Clinical Trials on Severe Sepsis or Septic Shock in Netherlands

Total 135 results

Amsterdam UMC, location VUmc
Stichting Nuts Ohra; Nederlandse Internisten Vereniging ( Dutch Association...

Completed

Prehospital Antibiotics Against Sepsis Trial (PHANTASi)

Sepsis | Septic Shock | Severe Sepsis

Netherlands
Sphingotec GmbH
Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Hopital... and other collaborators

Completed

Adrenomedullin and Outcome in Severe Sepsis and Septic Shock (AdrenOSS)

Septic Shock | Severe Sepsis

France, Belgium, Germany, Italy, Netherlands
Medical Centre Leeuwarden

Completed

The Effect of Ketanserin on the Microcirculation in Sepsis

Septic Shock | Severe Sepsis

Netherlands
Amsterdam UMC, location VUmc
UMC Utrecht; Dijklander Ziekenhuis; Medical Center Haaglanden; Elisabeth-TweeSteden... and other collaborators

Completed

Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's) (SAPS)

Sepsis | Septic Shock | Severe Sepsis

Netherlands
Radboud University Medical Center

Completed

The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis

Sepsis | Septic Shock

Netherlands
Medisch Spectrum Twente

Unknown

Resuscitation Strategies in Septic Shock (ReSSeS)

Septic Shock | Critically Ill

Netherlands
Danish Procalcitonin Study Group
Lundbeck Foundation; TRYG Foundation

Terminated

The Cooling And Surviving Septic Shock Study (CASS) (CASS)

Septic Shock

Netherlands, Denmark, United States
A.P.J. Vlaar
Maastricht University Medical Center; Maastricht University; Matisse Pharmaceuticals

Completed

Intravenously Administered M6229 in Critically Ill Sepsis Patients (HistoSeps)

Sepsis | Critical Illness | Septic Shock

Netherlands
Adrenomed AG

Completed

Treatment of Patients With Early Septic Shock and Bio-Adrenomedullin(ADM) Concentration > 70 pg/ml With ADRECIZUMAB (AdrenOSS-2)

Septic Shock

France, Belgium, Germany, Netherlands
Ferring Pharmaceuticals

Terminated

Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical Trial (SEPSIS-ACT)

Septic Shock

United States, Belgium, Denmark, France, Netherlands
Radboud University Medical Center

Recruiting

Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients. (PHARAOH)

Sepsis | Septic Shock | Critically Ill | Infection, Bacterial

Netherlands
Inotrem

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of 3 Doses of MOTREM in Patients With Septic Shock

Shock, Septic

Belgium, France, Netherlands, Spain
Eli Lilly and Company

Completed

Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock

Sepsis

Italy, United Kingdom, United States, Germany, Spain, Belgium, France, Australia, Czech Republic, Netherlands, Canada, Mexico, New Zealand, Finland, Portugal, Brazil, India, Switzerland
Medical Centre Leeuwarden

Completed

The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis (NISMIS)

Sepsis | Septic Shock

Netherlands
Radboud University Medical Center

Completed

Effects of Alkaline Phosphatase on Renal Function in Septic Patients

Shock | Septic | Severe

Netherlands
Amsterdam University Medical Centers (UMC), Location...
Amsterdam UMC, location VUmc; Flevoziekenhuis

Recruiting

Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room (BIOSEP)

Infections | Sepsis | Septic Shock | Infection, Bacterial | Sepsis, Severe | Infection Viral | Infections, Respiratory

Netherlands
Hadassah Medical Organization
European Society of Intensive Care Medicine; International Sepsis Forum; The...

Completed

Corticosteroid Therapy of Septic Shock - Corticus (Corticus)

Shock, Septic

United Kingdom, Germany, Austria, Belgium, France, Israel, Italy, Netherlands, Portugal
Catharina Ziekenhuis Eindhoven
Erasmus Medical Center

Completed

Mean Systemic Filling Pressure Continuous Diuretics Critical Care Patients

Heart Diseases | Heart Failure | Sepsis | Septic Shock | Surgery | Critically Ill

Netherlands
Onze Lieve Vrouwe Gasthuis

Unknown

Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis

Severe Sepsis | Microcirculation

Netherlands
University Hospital, Bordeaux
Ministry of Health, France

Completed

Haemofiltration Study : IVOIRE (hIgh VOlume in Intensive Care) (IVOIRE)

Shock, Septic | Renal Failure, Acute

France, Belgium, Netherlands
Erasmus Medical Center

Unknown

Peripheral Perfusion Targeted Fluid Management

Sepsis | Severe Sepsis

Netherlands
prof. dr. Frans B. Plötz
Dutch Society of Pediatrics; Zorgevaluatie Nederland; Care4Neo; everywhereIM

Recruiting

Safely Reduce Newborn Antibiotic Exposure With the Early-onset Sepsis Calculator

EOS | Early-Onset Sepsis, Neonatal

Netherlands
Maastricht University Medical Center

Completed

Towards a High-fat Feeding Intervention Study: Identification of Markers for Inflammation and Organ Damage

Sepsis | Systemic Inflammatory Response Syndrome

Netherlands
Jip Groen
InBiome

Recruiting

Molecular Culture for the Diagnosis of Neonatal Sepsis

Microbial Colonization | Neonatal Infection | Neonatal Sepsis, Early-Onset | Microbial Disease | Clinical Sepsis | Culture Negative Neonatal Sepsis | Neonatal Sepsis, Late-Onset | Culture Positive Neonatal Sepsis

