Clinical Trials on Severe Bacterial Infections in Czechia

Total 710 results

MB PHARMA s.r.o.

Recruiting

Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG®

Bacterial Infections | Surgical Wound Infection | Surgical Site Infection | Staphylococcus Aureus Infection | Pseudomonas Aeruginosa Infection

Czechia
Charles University, Czech Republic

Active, not recruiting

ICIS in Burn Patients Compared to Other Inflammatory Markers (ICARUS)

Inflammation | Burns | Infection, Bacterial

Czechia
Thomayer University Hospital
Charles University, Czech Republic

Recruiting

Cytometric Immunodiagnostics of Latent Tuberculosis Infection (LTBI)

BCG Vaccination Reaction | LTBI | TB

Czechia
Value Outcomes Ltd.
Matuzalem.com-cz, s.r.o.

Completed

Vaginal Ovule With Flavonoid Tea Extract for the Correction of Imbalance in the Vaginal Environment (MAT072017)

Vaginosis, Bacterial | Vaginal Flora Imbalance

Czechia
Charles University, Czech Republic
Faculty Hospital Kralovske Vinohrady; Donatio Intensivistam Endowment Fund

Recruiting

Faecal Bacteriotherapy for Postantibiotic Diarrhoea in Critically Ill Patients (FEBATRICE)

Diarrhea Caused by Drug | Clostridium Difficile Infections

Czechia
Charles University, Czech Republic
University Hospital, Motol; Bulovka Hospital

Recruiting

T2MR PCR Detection of ESKAPE Pathogens in Patients With Pyogenic Spondylodiscitis and Infective Endocarditis

Endocarditis, Bacterial | Osteomyelitis; Vertebra

Czechia
GlaxoSmithKline

Completed

Study to Assess Potential Immune Interference When GlaxoSmithKline (GSK) Biologicals' MenABCWY Vaccine is Administered to Healthy Subjects Aged 10-25 Years

Meningitis, Meningococcal

Czechia
Novartis
Novartis Vaccines

Completed

A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults

Japanese Encephalitis | Rabies | Yellow Fever | Meningococcal Disease | Typhoid | Meningococcal Meningitis

Czech Republic, Germany
Bulovka Hospital
Örebro University, Sweden

Completed

Cefixime Plus Doxycycline Compared to Ceftriaxone Plus Azithromycin for Treatment of Gonorrhoea

Gonorrhea

Czechia
GlaxoSmithKline
Novartis Vaccines

Completed

Safety and Immunogenicity of the Liquid Formulation of Group B Streptococcus Trivalent Vaccine and of the Lyophilized Formulation of Group B Streptococcus Trivalent Vaccine

Streptococcal Infections | Infections, Streptococcal

United States, Belgium, Czechia
Medinova AG

Terminated

Comparison of Dequalinium Chloride (Fluomizin) vs Oral Metronidazole for the Treatment of Bacterial Vaginosis

Vaginal Diseases | Bacterial Vaginosis | Vaginal Infection

Slovakia, Czechia, Poland
Summit Therapeutics

Completed

A Study of Ridinilazole (SMT19969) Compared With Fidaxomicin for the Treatment of Clostridium Difficile Infection (CDI)

Clostridium Difficile Infection

United Kingdom, United States, Czechia
Brno University Hospital

Recruiting

Corticosteroids in Severe COVID-19(ASAP-C Study) (ASAP-C)

Severe COVID-19

Czechia
B. Braun Melsungen AG

Completed

Rate of Catheter Colonization and Risk of Bloodstream Infection During Use of Two Different Central Venous Catheters (CVC)

Catheter Related Bloodstream Infection | Bacteriaemia

Czech Republic
Brno University Hospital

Unknown

Early Identification of Sepsis in Children

Sepsis | Shock, Septic | SIRS | Sepsis, Severe

Czechia
University Hospital Ostrava

Completed

Midline Programme - Vascular Nursing Team

Inflammation | Local; Infection

Czechia
GlaxoSmithKline

Completed

Long-term Follow-up Study of Children Previously Primed With GSK Pneumococcal Vaccine (GSK1024850A) and of Unprimed Children

Infections, Streptococcal

Czechia
Actelion

Terminated

Comparison of Cadazolid Versus Vancomycin in Children With Clostridium Difficile-associated Diarrhea (CDAD)

Clostridium Difficile Infection

United States, Belgium, Canada, Czechia, Hungary, Italy, Poland, Romania, Spain
UMC Utrecht
MedImmune LLC

Completed

Advanced Understanding of Staphylococcus Aureus Infections in Europe - Surgical Site Infections (ASPIRE-SSI)

Staphylococcus Aureus | Surgical Wound Infection

United Kingdom, Netherlands, Spain, Czechia, Serbia, Belgium, France, Estonia, Italy, Romania
Brno University Hospital
European Society of Intensive Care Medicine; European Society of Anaesthesiology...

Completed

Corticosteroids in Severe COVID-19 (ASAP-ESICM/ESAIC Study) (ASAPESICMESAIC)

Severe COVID-19

Czechia
Pfizer

Recruiting

Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections

Gram-negative Bacterial Infections

Spain, Taiwan, United States, Hungary, India, China, Turkey, Greece, Czechia
GlaxoSmithKline

Completed

Safety & Immunogenicity of Pneumococcal Vaccine 2189242A in Children Aged 12-23 Months at the Time of First Vaccination

Infections, Streptococcal

Czechia
Impatients N.V. trading as myTomorrows
Inmunotek S.L.

No longer available

Expanded Access Program Using Uromune for Patients With Recurrent Urinary Tract Infections (rUTI)

Urinary Tract Infections | Bladder Infection | Recurrent Urinary Tract Infection | Urinary Tract Infection Bacterial | Chronic Urinary Tract Infection

Czechia, Denmark, Serbia, France, Germany, Turkey, Belgium, Finland, Luxembourg, Netherlands, Norway, Romania, Slovakia, Slovenia, Sweden
Lyme Diagnostics Ltd.
Pharmahungary Group

Completed

Performance Evaluation of the DualDur In Vitro Diagnostic System in the Diagnosis of Lyme Borreliosis

Lyme Borreliosis

Austria, Czechia, Germany, Hungary, Poland, Slovakia
GlaxoSmithKline

Completed

Prophylactic Antipyretic Treatment in Children Receiving Booster Dose of Pneumococcal Conjugate Vaccine GSK1024850A

Infections, Streptococcal

Czechia
Trius Therapeutics LLC

Completed

TR-701 FA vs. Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections. (ABSSSI)

Skin and Subcutaneous Tissue Bacterial Infections

United States, Argentina, Brazil, Canada, Czechia, Germany, Hungary, Latvia, Peru, Slovakia, Ukraine
Valneva Austria GmbH

Completed

Confirmatory Phase II/III Study Assessing Efficacy, Immunogenicity and Safety of IC43

Pseudomonas Aeruginosa Infection

Spain, Germany, Belgium, Austria, Czech Republic, Hungary
Pfizer

Completed

Duration of hSBA Response After a Primary Series of Bivalent rLP2086 Followed by a Booster Dose

Meningococcal Infection

United States, Finland, Czechia, Sweden, Denmark, Germany
Blueberry Therapeutics
IQVIA Biotech

Completed

A Trial Involving Treatment of BB2603 in Subjects With Distal Subungual Onychomycosis of the Toenail

Fungal Infection | Distal Subungual Onychomycosis | Fungus, Nail

Poland, Germany, Czechia
GlaxoSmithKline

Completed

Comparison of GlaxoSmithKline (GSK)134612 in Subjects With Increased Risk for Meningococcal Disease Versus Healthy Subjects

Infections, Meningococcal

United States, Czechia
University Hospital Ostrava
University Hospital, Motol

Recruiting

Invasive Candidiasis in Critical Care

Invasive Candidiasis

Czechia
University Hospital Ostrava

Completed

Control of Fever in Septic Patients (COVERSEP)

Sepsis | Septic Shock | Severe Sepsis

Czechia
Summit Therapeutics

Completed

To Compare Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile Infection (Ri-CoDIFy 2)

Clostridioides Difficile Infection

United States, Spain, France, Canada, Belgium, Israel, Chile, Belarus, Latvia, Germany, Romania, Lithuania, Mexico, Czechia, Estonia, Georgia, Peru
Brno University Hospital
St. Anne's University Hospital Brno, Czech Republic

Recruiting

The Diagnosis of Superinfections in Mechanically Ventilated Covid-19 Patients (SUPER-BAL)

COVID-19 Pneumonia | ARDS, Human | Superinfection

Czechia
Merck Sharp & Dohme LLC

Completed

Bezlotoxumab (MK-6072) Versus Placebo in Children With Clostridium Difficile Infection (CDI) (MK-6072-001) (MODIFY III)

Clostridium Difficile Infection

United States, Argentina, Brazil, Colombia, Czechia, Germany, Hungary, Malaysia, Mexico, Norway, Poland, Portugal, Romania, South Africa, Spain, Sweden, United Kingdom
Boehringer Ingelheim

Completed

A Study Investigating Long-term Treatment With Spesolimab in People With a Skin Disease Called Hidradenitis Suppurativa Who Completed a Previous Clinical Trial

Hidradenitis Suppurativa

Australia, United States, Germany, Netherlands, Italy, Canada, Czechia, France, Norway, Poland, Spain
Phathom Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection

Helicobacter Pylori Infection

United States, Hungary, Poland, Bulgaria, United Kingdom, Czechia
University Hospital Ostrava
Municipal Hospital Ostrava; University Hospital Olomouc; University of Ostrava; Public Health Institute Ostrava and other collaborators

Recruiting

Early Diagnosis of Invasive Lung Aspergillosis

Invasive Pulmonary Aspergillosis | Respiratory Infection

Czechia
Boehringer Ingelheim

Completed

A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Hidradenitis Suppurativa

Hidradenitis Suppurativa

Norway, United States, Australia, Germany, Netherlands, Italy, Canada, Czechia, France, Poland, Spain, Belgium
Astellas Pharma Europe Ltd.
Merck Sharp & Dohme LLC

Completed

A Phase IIIB/IV Study to Compare the Efficacy of Vancomycin Therapy to Extended Duration of Fidaxomicin Therapy in the Clinical Cure of Clostridium Difficile Infection (CDI) in an Older Population (EXTEND)

Clostridium Difficile

Greece, Spain, Russian Federation, Denmark, Austria, Belgium, Croatia, Czechia, Finland, France, Germany, Hungary, Ireland, Italy, Poland, Portugal, Romania, Slovenia, Sweden, Switzerland, Turkey, United Kingdom
University Hospital Ostrava

Recruiting

Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients

Arterial Hypertension

Czechia
Pfizer

Completed

Clostridium Difficile Vaccine Efficacy Trial (Clover)

Clostridium Difficile Infection

United States, Spain, Belgium, Taiwan, Japan, Portugal, Colombia, Korea, Republic of, Poland, Australia, Germany, Canada, Argentina, Bulgaria, Chile, Czechia, Finland, France, Hungary, Peru, Slovakia, Sweden, United Kingdom
Actelion

Completed

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea

Clostridium Difficile Infection

United States, Belgium, Israel, Argentina, Brazil, Canada, Chile, Croatia, Czechia, Greece, Hungary, Korea, Republic of, Romania, Slovakia
Institute for Clinical and Experimental Medicine

Not yet recruiting

Use of Wearables to Detect Infections in Kidney Transplant Recipients (RENALERT)

Kidney Transplant Infection

Czechia
University Hospital Ostrava

Recruiting

Diagnostics of Mycotic Sinusitis in ENT Patients

Fungal Sinusitis

Czechia
Polichem S.A.

Completed

Study to Evaluate the Efficacy and Safety of P-3058 10% Nail Solution in the Treatment of Toenail Onychomycosis

Onychomycosis

Belgium, Bulgaria, Czechia, Germany, Greece, Hungary, Iceland, Latvia, Lithuania, Poland, Russian Federation, Slovakia, Sweden
University Hospital Hradec Kralove

Recruiting

Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients

COVID-19 Respiratory Infection

Czechia
University Hospital Ostrava

Completed

Recurrent Respiratory Papillomatosis and Extraesophageal Reflux

Recurrent Respiratory Papillomatosis | Extra Oesophageal Reflux | Laryngeal Cyst

Czechia
Novartis Vaccines

Completed

One Year Antibody Persistence After a Fourth Dose Boost or Two Catch-Up Doses of Novartis Meningococcal B Recombinant Vaccine Administered Starting From 12 Months of Age and Response to a Third Dose Boost or Two Catch-Up Doses Starting at 24 Months of Age

Meningococcal Disease

Finland, Czech Republic
GlaxoSmithKline

Completed

Safety & Immunogenicity of Pneumococcal Vaccine 2189242A Co-administered With DTPa-HBV-IPV/Hib in Healthy Infants

Infections, Streptococcal

Germany, Czechia, Sweden, Poland

Clinical Trials on Severe Bacterial Infections in Czechia

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