Clinical Trials on Severe Dysplasia of Esophagus in United Kingdom

Total 335 results

Northwell Health
Mayo Clinic; NinePoint Medical

Completed

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)

Barrett's Esophagus Without Dysplasia | Barrett's Esophagus With Dysplasia | Barrett's Esophagus With Low Grade Dysplasia | Barrett's Esophagus With High Grade Dysplasia | Barrett's Esophagus With Dysplasia, Unspecified

United States
Interscope, Inc.

Recruiting

Endorotor Resection In Refractory Barrett's Dysplasia Patients

Barrett's Esophagus With Dysplasia

United States, Sweden, United Kingdom
Massachusetts General Hospital

Enrolling by invitation

Evaluation of Tethered Capsule Endomicroscopy as a Screening Tool for Barrett's Esophagus in the Primary Care Setting

Barrett Esophagus | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia

United States
Mayo Clinic

Recruiting

Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples (SOS4C)

Barrett Esophagus | Esophageal Adenocarcinoma | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia

United States
City of Hope Medical Center

Recruiting

A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma (EMERALD)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Reflux | Barrett Esophagus | Esophageal Adenocarcinoma | Reflux Disease | Barretts Esophagus With High Grade Dysplasia | Barrett Adenocarcinoma | Esophagus Cancer | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia | Esophagus... and other conditions

United States
Lucid Diagnostics, Inc.

Completed

Efficacy of EsoGuard on Samples Collected Using EsoCheck Versus EGD for the Diagnosis of BE (ESOGUARDBE1)

Barrett Esophagus | Esophageal Adenocarcinoma | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia

United States, Spain
Imperial College London
University College London Hospitals; Northern Care Alliance NHS Foundation... and other collaborators

Recruiting

Non-invasive Testing for Early oEesophageal Cancer and Dysplasia (NEED)

Barrett Esophagus | Oesophageal Cancer | Barretts Esophagus With Dysplasia

United Kingdom
Erbe Elektromedizin GmbH
NAMSA; Kansas City Veteran Affairs Medical Center; Erbe USA Incorporated

Terminated

Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation Technique (BURN)

Barrett's Esophagus | High-grade Dysplasia in Barrett Esophagus | Low Grade Dysplasia in Barrett Esophagus

United States
Portsmouth Hospitals NHS Trust
University of Portsmouth

Unknown

Aceto-whitening in the Assessment of Gastrointestinal Neoplasia

Barrett Esophagus | Barrett Adenocarcinoma | Barrett Metaplasia | Barrett Oesophagitis With Dysplasia

United Kingdom
Allegheny Singer Research Institute (also known...
Integra LifeSciences Corporation

Terminated

TECR & ECM Placement for Esophageal High Grade Dysplasia

Barrett Esophagus | High Grade Dysplasia | Esophagus

United States
Medical University of South Carolina

Completed

The Impact of Adjuvant Liquid Alginate on Endoscopic Ablation Therapy of Complicated Barrett's Esophagus

Barretts Esophagus With Dysplasia

United States
The Guthrie Clinic

Active, not recruiting

Cell Marker Predictors in Barrett's Esophagus

Barrett's Esophagus Without Dysplasia

United States
CDx Diagnostics
Icahn School of Medicine at Mount Sinai; NYU Langone Health; University of Kansas... and other collaborators

Completed

WATS3D for the Detection of Esophageal Dysplasia

Barrett Esophagus | Esophagus Adenocarcinoma | Esophageal Dysplasia

United States
CSA Medical, Inc.

Terminated

Study of CryoSpray Ablation of Low Grade or High Grade Dysplasia Within Barrett's Esophagus (ICE)

Barrett's Esophagus | Low Grade Dysplasia | High Grade Dysplasia

United States
The Christie NHS Foundation Trust
AstraZeneca; Cancer Research UK

Unknown

Radiotherapy & Olaparib in COmbination for Carcinoma of the Oesophagus (ROCOCO)

Carcinoma of the Oesophagus

United Kingdom
Massachusetts General Hospital
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy

Barrett Esophagus | Barretts Esophagus With Dysplasia

United States
Lucid Diagnostics, Inc.

