Clinical Trials on Seizure Disorder

Total 146207 results

National Institute of Neurological Disorders and...

Terminated

The Role of Serotonin in Seizures

Epilepsy | Seizures

United States
National Institute of Neurological Disorders and...

Completed

Role of Hormones in Susceptibility to Seizures in Women With Epilepsy

Epilepsy

United States
National Institute of Neurological Disorders and...

Completed

Reducing Seizure Frequency Using Cooling of the Head and Neck

Epilepsy | Seizures

United States
Brain Sentinel
Nationwide Children's Hospital

Terminated

A Health Economic Study Evaluating the Brain Sentinel® GTC Seizure Detection and Information Systems Impact on Epilepsy and Healthcare Utilization

Epilepsy

United States
Washington University School of Medicine

Completed

The Impact of Electroencephalographic (EEG) Seizure Treatment in Neonatal Encephalopathy

Seizures | Encephalopathy

United States
Upsher-Smith Laboratories

Completed

Open-label Extension Study to Evaluate the Safety of USL255 in Patients With Refractory Partial-onset Seizures

Epilepsy

Australia, Canada, Poland, United States, Belgium, Spain, Argentina, Israel, India, South Africa, Greece, Russian Federation, Chile, New Zealand, Germany
Upsher-Smith Laboratories

Completed

Study to Evaluate the Safety and Effectiveness of USL255 in Patients With Refractory Partial-onset Seizures

Epilepsy

United States, Australia, Poland, Belgium, Spain, Argentina, Israel, India, South Africa, Greece, Russian Federation, Chile, Germany, New Zealand, Hungary, Canada
National Center for Complementary and Integrative...

Completed

Double Blind, Crossover Study of Fish Oil [EPA and DHA] for Intractable Partial Seizures (FOS)

Epilepsy

United States
GlaxoSmithKline

Withdrawn

GW273225 Therapy Added To Current Seizure Treatments In Patients With Partial Seizures

Epilepsy

United States
SK Life Science, Inc.

Terminated

Carisbamate Retention Study (CaReS): Comparative Study on the Long Term Effectiveness, Safety and Tolerability of Carisbamate Compared to Two Other Frequently Prescribed Anti-epileptic Drugs (AEDs) in Patients With Epilepsy.

Epilepsy | Seizures
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Topiramate in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Epilepsy | Seizures
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Effectiveness and Safety of Topiramate Compared With a Standard Therapy in Patients Newly Diagnosed With Epilepsy

Epilepsy | Seizures
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Topiramate as "Add on" Treatment in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Epilepsy | Seizures
Sohag University

Recruiting

Combined Ketamine and Midazolam for Generalized Convulsive Status Epilepticus (Ket-Mid)

Generalized Convulsive Status Epilepticus

Egypt
Assistance Publique - Hôpitaux de Paris

Terminated

Perampanel in Focal Status Epilepticus (PEPSI)

Epilepticus; Status, Focal Motor

France
Cerebral Therapeutics LLC
Neuroscience Trials Australia

Completed

A Dose Ranging Pilot Study for Intracerebroventricular (ICV) Delivery of Valproate in Subjects With Temporal Seizures

Epilepsy

Australia
Sage Therapeutics

Completed

Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus (SRSE)

Super-refractory Status Epilepticus

United States
Sage Therapeutics

Completed

A Study With SAGE-547 for Super-Refractory Status Epilepticus

Super-Refractory Status Epilepticus

United States, Austria, Canada, Denmark, Estonia, Finland, France, Germany, Hungary, Israel, Italy, Netherlands, Serbia, Spain, Sweden, United Kingdom
Eisai Korea Inc.

Completed

Trial Evaluating the Efficacy and Safety of Perampanel Added to Monotherapy in Participants With Partial Onset Seizures With or Without Secondary Generalization

Epilepsy

Korea, Republic of
Banaras Hindu University
Institute of Medical Sciences of the Banaras Hindu University (BHU),India

Completed

Levetiracetam Versus Sodium Valproate in Children With Refractory Generalized Convulsive Status Epilepticus

Grand Mal Status Epilepticus
University Hospital, Basel, Switzerland
Clinical Trial Unit, University Hospital Basel, Switzerland; University Hospital...

Withdrawn

Intravenous Levetiracetam as First-line Anticonvulsive Treatment in Patients With Non-convulsive Status Epilepticus (Keppra)

Status Epilepticus, Non-Convulsive

Switzerland
University Medical Centre Ljubljana
University of Ljubljana School of Medicine, Slovenia

Unknown

Viral Respiratory and Gastrointestinal Infections in Children Under 6 Years of Age

Gastroenteritis | Bronchiolitis | Convulsion, Febrile

Slovenia
GlaxoSmithKline

Terminated

An Open Label Study to Evaluate the Effects of Ezogabine/Retigabine Added to Existing Anti-epileptic Drug(s) on Urinary Voiding Function in Subjects With Partial Onset Seizures

Epilepsy

United States, France, Poland
UCB Pharma

Terminated

A Double-blind, Randomized Conversion to Monotherapy Study to Evaluate the Efficacy and Safety of Brivaracetam in Subjects (≥ 16 to 75 Years Old) With Partial Onset Seizures

Epilepsy

United States, France, Germany, Spain, Hungary, Italy
Sage Therapeutics

No longer available

An Open Label, Expanded Access Protocol With SAGE-547 for Super-Refractory Status Epilepticus

Super-Refractory Status Epilepticus
Eisai Inc.

