Clinical Trials on Severe Pneumonia

Total 13080 results

Novo Nordisk A/S

Completed

Activated Recombinant Human Factor VII in Patients With Dengue Haemorrhagic Fever

Acquired Bleeding Disorder | Dengue Haemorrhagic Fever

Malaysia, Philippines, Thailand
UMC Utrecht
Netherlands: Ministry of Health, Welfare and Sports; Netherlands Vaccine Institute

Completed

Effect of Two Versus Three Pneumococcal Conjugate Vaccinations (MNOES)

Streptococcus Pneumoniae Infection
Sheng-Teng Huang

Completed

Evaluation of KGR Prescriptions in Suppressing COVID-19 Infection.

Coronavirus Disease 2019 | Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Taiwan
Hospices Civils de Lyon

Completed

Host-pathogen Interactions During SARS-CoV-2 Infection (HPI-COVID-19)

Severe Acute Respiratory Syndrome Coronavirus 2 | Infection, Coronavirus

France
Assistance Publique - Hôpitaux de Paris

Completed

EFFICACY and SAFETY OF BEVACIZUMAB (ZIRABEV®) IN PATIENTS WITH SEVERE HYPOXEMIC COVID-19 (BEVA)

Coronaviridae Infections | Nidovirales Infections | RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases | Corona Virus Infection | SARS (Severe Acute Respiratory Syndrome)

France
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); Fred Hutchinson...

Completed

Index Individuals in SARS-CoV-2 Prevention Research Studies (COVID-19 Index Individuals Companion Study) (IICov19PRS)

COVID-19 | Coronavirus Infection | SARS-CoV-2 Infection | SARS (Severe Acute Respiratory Syndrome)

United States
Hospital Universitari Joan XXIII de Tarragona.
Sociedad Española de Medicina Intensiva,critica y unidades coronarias

Recruiting

Characteristics of Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection (COVID-19) (GETCOV-2)

SARS-CoV2 Infection

Spain
Gérond'if

Completed

Personalized Dietary Advice 3 Months After Discharge From Hospitalization in Geriatrics: Effect on Nutritional Status According to Coronavirus Disease 2019 (COVID-19) Status (Positive or Negative) During Hospitalization (COVINUT)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

France
University of Liege
KCE Belgian Healthcare Knowledge Centre

Active, not recruiting

Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation (CONFIDENT)

Covid19 | Respiratory Failure | Corona Virus Infection | Mechanical Ventilation Complication | SARS (Severe Acute Respiratory Syndrome)

Belgium
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Hospital das Clínicas...

Unknown

Adolescents With COVID-19/MIS-C at HCFMUSP

Covid19 | Corona Virus Infection | SARS-CoV Infection | SARS (Severe Acute Respiratory Syndrome)

Brazil
Sanofi

Completed

Study of Two Investigational Pneumococcal Vaccines in Healthy Adults

Pneumococcal Infections | Streptococcus Pneumoniae Infections | Pneumococcal Pneumonia

Switzerland
Sanofi Pasteur, a Sanofi Company

Completed

Study of an Investigational Pneumococcal Vaccine at Three Dose Levels in Healthy Adults

Pneumococcal Infections | Streptococcus Pneumoniae Infections | Pneumococcal Pneumonia

Switzerland
Qilu Hospital of Shandong University
Qianfoshan Hospital; The Second Hospital of Shandong University; Shandong Provincial... and other collaborators

Recruiting

mNGS -Guided Antimicrobial Treatment in Early Severe Community-Acquired Pneumonia Among Immunocompromised Patients (MATESHIP)

Infections | Respiratory Tract Infections | Pneumonia | Community-acquired Pneumonia | Severe Acute Respiratory Infection

China
GlaxoSmithKline

Completed

Primary Vaccination Study With a Pneumococcal Conjugate Vaccine in Healthy Children 6 to 12wks of Age

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Mexico
GlaxoSmithKline

Completed

Primary Vaccination Study With GSK Biologicals' Pneumococcal Vaccine in Healthy Infants in Vietnam

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Vietnam
GlaxoSmithKline

Completed

Assess the Immunogenicity of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Germany
University of Milan

Unknown

Longitudinal Pattern of Streptococcus Pneumoniae Nasopharyngeal Carriage and Antimicrobial Susceptibility in Healthy Children Aged Less Then 5 Years, in the Area of Milan and Surroundings, Lombardy, Italy.

Streptococcus Pneumoniae Nasopharyngeal Carriage

Italy
GlaxoSmithKline

Completed

Primary Vaccination With Either Synflorix™ or Prevenar 13™ or Both Vaccines and Booster Vaccination With Synflorix™

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Mexico
Arto Palmu
GlaxoSmithKline

Completed

Effects of Pneumococcal Vaccine on Nasopharyngeal Carriage

Nasopharyngeal Carriage of Streptococcus Pneumoniae

Finland
Boston Medical Center
Merck Sharp & Dohme LLC

Completed

Streptococcus Pneumonia: Effects of PCV13 on Pneumococcal Carriage

Nasopharyngeal Carriage of S. Pneumoniae

United States
GlaxoSmithKline

Withdrawn

Post-marketing Safety Study of GlaxoSmithKline (GSK) Biologicals' Synflorix™ Vaccine, in Healthy Infants and Children in Sri Lanka

Immunisation Against Streptococcus Pneumoniae
Dompé Farmaceutici S.p.A

Recruiting

Reparixin add-on Therapy to Std Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia

Severe COVID-19 | Infectious Pneumonia

United States, Australia, Turkey, Argentina, Germany, Austria, Italy
GlaxoSmithKline

Completed

Assessment of Antibody Persistence in Children Previously Vaccinated With Pneumococcal Conjugate Vaccine

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Poland
Walvax Biotechnology Co., Ltd.

Completed

Immunogenicity and Safety Study of the 13-valent Pneumococcal Polysaccharide Conjugate Vaccine in 2-71 Months Old Healthy Infants and Toddlers (the Youngest Could be 6 Weeks Old)

Diseases Caused by Streptococcus Pneumoniae Serotypes
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Corticosteroids in Combination With Ruxolitinib in the Management of Checkpoint Inhibitor Pneumonia

Severe Checkpoint Inhibitor Pneumonitis

China
Second Affiliated Hospital, School of Medicine,...

Active, not recruiting

Comparative Analysis of Clinical Parameters and Radiographic Changes of Severe COVID-19

Severe COVID-19

China
University of Erlangen-Nürnberg Medical School

Unknown

Assessment of Efficacy and Safety of Therapy With COVID-19 Convalescent Plasma in Subjects With Severe COVID-19 (IPCO) (IPCO)

Severe COVID-19

Germany
Wuhan Central Hospital

Enrolling by invitation

Risk Identification of Long-term Complications

Severe COVID-19

China
Vascular Biogenics Ltd. operating as VBL Therapeutics

Completed

A Study to Evaluate the Efficacy and Safety of VB-201 in Patients With COVID-19

Severe COVID-19

Israel
Institut National de la Santé Et de la Recherche...
UNITAID

Completed

Impact of Systematic Early Tuberculosis Detection Using Xpert MTB/RIF Ultra in Children With Severe Pneumonia in High Tuberculosis Burden Countries (TB-Speed Pneumonia)

Covid19 | Tuberculosis | Severe Pneumonia

Uganda, Cambodia, Cameroon, Côte D'Ivoire, Mozambique, Zambia
Ophirex, Inc.
Premier Research Group plc

Terminated

Study of Varespladib in Patients Hospitalized With Severe COVID-19 (STAIRS)

Coronavirus Disease 2019 | Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2

United States
Pfizer

Withdrawn

A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19 (EPIC-HOS)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | Coronavirus Disease 2019 (COVID-19) | Immunocompromised | Hospitalization | Child, Hospitalized

United States, Bulgaria
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Recruiting

Early Treatment of Vulnerable Individuals With Non-Severe SARS-CoV-2 Infection (COVERAGE-A)