Recruiting

CLUE: CLinical Utility Study of EsoGuard (PR-0410)

Barrett Esophagus | Barretts Esophagus With Dysplasia | Esophagus Adenocarcinoma

United States
Mayo Clinic

Completed

Characterization of the Neo-squamous Epithelial Barrier

Barrett's Esophagus With Dysplasia

United States
University of North Carolina, Chapel Hill
Interpace Diagnostics Corporation

Completed

Utility Of Mutational Load As A Predictor For Endoscopic Treatment Response In Barrett's Esophagus

Barretts Esophagus With Dysplasia | Intramucosal Adenocarcinoma

United States
Mayo Clinic

Terminated

Endoscopic Mucosal Resection and Cellular Matrix

Barretts Esophagus With High Grade Dysplasia | Barrett Adenocarcinoma

United States
Roswell Park Cancer Institute

Completed

Study of Photodynamic Therapy (PDT) Using HPPH in Barrett's Esophagus

Barrett's Esophagus | CIS | High Grade Dysplasia

United States
University of Colorado, Denver
Medical University of South Carolina; National Institute of Diabetes and Digestive... and other collaborators

Recruiting

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia (SURVENT)

Barrett Esophagus | Esophageal Adenocarcinoma | Barretts Esophagus With Dysplasia

United States
Mayo Clinic
National Institutes of Health (NIH)

Completed

Biomarkers in Phototherapy of Barrett's Esophagus (BIOBAR)

Barrett's Esophagus | High Grade Dysplasia

United States
University of California, Irvine

Completed

Optical Coherence Tomography of the Gastrointestinal Tract (OCT)

Barrett's Esophagus With or Without Dysplasia | Patients With Early Esophageal or Gastric Cancer | Patients With Intestinal Metaplasia of the Stomach

United States
Bayer

Completed

EffectiveNess of Low-dose Aspirin in Prevention of Cancer in the Stomach and Oesophagus (GastrointEstinal Cancer Prevention) - United Kingdom ("ENgAGE - UK"): Study to Evaluate the Risk of Cancer in the Stomach and Oesophagus Among New Users of Low-dose Aspirin Using the THIN Database in the UK (ENgAGE-UK)

Prevention of Oesophagus Cancer and Stomach Cancer

United Kingdom
Lucid Diagnostics, Inc.

Recruiting

Lucid Registry Study (Lucid Registry)

Barrett Esophagus | Esophageal Adenocarcinoma | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia

United States
University of North Carolina, Chapel Hill
American Society for Gastrointestinal Endoscopy

Completed

Stratifying Risk in Barrett's Esophagus: A Pilot Study for Biomarker-based Patient Management

Barrett's Esophagus | Esophageal Adenocarcinoma | Intestinal Metaplasia | Dysplasia

United States, Netherlands, United Kingdom
CDx Diagnostics
Foundation for Surgical Innovation and Education

Completed

The Evaluation of Patients With Esophageal and Foregut Disorders With WATS (Wide Area Transepithelial Sample With 3-Dimensional Computer-Assisted Analysis) vs. 4-Quadrant Forceps Biopsy

Esophageal Diseases | GERD | Barrett Esophagus | Low Grade Esophageal Glandular Dysplasia

United States
Liverpool University Hospitals NHS Foundation Trust
University Hospital Southampton NHS Foundation Trust

Completed

The Effect of Chemotherapy and Surgery for Cancer on Exercise Capacity

Tumor of Esophagus, Stomach and Duodenum

United Kingdom
Lucid Diagnostics, Inc.

Recruiting

Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC (ESOGUARDBE2)

Barrett Esophagus | Esophageal Adenocarcinoma | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia

United States, Netherlands
Mayo Clinic
Fred Hutchinson Cancer Center

Completed

Probe-based Volumetric Laser Endomicroscopy (pVLE) of Endoscopic Mucosal Resection (EMR) Tissue in Patients With Barrett's Dysplasia (VLE EMR)

Barrett's Esophagus With High Grade Dsyplasia | Early Esophageal Cancer

United States
University of Colorado, Denver

Recruiting

Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance (SWAT-BE)

Barrett Esophagus | Esophageal Adenocarcinoma | Barretts Esophagus With Dysplasia

United States
University of Kansas Medical Center
University of Texas, Southwestern Medical Center at Dallas

Recruiting

Itraconazole to Prevent Recurrent Barrett's Esophagus

Barrett Oesophagitis With Dysplasia

United States
King's College Hospital NHS Trust
King's College London; Danish Epilepsy Centre

Recruiting

Mos-FED (Mosaicism in Focal Epilepsy Cortical Dysplasia Tissue) (MosFED)

Epilepsy | Focal Cortical Dysplasia

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Not yet recruiting

First-in-human Experience Using Novel Ultraflexible Low-impedance Electrode Arrays: an IDEAL Stage 1 Study

