Clinical Trials on Severe Combined Immunodeficiency in Germany

Total 384 results

Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Immunogenicity of Vaxelis™ in Children Previously Vaccinated With Vaxelis™ or Hexyon™ (V419-016)

Vaccines, Combined | Hexavalent Vaccine

Germany, Italy, Spain
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and Children

Dengue Fever | Dengue Hemorrhagic Fever | Dengue Shock Syndrome

Puerto Rico
Octapharma

Completed

A Study to Compare Quality of Life and Satisfaction in Primary Immunodeficient Patients Treated With Subcutaneous Injections of Gammanorm® 165 mg/mL Administered With Two Different Delivery Devices: Injections Using Pump or Rapid Push

Primary Immunodeficiency

United Kingdom, Australia, Germany, Italy
Universitätsklinikum Hamburg-Eppendorf
University Hospital, Geneva; Wellcome Trust; KEMRI-Wellcome Trust Collaborative... and other collaborators

Completed

Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine (rVSVΔG-ZEBOV-GP)

Hemorrhagic Fever, Ebola

Germany
Technische Universität Dresden
GWT-TUD GmbH

Completed

Assessment of Immunoglobulins (IgG) in a Long-term Non-interventional Study (SIGNS)

Primary Immunodeficiency (PID) | Secondary Immunodeficiency (SID) | Neurological Autoimmune Disease

Germany
U.S. Army Medical Research and Development Command

Recruiting

Intravenous Ribavirin Protocol to Treat Individuals With Viral Hemorrhagic Fever

Viral Hemorrhagic Fever

Germany
Allergan

Completed

Post-Market Study of JUVÉDERM VOLIFT™ With Lidocaine for the Correction of Nasolabial Folds

Moderate to Severe Nasolabial Folds

Germany, Netherlands
Tibotec Pharmaceuticals, Ireland

Completed

A Study to Determine the Antiviral Activity of TMC310911 When Administered With Ritonavir in Treatment-Naive Human Immunodeficiency Virus - Type 1 (HIV-1) Infected Patients

Human Immunodeficiency Virus Type 1

Germany
University of Rostock

Completed

Extracorporeal Immune Support System (EISS) for the Treatment of Septic Patients (EISS-1)

Severe Sepsis and Septic Shock

Germany
U.S. Army Medical Research and Development Command
Bausch Health Americas, Inc.

Withdrawn

Treatment of Viral Hemorrhagic Fevers With Intravenous Ribavirin in Military Treatment Facilities

Crimean-Congo Hemorrhagic Fever | Lassa Fever

Germany
U.S. Army Medical Research and Development Command

Withdrawn

Ribavirin for Hemorrhagic Fever With Renal Syndrome in Germany (HFRS)

Hemorrhagic Fever With Renal Syndrome

Germany
Klinikum Emden
Universitätsklinikum Hamburg-Eppendorf; Kantonsspital Baden; Kantonsspital Münsterlingen

Completed

Evaluating a CytoSorb Score in Septic Shock (ECSISS)

Severe Sepsis With Septic Shock

Germany
Johann Wolfgang Goethe University Hospital

Completed

Maternal-fetal CD4 Microchimerism in HiV Exposed Newborns After Spontaneous Delivery and Cesarean Section

Human Immunodeficiency Virus

Germany
Christoph Königs
Roche Pharma AG; Chugai Pharma Germany GmbH

Recruiting

Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab (NAVIGATE)

Severe Hemophilia A | Severe Hemophilia A With Inhibitor | Severe Hemophilia A Without Inhibitor

Germany
Abbott

Completed

Long-term Effectiveness and Safety in Hepatitis-co-infected Patients

Human Immunodeficiency Virus-Infection

Germany
University Hospital Schleswig-Holstein
Medical Clinic III; Dezernat Apotheke

Completed

Determining Drug Levels of Beta-lactam Antibiotics in Severe Burned Patients (MSBV)

Intensive Care | Antibiotics | Severe Burn

Germany
CSL Behring

Completed

Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (EU Extension Study)

Primary Immunodeficiency (PID)

