Metformin

Type 2 Diabetes Mellitus

United States
Novo Nordisk A/S

Completed

Observational Study to Evaluate the Safety of Levemir® in Patients With Diabetes (PREDICTIVE™)

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Ireland, United Kingdom
Pfizer

Completed

A Multiple Dose Study Of PF-04620110 In Type 2 Diabetes Patients

Type 2 Diabetes Patients

United States
Health Service Executive, Ireland

Recruiting

Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study. (D-FOREST)

Personality Disorders | Cardiovascular Diseases | Obesity | Schizophrenia | Frailty | Recovery | Psychosis | Violence | Type II Diabetes | Treatment-resistant Schizophrenia | Forensic Psychiatry | Outcome Measure

Ireland
Swedish Orphan Biovitrum
Cerner Enviza

Completed

rFVIIIFc (Elocta®) ITI Chart Review in Patients With Haemophilia A

Hemophilia A With Inhibitor

France, Ireland, Italy, Norway, Germany, Kuwait, Saudi Arabia, Switzerland
Rhode Island Hospital

Completed

Smoking Cessation Intervention for Diabetic Patients (SSTOP)

Smoking | Type 2 Diabetes

United States
University of Aberdeen
NHS Grampian; Chief Scientist Office of the Scottish Government

Completed

Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study (FILMS)

Stage 2 or 3 Full Thickness Macular Hole

United Kingdom, Ireland
Rhode Island Hospital

Completed

Brief Alcohol Intervention to Reduce At-Risk Drinking Among Type 2 Diabetics (SUGAR)

Type 2 Diabetes | At-risk Drinking

United States
Shire
PPD

Completed

Blinded Safety & Efficacy Placebo Controlled Study of Icatibant for Angiotensin Converting Enzyme Inhibitor Induced Angioedema

Angiotensin Converting Enzyme Inhibitor Induced Angioedema

United States, Canada, United Kingdom, Israel
The Miriam Hospital

Recruiting

Feasibility of Yoga for Type-2 Diabetes

Type2 Diabetes

United States
Northwell Health

Completed

Metformin Use and Vitamin B12 Deficiency

Type 2 Diabetes Mellitus | Vitamin B12 Deficiency

United States
Novo Nordisk A/S

Completed

PROPACT: Retrospective Prophylaxis Patient Case Collection (PROPACT)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Slovakia, Spain, Argentina, Germany, Croatia, Italy, Canada, United Kingdom, Ireland, Sweden, France, United States, Czech Republic, Switzerland
Valbiotis
Institut Pasteur de Lille; Biofortis Mérieux NutriSciences

Completed

Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes (TOTUM-63 TWO)

Obesity | Disease | Insulin Resistance | Type 2 Diabetes | Hypertriglyceridemia | Prediabetes

France, Ireland, Serbia, Slovenia
Speedel Pharma Ltd.

Completed

Phase IIa Study to Investigate the Efficacy and Safety of SPP635 in Diabetic and Hypertensive Patients With Albuminuria

Hypertension | Type II Diabetes Mellitus

Ireland
Cheryl Rosenfeld, DO
Amylin Pharmaceuticals, LLC.

Unknown

Efficacy Study of High Dose Symlin to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Pfizer

Completed

Study Of Two Dosing Regimens Of PF-04937319 Compared To An Approved Agent (Sitagliptin) In Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Pfizer

Completed

Study To Evaluate The Effect Of Renal Impairment On The Pharmacokinetics Of PF-04991532

Healthy | Type 2 Diabetes Mellitus

United States
Shire

Terminated

Evaluation of Ecallantide for Treatment of Angiotensin Converting Enzyme (ACE) Inhibitor Induced Angioedema

ACE Inhibitor Induced Angioedema

United States
AstraZeneca
Eli Lilly and Company

Completed

Efficacy of Once-Weekly Exenatide Versus Once or Twice Daily Insulin Detemir in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Ireland, United Kingdom
Fractyl Health Inc.