Epilepsy | Focal Cortical Dysplasia

United Kingdom
Mayo Clinic

Completed

Endoscopic Tri-Modal Imaging in Patients With Barrett's Esophagus (ETMI)

Early Esophageal Adenocarcinoma | Barretts Esophagus | High Grade Dysplasia

United States, Netherlands
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Esophageal Cytology With FISH in Detecting Esophageal Cancer

Esophagitis | Weight Loss | Gastroesophageal Reflux Disease | Dysphagia | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Dysplasia | High Grade Dysplasia in Barrett Esophagus

United States
Mayo Clinic

Completed

Cryotherapy -BEATS-RF Ablation Trial

Barrett's Esophagus With Persistent Dysplasia or | Early Esophageal Adenocarcinoma Post Radio Frequency Ablation

United States
University of North Carolina, Chapel Hill
Johns Hopkins University; PENTAX of America, Inc.

Recruiting

Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE) (NO FEAR-BE)

Barrett Esophagus | Intestinal Metaplasia | Esophageal Dysplasia

United States
CDx Diagnostics
University of North Carolina, Chapel Hill

Terminated

The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. Registry

Gastroesophageal Reflux | Esophageal Diseases | Barrett Esophagus | Esophageal Dysplasia

United States
Royal Marsden NHS Foundation Trust

Completed

Pre-operative Epirubicin, Cisplatin, and Capecitabine in Patients With Newly Diagnosed Localised Oesophageal Adenocarcinoma

Adenocarcinoma of Oesophagus

United Kingdom
Medacta International SA

Active, not recruiting

AMIStem Primary Hip System Prospective Post-marketing Multi-centre Surveillance Study

Arthritis | Osteoarthritis | Avascular Necrosis | Congenital Hip Dysplasia | Fracture of the Femoral Neck or Head

Switzerland, United Kingdom
Universitätsklinikum Hamburg-Eppendorf

Terminated

Piecemeal Versus En Bloc Resection of Large Rectal Adenomas (PERLA)

Colorectal Adenomatous Polyp | Colorectal Adenoma With Mild Dysplasia | Colorectal Adenoma With Severe Dysplasia | Colorectal Low Grade Intraepithelial Neoplasia | Colorectal High Grade Intraepithelial Neoplasia

Germany, United Kingdom
The Royal Orthopaedic Hospital NHS Trust

Recruiting

Patient Specific Guides and Surgical Planning for Periacetabular Osteotomy; Post Marketing Evaluation Study (MyPAO)

Acetabular Dysplasia | Periacetabular Osteotomy | Pelvic Osteotomy

United Kingdom
CDx Diagnostics

Recruiting

Clinical Utility of WATS3D: A 5-Year Prospective Study

Esophageal Diseases | Gastro Esophageal Reflux | Barrett Esophagus | Esophageal Dysplasia

United States
Royal Marsden NHS Foundation Trust
Eli Lilly and Company; AstraZeneca; Clovis Oncology, Inc.; MedImmune LLC

Recruiting

Planning Treatment for Oesophago-gastric Cancer: a Maintenance Therapy Trial (PLATFORM)

Adenocarcinoma of the Stomach | Adenocarcinoma of the Oesophagus | Adenocarcinoma of the Gastro-oesophageal Junction

United Kingdom
Johns Hopkins University
Pentax Medical

Active, not recruiting

Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium (ColdPlay2)

Esophageal Cancer | Barrett's Esophagus | Esophageal Squamous Dysplasia

United States
Royal Marsden NHS Foundation Trust

Completed

Neoadjuvant Epirubicin, Cisplatin and Capecitabine (ECX) Followed by Definitive Chemoradiation With/Without Surgery for Squamous Cell Carcinoma of the Oesophagus

Oesophageal Carcinoma

United Kingdom
NHS Lothian
University of Edinburgh

Recruiting

Nexus Evaluation Primary Trident II Uncemented Shell (NEPTUNE)

Hip Dysplasia | Hip Osteoarthritis | Hip Arthropathy | Arthritis of Hip

United Kingdom
University of Alabama at Birmingham
Aventis Pharmaceuticals; Pharmacia and Upjohn

Completed

Irinotecan and Taxotere With Radiotherapy as Preoperative Treatment in Resectable Esophageal Cancer

Esophageal Cancer | Cancer of the Esophagus | Esophageal Neoplasm | Esophagus Cancer | Cancer of Esophagus

United States

Clinical Trials on Severe Dysplasia of Esophagus in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Morocco

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations