Clinical Trials on Severe Adverse Reactions in Russian Federation

Total 71 results

I.M. Sechenov First Moscow State Medical University

Recruiting

Cardiovascular Diagnostic in Assessment of Risk HDS and HCT in Patients With Haemoblasts.

Cardiotoxicity

Russian Federation
Bakulev Scientific Center of Cardiovascular Surgery

Completed

COlchicine in Cardiac Surgery (COCS)

Atrial Fibrillation New Onset | Colchicine Adverse Reaction

Russian Federation
I.M. Sechenov First Moscow State Medical University

Completed

Cardiotoxicity Monitoring With Single-lead Electrocardiogram

Cardiotoxicity

Russian Federation
AstraZeneca

Completed

Observational Prospective Study OPTIMA II - Follow-up (OPTIMAII)

Major Adverse Cardiovascular and Cerebrovascular Events (MACCE)

Russian Federation
POLYSAN Scientific & Technological Pharmaceutical...

Recruiting

Remaxol® in Patients With Drug-induced Liver Injuries During Cancer Chemotherapy

Cancer | Drug Induced Liver Injury

Russian Federation
Gamaleya Research Institute of Epidemiology and...

Completed

Open Study of the Duration of Immunity After Vaccination With GamEvac-Combi

Ebola Hemorrhagic Fever

Russian Federation
Sechenov University
Pirogov Russian National Research Medical University

Recruiting

Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population

Bullous Pemphigoid | Stevens-Johnson Syndrome | Toxic Epidermal Necrolyses | Pemphigus

Russian Federation
Samara State Medical University

Recruiting

Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With AML

Endothelial Dysfunction | Cardiotoxicity | Acute Myeloid Leukemia, Adult

Russian Federation
Moscow State University of Medicine and Dentistry

Recruiting

Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy. (PROMETEY)

Heart Failure | Dilated Cardiomyopathy | Cardiotoxicity

Russian Federation
Gamaleya Research Institute of Epidemiology and...

Completed

Open Study of the Duration of Immunity After Vaccination With GamEvac

Hemorrhagic Fever, Ebola

Russian Federation
Petrovsky National Research Centre of Surgery

Recruiting

Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS) (РМХ vs SS)

Multiple Organ Dysfunction With Severe Endotoxemia

Russian Federation
Gamaleya Research Institute of Epidemiology and...

Unknown

An Open Study of the Safety and Pharmacokinetics of a Drug for the Emergency Prevention of Ebola Virus Disease

Ebola Virus Disease

Russian Federation
Biocad

Completed

An International Multicenter, Randomized, Double-blind, Placebo-Controlled Clinical Study of Efficacy and Safety of Two Dosing Regimens of BCD-085 (JSC BIOCAD, Russia) in Patients With Moderate to Severe Plaque Psoriasis (BCD-085-7)

Moderate to Severe Plaque Psoriasis

Russian Federation
Gamaleya Research Institute of Epidemiology and...
CREMS (Centre de Recherche Epidémiologie, Microbiologie et Soins médicaux )

Completed

International Multicenter Study of the Immunogenicity of Medicinal Product GamEvac-Combi

Ebola Virus Disease | Prevention

Russian Federation, Guinea
Interregional Public Organization, Russian Respiratory...
AstraZeneca Pharmaceuticals" LLC; Limited Liability Company Regional United...

Unknown

Russian Severe Asthma Registry (RSAR)

Severe Asthma

Russian Federation
Federal Research Institute of Pediatric Hematology...

Not yet recruiting

Total Lymphoid Irradiation Pre-HSCT in Severe Congenital Neutropenia

Severe Congenital Neutropenia | GATA2 Deficiency

Russian Federation
Esperion Therapeutics, Inc.
The Cleveland Clinic

Completed

Evaluation of Major Cardiovascular Events in Participants With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or Placebo (CLEAR Outcomes)

Cardiovascular Diseases | Statin Adverse Reaction

Belgium, Germany, United States, Austria, Estonia, Mexico, New Zealand, Spain, Russian Federation, Netherlands, Hungary, Australia, Denmark, South Africa, United Kingdom, Bulgaria, Argentina, Romania, Turkey, Croatia, Serbia, Canada, Lithuan... and more
Blokhin's Russian Cancer Research Center

Recruiting

3D Printed Implants for the Defect Reconstruction in Patients With Chest Wall Tumors

Surgery | Implant Site Reaction | Sarcoma of Bone | Chest Wall Tumor | Tumor of Bone | Chest Wall Sarcoma

Russian Federation
Northern State Medical University

Completed

The Effect pf Goal-directed De-escalation in ARDS on Organ Function and Mortality