Recruiting

Evaluation of the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects With Type 2 Diabetes on Insulin Therapy (REVITALIZE 1)

Type 2 Diabetes

United States, Belgium, Ireland, Italy, Netherlands, Switzerland, Spain, France, United Kingdom
Pfizer

Completed

A Phase 1 Single/Multiple Dose Study Of PF-06293620 To Assess Safety, Tolerability And Pharmacokinetics In Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
AstraZeneca
Astra Zeneca, Bristol-Myers Squibb

Completed

Effects of Dapagliflozin on Kidney Function (Glomerular Filtration Rate) in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States, Netherlands, Canada
Neurovalens Ltd.
University College Dublin; Clinical Trial Mentors; CS Lifescience

Active, not recruiting

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Improving Glycemic Control in Adults With Type 2 Diabetes Mellitus

Type 2 Diabetes

United States, Ireland
The Miriam Hospital
Brown University; Tufts Medical Center

Completed

Gene x Behavior Interaction in the Look AHEAD Study

Obesity | Type 2 Diabetes

United States
Hiantis Srl
Sciensano; Genefirst LTD

Completed

Evaluation of in Vitro Devices on Self-collected Vaginal Swab and Urine Sample for Testing of Human Papilloma Virus (EU-VALHUDES)

Neoplasms | Neoplasms by Histologic Type | Carcinoma in Situ | Neoplasm Cervix | Cervical Intraepithelial Neoplasia Grade 2/3 | Carcinoma Cervix Uterine

Italy, Ireland, United Kingdom
The Miriam Hospital
Rhode Island Hospital; University of Massachusetts, Lowell

Completed

Yoga as a Complementary Therapy for Adults With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States
Pfizer

Completed

Multiple Dose Study Of PF-05231023 In Adult Subjects Who Have Poor Lipid Control With And Without Type 2 Diabetes Mellitus

Diabetes Melliuts, Type 2

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...
Churchill Hospital

Completed

Evaluating Atorvastatin With Omega-3 Fatty Acids in Cardiovascular Risk Reduction in Patients With Type 2 Diabetes (AFORRD)

Diabetes, Type 2

United Kingdom
Centre Hospitalier Universitaire de la Réunion

Unknown

Translation, Cultural Adaptation and Validation of the Creole Versions of the EQ-5D and the SF-36 Questionnaires in Patients With Type II Diabetes in Reunion Island, Martinique and Guadeloupe (CreoQol)

Diabetes Mellitus, Type 2

France
Wellstat Therapeutics

Completed

Safety and Efficacy Study of PN2034 in Type 2 Diabetes Patients on Concomitant Rosiglitazone and Metformin (or Avandamet)

Type 2 Diabetes Mellitus

United States
University of Bologna
Charite University, Berlin, Germany; Institut National de la Santé Et de la... and other collaborators

Recruiting

Monitoring COVID-19 Vaccination Response in Fragile Populations (ORCHESTRA-4)

SARS CoV 2 Infection | Vaccination; Infection | Breakthrough Infection

Argentina, Gabon, India, Ireland, Italy, Luxembourg, Netherlands, Spain
Eli Lilly and Company

Completed

A Study for Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Brazil, Canada, Mexico, India, Australia, China, Korea, Republic of
vTv Therapeutics

Completed

A 6 Week Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of GK1-399 in Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
vTv Therapeutics

Completed

A Study to Evaluate Safety and Efficacy of TTP273 for 12 Weeks in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Valeritas, Inc.
Integrated Medical Development

Completed

Effectiveness of V-Go™ for Patients With Diabetes in a Real-world Setting (SIMPLE)

Type 2 Diabetes Mellitus

United States
ConjuChem

Terminated

Dose-Ranging Study to Evaluate Efficacy and Safety of Weekly CJC-1134-PC in Patients With T2DM on Metformin Monotherapy

Type 2 Diabetes Mellitus (T2DM)

United States, Canada

Clinical Trials on SGLT-2 Inhibitor in Ireland

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