Clinical Trials on Sickle Cell Anemia in Netherlands

Total 1525 results

Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy (RAVOS)

Sickle Cell Disease | Sickle Cell SC Disease | Sickle Cell-SS Disease | Sickle Cell Retinopathy

Netherlands
Pfizer

Completed

A GBT021601 ADME Microtracer Study in Healthy Volunteers

Sickle Cell Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients

Sickle Cell Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
Leiden University Medical Center

Recruiting

Do Alemtuzumab Levels Predict T Cell Chimerism After MSD SCT for SCD? (PREDICT)

Sickle Cell Disease

Netherlands
Sangart

Withdrawn

Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis

Sickle Cell Disease | Anemia, Sickle Cell | Sickle Cell Anemia | Hemoglobin SC Disease | Sickle Cell Disorders | Sickle Cell Hemoglobin C Disease

France, United Kingdom, Netherlands, Turkey, Bahrain, Belgium, Brazil, Lebanon, Qatar
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Preservation and Transfer of HBV Immunity After Allogeneic HSCT for SCD (PROTECT)

Sickle Cell Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Low Dose Iron Chelation as TReatment of Oxidative Damage in Sickle Cell Disease (TROS)

Sickle Cell Disease

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Cerebrovascular Reserve Measurements in Sickle Cell Disease (CRUISE)

Sickle Cell Disease

Netherlands
Sanquin Research & Blood Bank Divisions
Radboud University Medical Center; Erasmus Medical Center; Academisch Medisch... and other collaborators

Unknown

Sickle Cell Disease: Targeting Alloantibody Formation Reduction; Risk Factors, and Genetics (STARRING)

Sickle Cell Disease | Alloimmunization

Netherlands
Dr. Marjon H. Cnossen MD PhD
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Recruiting

Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study) (BRICK)

Sickle Cell Disease | Brain Development Abnormality

Netherlands
Modus Therapeutics AB
Ergomed

Completed

Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD

Sickle-Cell Disease

Netherlands, Oman, Jamaica, Lebanon, Bahrain, Saudi Arabia, Turkey
Pfizer

Completed

Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease

Phase 1 Sickle Cell

United States, United Kingdom, Belgium, Netherlands, Italy
Hospital Universitari Vall d'Hebron Research Institute

Active, not recruiting

GenoMed4ALL: Improving SCD Classification and Prognosis by AI (GenoMed4ALL)

Sickle Cell Disorders

Spain, Netherlands, France, Italy
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Medical Center Groningen; Erasmus Medical Center; Guy's and St Thomas... and other collaborators

Completed

N-Acetylcysteine in Patients With Sickle Cell Disease (NAC)

Sickle Cell Disease

Belgium, Netherlands, United Kingdom
Novartis Pharmaceuticals

Active, not recruiting

Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients (STAND)

Sickle Cell Disease (SCD)

United States, United Kingdom, Germany, Spain, Greece, Italy, Brazil, Lebanon, Turkey, Belgium, France, Jordan, India, Finland, Canada, Colombia, Netherlands, Oman, South Africa, Panama, Ghana
CSL Behring

Completed

Safety of Single Doses of CSL889 in Adult Patients With Sickle Cell Disease

Sickle Cell Disease

United States, United Kingdom, Netherlands
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD). (CROSSWALK-a)

Sickle Cell Disease

United States, Brazil, Italy, Spain, Kenya, Netherlands, United Kingdom, France, South Africa
Imara, Inc.

Terminated

A Study of IMR-687 in Subjects With Sickle Cell Disease

Sickle Cell Disease

United States, Oman, Italy, United Kingdom, Lebanon, Greece, Morocco, Tunisia, Ghana, Kenya, Netherlands, Senegal, Uganda
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD) (CROSSWALK-c)

Sickle Cell Disease

United States, Spain, Brazil, United Kingdom, Italy, Turkey, Kenya, Netherlands, France, South Africa, Lebanon
Pfizer

Active, not recruiting

Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031 (034OLE)

Sickle Cell Disease

United States, Lebanon, United Kingdom, Oman, Turkey, Canada, Egypt, Kenya, France, Italy, Netherlands
Pfizer

Completed

Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) (GBT_HOPE)

Sickle Cell Disease

United States, Italy, France, United Kingdom, Netherlands, Turkey, Egypt, Canada, Jamaica, Kenya, Lebanon, Oman
Agios Pharmaceuticals, Inc.

Recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)

Sickle Cell Disease

United Kingdom, United States, Belgium, Netherlands, Germany, Canada, Brazil, France, Israel, Italy, Lebanon, Oman, Ghana, Kenya, Nigeria, Saudi Arabia, Turkey
Actelion
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study (ASSET-3)

Sickle Cell Anemia | Pulmonary Hypertension

United States, Netherlands, United Kingdom
Novartis Pharmaceuticals

Completed

Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease (STEADFAST)

Sickle Cell Disease (SCD)

United Kingdom, Spain, Greece, Brazil, Turkey, France, United States, Netherlands, Lebanon, Ireland, Panama
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH) (ASSET-2)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Novartis Pharmaceuticals

Completed

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Myelofibrosis | Sickle Cell Disease | Thalassemia | Diamond Blackfan Anemia

United States, Netherlands, Taiwan, Thailand, Italy, Germany, Spain, Canada, Belgium, Greece, Turkey, United Kingdom
Maastricht University Medical Center
Vifor Pharma

Terminated

The Use of Iron Therapy for Patients With Anemia After Caesarean Section (VITAPOP)

Postoperative Anaemia

Netherlands
Bioverativ, a Sanofi company

Active, not recruiting

Safety and Tolerability Study in Adults With Cold Agglutinin Disease Previously Treated With SAR445088 or Never Treated With SAR445088