Poland, Germany, France, Romania, Spain, Sweden, Switzerland, United Kingdom
Klinikum St. Georg gGmbH

Completed

Balanced Volume Replacement Therapy With Ringer's Acetate Solution in Burn Injury (VoLTRAB)

Severe Burn Injury

Germany
Helios Klinik Gotha/Ohrdruf
Helios Klinikum Erfurt

Not yet recruiting

Outcomes of Patient Blood Management in Severely Anemic Patients

Severe Anemia

Germany
University Hospital Freiburg

Recruiting

Prediction of Portal Hypertension in Patients With CVID (CVID-pHT) (CVID-pHT)

Common Variable Immunodeficiency | Non-Cirrhotic Portal Hypertension

Germany
CSL Behring

Completed

Efficacy and Safety of Vivaglobin® in Previously Untreated Patients With Primary Immunodeficiency

Common Variable Immunodeficiency | Agammaglobulinemia

Canada, Germany, Italy, Spain
Ipsen

Completed

Efficacy and Safety of Clostridium Botulinum Toxin Type A to Improve Appearance of Moderate to Severe Glabellar Lines (BTX-A-HAC NG)

Moderate to Severe Glabellar Lines

France, Germany
Baxalta now part of Shire

Completed

Immune Globulin Subcutaenous (Human), 20%

Primary Immunodeficiency Diseases (PID)

Germany, Austria, Hungary, Sweden, United Kingdom
University of Hohenheim

Completed

Effect of Protein Supplementation After Bariatric Surgery (EPEAB)

Protein Malnutrition

Germany
Cardioangiologisches Centrum Bethanien
Goethe University; Ruhr University of Bochum; Technische Universität Dresden; University... and other collaborators

Completed

Reversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists (RADOA)

Urgent Surgery | Severe Bleeding

Germany
Charite University, Berlin, Germany
German Research Foundation; adexter GmbH

Completed

Immunoadsorption of LPS, C5a and IL-6 in Severe Sepsis and Septic Shock (ISASS-1)

Septicemia

Germany
University of Cologne

Completed

CD4 Cell Recovery in HIV-1 Patients Comparing 2 Treatment Regimes

HIV Infections | Acquired Immunodeficiency Syndrome

Germany
Novartis Pharmaceuticals

Completed

Study of Efficacy of CDZ173 in Patients With APDS/PASLI

Common Variable Immunodeficiency (CVID), APDS / PASLI

Germany, Russian Federation, Ireland, Italy, United Kingdom, Belarus, Netherlands, Czechia, United States
GWT-TUD GmbH

Completed

Facilitated Immunoglobulin Administration Registry and Outcomes Study (FIGARO) (FIGARO)

Primary Immunodeficiency | Secondary Immune Deficiency

Germany, Italy, France
AbbVie (prior sponsor, Abbott)

Completed

Kaletra: Therapy With Double Protease Inhibitors

Human Immunodeficiency Virus

Germany
Merz Aesthetics GmbH
Merz Pharmaceuticals GmbH

Completed

Study to Investigate the Safety and Duration of Effect of Different Botulinum Toxin A (NT 201) Dose Groups Following the Treatment of Glabellar Frown Lines

Moderate to Severe Glabellar Frown Lines

United States, Germany
University of Luebeck
University of Bern; University of Hamburg-Eppendorf; Björn Meyer, Gaia AG, Hamburg...

Completed

Effectiveness of Internet-based Depression Treatment (EVIDENT) in Severe Depression

Severe Depressive Symptoms

Germany, Switzerland
German Center for Neurodegenerative Diseases (DZNE)
University Hospital, Bonn

Unknown

Long-term Cognitive and Cerebral Changes in Sepsis Survivors and Their Predictors (BonSEP)

Severe Sepsis With Septic Shock | Severe Sepsis Without Septic Shock

Germany
B. Braun Melsungen AG
CeGaT GmbH

Completed

Differences in Exhaled Breath by Using Ion Mobility Spectrometry (IMS) in Subjects Tested for SARS-CoV-2 Infection (COVID-19 Disease)

Covid19 | SARS (Severe Acute Respiratory Syndrome)

