Clinical Trials on Severe Familial Hypercholesterolemia in Switzerland

Total 134 results

greenTEG AG
University Children's Hospital, Zurich; Children's Hospital of Eastern Switzerland...

Suspended

Development of a Fever Detection Algorithm Based on Non-invasive Skin-based Sensor Values in Infants up to 18 Months of Age

Fever

Switzerland
Idorsia Pharmaceuticals Ltd.

Terminated

Tezosentan in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, France, Switzerland
University Hospital, Geneva
Pamukkale University; Hospices Civils de Lyon; Hospital Clinic of Barcelona; German... and other collaborators

Unknown

Preop Hemodialysis or Intraop Ultrafiltration for Patients With Severe Renal Dysfunction Undergoing Open Heart Surgery (SeRenaD-CPB)

Cardiovascular Disease | Non-Dialysis Dependent Severe Renal Dysfunction

Germany, France, Spain, Switzerland, Turkey
Patricia Schlagenhauf
University Hospital, Geneva; Swiss Tropical & Public Health Institute; ETH Zurich and other collaborators

Not yet recruiting

Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and Malaria (ITIT)

Diarrhea | Malaria | Influenza | SARS-CoV Infection | Dengue | Chikungunya | Zika | Travel-Related Illness | MERS

Switzerland
Deutsches Herzzentrum Muenchen
Infraredx Inc

Recruiting

NIRS-IVUS to Improve Assessment of Coronary Artery Disease Severity in Patients Referred for Transcatheter Aortic Valve Implantation (IMPACTavi)

Coronary Artery Disease | Aortic Stenosis, Severe

Switzerland, Germany
University of Zurich

Recruiting

Pyrexia Management Using an IL-6 Antibody in BRAF+ Melanoma Patients Treated With Dabrafenib/ Trametinib +/- Immunotherapy (Nov IIT- Pyrex)

Pyrexia

Switzerland
Prof. Dr. Jörg Leuppi
GlaxoSmithKline; Novartis; AstraZeneca; Lungenliga Schweiz

Recruiting

Swiss Severe Asthma Register

Severe Asthma

Switzerland
University Hospital, Basel, Switzerland
Swiss Personalized Health Network (SPHN); Personalized Health and Related Technologies...

Terminated

Molecular Biomarkers for Sepsis

Sepsis | Infection, Bacterial | Severe Community-acquired Pneumonia (sCAP)

Switzerland
Insel Gruppe AG, University Hospital Bern
ETH Zurich

Not yet recruiting

Swiss 2024 Continous Fever Monitoring in Pediatric Oncology Patients

Pediatric Oncology Patients With Risk for Infections

Switzerland
University of Zurich

Unknown

Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Peritoneal Cancer

Switzerland
Emergex Vaccines Holding Ltd.
University of Lausanne Hospitals; Center for Primary Care and Public Health...

Completed

A Phase-I Study of a Nanoparticle-based Peptide Vaccine Against Dengue Virus

Dengue

Switzerland
MeMed Diagnostics Ltd.
University Hospital, Geneva

Completed

Validation of a Proteomic Signature and Assessment of Viremia in Children With Fever Without Source

Infectious Disease | Fever | Viremia

Switzerland
Imperial College Healthcare NHS Trust

Completed

Hospital Admissions in Children Aged 3 Months to 5 Years Presenting With Fever to the Emergency Department

Fever

Switzerland, United Kingdom
University Hospital Inselspital, Berne
Instituto de Cardiología Paredes-Horna, Arequipa; Hospital Nacional Carlos...

Completed

Rheumatic Heart Disease in Peru: Prevalence and Cardiovascular Outcomes Among Schoolchildren

Rheumatic Heart Disease | Acute Rheumatic Fever

Peru, Switzerland
Swiss Pediatric Oncology Group

Completed

SPOG 2015 FN Definition. A Multi-center Non-inferiority Trial on Safety of a High Versus Low Temperature Limit Defining Fever in Pediatric Patients With Cancer at Risk for Fever in Chemotherapy-induced Neutropenia

Cancer | Neutropenia | Fever | Pediatrics | Fever in Neutropenia

Switzerland
Actelion

Completed

Bosentan in Children With Pulmonary Arterial Hypertension Extension Study (FUTURE 2)

Pulmonary Arterial Hypertension

United States, France, Netherlands, Italy, Germany, Switzerland, United Kingdom
Actelion

Completed

Bosentan in Children With Pulmonary Arterial Hypertension (FUTURE-1)

