Clinical Trials on Sex Chromosome Abnormalities

Total 27046 results

University of North Carolina, Chapel Hill
National Human Genome Research Institute (NHGRI); East Carolina University; Mission...

Active, not recruiting

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 (NCGENES2)

Neuromuscular Diseases | Movement Disorders | Intellectual Disability | Autism Spectrum Disorder | Microcephaly | Hearing Loss | Genetic Disease | Inborn Errors of Metabolism | Epilepsy; Seizure | Brain Malformation | Hypotonia | Development Delay | Chromosome Abnormality | Dysmorphic Features | Skeletal Dysplasia | Congenital... and other conditions

United States
Shanghai Pulmonary Hospital, Shanghai, China

Unknown

Chromosomal Instability as a Surrogate Biomarker of Drug Resistance in Immunotherapy for Lung Cancer Patients (CINSBDRILCP)

Lung Cancer

China
Northwestern University
ArchieMD

Completed

An Interactive Informed Consent and Education Program for Pregnant Women

Pregnancy | Down Syndrome

United States
National Institute of Neurological Disorders and...
Baylor College of Medicine

Completed

Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes

Prader-Willi Syndrome | DiGeorge Syndrome | Williams Syndrome | Angelman Syndrome | Smith-Magenis Syndrome | Chromosome Abnormalities | Shprintzen Syndrome

United States
dr. Laura C. G. de Graaff-Herder

Recruiting

GROWing Up With Rare GENEtic Syndromes (GROW UR GENES)

Disorders of Sex Development | Congenital Adrenal Hyperplasia | Tuberous Sclerosis | Kallmann Syndrome | Prader-Willi Syndrome | Neurofibromatosis | Rett Syndrome | 22q11 Deletion Syndrome | Turner Syndrome | Noonan Syndrome | Allan-Herndon-Dudley Syndrome | Saethre-Chotzen Syndrome | Congenital Hypopituitarism | Cornelia... and other conditions

Netherlands
Foundation for Angelman Syndrome Therapeutics,...
Queensland University of Technology

Recruiting

The Global Angelman Syndrome Registry (GASR)

Angelman Syndrome

Australia
The Emmes Company, LLC
Boston Children's Hospital; Ionis Pharmaceuticals, Inc.

Completed

Angelman Syndrome Video Assessment (ASVA) Source Material Study (ASVA SMS)

Angelman Syndrome

United States
Fudan University

Completed

Study on the Brain Network of Angelman Syndrome

Angelman Syndrome

China
Hôpital le Vinatier
Hospices Civils de Lyon

Completed

Melatonin in Adults With SMS (SMS-adults)

Smith Magenis Syndrome

France
Eunice Kennedy Shriver National Institute of Child...

Recruiting

Data Collection Study of Pediatric and Adolescent Gynecology Conditions

Disorders of Sex Development (DSD) | Pediatric and Adolescent Cancers of the Genital Tract | Reproductive Endocrine Conditions in Puberty | Structural Gynecologic Conditions Including Vulvar and Vaginal Conditions

United States
Poznan University of Life Sciences

Completed

Lactobacillus Rhamnosus and PCOS Treatment (ProjectPCOS)

Obesity | Polycystic Ovary Syndrome | Hyperandrogenism | Insulin Resistance

Poland
Near East University, Turkey

Completed

Comparison of Serum C Type Natriuretic Peptide Levels Between Polycystic Ovary Syndrome Patients and Healthy Women (CNP)

Polycystic Ovary Syndrome | c Type Natriuretic Peptide | Menstrual Irregularity | Hyperandrogenism

Cyprus
Milton S. Hershey Medical Center
University of Pennsylvania

Completed

Treatment of Hyperandrogenism Versus Insulin Resistance in Infertile Polycystic Ovary Syndrome (PCOS) Women (OWL-PCOS)

Polycystic Ovary Syndrome

United States
University of Oxford
Hoffmann-La Roche; Foundation for Angelman Syndrome Therapeutics UK

Recruiting

Angelman Syndrome Natural History Study-FAST UK

Angelman Syndrome

United Kingdom
Fondazione per la Ricerca Ospedale Maggiore

Completed

Italian Angelman Syndrome Registry Protocol (RISA)

Angelman Syndrome

Italy
Ovid Therapeutics Inc.

Completed

A Study in Adults and Adolescents With Angelman Syndrome (STARS)

Angelman Syndrome

United States, Israel
Boston Children's Hospital

Completed

Study on Tolerability of Levodopa/Carbidopa in Children With Angelman Syndrome

Angelman Syndrome

United States
Semnan University of Medical Sciences

Terminated

Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant

Polycystic Ovary Syndrome | Hyperandrogenism
University of Rochester

Completed

Effect of a Commonly Used Antibiotic, Doxycycline, in Women With Polycystic Ovarian Syndrome (MI-PCOS)

Androgen Excess | Polycystic Ovarian Syndrome (PCOS) | Irregular Menstrual Cycles

United States
Neuren Pharmaceuticals Limited

Recruiting

An Open-Label Study of the Safety, Tolerability, and Pharmacokinetics of Oral NNZ-2591 in Angelman Syndrome (AS-001)

Angelman Syndrome

Australia
University of South Florida

Completed

Minocycline in the Treatment of Angelman Syndrome

Angelman Syndrome

United States
Ovid Therapeutics Inc.

Terminated

An Open-Label Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of OV101 in Individuals With Angelman Syndrome (ELARA)

Angelman Syndrome

United States, Israel
Wen-Hann Tan
Baylor College of Medicine; University of California, San Francisco; Vanderbilt... and other collaborators

Completed

A Trial of Levodopa in Angelman Syndrome

Angelman Syndrome

United States
Vanda Pharmaceuticals

Unknown

Observational Study to Investigate the Melatonin and Cortisol Circadian Rhythms of Individuals With Smith-Magenis Syndrome (SMS)

Smith Magenis Syndrome

United States
Puerta de Hierro University Hospital

Completed

Study to Evaluate the Efficacy and Safety of Minocycline in Angelman Syndrome (A-MANECE)

Angelman Syndrome

Spain
Institute for Neurodegenerative Disorders

Completed

A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions (FPEB)

Parkinson Disease | Alzheimer Disease | Mild Cognitive Impairment | Fragile X Syndrome | Huntington Disease | Autistic Spectrum Disorders

United States
Applied Spectral Imaging Ltd.

Completed

Detection of Chromosomal Aberrations in Urine Samples Using Fluorescent in Situ Hybridization (FISH) (UroVysion Test)

Bladder Cancers

United States
University of Nevada, Las Vegas

Recruiting

Oxygen Uptake Kinetics During Submaximal Exercise in Adults With Down Syndrome

Down Syndrome

United States
Riphah International University

Not yet recruiting

Weight Bearing Exercises With and Without Jaffrey's Core Stability Exercise Training in Children With Down Syndrome.

Down Syndrome

Pakistan
Hoffmann-La Roche

Active, not recruiting

A Study To Investigate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of RO7248824 In Participants With Angelman Syndrome

Angelman Syndrome

United States, Spain, Netherlands, Italy
Ionis Pharmaceuticals, Inc.
Biogen

Active, not recruiting

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

Angelman Syndrome

United States, Israel, Italy, France, Australia, United Kingdom
Riphah International University

Completed

Effects of Rhythmic Aerobic Exercises on Functional Balance in Children With Down Syndrome

Down Syndrome

Pakistan
Massachusetts General Hospital

Active, not recruiting

Transcranial Photobiomodulation With Near-Infrared Light for Language in Individuals With Down Syndrome (TransPhoM-DS)

Down Syndrome

United States
Riphah International University

Completed

Effect Of Pilates On Postural Control And Balance In Children With Down's Syndrome

Down Syndrome

Pakistan
Children's Hospital Medical Center, Cincinnati
Colorado State University

Active, not recruiting

Evaluating Cognitive Outcomes in Down Syndrome (ECODS-2)

Down Syndrome

United States
University of Pittsburgh
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Preventing Obesity Through Parent Empowerment and the Activation of Routines (PrO-PEAR) (PrO-PEAR)

Down Syndrome

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Suspended

Evaluation of Patients With Down Syndrome Compliance to Dental Therapy

Down Syndrome

Italy
Qassim University
Cairo University; Prince Sattam Bin Abdulaziz University

Completed

Effects of Stretch-shortening Cycle Exercises Postural Control in Down Syndrome

Down Syndrome

Saudi Arabia
University of Wisconsin, Madison
Office of the Vice Chancellor for Research and Graduate Education; Wisconsin...

Completed

Down Syndrome Speech Intelligibility Diagnostic Treatment Study

Down Syndrome

United States
Riphah International University

Completed

Effect of Core Stability Exercises and Balance Training in Postural Control Among Down Syndrome

Down Syndrome

Pakistan
Universidad de Granada

Unknown

Assessment of Skills and Behaviors in Children With Down Syndrome

Down Syndrome

Spain
Mansoura University Children Hospital

Completed

the Effect of Cerebrolysin on Physical and Mental Functions of Down Syndrome

Down Syndrome

Egypt
Hacettepe University

Completed

Infants With Down Syndrome on a Different Surface

Down Syndrome

Turkey
University of Michigan
Down Syndrome Association of Toledo

Completed

Effects of Karate in Adolescents With Down Syndrome

Down Syndrome

United States
Advocate Health Care

Completed

Assessing the Feasibility of the Use of Visual Aids in Patient Education in Adults With Down Syndrome (DS)

Down Syndrome

United States
Hoffmann-La Roche

Completed

Non-drug Study to Evaluate the Suitability of Neurocognitive Tests and Functioning Scales for the Measurement of Cognitive and Functioning Changes in Children With Down Syndrome

Down Syndrome

United States, France, Spain
Hoffmann-La Roche

Completed

A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)

Down Syndrome

United States, Spain, Canada, New Zealand, Argentina, Mexico, Singapore
Hoffmann-La Roche

Terminated

A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age

Down Syndrome

United States
University of Seville

Completed

Effects of Infant Massage on Acceptance, Commitment and Conscience of Influence of Parents With Down Syndrome Babies

Parent-Child Relations

Spain
University of Seville

Completed

Effects of Infant Massage on Development of Down Syndrome Babies

Down Syndrome

Spain

Clinical Trials on Sex Chromosome Abnormalities

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