ARDS, Human | Sepsis, Severe

Russian Federation
AstraZeneca

Completed

Real World Evidence of Benralizumab in Eosinophilic Severe AsThma in Russia (BEST)

Severe Eosinophilic Asthma

Russian Federation
I.M. Sechenov First Moscow State Medical University

Completed

Prognosis and Course of COVID-19 Infection in Hospitalised Patients

Covid19 | SARS-CoV Infection

Russian Federation
AbbVie (prior sponsor, Abbott)

Completed

An Open-Label, Prospective Study to Assess the Safety and Effectiveness of Adalimumab in Patients With Moderate to Severe Plaque Psoriasis in the Russian Federation

Moderate to Severe Plaque Psoriasis

Russian Federation
Octapharma

Completed

Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Wilate in Previously Treated Paediatric Patients With Severe Haemophilia A

Severe Hemophilia A

Russian Federation, Ukraine
Northern State Medical University

Completed

The Effect of Closed Suction System on the Incidence of Ventilator-associated Pneumonia. (CSS-VAP)

Encephalitis | Seizures | Pancreatic Diseases | Trauma Injury | Severe Traumatic Brain Injury | Abdominal Sepsis

Russian Federation
Novartis

Completed

Efficacy and Safety of the Combination of Aliskiren (300 mg) and Amlodipine (10 mg) Compared to Amlodipine (10 mg) Monotherapy in Patients With Moderate to Severe Hypertension

Moderate to Severe Hypertension

Russian Federation, Romania, Singapore, Spain, Germany, Philippines
I.M. Sechenov First Moscow State Medical University

Completed

Direct and Cross Effects of Adaptation to Systemic Hyperthermia: Impact on Quality of Life, Neurohormonal and Psychophysiological Human Status

Quality of Life | Metabolic Disturbance | Exercise Tolerance | Hypoxia, Altitude

Russian Federation
Saint Petersburg State University, Russia

Not yet recruiting

Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients

Ischemic Heart Disease | Mitral Insufficiency | Aortic Stenosis, Severe | Mitral Stenosis | Aortic Insufficiency | Ascending Aortic Aneurysm | Mitral Stenosis With Insufficiency | Tricuspid Insufficiency

Russian Federation
St. Petersburg Research Institute of Vaccines and...

Recruiting

Tolerability, Safety and Immunogenicity Trial of the Flu-M Tetra Vaccine in Children

Vaccine Reaction | Influenza | Influenza, Human | Influenza Viral Infections

Russian Federation
Meshalkin Research Institute of Pathology of Circulation

Completed

Surgical Prevention of Atrial Fibrillation in Patients With Rheumatic Mitral Valve Lesion and Left Atrium Enlargement

Atrial Fibrillation | Rheumatic Heart Disease

Russian Federation
R-Pharm International, LLC
Atlant Clinical LLC; Center for Pharmaceutical Analytics LLC; Unimed Laboratories... and other collaborators

Recruiting

Safety and Efficacy of RPH-104 Used to Prevent Recurrent Fever Attacks in Adult Patients With Colchicine Resistant or Colchicine Intolerant Familial Mediterranean Fever

Familial Mediterranean Fever | FMF

Armenia, Georgia, Russian Federation
Masaryk University

Recruiting

COVID-19 Vaccines Safety Tracking (CoVaST)

Adverse Reaction to Vaccine | COVID19 Vaccine

Poland, Canada, United States, Croatia, Czechia, Estonia, Ethiopia, Germany, Ghana, Mexico, Portugal, Russian Federation, Serbia, Slovenia
Federal State Budgetary Organization, Federal Center...

Completed

AESCULAP® Plasmafit® Cementless Acetabular System With Vitelene® Vitamin E Stabilized Highly Crosslinked Polyethylene

Osteoarthritis, Hip | Degenerative Osteoarthritis | Rheumatic Arthritis

Russian Federation
St. Petersburg Research Institute of Vaccines and...

Completed

Tolerability, Safety and Immunogenicity Trial of the Flu-M Quadro, Tetravalent Inactivated Split Influenza Vaccine

Vaccine Reaction | Influenza | Influenza, Human | Vaccination; Infection | Influenza Viral Infections

Russian Federation
Bayer

Completed

Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Febrile Upper Respiratory Tract Infections Suspected to be of Viral Origin

Respiratory Tract Infections | Fever

Ukraine, Russian Federation
R-Pharm International, LLC
R-Pharm; Atlant Clinical LLC; Unimed Laboratories CJSC; Data Management 365; Center...

Recruiting

Efficacy and Safety of RPH-104 for Resolution and Prevention of Recurring Attacks in Adult Subjects With Familial Mediterranean Fever With Resistance to or Intolerance of Colchicine

Familial Mediterranean Fever | FMF

Armenia, Georgia, Russian Federation
Novartis Pharmaceuticals

Recruiting

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis (SPARROW)

Moderate-to-severe Plaque Psoriasis

Russian Federation
R-Pharm International, LLC
Data Management 365; K-Research, LLC

Completed

Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19)

COVID-19

Russian Federation
NPO Petrovax

Completed

A Study to Prove Non-inferior Immunogenicity of Grippol Quadrivalent Compared to Grippol Plus

Vaccine Reaction | Influenza | Influenza, Human | Influenza A | Acute Respiratory Infection | Influenza Type B | Flu | Influenza A H3N2 | Influenza A H1N1 | Flu, Human | Influenza Epidemic

Russian Federation
Chiesi Farmaceutici S.p.A.

Completed

Phase II Study to Evaluate the Cardiac Safety of 2 Doses of CHF5993 Both Combined With CHF1535 BID Versus CHF1535 BID in Patients With Moderate to Severe COPD (CARSAF)

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Bulgaria, Germany, Hungary, Poland, Russian Federation, United Kingdom
Octapharma

Completed

Clinical Study to Investigate the PK, Efficacy, and Safety of Wilate in Patients With Severe Hemophilia A

Severe Hemophilia A

Bulgaria, Poland, Hungary, Romania, Russian Federation
Ipsen

Terminated

Study to Assess the Efficacy and Safety of Different Doses of BIM 23A760 in Patients With Carcinoid Syndrome (CAMPANULA)

Carcinoid Syndrome

Spain, Belgium, Ireland, Czechia, Israel, France, United Kingdom, Latvia, Germany, Russian Federation, Slovakia, Italy, Netherlands, Finland, Austria, Poland, Sweden, Ukraine
Ipsen

Completed

An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome (ELECT)

Carcinoid Syndrome

United States, Turkey, Brazil, India, Ukraine, South Africa, Czechia, Latvia, Poland, Russian Federation, Serbia
Drug Induced Liver Disease Study Group
Unimed Scientific Inc.

Completed

A Retrospective Study on Drug Induced Liver Injury in China (DILI-R)

Drug-Induced Liver Injury

China
Novartis Pharmaceuticals

Completed

Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis

Moderate to Severe Chronic Plaque-type Psoriasis

Belgium, Spain, Russian Federation, Germany, United States, Czechia, Peru, Poland, Estonia
AstraZeneca

Completed

Epanova® for Lowering Very High Triglycerides (EVOLVE)

Severe Hypertriglyceridemia

United States, Hungary, India, Russian Federation, Denmark, Ukraine, Netherlands
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Canakinumab in Patients With Hereditary Periodic Fevers

Hereditary Periodic Fevers

Belgium, Italy, Japan, Russian Federation, Turkey, Spain, Germany, United Kingdom, France, United States, Ireland, Israel, Canada, Hungary, Netherlands, Switzerland
Novartis Pharmaceuticals

Completed

Pediatric Study in Children and Adolescents With Severe Plaque Psoriasis

Chronic Severe Plaque-type Psoriasis

Belgium, Italy, Egypt, France, Hungary, Russian Federation, Germany, Israel, Spain, Japan, Estonia, United Kingdom, Poland, Colombia, United States, Latvia, Guatemala, Romania, Switzerland
Novartis Pharmaceuticals

Completed

Study of Safety, Tolerability, and Efficacy of Secukinumab in Subjects With Moderate to Severe Palmoplantar Psoriasis (GESTURE)

Moderate to Severe Palmoplantar Psoriasis

Belgium, United States, Hungary, Russian Federation, Turkey, Australia, Israel, Netherlands, Portugal, Spain, United Kingdom, Norway, Slovakia, Canada, Finland
InflaRx GmbH

Completed

Randomized, Controlled Study of IFX-1 in Patients With Severe COVID-19 Pneumonia (PANAMO)

Severe COVID-19 Pneumonia

Belgium, Brazil, France, Germany, Mexico, Netherlands, Peru, Russian Federation, South Africa
UCB Biopharma SRL

Completed

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis (BE SURE)

Moderate to Severe Plaque Psoriasis | Chronic Plaque Psoriasis

United States, Australia, Canada, Germany, Hungary, Korea, Republic of, Poland, Russian Federation, Taiwan

Clinical Trials on Severe Adverse Reactions in Russian Federation

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CROs in Austria

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