Pulmonary Arterial Hypertension

United States, France, Netherlands, Italy, Germany, Switzerland, United Kingdom
University Hospital Inselspital, Berne
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Terminated

CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19 (CONVINCE)

COVID-19 | SARS-CoV Infection

Belgium, Switzerland, Italy
Kantonsspital Aarau
University of Zurich

Unknown

Concurrent Hyperthermia and Chemoradiotherapy in LAPC: Phase II Study (HEATPAC)

Cancer Pancreas

Switzerland
Centre Hospitalier Universitaire Vaudois

Completed

Evaluation of High Speed Laser Doppler Imaging Technology (HSL-DI)

Hay Fever

Switzerland
Kantonsspital Aarau
University Hospital, Zürich; Center for Proton Therapy, Paul Scherrer Institute...

Unknown

Hyperthermia and Proton Therapy in Unresectable Soft Tissue Sarcoma (HYPROSAR)

Soft Tissue Sarcoma

Switzerland
Centre Hospitalier Universitaire Vaudois
Unisanté Centre universitaire de médecine générale et santé publique; FORCE...

Not yet recruiting

Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance (DAR-ARC)

Febrile Neutropenia

Switzerland
University Hospital, Basel, Switzerland

Completed

Probability of Optimal Target Attainment of Amikacin in Patients With Febrile Neutropenia During Treatment for a Hematological Disorder

Febrile Neutropenia (FN)

Switzerland
University of Zurich

Active, not recruiting

Immunological Analysis of Lymph Node Tissue After Intralymphatic Immunotherapy: A Prospective Case Control Study (ILIT-FNA)

Hypersensitivity | Rhinitis, Allergic, Seasonal | Hay Fever | Rhinoconjunctivitis

Switzerland
Novartis Pharmaceuticals

Terminated

Efficacy, Safety, Tolerability and Pharmacokinetics (PK) of Nilotinib (AMN107) in Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

Switzerland, United States, Germany, Singapore, Korea, Republic of, Canada
Sanofi
Regeneron Pharmaceuticals

Completed

Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Hypercholesterolemia

France, Belgium, Austria, Canada, Czechia, Denmark, Finland, Germany, Greece, Hungary, Poland, Romania, Slovakia, Slovenia, Spain, Switzerland
University of Applied Sciences of Western Switzerland
Swiss National Science Foundation; University of Lausanne Hospitals; Réseau d... and other collaborators

Completed

Impact of a Telenursing Service on Satisfaction and Health Outcomes of Children With Inflammatory Rheumatic Diseases

Inflammatory Rheumatism

Switzerland
AstraZeneca

Completed

Real World Study With Benralizumab in Severe Asthma in Switzerland (BEEPS)

Severe Eosinophilic Asthma

Switzerland
Prof. Dr. Jörg Leuppi

Completed

High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study (VitCov)

Covid19 | Vitamin D Deficiency | Corona Virus Infection | ARDS | SARS-CoV Infection | Coronavirus

Switzerland
Roza Umarova

Recruiting

Post-stroke Cognitive Impairment (CogStroke)

Cognitive Performance | First-ever Ischemic Stroke

Switzerland
Abbott Medical Devices

Completed

FlexNav EU CE Mark Study

Symptomatic Severe Aortic Stenosis

Denmark, Switzerland, United Kingdom, Italy
Amgen

Completed

Open-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Hypercholesterolemia

Canada, Netherlands, Spain, Belgium, United States, Russian Federation, Czechia, Mexico, Korea, Republic of, Australia, United Kingdom, Argentina, Israel, France, Hungary, Germany, Greece, Poland, Switzerland, Italy, Brazil, Sweden, Norwa... and more
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
Amgen

Completed

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound (GLAGOV)

Hypercholesterolemia

United States, Canada, Denmark, Germany, Italy, Netherlands, Spain, Sweden, Belgium, Taiwan, Russian Federation, France, Czechia, Mexico, Korea, Republic of, Australia, United Kingdom, Argentina, Israel, Hungary, South Africa, Greece and more
European Society for Blood and Marrow Transplantation
Novartis; Pfizer

Completed

hATG+CsA vs hATG+CsA+Eltrombopag for SAA (RACE)

Severe Aplastic Anemia

Switzerland, Netherlands, France, Italy, Spain, United Kingdom
University Hospital, Basel, Switzerland
Swiss Multiple Sclerosis Registry

Recruiting

A Study to Assess the Potential Impact of Disease Modifying Therapies on COVID-19 Outcomes and the Antibody Response Following an Infection With SARS-CoV-2 in Patients With Multiple Sclerosis Within the Swiss Multiple Sclerosis Cohort. (MS COVID-19)