Netherlands
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

L-citrulline Supplementation During Sepsis

Sepsis | Multiple Organ Failure

Netherlands
Amsterdam UMC, location VUmc

Completed

Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients

Sepsis | Systemic Inflammatory Response Syndrome | Trauma | Multiple Organ Failure

Netherlands
Jip Groen
InBiome

Recruiting

Molecular Culture for the Diagnosis of Pediatric Sepsis (CHAMPIONS)

Sepsis | Microbial Colonization | Infection, Bacterial | Antibiotic Side Effect | Sepsis Bacterial | Sepsis, Neonatal

Netherlands
Agennix

Suspended

Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis (OASIS)

Severe Sepsis

United States, Spain, Belgium, France, United Kingdom, Canada, Israel, Germany, Denmark, Netherlands
Erasmus Medical Center

Recruiting

Pentoxifylline Dose Optimization in Neonatal Sepsis

Neonatal Late Onset Sepsis

Netherlands, Poland
Eisai Inc.

Completed

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

Severe Sepsis

United States, France, Poland, United Kingdom, Germany, Hong Kong, Taiwan, Spain, Switzerland, Argentina, Belgium, Israel, South Africa, Japan, Canada, Netherlands, Korea, Republic of, Australia, Chile, Brazil, Austria, Italy, Czechia, Portug...
UMC Utrecht

Terminated

The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients (POSEIDON)

Sepsis | Multiple Trauma | Innate Immune Response | Multiple Organ Dysfunction Syndrome | Disorder of Neutrophils

Netherlands
Amsterdam UMC, location VUmc

Completed

Renal Resistive Index in Patients With Shock

Septic Shock | Cardiogenic Shock | Kidney Failure, Acute | Hypovolemic Shock

Netherlands
Franciscus Gasthuis
Erasmus Medical Center

Completed

Reduction of Intravenous Antibiotics In Neonates (RAIN)

Neonatal Infection | Neonatal SEPSIS

Netherlands
UMC Utrecht
Prothya Biosolutions

Terminated

Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture (CAESAR)

Sepsis | Inflammation | Trauma | Multiple Organ Dysfunction Syndrome

Netherlands
AM-Pharma

Completed

Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis

Sepsis | Multiple Organ Dysfunction Syndrome

Netherlands, Belgium
Radboud University Medical Center
UMC Utrecht

Completed

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells (LPS-BM)

Sepsis, Endotoxemia, Immunosuppression

Netherlands
Sirtris, a GSK Company
GlaxoSmithKline

Completed

Effect of SRT2379 on Endotoxin-Induced Inflammation

Sepsis

Netherlands
GlaxoSmithKline

Completed

Effect of SRT2104 on Endotoxin-induced Inflammation

Sepsis

Netherlands
Sirtris, a GSK Company
GlaxoSmithKline

Completed

Effect of Multiple Dose Levels of SRT2379 on Endotoxin-Induced Inflammation

Sepsis

Netherlands
Tigenix S.A.U.

Completed

Randomized, Parallel Group, Placebo Control, Unicentric, Interventional Study to Assess the Effect of Expanded Human Allogeneic Adipose-derived Mesenchymal Adult Stem Cells on the Human Response to Lipopolysaccharyde in Human Volunteers (CELLULA)

Sepsis

Netherlands
University Medical Center Nijmegen

Unknown

Respiratory Muscle Dysfunction in Critically Ill Patients

Sepsis | Mechanical Ventilation

Netherlands
Medical Centre Leeuwarden

Completed

Relation Between the Increase of Peripheral Edema by Fluid Therapy and the Decrease in Microcirculatory Vesseldensity

Sepsis | Edema

Netherlands
Radboud University Medical Center

Completed

The AOT (Acridine Orange and Taurolidine) Trial

Sepsis | Infection | Parenteral Nutrition

Netherlands
W.J. Wiersinga, MD, PhD
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

The Role of the Microbiota in the Systemic Immune Response (MISSION-1)

Sepsis | Healthy

Netherlands
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...
Leiden University Medical Center

Completed

Insufficient Oxygenation in Septic Patients (INOX-SEPSIS)

Sepsis | Fluid Therapy | Critical Care | Oxygen | Mitochondria

Netherlands
Radboud University Medical Center

Completed

Effects of BCG on Immune Response

Sepsis

Netherlands
Asahi Kasei Pharma America Corporation

Completed

Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy

Severe Sepsis | Coagulopathy

Korea, Republic of, United States, Taiwan, Netherlands, United Kingdom, Australia, Canada, Belgium, Israel, Spain, New Zealand, France, Brazil, India, Argentina, Bulgaria, Croatia, Czechia, Finland, Germany, Hungary, Peru, Russian Federation and more
Maastricht University Medical Center
Charles University, Czech Republic; Karolinska University Hospital; Hospices... and other collaborators

Recruiting

European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO (EuroECMO-COVID)

Septic Shock | Extracorporeal Membrane Oxygenation | COVID | SARS-CoV-2 | Cardiogenic Shock | ARDS, Human | Refractory Hypoxemia

Spain, Germany, Netherlands, France, Sweden, Belgium, Austria, Portugal, Poland, United Kingdom, Italy, Lithuania, Czechia, Denmark, Greece, Hungary, Israel, Russian Federation, Switzerland
Radboud University Medical Center
Maastricht University Medical Center

Completed

Anti-inflammatory Effects of Enriched Enteral Nutrition During Human Experimental Endotoxemia (VIHE)

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human Endotoxemia

Endotoxemia

Netherlands

Clinical Trials on Severe Sepsis or Septic Shock in Netherlands

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