Covid19 | SARS-CoV2 Infection | Severe Acute Respiratory Syndrome Coronavirus 2 | Covid19 Drug Treatment

Burkina Faso, Guinea
Instituto Nacional de Enfermedades Respiratorias

Unknown

Renal Biomarkers in AKI and COVID-19

Coronavirus Infection | Covid19 | AKI | SARS (Severe Acute Respiratory Syndrome)

Mexico
A.O. Ospedale Papa Giovanni XXIII

Completed

An Observational Study of the Use of Siltuximab (SYLVANT) in Patients Diagnosed With COVID-19 Infection Who Have Developed Serious Respiratory Complications (SISCO)

Severe Acute Respiratory Syndrome (ARDS) Secondary to SARS-COV-2 Infection

Italy
George Papanicolaou Hospital
General Hospital Of Thessaloniki Ippokratio

Recruiting

Generation of SARS-CoV-2-specific T Lymphocytes From Recovered Donors and Administration to High-risk COVID-19 Patients (CoV-2-STs)

Severe COVID-19

Greece
Brno University Hospital

Recruiting

Corticosteroids in Severe COVID-19(ASAP-C Study) (ASAP-C)

Severe COVID-19

Czechia
Daewoong Pharmaceutical Co. LTD.

Terminated

Efficacy and Safety of DWJ1248 With Remdesivir in Severe COVID-19 Patients

Severe COVID-19

Korea, Republic of
Brno University Hospital
European Society of Intensive Care Medicine; European Society of Anaesthesiology...

Completed

Corticosteroids in Severe COVID-19 (ASAP-ESICM/ESAIC Study) (ASAPESICMESAIC)

Severe COVID-19

Czechia
Hospital San Carlos, Madrid

Completed

Safety and Efficacy of Medications COVID-19

Severe Covid-19

Spain
Maimónides Biomedical Research Institute of Córdoba
Dynamic Solutions; Faes Farma, S.A.; Junta de Andalucía - Consejería de Salud...

Completed

Prevention and Treatment With Calcifediol of COVID-19 Induced Acute Respiratory Syndrome (COVIDIOL)

SARS-CoV 2 | COVID19 | Cytokine Storm | Cytokine Release Syndrome | SARS (Severe Acute Respiratory Syndrome)

Spain
Ain Shams University
Misr International University

Completed

Effect of N-acetylcysteine on Oxidative Stress in COVID-19 Patients

Corona Virus Infection | Corona Virus Disease 19 (Covid19) | Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV2)

Egypt
Throne Biotechnologies Inc.

Not yet recruiting

Stem Cell Educator Therapy Treat the Viral Inflammation in COVID-19

Severe Acute Respiratory Syndrome (SARS) Pneumonia
University of British Columbia
Canadian Institutes of Health Research (CIHR); University of Calgary; Alberta... and other collaborators

Completed

CIRN Pneumococcal Conjugate Vaccine 1 vs. 2 Dose Priming Study

Streptococcus Pneumoniae Infection | Invasive Pneumococcal Disease, Protection Against

Canada
aTyr Pharma, Inc.

Completed

Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19

SARS-CoV-2 (COVID-19) Severe Pneumonia

United States, Puerto Rico
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Terminated

Efficacy and Safety of JT001 (VV116) Compared With Favipiravir

Moderate to Severe COVID-19

China, Uzbekistan
National Institute of Respiratory Diseases, Mexico

Completed

Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial) (PHYDRA)

Severe Acute Respiratory Syndrome | COVID-19

Mexico
R-Pharm International, LLC
Data Management 365; K-Research, LLC

Completed

Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19)

COVID-19

Russian Federation
University Hospital, Lille

Recruiting

COVID-19 and VA-LRTI: Second Versus First Wave of the Pandemic (CoVAPid2)

Severe COVID-19

France
National Institute of Respiratory Diseases, Mexico

Completed

Hydroxychloroquine Treatment for Severe COVID-19 Pulmonary Infection (HYDRA Trial) (HYDRA)

Severe Acute Respiratory Syndrome | COVID-19

Mexico

Clinical Trials on Severe Pneumonia

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CROs in Argentina

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