Completed

A Study for Evaluating the Efficacy and Safety of Zonisamide and Lamotrigine (Lamictal) for Subjects With Refractory Simple Partial, Complex Partial or Partial With Secondary Generalized Seizures

Epilepsy

China
Duke University

Recruiting

Oxygen Toxicity: Mechanisms in Humans

Seizures | Hypercapnia | Oxygen Toxicity

United States
University of Virginia
Medical University of South Carolina; National Institute of Neurological Disorders... and other collaborators

Completed

Established Status Epilepticus Treatment Trial (ESETT)

Benzodiazepine Refractory Status Epilepticus

United States
Xuanwu Hospital, Beijing

Unknown

Phenobarbital Versus Valproate for Generalized Convulsive Status Epilepticus

Generalized Convulsive Status Epilepticus

China
UCB Pharma

Terminated

A Double-blind, Randomized Conversion to Monotherapy Study to Evaluate the Efficacy and Safety of Brivaracetam in Subjects (≥ 16 to 75 Years Old) With Partial Onset Seizures

Epilepsy

United States, Belgium, Canada, Germany, Sweden, Czechia, Australia
Le Bonheur Children's Hospital

Completed

Pediatric Seizure Movement Bed Alarm (PedsBedAlarm)

Epilepsy | Sleep | Seizures

United States
Assistance Publique - Hôpitaux de Paris

Completed

Study of Antiepileptic Drug in Generalised Convulsive Status Epilepticus (SAMU-KEPPRA)

Status; Epilepticus, Tonic-clonic

France
Norwegian University of Science and Technology
St. Olavs Hospital

Recruiting

Predisposing Factors for Post-stroke Epilepsy (PRESTEP)

Stroke | Epilepsy | Seizures | Post Stroke Epilepsy

Norway
Ain Shams University

Completed

Intranasal vs Buccal vs Intramuscular Midazolam for the Home and Emergency Treatment of Acute Seizures

Convulsions

Egypt
KEMRI-Wellcome Trust Collaborative Research Program
University of Oxford; African Population and Health Research Center

Enrolling by invitation

Evaluation Of A Mobile Messaging Service In Improving Adherence Of Anti-Seizure Medications

Epilepsy | Treatment Adherence

Kenya
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Open-Label Extension Study Of Safety And Tolerability Of Pregabalin In Pediatric Patients With Partial-Onset Seizures

Epilepsies, Partial

United States, Mexico, Korea, Republic of
Supernus Pharmaceuticals, Inc.
Parexel

Completed

Evaluation of Efficacy and Safety of OXC XR as Adjunctive Therapy for Partial Seizures (PROSPER1)

Epilepsies, Partial

United States, Poland, Mexico, Bulgaria, Romania, Canada, Russian Federation, Croatia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Effectiveness and Safety of Topiramate Monotherapy in Patients With Recently Diagnosed Partial-Onset Seizure

Epilepsy | Seizures | Epilepsies, Partial
UCB Biopharma S.P.R.L.

Terminated

Study to Evaluate the Long-term Safety and Tolerability of USL261 in Patients With Seizure Clusters

Epilepsy

United States, Australia, Hungary, Israel, Poland, Ukraine, Spain, Canada, Germany, New Zealand
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Safety, Tolerability, and Pharmacokinetic Study of Pregabalin in Pediatric Patients With Partial Onset Seizures

Epilepsies, Partial

United States, Korea, Republic of, Mexico
Soul, Janet , M.D.
National Institute of Neurological Disorders and Stroke (NINDS); Charles H.... and other collaborators

Completed

Pilot Study of Bumetanide for Newborn Seizures

Seizures

United States
UCB Japan Co. Ltd.

Completed

A Long Term Follow up Administration Study of L059 (Levetiracetam) in Epilepsy Patients With Partial Onset Seizures

Epilepsies | Partial

Japan
UCB BIOSCIENCES, Inc.

Completed

Open-Label Extension Study to Assess the Safety and Seizure Frequency Associated With Lacosamide for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy

Epilepsy

United States
Boston Children's Hospital
Lundbeck LLC

Completed

Electrical Status Epilepticus in Sleep: Response of Neuropsychological Deficits and Epileptiform Activity to Clobazam Treatment (ESES-Clobazam)

Electrical Status Epilepticus in Sleep

United States
UCB Japan Co. Ltd.

Completed

A Double-blind Confirmatory Trial of Levetiracetam in Epilepsy Patients With Partial Onset Seizures

Epilepsies, Partial

Japan
UCB Pharma

Withdrawn

A Study to Evaluate the Efficacy and Safety of Seletracetam in Adult Patients With Refractory Partial Onset Seizures

Epilepsies, Partial
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Effectiveness and Safety of Topiramate in the Treatment of Children With Epilepsy

Epilepsy | Seizures | Epilepsies, Partial
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Topiramate in the Treatment of Patients With Epilepsy.

Epilepsy | Seizures | Epilepsies, Partial
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Topiramate in the Treatment of Patients With Difficult to Control Epilepsy

Epilepsy | Seizures | Epilepsies, Partial
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures

Epilepsy | Seizures | Epilepsies, Partial

Clinical Trials on Seizure Disorder

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