Multiple Sclerosis | COVID-19 (Severe Coronavirus Disease 2019)

Switzerland
Swiss Hemophilia Network

Recruiting

Swiss Hemophilia Registry

Hemophilia and Other Severe Bleeding Disorders

Switzerland
Pulmonx Corporation

Active, not recruiting

Fissure Closure With the AeriSeal System for CONVERTing Collateral Ventilation Status (CONVERT) (CONVERT)

Emphysema | COPD | Severe Emphysema

United Kingdom, France, Netherlands, Germany, Australia, Italy, Switzerland
Heidelberg University
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAH (ESRA)

Systemic Sclerosis | Pulmonary Vascular Disorder | Primary Pulmonary Hypertension | Other Systemic Involvement of Connective Tissue

Austria, United Kingdom, Germany, France, Switzerland, Italy
Dr Jean Yannis PERENTES

Recruiting

Treatment Pleural Carcinosis of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin Administration (PITHAC)

Carcinoma, Non-Small-Cell Lung | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Mesothelioma, Malignant | Carcinoma Breast Stage IV

Switzerland
Kantonsspital Winterthur KSW
Luzerner Kantonsspital

Not yet recruiting

Skin Cancer and Hyperthermia and Radiotherapy (SAHARA)

Basal Cell Carcinoma | Non-melanoma Skin Cancer | Squamous Cell Carcinoma Skin

Switzerland
Thomas Pilgrim
B.P. Koirala Institute of Health Sciences

Recruiting

Echocardiographic Screening of Pregnant Women During Antenatal Care

Pregnancy Complications | Rheumatic Heart Disease | Valvular Heart Disease

Nepal, Switzerland
Novartis Pharmaceuticals

Completed

Pediatric Study in Children and Adolescents With Severe Plaque Psoriasis

Chronic Severe Plaque-type Psoriasis

Belgium, Italy, Egypt, France, Hungary, Russian Federation, Germany, Israel, Spain, Japan, Estonia, United Kingdom, Poland, Colombia, United States, Latvia, Guatemala, Romania, Switzerland
Dr. med. Carlo Cereda
University Hospital Inselspital, Berne; CLINICA HILDEBRAND CENTRO DI RIABILITAZIONE... and other collaborators

Unknown

Rehabilitation Combined With Bihemispherictranscranial Direct Current Stimulation in Subacute Ischemic Stroke (RECOMBINE)

Ischemic Stroke | First Ever Clinical Stroke | Subacute Phase | Persistent Hemiparesis of Upper Extremity

Switzerland
Actelion

Completed

Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension. (TRACE)

Pulmonary Arterial Hypertension

United States, United Kingdom, Ireland, Germany, Austria, France, Norway, Portugal, Sweden, Switzerland
Nantes University Hospital

Completed

Impact of a PCT(Procalcitonin) Rapid Test -Based Approach on ATB (Antibiotics) Use in Children With Fever Without Source (DIAFEVER)

Fever Without Source

France, Switzerland
Swiss Pediatric Oncology Group
Bayer; GlaxoSmithKline; Swiss Cancer League

Terminated

Low-risk Fever and Neutropenia in Children With Cancer: Safety and Efficacy of Oral Antibiotics in an Outpatient Setting

Cancer | Neutropenia | Fever

Germany, Netherlands, Switzerland
Vertex Pharmaceuticals Incorporated

Recruiting

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1 | Impaired Hypoglycemic Awareness | Severe Hypoglycemia

United States, Norway, Italy, Canada, France, United Kingdom, Switzerland, Netherlands, Germany
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; Mach Gaensslen Foundation; Baxalta Innovations...

Recruiting

Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome) (TTP registry)

Thrombotic Thrombocytopenic Purpura | Congenital Thrombotic Thrombocytopenic Purpura | Familial Thrombotic Thrombocytopenic Purpura | Thrombotic Thrombocytopenic Purpura, Congenital | Upshaw-Schulman Syndrome

United States, Austria, Czechia, Germany, Japan, Norway, Switzerland
AbbVie (prior sponsor, Abbott)

Completed

Open Label Continuation Study in Moderate to Severe Psoriasis

Moderate to Severe Plaque Psoriasis

United States, Austria, Belgium, Canada, Denmark, Finland, France, Germany, Greece, Italy, Spain, Sweden, Switzerland, United Kingdom

Clinical Trials on Severe Familial Hypercholesterolemia in Switzerland

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