Clinical Trials on Sex Chromosome Aberrations

Total 1520 results

Radboud University Medical Center

Completed

The Effect of Bifocals in Children With Down Syndrome

Visual Acuity at Near | Accuracy of Accommodation | Prevention of Strabismus | Task Readiness

Netherlands
Zafgen, Inc.

Completed

An Efficacy, Safety, and Pharmacokinetics Study of Beloranib in Obese Subjects With Prader-Willi Syndrome

Obesity | Prader-Willi Syndrome | Over-weight

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial

Leukemia
Aarhus University Hospital

Completed

The Intestinal Function in People With Prader-Willi Syndrome

Constipation | Prader-Willi Syndrome | Incontinence

Denmark
Samsung Medical Center

Completed

Characterization of Transcriptional Regulators of Ghrelin Hormone Which Causes Genetic Obesity

Obesity | Prader Willi Syndrome
University of British Columbia

Terminated

Prader-Willi Syndrome and Appetite

Hyperphagia | Prader-Willi Syndrome

Canada
Rutgers, The State University of New Jersey

Completed

Understanding the Role of Gut Microbiota in Hyperphagia in Prader-Willi Syndrome (PWSGUT)

Obesity | Prader-Willi Syndrome

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Treatment of Self-Injurious Behavior in Individuals With Prader-Willi Syndrome

Self-Injurious Behavior | Prader-Willi Syndrome

United States
Shanghai Jiao Tong University School of Medicine

Not yet recruiting

Comparisons of Different Forms of Glucocorticoid on the Recovery of Reproductive Function in Patients With 21α-hydroxylase Deficiency (CGP21)

Congenital Adrenal Hyperplasia

China
Diurnal Limited
National Institutes of Health (NIH)

Withdrawn

Open-label Comparison of Chronocort® Versus Standard Glucocorticoid Replacement Therapy (RESTORE)

Congenital Adrenal Hyperplasia

United States
Region Stockholm

Enrolling by invitation

Effects and Importance of Epinephrine/Adrenalin Deficiency in CAH

Congenital Adrenal Hyperplasia

Sweden
Ain Shams University

Unknown

Final Height in Patients With CAH

Congenital Adrenal Hyperplasia
Boston Children's Hospital

Completed

Dexamethasone Treatment of Congenital Adrenal Hyperplasia

Adrenal Hyperplasia, Congenital

United States
Millendo Therapeutics US, Inc.

Terminated

Nevanimibe HCl for the Treatment of Classic CAH

Congenital Adrenal Hyperplasia

Spain, Israel, France, Brazil, Czechia
Penn State University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Tweens to Teens Project at Penn State (T2T@PSU)

Congenital Adrenal Hyperplasia

United States
Office of Rare Diseases (ORD)

Unknown

Role of the Protein Osteoprotegerin in the Bone Health of Women With Congenital Adrenal Hyperplasia

Adrenal Hyperplasia, Congenital

United States
Diurnal Limited

Completed

A Study of the Efficacy, Safety and Tolerability of Chronocort in Treating CAH

Congenital Adrenal Hyperplasia

United States
Haukeland University Hospital

Unknown

Continuous Subcutaneous Hydrocortisone Infusion in Congenital Adrenal Hyperplasia (CAH)

Adrenal Hyperplasia, Congenital

Norway
Maria I. New
National Center for Research Resources (NCRR); Office of Rare Diseases (ORD)

Completed

Examining Genetic Differences Among People With 21-Hydroxylase Deficiency

21-hydroxylase Deficiency

United States, Brazil
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study Examining Doses of Abiraterone Acetate in Adult Women With 21-Hydroxylase Deficiency

21-hydroxylase Deficiency

United States
Children's Hospital of Fudan University

Recruiting

The Intervention of Obesity in Children With Prader-Willi Syndrome Using Prebiotics and Probiotics

Prader-Willi Syndrome

China
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Alzheimer's Clinical Trials Consortium

Recruiting

Trial-Ready Cohort-Down Syndrome (TRC-DS) (TRC-DS)

Dementia | Alzheimer Disease | Down Syndrome

United States, Spain, United Kingdom
National Institute of Mental Health (NIMH)

Recruiting

Defining the Brain Phenotype of Children With Williams Syndrome

Williams Syndrome | Duplication

United States
Saniona

Completed

Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS) (2016-003694-18)

Confirmed Genetic Diagnosis of Prader-Willi Syndrome

Czechia, Hungary
Weill Medical College of Cornell University
National Institutes of Health (NIH); PWSAUSA

Terminated

Effect of Rimonabant on Weight Gain and Body Composition in Adults With Prader Willi Syndrome (PWS)

Prader-willi Syndrome

United States
Sheba Medical Center
Tel Aviv University

Enrolling by invitation

Motor Deficits and Signal Conduction in Individuals With Williams Syndrome

Williams Syndrome

Israel
Atılım University

Completed

Investigation of Cardiopulmonary Parameters, Motor Development and Muscle Strength in DS With and Without CHD

Down Syndrome | Gross Motor Development Delay | Congenital Heart Defects

Turkey
Riphah International University

Completed

Efficacy of AAC for Functional Communication

Cerebral Palsy | Down Syndrome | Learning Disabilities

Pakistan
NYU Langone Health
Winthrop University Hospital

Withdrawn

Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Unknown

Autonomic Regulation in Prader-Willi Syndrome

Autonomic Dysfunction

Taiwan
Kingkaew Pajareya
Mahidol University

Completed

DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities (RCT/DD)

Cerebral Palsy | Down's Syndrome | Delayed Development

Thailand
Massachusetts General Hospital

Completed

Fat Distribution and Glucose Metabolism in Williams Syndrome

Williams Syndrome

United States
Ferring Pharmaceuticals

Completed

Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome

Hyperphagia in Prader-Willi Syndrome

United States
University of Florida
Foundation for Prader-Willi Research

Completed

Hypoglycemia in Prader-Willi Syndrome

Hypoglycemia | Prader Willi Syndrome

United States
King's College London

Unknown

Memantine and Down's Syndrome

Dementia | Learning Disabilities | Down's Syndrome

United Kingdom
Centre Oscar Lambret
Canceropôle Nord Ouest; Groupement Interrégional de Recherche Clinique et d...

Recruiting

Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring (SUR-CAN)

Glioma | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Adenocarcinoma, Clear Cell | Carcinoma, Small Cell | Ovarian Germ Cell Tumor | Stage I Testicular Seminoma | Stage I Testicular Nonseminomatous Germ Cell Tumor | Borderline Ovarian Tumor | Sex Cord-Stromal Tumor | Mucinous Adenocarcinoma of... and other conditions

France
Perha Pharmaceuticals
Fondation Jérôme Lejeune; European Innovation Council; France 2030 program

Recruiting

Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease (LEUCETTA)

Healthy Volunteers | Down Syndrome | Alzheimer's Disease

France
University of Kansas Medical Center
National Institute on Aging (NIA)

Completed

The Promotion of Physical Activity for the Prevention of Alzheimer's Disease in Adults With Down Syndrome

Alzheimer Disease | Down Syndrome

United States
University Hospital, Toulouse

Completed

Effect of Intranasal Oxytocin on Dysphagia in Children and Adolescents With Prader-Willi Syndrome (DYSMOT)

Prader-Willi Syndrome

France
Children's Oncology Group
National Cancer Institute (NCI)

Withdrawn

Low-Dose Cytarabine in Treating Infants With Down Syndrome and Transient Myeloproliferative Disorder

Leukemia
New York State Institute for Basic Research
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Multicenter Vitamin E Trial in Aging Persons With Down Syndrome

Down Syndrome | Alzheimer's Disease
National Center for Research Resources (NCRR)

Completed

Vitamin D Metabolism and the Williams Syndrome

Williams Syndrome

United States
Rabin Medical Center
Bellerophon

Unknown

Inhaled NO in IPF and COPD During 6 Minute Walk Test

COPD | Oxygen Saturation | IPF | Inhaled Nitric Oxide | Six Minute Walk Test

Israel
Manchester University NHS Foundation Trust

Recruiting

Questionnaire Study to Assess the Outcomes of the Management of Congenital Adrenal Hyperplasia Individuals (CAH-MaS)

Adrenal Hyperplasia, Congenital

United Kingdom
Ain Shams University

Recruiting

Gonadal Changes In Congenital Adrenal Hyperplasia Patients

Congenital Adrenal Hyperplasia

Egypt
Federico II University

Recruiting

Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment (CareOnTIME)

Congenital Adrenal Hyperplasia

Italy
University of Texas Southwestern Medical Center
National Institutes of Health Clinical Center (CC); University of Michigan; Children... and other collaborators

Not yet recruiting

Androgen Reduction in Congenital Adrenal Hyperplasia (ARCH)

Congenital Adrenal Hyperplasia

United States
Millendo Therapeutics, Inc.

Completed

A Study of ATR-101 for the Treatment of Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia

United States
Hospices Civils de Lyon

Completed

Adult Height Prediction in Congenital Adrenal Hyperplasia (OPALE Model)

Congenital Adrenal Hyperplasia

France
Kasr El Aini Hospital

Unknown

Surgical Evaluation of Using the Prepuce in Feminizing Genitoplasty

Congenital Adrenal Hyperplasia

Egypt

Clinical Trials on Sex Chromosome Aberrations

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uruguay

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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