Autoimmune Haemolytic Anaemia

Netherlands, Germany, Italy, Norway, United Kingdom
Bioverativ, a Sanofi company

Completed

A Safety and Tolerability Study of BIVV020 in Adults With Cold Agglutinin Disease

Autoimmune Haemolytic Anaemia

United States, Germany, Italy, Netherlands, Norway, United Kingdom
European Society for Blood and Marrow Transplantation
CHUGAI sanofi-aventis

Terminated

Randomized Study In Severe Aplastic Anemia Patients Receiving Atg, Cyclosporin A, With Or Without G-CSF (SAA-G-CSF) (SAA-G-CSF)

Aplastic Anaemia

France, Netherlands, Germany, United Kingdom, Switzerland, Italy, Sweden, Greece, Czechia
dr. P. Noordzij
Pharmacosmos A/S

Recruiting

Intravenous Iron to Treat Postoperative Anemia in Older Cardiac Surgery Patients (AGE-ANEMIA)

Iron Deficiency Anemia

Netherlands
Martini Hospital Groningen
dr. J.M. Munster, gynaecologist, principal investigator

Recruiting

The Efficacy of Intermittent Versus Daily Oral Iron Supplementation in Anaemic Pregnant Women. (FER-IDIP)

Pregnancy Related | Iron Deficiency Anemia

Netherlands
Sanquin Research & Blood Bank Divisions
Radboud University Medical Center; Maastricht University Medical Center; UMC... and other collaborators

Recruiting

Data Registry of Auto Immune Hemolytic Anemia (DRAIHA)

Autoimmune Hemolytic Anemia

Netherlands
Catharina Ziekenhuis Eindhoven

Terminated

Pre-operative Treatment With Erythropoietin and Iron Supplement in Cardiac Surgery

Anemia, Iron-Deficiency | Heart; Dysfunction Postoperative, Cardiac Surgery

Netherlands
University Medical Center Groningen
Dutch Kidney Foundation; Vifor Fresenius Medical Care Renal Pharma

Active, not recruiting

Effect of Ferric Carboxymaltose on Exercise Capacity After Kidney Transplantation (EFFECT-KTx)

Iron-deficiency | Transplant-Related Disorder

Netherlands
Vifor Pharma

Completed

Effect of Ferric Carboxymaltose on Exercise Capacity in Patients With Iron Deficiency and Chronic Heart Failure (EFFECT-HF)

Chronic Heart Failure | Iron Deficiency

Netherlands
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...

Completed

Mortality After Transfusion of Ever-pregnant Donor Red Blood Cells (MATER)

Anemia

Netherlands
Rijnstate Hospital

Completed

Optimizing Iron Suppletion After Roux-en-Y Gastric Bypass (Ironsuppletion)

Iron Deficiency

Netherlands
University Medical Center Groningen

Enrolling by invitation

Oxidative Skeletal Muscle Metabolism in Chronic Heart Failure Patients With and Without Iron Deficiency (FERRIFY)

Iron-deficiency | HF - Heart Failure

Netherlands
Vifor Pharma
ICON Clinical Research; American Regent, Inc.

Completed

Ferric Carboxymaltose (FCM) Assessment in Subjects With Iron Deficiency Anaemia and Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD) (FIND-CKD)

Chronic Kidney Disease | Iron Deficiency Anaemia

United Kingdom, United States, Australia, Austria, Belgium, Czech Republic, Denmark, France, Germany, Greece, Italy, Netherlands, Norway, Poland, Portugal, Romania, Spain, Sweden, Turkey
Vifor Pharma
Socar Research SA

Terminated

EFfect of Ferric Carboxymaltose on exercIse CApacity and Cardiac Function in Patients With Iron deficiencY and Chronic Heart Failure (EFFICACY-HF)

Chronic Heart Failure | Iron Deficiency Anemia | Iron Deficiency | Anaemia

France, Netherlands, Denmark, Germany, Israel
Dong-A ST Co., Ltd.

Completed

A Study in Healthy Volunteers to Compare the Profiles of DA-3880 and EU Sourced ARANESP® (Amgen)

Symptomatic Anemia

Netherlands
Radboud University Medical Center

Unknown

The Immunomodulatory Effects of Phlebotomy

Anemia

Netherlands
Maastricht University Medical Center

Recruiting

Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium (COMPETE)

Thrombotic Microangiopathies | Hemolytic-Uremic Syndrome | Hemolytic Uremic Syndrome, Atypical

Netherlands
GlaxoSmithKline

Recruiting

Anemia Studies in CKD: Erythropoiesis Via a Novel PHI Daprodustat - Pediatric (ASCEND-P) (ASCEND-P)

Anaemia

United States, Italy, Spain, France, United Kingdom, Korea, Republic of, Netherlands, Japan, Argentina, Belgium, Turkey
Leiden University Medical Center
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Predicting Response to Iron Supplementation in Patients With Active Inflammatory Bowel Disease (PRIme)

Inflammatory Bowel Diseases | Iron-deficiency | Iron Deficiency Anemia

Netherlands
Prothya Biosolutions

Terminated

Apotransferrin in Patients With β-thalassemia

β-thalassemia Intermedia

Netherlands
Maastricht University Medical Center

Completed

The Change in RetHe - Levels Perioperatively in a Cohort of Colorectal Surgery Patient

Anemia | Colorectal Surgery | Perioperative

Netherlands
Agios Pharmaceuticals, Inc.

Completed

Pyruvate Kinase Deficiency Global Longitudinal Registry Substudy of Protocol AG348-C-008

Pyruvate Kinase Deficiency

United States, Italy, Netherlands

Clinical Trials on Sickle Cell Anemia in Netherlands

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