Clinical Trials on Severe Coronary Artery Disease (S-CAD) in United Kingdom

Total 1517 results

Spirocor

Terminated

SPIROCOR Coronary Outcome by Respiratory Stress Examination (SCORE)

Severe Coronary Artery Disease (S-CAD)

United States
CardioDx

Completed

Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern (IMPACT-CARD)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Investigation of a Novel Gene Expression Test (ASGES or Corus CAD) for Diagnosis of Obstructive Coronary Artery Disease (REGISTRY-I)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx
Cardiovascular Research Foundation, New York; Piedmont Heart Institute, Inc...

Completed

Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES) (COMPASS)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Clinical Utility of an Age, Sex, and Gene Expression Score (ASGES or Corus CAD) in African American Patients. (AACU)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx
Mayo Clinic

Completed

Effect of Exercise Stress Testing on Peripheral Gene Expression Using Corus CAD (or ASGES) Diagnostic Test (EXERCISE)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree (PREDICT)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

Understanding Clinician Utilization of Corus CAD (Age/Sex/Gene Expression Score - ASGES) in Clinical Decision Making (UCU-CARD)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Withdrawn

Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making (CU-PCP)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
CardioDx

Completed

A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (or ASGES) in Primary Care Settings (PRESET)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Amount of Drug Levels in Blood and Safety of AZD5718 Formulations in Healthy Volunteers

Coronary Artery Disease (CAD)

United Kingdom
Janssen Scientific Affairs, LLC
HCA Research Institute, LLC

Recruiting

A Study to Assess the Engagement and Usefulness of Care4Today Digital Platform for Disease Management in Coronary Artery Disease (CAD) and/or Peripheral Artery Disease (PAD) Population (IPACE-CVD)

Coronary Artery Disease (CAD) | Peripheral Artery Disease (PAD)

United States
CardioDx

Completed

PCP Use of a Gene Expression Test (Corus CAD or ASGES) in Coronary Artery Disease Diagnosis (IMPACT-PCP)

Cardiovascular Diseases | Coronary Artery Disease | Chest Pain | Angina Pectoris | Coronary Heart Disease | CAD | CHD | CVD

United States
Indiana University
American Heart Association

Completed

Beating the Blues for Your Heart (BtB-Heart)

Depression | Depressive Symptoms | Heart Disease | Coronary Artery Disease (CAD) | Cardiovascular Disease (CVD)

United States
National Institutes of Health Clinical Center (CC)
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gadofosveset Trisodium for Heart Imaging Studies

Coronary Arteriosclerosis | Coronary Artery Disease (CAD) | Obstructive Coronary Artery Disease

United States
Columbia University

Terminated

Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging

Coronary Artery Disease (CAD)

United States
The Medicines Company

Completed

Cangrelor to Clopidogrel or Prasugrel Transition Study (BRIDGE)

Coronary Artery Disease (CAD)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Endothelial Progenitor Cells and Nitric Oxide in Cardiac Rehabilitation Program Participants

Coronary Artery Disease (CAD)

United States
GE Healthcare

Completed

Study in Subjects Suspected of Having CAD Undergoing VISIPAQUE-enhanced CCTA as Part of Their Routine Medical Care

Coronary Artery Disease (CAD)

United States
Lundquist Institute for Biomedical Innovation at...
Heart Test Laboratories, Inc.

Completed

MyoVista Measurements in Patients With Atherosclerosis and CAD

Atherosclerosis | Coronary Artery Disease (CAD)

United States
Columbia University

Completed

Comparison of Orbital Versus Rotational Atherectomy Effects On Coronary Microcirculation in PCI (ORACLE)

Coronary Artery Disease (CAD)

United States
Lantheus Medical Imaging

Withdrawn

A Long-term Follow-up Study to Evaluate the Predictive Value of BMS747158 in Patients Suspected of Coronary Artery Disease (CAD)

Coronary Artery Disease (CAD)

United States
Indiana University
National Institute of Mental Health (NIMH)

Completed

Anti-INFLammatory to Address Mood and Endothelial Dysfunction (INFLAMED) (INFLAMED)

Depression | Depressive Symptoms | Heart Disease | Major Depressive Disorder | Coronary Artery Disease (CAD) | Cardiovascular Disease (CVD)

United States
PolyMedix, Inc.

Terminated

Reversal of Heparin in Patients Undergoing Percutaneous Coronary Intervention (PCI)

Percutaneous Coronary Intervention | Coronary Artery Disease (CAD) | Angioplasty

United States
ECRI bv
AstraZeneca; The Medicines Company; Biosensors International

Completed

GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation

Coronary Artery Disease (CAD)

Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Denmark, France, Germany, Hungary, Italy, Netherlands, Poland, Portugal, Singapore, Spain, Switzerland, United Kingdom
Stanford University
University of California, San Diego; National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery

Coronary Artery Bypass | Computed Tomography | CAD | Atheroscleroses, Coronary

United States
GE Healthcare
Pharmaceutical Product Development, LLC

Completed

An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)

Coronary Artery Disease (CAD)

United States, Germany, Switzerland, Canada, Netherlands, France, Finland
Eli Lilly and Company
Daiichi Sankyo Co., Ltd.

Terminated

Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI) (TRIGGER-PCI)

Coronary Artery Disease (CAD)

United States, Germany
Astellas Pharma Inc

Completed

Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)

Coronary Artery Disease (CAD)

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Assess Regadenoson Administration Following an Inadequate Exercise Stress Test as Compared to Regadenoson Alone for Myocardial Perfusion Imaging (MPI) Using Single Photon Emission Computed Tomography (SPECT) (EXERRT)

Coronary Artery Disease (CAD)

United States, Peru, Argentina, Puerto Rico
Anthera Pharmaceuticals

Completed

PLASMA Trial: A Dose-Response Study of A-002 In Subjects With Stable Coronary Artery Disease (PLASMA)

Coronary Artery Disease (CAD)

United States, Ukraine
Astellas Pharma Inc

Completed

A Study of Regadenoson in Subjects Undergoing Stress Myocardial Perfusion Imaging (MPI) Using Multidetector Computed Tomography (MDCT) Compared to Single Photon Emission Computed Tomography (SPECT)

Coronary Artery Disease (CAD)

United States
Amgen

Completed

Imaging of Coronary Plaques in Participants Treated With Evolocumab

Coronary Artery Disease (CAD)

Australia, Czechia, Italy, United States, Netherlands, Hungary, Germany
Momenta Pharmaceuticals, Inc.

Completed

Evaluation of M118 in Percutaneous Coronary Intervention (EMINENCE) (EMINENCE)

Coronary Artery Disease (CAD)

United States, Canada
Novartis Pharmaceuticals
The Cleveland Clinic

Completed

Safety and Efficacy of Aliskiren on the Progression of Atherosclerosis in Coronary Artery Disease Patients (AQUARIUS)

Coronary Artery Disease (CAD) | Coronary Atherosclerosis

Italy, Spain, Hungary, Australia, United States, Belgium, Canada, Germany, France, Argentina, Poland
Kips Bay Medical, Inc.

Unknown

The eMESH 1 Feasibility Study (eMESH 1)

Atherosclerosis of Autologous Vein Coronary Artery Bypass Graft(s)

United States, United Kingdom, Czech Republic, Netherlands, France, Italy, Switzerland
Abbott Medical Devices

Completed

EXPERT CTO: Evaluation of the XIENCE PRIME™ LL and XIENCE Nano™ Everolimus Eluting Coronary Stent Coronary Stents, Performance, and Technique in Chronic Total Occlusions (EXPERT CTO)

Coronary Artery Disease (CAD) | Chronic Total Occlusion (CTO)

United States
GE Healthcare

Completed

A Study of Flurpiridaz (18F) Injection for PET Imaging for Assessment of MPI Quality Using HPLC and SPE Manufacturing Processes

Ischemic Heart Disease | Coronary Artery Disease (CAD)

United States
Creighton University

Completed

Aspirin Responsiveness in Women With Coronary Artery Disease

CAD

United States
National Heart, Lung, and Blood Institute (NHLBI)
NIH Heart Center at Suburban Hospital

Terminated

Stem Cell Injection to Treat Heart Damage During Open Heart Surgery

Coronary Artery Disease | Ischemic Heart Disease | Heart Disease | Coronary Artery Disease (CAD)

United States
Daniel S. Berman
Astellas Pharma US, Inc.

Completed

Artifact-Free High-Resolution Myocardial Perfusion MRI in Subjects With Abnormal Nuclear Myocardial Perfusion Studies

Coronary Artery Disease | CAD

United States
New York State Psychiatric Institute
National Alliance for Research on Schizophrenia and Depression

Terminated

A Trial of Inflammatory Markers, Depressive Symptoms, and Heart Disease (CHIME)

Depression | Coronary Artery Disease (CAD) | Acute Coronary Syndrome (ACS)

United States
Papworth Hospital NHS Foundation Trust

Completed

Coronary Microcirculatory and Bioresorbable Vascular Scaffolds (EMPIRE-BVS)

Myocardial Ischemia | Angina, Stable | CHD - Coronary Heart Disease

United Kingdom
AstraZeneca

Terminated

Long-Term rIsk, Clinical manaGement and Healthcare Resource Utilization of Stable CAD in Post MI Patients (TIGRIS)

Stable Coronary Artery Disease (CAD), Myocardial Infarction

United States, France, Italy, Spain, Turkey, United Kingdom, Germany, China, Romania, Finland, Netherlands, Norway, Canada, Mexico, Argentina, Australia, Belgium, Denmark, Portugal, Korea, Republic of, India, Japan, Brazil, Colombia, Ve...
Saint Luke's Health System
Gilead Sciences

Completed

Angina Prevalence and Provider Evaluation of Angina Relief (APPEAR)

Stable Coronary Artery Disease CAD

United States
Saint Thomas Health

Withdrawn

RANOLAZINE STUDY: Speckle Tracking Derived Myocardial Strain

Severe Coronary Artery Disease | Ischaemic Myocardial Dysfunction

United States
Derek Richards

Terminated

iCBT for Long-term Conditions in IAPT

Depression | Diabetes | Chronic Pain | Anxiety | COPD | CHD - Coronary Heart Disease

United Kingdom
AstraZeneca

Completed

A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet

High Risk Coronary Artery Disease

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine

Unknown

Prognostic Models for People With Stable Coronary Artery Disease

Stable Coronary Artery Disease

United Kingdom
St George's, University of London
St George's University Hospitals NHS Foundation Trust; Shockwave Medical, Inc.

Unknown

Intravascular Balloon Lithotripsy in Left Main Stem Percutaneous Coronary Intervention

Left Main Coronary Artery Disease | Coronary Artery Calcification

United Kingdom

Clinical Trials on Severe Coronary Artery Disease (S-CAD) in United Kingdom

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