Germany
ViiV Healthcare
GlaxoSmithKline

Terminated

Dose-finding Study of GSK2248761 in Antiretroviral Therapy-Naive Subjects (SIGNET) (SIGNET)

Infection, Human Immunodeficiency Virus

Spain, France, Germany
Klinikum St. Georg gGmbH
University of Halle Medical Faculty

Terminated

Alterations of Immunologic Mediators During Severe Sepsis (LAVISS_01)

Severe Sepsis

Germany
Ipsen

Terminated

Study to Evaluate the Safety and Efficacy of IPN59011 in Improving the Appearance of Moderate to Severe Upper Facial Lines. (LONG-SET)

Moderate Upper Facial Lines | Severe Upper Facial Lines

Germany
Artcline GmbH
ZKS Jena

Recruiting

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow up (ReActIF- LTO)

Severe Sepsis

Germany
Mundipharma Research GmbH & Co KG

Completed

A Study to Explore the Influence of Two Opioid Pain Medications on Bacterial Composition in the Gut and Other Gastrointestinal Aspects

Severe Chronic Pain

Germany
Clara Lehmann
German Federal Ministry of Education and Research

Completed

Gut Associated Lymphatic Tissue (GALT) in HIV (Human Immunodeficiency Virus)- Infected Patients

HIV Infection

Germany
Sandoz
Sandoz GmbH

Terminated

Immunogenicity, Safety, and Efficacy of Zarzio®/Filgrastim HEXAL® in Patients With Severe Chronic Neutropenia

Severe Chronic Neutropenia

Germany, Sweden
Grifols Therapeutics LLC

Completed

Efficacy, Pharmacokinetics, Safety, and Tolerability of IGSC 20% in Subjects With Primary Immunodeficiency

Primary Immunodeficiency

Spain, France, Germany, United Kingdom, Australia, Czechia, Hungary, Poland, Sweden
Max-Planck-Institute of Psychiatry

Completed

Feasibility of a Novel Process-based Treatment for Patients With Psychosis (PROBAS)

Schizophrenia | Schizoaffective Disorder | Delusional Disorder | Schizotypal Disorder | Brief Psychotic Disorder | Shared Psychotic Disorder | Other Psychotic Disorder Not Due to A Substance or Known Physiological Condition | Unspecified Psychosis Not Due to a Substance or Known Physiological Condition and other conditions

Germany
Diamant Thaci

Withdrawn

Analysis of the Pathogenesis of Itch in Response to Apremilast Therapy in Psoriasis Patients (Itch)

Moderate to Severe Plaque Psoriasis

Germany
ViiV Healthcare
Pfizer

Completed

Pharmacokinetics, Safety And Toleration Of Maraviroc Administered To Subjects With Various Degrees Of Renal Impaired And Normal Renal Function

Human Immunodeficiency Virus (HIV) Infection

Germany
Universitätsklinikum Hamburg-Eppendorf
University of Ulm

Active, not recruiting

HoPe: Home Treatment and Peer Support for Acute Mental Health Crisis (HoPe)

Severe Mental Health Condition With Indication of Hospital Admission

Germany
Charite University, Berlin, Germany

Withdrawn

Drugmonitoring of Antiinfective Drugs in Patients Receiving Continous Veno-venous Hemodiafiltration (ABx-CVVHDF)

Need for Renal Replacement Therapy and Anti-infective Therapy Due to Severe Infection

Germany
ViiV Healthcare
GlaxoSmithKline

Completed

Study to Evaluate a HIV Drug for the Treatment of HIV Infection

HIV Infections | Infection, Human Immunodeficiency Virus

Germany
Universitätsmedizin Mannheim

Completed

Microcirculatory Oxygen Uptake in Sepsis

Sepsis | Septic Shock | Severe Sepsis

Germany
Jena University Hospital

Completed

Risk Stratification With Chest CT to Rule-out Suspected SARS-CoV-2 Infections (SCout)

Severe Acute Respiratory Syndrome Coronavirus 2

Germany

Clinical Trials on Severe Combined Immunodeficiency in Germany

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Hungary

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations