Clinical Trials on Severe Haemophilia A in Spain

Total 565 results

Fundación para la Investigación Biosanitaria del...
Instituto de Salud Carlos III; Instituto de Investigación Marqués de Valdecilla

Recruiting

A Trial of Fosfomycin vs Ciprofloxacin for Febrile Neutropenia (FOVOCIP)

Febrile Neutropenia

Spain
Eli Lilly and Company

Completed

Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)

Severe Sepsis

United States, Belgium, Spain, France, Finland, Germany, Canada, United Kingdom, Puerto Rico
Novartis Pharmaceuticals

Completed

Eltrombopag Combined With Cyclosporine as First Line Therapy in Patients With Severe Acquired Aplastic Anemia (SOAR)

Severe Aplastic Anemia

Spain, Italy, Hong Kong, Thailand, Korea, Republic of, Mexico, Turkey, India, Brazil
GlaxoSmithKline

Completed

Comparison of Adjuvanted Hepatitis B Vaccine to Double Dose of Engerix™-B in Pre- /Haemodialysis Patients Aged ≥15 Years

Hepatitis B

Spain, Czech Republic, Malaysia
Valme University Hospital
Hospital Universitario Virgen Macarena; Hospital Universitario Reina Sofia... and other collaborators

Completed

Hepatic Safety of Currently Used Antiretroviral Regimens in Patients With Chronic Hepatitis Under Real Life Conditions

Hepatitis C, Chronic | Hepatitis B, Chronic | Human Immunodeficiency Virus

Spain
Grupo Espanol Multidisciplinario del Cancer Digestivo

Completed

Study of Oxaliplatin and Sorafenib Combination to Treat Gastric Cancer Relapsed After a Cisplatin Based Treatment

Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (Relapsed After a Cisplatin Based Treatment)

Spain
Ionis Pharmaceuticals, Inc.

Recruiting

A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)

Severe Hypertriglyceridemia

United States, South Africa, Spain, Israel, Australia, Sweden, Netherlands, Canada, Poland, Denmark, Hungary, Bulgaria, Czechia, Italy, France, Norway, New Zealand, Slovakia, Turkey, United Kingdom
Oncostellae S.L

Completed

Study of OST-122 in Patients With Moderate to Severe Ulcerative Colitis

Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic Severe

Spain, Ukraine
Novartis Pharmaceuticals

Completed

Pediatric Study in Children and Adolescents With Severe Plaque Psoriasis

Chronic Severe Plaque-type Psoriasis

Belgium, Italy, Egypt, France, Hungary, Russian Federation, Germany, Israel, Spain, Japan, Estonia, United Kingdom, Poland, Colombia, United States, Latvia, Guatemala, Romania, Switzerland
Shaare Zedek Medical Center

Completed

Manipulating the Microbiome in IBD by Antibiotics and FMT (FMT)

Exacerbation of Ulcerative Colitis | Ulcerative Colitis, Active Severe | Crohn's Colitis

Israel, Italy, Canada, Finland, Poland, Spain
Novartis Pharmaceuticals

Completed

Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis

Moderate to Severe Chronic Plaque-type Psoriasis

Belgium, Spain, Russian Federation, Germany, United States, Czechia, Peru, Poland, Estonia
Emergent BioSolutions

Completed

Exploring Safety & Clinical Benefit of Anti-Influenza Immunoglobulin Intravenous in Hospitalized Adults With Influenza A

Influenza A H3N2 | Influenza A H1N1

United States, Spain, Canada, Puerto Rico
89bio, Inc.

Recruiting

To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia (ENTRUST)

Severe Hypertriglyceridemia

United States, Bulgaria, Canada, Latvia, Spain, Austria, Belgium, Czechia, Georgia, Hungary, Poland, Puerto Rico, Argentina, Chile, France, Germany, United Kingdom, India, Italy
Hospitales Universitarios Virgen del Rocío
Instituto de Biomedicina de Sevilla

Enrolling by invitation

Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis (SeVIHPrEP)

Hepatitis, Viral, Human | HIV Infection Primary | Sexually Transmitted Infections, Excluding HIV and Hepatitis

Spain
Agennix

Suspended

Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis (OASIS)

Severe Sepsis

United States, Spain, Belgium, France, United Kingdom, Canada, Israel, Germany, Denmark, Netherlands
Hospital Universitari de Bellvitge
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Recruiting

Efficacy of Extended Infusion of β-lactam Antibiotics for the Treatment of Febrile Neutropenia in Hematologic Patients (BEATLE)

Febrile Neutropenia

Spain
MedtronicNeuro

Completed

SISTERS: Spasticity In Stroke Study - Randomized Study (SISTERS)

Severe Spasticity

Belgium, Spain, United States, Austria, Germany, Italy, Netherlands, Slovenia, United Kingdom
AstraZeneca

Completed

Characterisation of Patients With Severe Asthma in Primary and Secondary Care Settings in Europe Reported to be Eligible for Biological Therapy (RECOGNISE)

Severe Asthma

Hungary, Germany, Bulgaria, Czechia, France, Greece, Italy, Netherlands, Poland, Romania, Slovenia, Spain
Ionis Pharmaceuticals, Inc.

Recruiting

A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia

Severe Hypertriglyceridemia

United States, Belgium, Spain, Poland, Taiwan, France, Bulgaria, Netherlands, Brazil, Italy, Czechia, Canada, Greece, Portugal, Argentina, Malaysia, Mexico, Slovakia, Sweden, Hungary, India, Romania, Lithuania
Maimónides Biomedical Research Institute of Córdoba

Not yet recruiting

Evaluation of Orthohepevirus C Infection as an Emerging Cause of Zoonotic Origin Disease

Liver Diseases | Hepatitis | Liver Disease Chronic | Chronic Hepatitis | Acute Hepatitis

Spain
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

Severe Hypertriglyceridemia

Finland, United States, France, Israel, Netherlands, Denmark, Spain, Australia, United Kingdom, Germany, Italy, Canada, Czechia, Turkey, Hungary, Bulgaria, New Zealand, Sweden, South Africa, Poland, Norway, Portugal, Slovakia
Ultragenyx Pharmaceutical Inc
Abeona Therapeutics, Inc

Enrolling by invitation

A Long-term Follow-up Study of Patients With MPS IIIA Treated With ABO-102

Mucopolysaccharidosis III-A

United States, Australia, Spain
AstraZeneca

Completed

A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock

Septic Shock | Severe Sepsis

Czech Republic, France, Spain, Finland, Canada, Australia, Belgium
Digna Biotech S.L.

Completed

A Phase I/II Clinical Trial With Interferon Alfa 5 in Treatment-Experienced Patients With Genotype-1 Chronic Hepatitis C

Chronic Hepatitis C Virus Infection | Genotype 1 | Treatment-Experienced Patients | Relapses

Spain
Novartis Pharmaceuticals

Completed

Study of Safety, Tolerability, and Efficacy of Secukinumab in Subjects With Moderate to Severe Palmoplantar Psoriasis (GESTURE)

Moderate to Severe Palmoplantar Psoriasis

Belgium, United States, Hungary, Russian Federation, Turkey, Australia, Israel, Netherlands, Portugal, Spain, United Kingdom, Norway, Slovakia, Canada, Finland
GlaxoSmithKline

Completed

Long Term Follow-up Study at Years 2, 3, 4 and 5 Where 2 Dosing Schedules of the Combined Hepatitis A and B Vaccine Were Compared

Hepatitis B | Hepatitis A

Australia, Belgium, Spain
AbbVie (prior sponsor, Abbott)

Completed

Open Label Continuation Study in Moderate to Severe Psoriasis

Moderate to Severe Plaque Psoriasis

United States, Austria, Belgium, Canada, Denmark, Finland, France, Germany, Greece, Italy, Spain, Sweden, Switzerland, United Kingdom
Bausch Health Americas, Inc.

Terminated

P3 Study Brodalumab in Treatment of Moderate to Severe Plaque Psoriasis (AMAGINE-2)

Moderate to Severe Plaque Psoriasis

United States, Austria, France, Poland, Australia, Czechia, Canada, Hungary, Portugal, Spain, Netherlands
BioCryst Pharmaceuticals

Terminated

Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN) (RENEW)

Immunoglobulin A Nephropathy | Membranous Nephropathy | Complement 3 Glomerulopathy

France, Italy, Spain, United Kingdom
Novartis Pharmaceuticals

Recruiting

A NIS of Alpelisib in Combination With Fulvestrant in Postmenopausal Women, and Men, With HR+,HER2- , Locally Advanced or Metastatic Breast Cancer With a PIK3CA Mutation, After Disease Progression Following Endocrine Therapy as Monotherapy, in the Real-world Setting

Hormone Receptor Positive HER2 Negative Breast Cancer With a PIK3CA Mutation

Spain, Italy, Austria
Janssen R&D Ireland

Completed

Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Subjects With Chronic Genotype 4 Hepatitis C Virus Infection

Chronic Hepatitis C | Genotype 4 Chronic Hepatitis C

Spain
LivaNova

Completed

Evaluation of the SafeR Mode in Patients With a Dual Chamber Pacemaker Indication (ANSWER)

Assess the Benefits From the AAISafeR/SafeR Algorithm of Symphony 2550 or REPLYTM DR in a Wide Range of Pacemaker Patients.

Italy, France, Spain, United States, Germany, United Kingdom
Rocket Pharmaceuticals Inc.

Active, not recruiting

Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype A

Fanconi Anemia Complementation Group A

Spain, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy, Tolerability and Safety of Early Introduction of Everolimus, Reduced Calcineurin Inhibitors and Early Steroid Elimination Compared to Standard CNI, Mycophenolate Mofetil and Steroid Regimen in Paediatric Renal Transplant Recipients

Prevention of Acute Rejection in Paediatric Recipients of a Renal Transplant

Germany, United Kingdom, France, Italy, United States, Hungary, Norway, Spain, Argentina, Brazil, Poland, Sweden, Turkey
Ultragenyx Pharmaceutical Inc
Abeona Therapeutics, Inc

Terminated

Gene Transfer Study of ABO-102 in Patients With Middle and Advanced Phases of MPS IIIA Disease

Mucopolysaccharidosis III | Sanfilippo Syndrome | MPS IIIA | Sanfilippo A

United States, Spain, Australia
Eisai Inc.

Completed

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

Severe Sepsis

United States, France, Poland, United Kingdom, Germany, Hong Kong, Taiwan, Spain, Switzerland, Argentina, Belgium, Israel, South Africa, Japan, Canada, Netherlands, Korea, Republic of, Australia, Chile, Brazil, Austria, Italy, Czechia, Portug...
Origin Biosciences

Completed

Study of ORGN001 (Formerly ALXN1101) in Neonates, Infants and Children With Molybdenum Cofactor Deficiency (MOCD) Type A

Molybdenum Cofactor Deficiency, Type A

United States, Spain, Israel, Norway, Turkey, United Kingdom
Synairgen Research Ltd.

Completed

Study to Assess Efficacy and Safety of Inhaled Interferon-β Therapy for COVID-19 (SPRINTER)

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2

United Kingdom, Italy, United States, Portugal, Israel, Germany, Belgium, India, Spain, Netherlands, Argentina, Brazil, Colombia, France, Mexico, Romania, Serbia
BioTech Tools S.A.

Completed

Clinical Efficacy and Safety of a Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis

Hay Fever

Spain, Belgium, Italy
Biotest
AMS Advanced Medical Services GmbH

Completed

A Clinical Trial of Zutectra in Patients Who Recently Received a Liver Transplant (ZEUS)

Hepatitis B

Spain, United Kingdom, France, Italy
Gilead Sciences

Completed

Sofosbuvir/Velpatasvir Fixed Dose Combination in Participants With Chronic Hepatitis C Virus Infection Who Have Received a Liver Transplant

Hepatitis C Virus Infection

Spain, Switzerland, United Kingdom
Bristol-Myers Squibb

Completed

Safety and Efficacy Study in Subjects With Chronic HCV and Underlying Hemophilia (MAGNITUDE)

Hepatitis C Virus

Australia, France, United States, Spain, Italy, Netherlands, Romania, Russian Federation
Germans Trias i Pujol Hospital
H. Lundbeck A/S; Hoffmann-La Roche

Completed

Efficacy and Safety of Escitalopram for Prevention of Depression Induced by Peg-Interferon in Hepatitis C Patients

Hepatitis C, Chronic | Major Depressive Disorder

Spain
Novartis Pharmaceuticals

Completed

Lipoprotein(a) in Patients With Cardiovascular Disease (CVD)

Cardiovascular Disease and Lipoprotein(a)

China, Germany, United States, Colombia, South Africa, Italy, Spain, Belgium, Egypt, Hungary, Taiwan, Turkey, Japan, Netherlands, Australia, Austria, Canada, Czechia, France, Israel, Switzerland, United Kingdom, Korea, Republic of, Th... and more
HepNet Study House, German Liverfoundation
Hannover Medical School; German Center for Infection Research

Completed

The Hepatitis Delta International Network (HDIN)

Hepatitis D

Germany, Austria, Belgium, Brazil, Georgia, Greece, Italy, Moldova, Republic of, Pakistan, Romania, Spain, Vietnam
sigma-tau i.f.r. S.p.A.
SciClone Pharmaceuticals

Completed

Thymosin Alpha-1 in Combination With Peg-Interferon Alfa- 2a and Ribavirin for the Therapy of Chronic Hepatitis C Nonresponsive to the Combination of IFN and Ribavirin.

Chronic Hepatitis C

Spain, Italy, France, Germany, Greece
Parc Sanitari Pere Virgili
Althaia Xarxa Assistencial Universitària de Manresa; Hospital Vall d'Hebron; Consorci... and other collaborators

Completed

Diabetes as an Accelerator of Cognitive Impairment and Alzheimer's Disease (DIALCAT)

Patients Aged 65-85 (Both Included) | Diagnosed of Mild Cognitive Impairment | Diagnosed of Type 2 Diabetes in Active Treatment (Hypoglycemic Agents) for a Period ≥5 Years

Spain
UCB Biopharma SRL

Completed

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis (BE RADIANT)

Moderate to Severe Chronic Plaque Psoriasis | Chronic Plaque Psoriasis

United States, Australia, Belgium, Canada, France, Germany, Netherlands, Poland, Spain, Turkey, United Kingdom
Abbott Medical Devices

Recruiting

Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation (VANTAGE)

Symptomatic Severe Aortic Stenosis

Spain, Denmark, United Kingdom, France, Italy, Australia, Germany, Netherlands, Switzerland, Austria
Fundación Pública Andaluza para la gestión de la...

Completed

Study to Reduce Duration of Antibiotic Therapy in Haematological Patients With Fever and Neutropenia (HOWLONG)

Febrile Neutropenia

Spain

Clinical Trials on Severe Haemophilia A in Spain

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